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{{drugbox |
<div style="float: right;">
| IUPAC_name = [4-amino-4-oxo-3,3-di(phenyl)butyl]-methyl-di(propan-2-yl)azanium
[[File:Isopropamide.png|thumb|none|400px|This image is provided by the National Library of Medicine.]]</div>
| image = Isopropamide.png
__NOTOC__
| CAS_number = 71-81-8
{{SI}}
| ATC_prefix =
{{CMG}}
| ATC_suffix =
| PubChem = 3775
| DrugBank =
| C=23 | H=33 | N=2 | O=1 <sup>+</sup>
| molecular_weight = 353.52092 g/mol
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| pregnancy_AU =  <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US =  <!-- A / B / C / D / X -->
| pregnancy_category = 
| legal_AU =      <!-- Unscheduled / S2 / S3 / S4  / S8 -->
| legal_UK =      <!-- GSL / P / POM / CD -->
| legal_US = Rx-only, Unscheduled
| legal_status =
| routes_of_administration = Oral
}}
'''Isopropamide''' is a long-acting [[anticholinergic]] [[drug]]. It is used in the treatment of [[peptic ulcer]] and other [[gastrointestinal]] disorders marked by hyperacidity and hypermotility. Chemically, it contains a quaternary ammonium group. It was discovered at [[Janssen Pharmaceutica]] in [[1954]].


==Overview==
'''Isopropamide''' is a long-acting [[anticholinergic]] [[drug]]. It is used in the treatment of [[peptic ulcer]]s and other [[gastrointestinal]] disorders involving hyperacidity (gastrointestinal [[acidosis]]) and hypermotility. Chemically, it contains a [[quaternary ammonium]] group. It is most often provided as an [[iodide]] salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
==References==
==References==
* Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
{{reflist|2}}
* Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.


{{pharm-stub}}
[[Category:Anticholinergics]]
 
[[Category:Quaternary ammonium compounds]]
[[Category:Drugs]]
[[Category:Amides]]
{{WikiDoc Sources}}
[[Category:Drug]]

Latest revision as of 19:45, 7 April 2015

This image is provided by the National Library of Medicine.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Isopropamide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.

References

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