Carbocisteine: Difference between revisions

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Latest revision as of 16:15, 8 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Carbocisteine is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.

Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.^[1]

Trade names

Fluidol, Humotusin: Romania
Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam^[2]
Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.
Mucoral: Portugal
Mucosol: Egypt
Solmux, Loviscol: Philippines

References

↑ Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in Ullmann's Encyclopedia of Industrial Chemistry, 2007, Wiley-VCH, Weinheim. doi:10.1002/14356007.a02_057.pub2
↑ http://www.drugs.com/international/rhinathiol.html

Template:Cough and cold preparations

[1] Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in Ullmann's Encyclopedia of Industrial Chemistry, 2007, Wiley-VCH, Weinheim. doi:10.1002/14356007.a02_057.pub2

[2] ttp://www.drugs.com/international/rhinathiol.html

[1]

[2]

@@ Line 1: / Line 1: @@
-{{drugbox
+: [[File:Carbocystiene Wiki Str.png|right|300px]]
-| IUPAC_name        = 2-amino-3-(carboxymethylsulfanyl)propanoic acid
+__NOTOC__
-| image             = carbocisteine.png
+{{SI}}
-| CAS_number        =
+{{CMG}}
-| ATC_prefix        = R05
+==Overview==
-| ATC_suffix        = CB03
+'''Carbocisteine''' is a [[mucolytic]] that reduces the viscosity of sputum and so can be used to help relieve the symptoms of [[chronic obstructive pulmonary disorder]] (COPD) and [[bronchiectasis]] by allowing the sufferer to bring up [[sputum]] more easily. Carbocisteine should not be used with [[antitussive]]s (cough suppressants) or medicines that dry up bronchial secretions.
-| PubChem           = 1080
-| DrugBank          =
-| C=5|H=9|N=1|O=4|S=1
-| molecular_weight  = 179.195 g/mol
-| bioavailability   =
-| protein_bound     =
-| metabolism        =
-| elimination_half-life =
-| excretion         =
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
-| pregnancy_category=
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| legal_status      =
-| routes_of_administration =
-}}
-'''Carbocisteine''' is a [[mucolytic]] that can be used to help relieve the symptoms of Chronic Obstructive Pulmonary Disorder [[COPD]] and [[bronchiectasis]] by allowing the sufferer to bring up [[sputum]] more easily.
-{{pharmacology-stub}}
+Carbocisteine is produced by [[alkylation]] of [[cysteine]] with [[chloroacetic acid]].<ref>Karlheinz Drauz, Ian Grayson, Axel Kleemann, Hans-Peter Krimmer, Wolfgang Leuchtenberger, Christoph Weckbecker “Amino Acids” in ''Ullmann's Encyclopedia of Industrial Chemistry'', 2007, Wiley-VCH, Weinheim. {{DOI|10.1002/14356007.a02_057.pub2}}</ref>
+==Trade names==
+*Fluidol, Humotusin: Romania
+*Rhinathiol: Bulgaria, Congo, Hong Kong, Hungary, Latvia, Lithuania, Malaysia, Oman, Romania, Singapore, South Korea, Switzerland, Taiwan, Thailand, Tunisia, and Vietnam<ref>http://www.drugs.com/international/rhinathiol.html</ref>
+*Mucodyne: United Kingdom, India, Ireland, Japan, Netherlands, Serbia.
+*Mucoral: Portugal
+*Mucosol: Egypt
+*Solmux, Loviscol: Philippines
+==References==
+{{reflist|2}}
 {{Cough and cold preparations}}
-[[Category:Antitussives]]
+[[Category:Drug]]
-[[Category:Amino acids]]
+[[Category:Dicarboxylic acids]]
+[[Category:Expectorants]]
 [[Category:Thioethers]]
+[[Category:Amino acid derivatives]]

Carbocisteine: Difference between revisions

Latest revision as of 16:15, 8 April 2015

Overview

Trade names

References

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