Gepefrine: Difference between revisions

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Gepefrine
Clinical data
ATC code	C01CA15 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (±)-3-(2-aminopropyl)phenol;
CAS Number	1075-61-2 ; 18840-47-6 ((S)-form); 60763-48-6 (tartrate);
PubChem CID	219105;
ChemSpider	189921 ;
UNII	V51RRX51VH;
KEGG	D07150 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C9H13NO
Molar mass	151.206 g/mol
3D model (JSmol)	Interactive image;
	SMILES OC1=CC(C[C@H](C)N)=CC=C1;
	InChI InChI=1S/C9H13NO/c1-7(10)5-8-3-2-4-9(11)6-8/h2-4,6-7,11H,5,10H2,1H3/t7-/m0/s1 ; Key:WTDGMHYYGNJEKQ-ZETCQYMHSA-N ;
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VisualWikitext

Latest revision as of 15:13, 13 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Gepefrine (INN; trade names Pressionorm and Wintonin), also known as 3-hydroxyamphetamine, meta-hydroxyamphetamine,^[1] and α-methyl-meta-tyramine, is an antihypotensive or sympathomimetic agent of the amphetamine family that is marketed in certain European countries.^[2]^[3]

It is a known metabolite of amphetamine in rats.^[1]

References

↑ ^1.0 ^1.1 Jonsson J (October 1977). "Identification of metahydroxyamphetamine as a metabolite of amphetamine in the rat". Research Communications in Chemical Pathology and Pharmacology. 18 (2): 189–99. PMID 918344.
↑ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 487. ISBN 978-3-88763-075-1. Retrieved 24 April 2012.
↑ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 127. ISBN 978-0-412-46630-4. Retrieved 24 April 2012.

Template:Phenethylamines

[pmid918344-1] 1.0 ^1.1 Jonsson J (October 1977). "Identification of metahydroxyamphetamine as a metabolite of amphetamine in the rat". Research Communications in Chemical Pathology and Pharmacology. 18 (2): 189–99. PMID 918344.

[Index_Nominum_2000:_International_Drug_Directory-2] Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 487. ISBN 978-3-88763-075-1. Retrieved 24 April 2012.

[Macdonald1997-3] F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 127. ISBN 978-0-412-46630-4. Retrieved 24 April 2012.

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
 {{Drugbox
-| IUPAC_name        = 3-(2-aminopropyl)phenol
+| Watchedfields = changed
-| image             = gepefrine.png
+| verifiedrevid = 447926897
-| CAS_number        =
+| IUPAC_name = (±)-3-(2-aminopropyl)phenol
-| ATC_prefix        = C01
+| image =Gepefrine.png
-| ATC_suffix        = CA15
+| imagename = Gepefrine
-| PubChem           = 102551
-| DrugBank          =
+<!--Clinical data-->
-| C=9|H=13|N=1|O=1
+| tradename =
-| molecular_weight  = 151.206 g/mol
+| pregnancy_category =
-| bioavailability   =
+| legal_status = Rx-only
-| protein_bound     =
+| routes_of_administration =
-| metabolism        =
-| elimination_half-life =
+<!--Pharmacokinetic data-->
-| excretion         =
+| bioavailability =
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
+| metabolism =
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
+| elimination_half-life =
-| pregnancy_category=
+| excretion =
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
+<!--Identifiers-->
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
+| CAS_number_Ref = {{cascite|correct|??}}
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
+| CAS_number = 1075-61-2
-| legal_status      =
+| CAS_supplemental = <br />18840-47-6 ((''S'')-form)<br />60763-48-6 ([[tartrate]])
-| routes_of_administration =
+| ATC_prefix = C01
+| ATC_suffix = CA15
+| PubChem = 219105
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 189921
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = V51RRX51VH
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D07150
+<!--Chemical data-->
+| C = 9 | H = 13 | N = 1 | O = 1
+| molecular_weight = 151.206 g/mol
+| smiles = OC1=CC(C[C@H](C)N)=CC=C1
+| InChI = 1/C9H13NO/c1-7(10)5-8-3-2-4-9(11)6-8/h2-4,6-7,11H,5,10H2,1H3/t7-/m0/s1
+| InChIKey = WTDGMHYYGNJEKQ-ZETCQYMHBW
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C9H13NO/c1-7(10)5-8-3-2-4-9(11)6-8/h2-4,6-7,11H,5,10H2,1H3/t7-/m0/s1
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = WTDGMHYYGNJEKQ-ZETCQYMHSA-N
 }}
-__NOTOC__
+__Notoc__
+{{SI}}
 {{CMG}}
+==Overview==
-{{Editor Join}}
+'''Gepefrine''' ([[International Nonproprietary Name|INN]]; trade names '''Pressionorm''' and '''Wintonin'''), also known as '''3-hydroxyamphetamine''', '''''meta''-hydroxyamphetamine''',<ref name="pmid918344">{{cite journal | author = Jonsson J | title = Identification of metahydroxyamphetamine as a metabolite of amphetamine in the rat | journal = Research Communications in Chemical Pathology and Pharmacology | volume = 18 | issue = 2 | pages = 189–99 |date=October 1977 | pmid = 918344 | doi = | url = }}</ref> and '''α-methyl-''meta''-tyramine''', is an [[antihypotensive]] or [[sympathomimetic]] agent of the [[amphetamine]] family that is marketed in certain [[Europe]]an countries.<ref name="Index Nominum 2000: International Drug Directory">{{cite book | title = Index Nominum 2000: International Drug Directory | url = http://books.google.com/books?id=5GpcTQD_L2oC&pg=PA487 | accessdate = 24 April 2012 | year = 2000 | publisher = Taylor & Francis US | isbn = 978-3-88763-075-1 | page = 487}}</ref><ref name="Macdonald1997">{{cite book | author = F.. Macdonald | title = Dictionary of Pharmacological Agents | url = http://books.google.com/books?id=DeX7jgInYFMC&pg=PA127 | accessdate = 24 April 2012 | year = 1997 | publisher = CRC Press | isbn = 978-0-412-46630-4 | page = 127}}</ref>
+It is a known [[metabolite]] of [[amphetamine]] in rats.<ref name="pmid918344" />
-==[[Gepefrine (patient information)|For patient information, click here]]==
+== See also ==
+* [[Norfenfluramine]]
+* [[Metaraminol]]
-==Overview==
-'''Gepefrine''' is a cardiac stimulant.
+== References ==
+{{Reflist|2}}
-{{Cardiac stimulants excluding cardiac glycosides}}
+{{Phenethylamines}}
 [[Category:Phenols]]
-[[Category:Phenethylamines]]
+[[Category:Sympathomimetics]]
-[[Category:Drugs]]
+[[Category:Drug]]
-{{WikiDoc Help Menu}}
-{{WikiDoc Sources}}

Clinical data

ATC code	C01CA15 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (±)-3-(2-aminopropyl)phenol
CAS Number	1075-61-2^Y 18840-47-6 ((S)-form) 60763-48-6 (tartrate)
PubChem CID	219105
ChemSpider	189921^Y
UNII	V51RRX51VH
KEGG	D07150^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₉H₁₃NO
Molar mass	151.206 g/mol
3D model (JSmol)	Interactive image
SMILES OC1=CC(C[C@H](C)N)=CC=C1
InChI InChI=1S/C9H13NO/c1-7(10)5-8-3-2-4-9(11)6-8/h2-4,6-7,11H,5,10H2,1H3/t7-/m0/s1^Y Key:WTDGMHYYGNJEKQ-ZETCQYMHSA-N^Y
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Gepefrine: Difference between revisions

Latest revision as of 15:13, 13 April 2015

Overview

See also

References

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