Felbinac: Difference between revisions

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Felbinac
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Topical
ATC code	M02AA08 (WHO) ;
Legal status
Legal status	UK: P (Pharmacy medicines) ;
Identifiers
	IUPAC name biphenyl-4-ylacetic acid;
CAS Number	5728-52-9;
PubChem CID	3332;
DrugBank	DB07477 ;
ChemSpider	3215 ;
UNII	94WNJ5U8L7;
KEGG	D01675 ;
ChEBI	CHEBI:31597 ;
ChEMBL	ChEMBL413965 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C14H12O2
Molar mass	212.244 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C(O)Cc1ccc(cc1)c2ccccc2;
	InChI InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) ; Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N ;
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VisualWikitext

Latest revision as of 18:30, 10 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) of the arylpropionic acid class, which is used to treat muscle inflammation and arthritis. It is an active metabolite of fenbufen.^[1]

References

↑ Kohler C, Tolman E, Wooding W, Ellenbogen L. (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.

Template:Topical products for joint and muscular pain

[KTWE1980-1] Kohler C, Tolman E, Wooding W, Ellenbogen L. (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.

[1]

@@ Line 1: / Line 1: @@
-{{drugbox
+{{Drugbox
-| IUPAC_name        = 2-(biphenyl-4-yl)acetic acid
+| Watchedfields = changed
-| image             =
+| verifiedrevid = 443752362
-| CAS_number        = 5728-52-9
+| IUPAC_name = biphenyl-4-ylacetic acid
-| ATC_prefix        = M02
+| image = Felbinac.png
-| ATC_suffix        = AA08
-| PubChem           = 3332
+<!--Clinical data-->
-| DrugBank          =
+| tradename =
-| C=14|H=12|O=2
+| Drugs.com = {{drugs.com|international|felbinac}}
-| molecular_weight  = 212.244 g/mol
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
-| bioavailability   =
+| pregnancy_US = <!-- A / B            / C / D / X -->
-| protein_bound     =
+| pregnancy_category =
-| metabolism        =
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| elimination_half-life =
+| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| excretion         =
+| legal_UK = P
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
+| legal_US = <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
+| legal_status =
-| pregnancy_category=
+| routes_of_administration = Topical
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
+<!--Pharmacokinetic data-->
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
+| bioavailability =
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
+| protein_bound =
-| legal_status      =
+| metabolism =
-| routes_of_administration =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number = 5728-52-9
+| ATC_prefix = M02
+| ATC_suffix = AA08
+| PubChem = 3332
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank = DB07477
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 3215
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 94WNJ5U8L7
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D01675
+| ChEBI_Ref = {{ebicite|correct|EBI}}
+| ChEBI = 31597
+| ChEMBL_Ref = {{ebicite|correct|EBI}}
+| ChEMBL = 413965
+<!--Chemical data-->
+| C=14 | H=12 | O=2
+| molecular_weight = 212.244 g/mol
+| smiles = O=C(O)Cc1ccc(cc1)c2ccccc2
+| InChI = 1/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)
+| InChIKey = QRZAKQDHEVVFRX-UHFFFAOYAC
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = QRZAKQDHEVVFRX-UHFFFAOYSA-N
 }}
+__NOTOC__
+{{SI}}
-{{SI}}
+{{CMG}}
-{{EH}}
-'''Felbinac''' (or '''biphenylylacetic acid''') is a topical medicine, belonging to the family of medicines known as [[NSAIDs]], which is used to treat muscle inflammation and arthritis.
+==Overview==
+'''Felbinac''' ([[International Nonproprietary Name|INN]], or '''biphenylylacetic acid''') is a [[topical]] medicine, belonging to the family of medicines known as [[non-steroidal anti-inflammatory drugs]] (NSAIDs) of the arylpropionic acid class, which is used to treat muscle inflammation and [[arthritis]]. It is an active metabolite of [[fenbufen]].<ref name="KTWE1980">{{cite journal | author=Kohler C, Tolman E, Wooding W, Ellenbogen L. | title=A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function | journal=Arzneimittelforschung | volume=30 | issue=4A | pages=702–707 | year=1980 | pmid=6254545}}</ref>
 == References ==
-{{refbegin}}
+{{Reflist|2}}
-* The Merck Index, 12th Edition. 3989
-* Description of Felbinac on Tiscali [http://www.tiscali.co.uk/lifestyle/healthfitness/health_advice/netdoctor/archive/100003440.html]
-{{refend}}
+{{NSAIDs}}
 {{Topical products for joint and muscular pain}}
-{{SIB}}
 [[Category:Non-steroidal anti-inflammatory drugs]]
-[[Category:Drugs]]
+[[Category:Drug]]
-{{WH}}
-{{WikiDoc Sources}}

v t e Non-steroidal anti-inflammatory drug (NSAID) products (primarily M01A and M02A, also N02BA)
Salicylates	Aspirin (acetylsalicylic acid) · Aloxiprin · Benorylate · Diflunisal · Ethenzamide · Magnesium salicylate · Methyl salicylate · Salsalate · Salicin · Salicylamide · Sodium salicylate
Arylalkanoic acids	Diclofenac · Aceclofenac · Acemetacin · Alclofenac · Bromfenac · Etodolac · Indometacin · Indomethacin farnesil · Nabumetone · Oxametacin · Proglumetacin · Sulindac · Tolmetin
2-Arylpropionic acids (profens)	Ibuprofen · Alminoprofen · Benoxaprofen · Carprofen · Dexibuprofen · Dexketoprofen · Fenbufen · Fenoprofen · Flunoxaprofen · Flurbiprofen · Ibuproxam · Indoprofen^† · Ketoprofen · Ketorolac · Loxoprofen · Miroprofen · Naproxen · Oxaprozin · Pirprofen · Suprofen · Tarenflurbil · Tiaprofenic acid
N-Arylanthranilic acids (fenamic acids)	Mefenamic acid · Flufenamic acid · Meclofenamic acid · Tolfenamic acid
Pyrazolidine derivatives	Phenylbutazone · Ampyrone · Azapropazone · Clofezone · Kebuzone · Metamizole^† · Mofebutazone · Oxyphenbutazone · Phenazone · Sulfinpyrazone
Oxicams	Piroxicam · Droxicam · Lornoxicam · Meloxicam · Tenoxicam
COX -2 inhibitors	Celecoxib · Deracoxib^‡ · Etoricoxib · Firocoxib^‡ · Lumiracoxib^† · Parecoxib · Rofecoxib^† · Valdecoxib^†
Sulphonanilides	Nimesulide
Topically used products	Bendazac · Diclofenac · Etofenamate · Felbinac · Flurbiprofen · Ibuprofen · Indometacin · Ketoprofen · Naproxen · Piroxicam · Suprofen
Others	Fluproquazone · COX-inhibiting nitric oxide donator
Items listed in bold indicate initially developed compounds of specific groups. ^†Withdrawn drugs. ^‡Veterinary use medications.

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Topical
ATC code	M02AA08 (WHO)
Legal status
Legal status	UK: P (Pharmacy medicines)
Identifiers
IUPAC name biphenyl-4-ylacetic acid
CAS Number	5728-52-9
PubChem CID	3332
DrugBank	DB07477^Y
ChemSpider	3215^Y
UNII	94WNJ5U8L7
KEGG	D01675^Y
ChEBI	CHEBI:31597^Y
ChEMBL	ChEMBL413965^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₄H₁₂O₂
Molar mass	212.244 g/mol
3D model (JSmol)	Interactive image
SMILES O=C(O)Cc1ccc(cc1)c2ccccc2
InChI InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)^Y Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N^Y
(verify)

Felbinac: Difference between revisions

Latest revision as of 18:30, 10 April 2015

Overview

References

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