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{{CMG}}; '''Associate Editor-In-Chief:''' Priyantha Ranaweera [mailto:pranawee@bidmc.harvard.edu];  
{{CMG}}; '''Associate Editor-In-Chief:''' Priyantha Ranaweera [mailto:pranawee@bidmc.harvard.edu];  


'''''Key Words and Synonyms:''''' PCI guidewire, angioplasty guidewire, coronary guidewire, steerable wire, steerable guidewire
'''''Key Words and Synonyms:''''' PCI guidewire; angioplasty guidewire; coronary guidewire; steerable wire; steerable guidewire.


==[[Guidewire overview|Overview]]==
==Overview==
Angioplasty guidewires are small, soft, flexible, lubricated, wires that act as a rail over which equipment such as an angioplasty balloon, a stent, or an intravascular ultrasound device can be delivered over into the coronary artery.  Angioplasty guide wires were introduced in 1982 by doctors Simpson and Roberts. The introduction of coronary guidewires was a major advance as it allowed the angioplasty balloon to be a traumatically steered to the proper location.


==[[Guidewire historical perspective|Historical Perspective]]==
==[[Guidewire general techniques|Guidewire Techniques]]==
 
==[[Guidewire desirable performance characteristics|Desirable Performance Characteristics of Coronary Guidewires]]==


==[[Guidewire complications|Guidewire Complications]]==
==[[Guidewire complications|Guidewire Complications]]==


==[[Guidewire torquer device|Steering the Guidewire]]==
==[[Guidewire desirable performance characteristics|Desirable Performance Characteristics of Coronary Guidewires]]==


==Guidewire Design Features==
==Guidewire Design Features==
A guidewrie has three main components - a Core, a Tip and a Lubricous Coating.  
A guidewrie has three main components - a core, a tip and a lubricous Coating.  


[[Image:Components_of_a_guide_wire.jpg]]
[[Image:Components_of_a_guide_wire.jpg]]
Line 23: Line 22:
Figure : Components of a guide wire (courtesy : Abbott vascular inc)
Figure : Components of a guide wire (courtesy : Abbott vascular inc)


[[Guidewire core]] | [[Guidewire coatings]] | [[Guidewire tip]]
[[Guidewire Core]] | [[Guidewire Coatings]] | [[Guidewire Tip]]


[[Guidewire core diameters]] | [[Guidewire tip diameters]] | [[Guidewire lengths]]
[[Guidewire Core Diameters]] | Guidewire Wisdom | [[Guidewire Tip Diameters]] | [[Guidewire Lengths]]


==[[List of Guidewires by Manufacturer]]==
==Guidewires Classified Based Upon Support (Steerability and Trackability)==


===[[Guidewires commonly used|Commonly Used Guidewires]]===
===Soft Guidewires===
[[Guidewire Asahi soft| Asahi Soft Guidewire]] | Hi-torque Balance


===Moderate Support Guidewires===
[[Guidewire wisper wire|Wisper Wire]] | [[Guidewire High torque balance middle weight|High Torque Balance Middle Weight]]


=====extra support=====
===Extra Support Guidewires===
*ChoICE PT extra support
[[Guidewire choice PT extra support|Choice PT Extra Support]] | PT Graphix Intermediate | Stabilizer | [[Guidewire hi-torque balance heavy weight|Hi-Torque Balance Heavy Weight]]
*PT Graphix intermediate
*Stabilizer
*Hi-torque balance heavy weight


=====Super extra support=====
===Super Extra Support Guidewires===
*Iron man
[[Guidewire iron man|Iron Man]] | [[guidewire asahi grand slam|Asahi Grand Slam]]
*Asahi grand slam


2. Crossing profile
==Guidewires Classified By Crossing Profile==


2.1 Simple lesions
===Complex lesions and lesions in very tortuous vessels===
[[Guidewire prowater|Prowater]] | [[Guidewire Choice PT|Choice PT]] | PT Graphix Intermediate


2.2 Complex lesions and lesions in very tortuous vessels
===Guidewires Used to Cross Chronic Total Occlusions===
*Prowater
Wires to be used in escalating order of aggressiveness:
*ChoICE PT  
====First Choice====
*PT graphix intermediate
'''Non-hydrophilic''' or '''hydrophobic''' wires with an '''intermediate stiffness''' are a good first choice as they have a better tactile response, are less likely to lead to a subintimal position than a hydrophilic wire, and may have an additional advantage in their ability to cross the proximal cap of the occlusion. Choices in this class include the [[Miracle Bros]] 3 and the [[Asahi intermediate wires]].
====Second Choice====
'''Hydrophilic''' wires may track better after the proximal cap of the occlusion has been crossed.  Hydrophilic/coated wires have better maneuverability in [[tortuosity|tortuous]] or [[calcification|calcified]] vessels.  '''Intermediate stiffness hydrophilic wire''' choices include the [[Choice PT XS (Extra Support)]], the [[Pilot 50]], the [[Pilot 100]] or the [[PT Graphix intermediate wire]].


2.3 Chronic total occlusions
====Third Choice====
*Cross it series
'''Stiff non-hydrophilic wires''': The [[Miracle Bros]] 6, 9 and 12, [[Cross-IT]], [[Confienza]], [[Persuader]]
*Miracle bro series
====Fourth Choice====
*Shinobi
'''Stiff and hydrophilic (most aggressive)''': [[Pilot 200]] and [[Shinobi]]
*Confianza


3. Device delivery wires
==Device Delivery Guidewires==
*Stablizier
Guidewire wiggle wire- The wiggle wire has a niche role in delivering stents and balloons into areas with poor transmission of proximal push.  The wiggle wire works by shifting the direction of the pushing forces thus "stepping over" the obstacle.
*Wiggle


===[[COMMONLY USED GUIDE WIRES]]===
==Peripheral Arterial Guidewires==
* Spartacore - The Spartacore is a peripheral arterial guidewire.
* Guidewire V 18


===ASAHI SOFT / LIGHT GUIDE WIRE===
==Guidewire Tourquing Device==
A torquing device is a tool interventional cardiologists use to torque a coronary guidewire and to maintain the tension on the guidewire to preserve the torque and the direction the guidewire.  There is a gradual inadvertent “unwinding” of torque when the human fingers are used to steer a coronary guidewire, and this unwinding can be effectively prevented by this tool.


 
==[[List of Guidewires by Manufacturer]]==
[[Image:Asahi_soft.jpg]]
 
*Hydrophobic Coating
*Soft tip
*Flexible body
*Support to deliver most interventional devices
*Tip load: 0.5 g
*Radiopaque length: 3 cm
*Outside diameter: 0.014"
*Total length: 180 cm – 300 cm
 
 
===ASAHI PROWATER AND PROWATER FLEX===
 
Relatively safe guide wire with moderate support.
 
[[Image:Asahi_prowater_and_prowater_flex.jpg]]
 
Source : http://www.abbottvascular.com/
 
*Has a hybrid Coating: Soft hydrophobic tip & hydrophilic working coils. Hydrophilic coating maximizes lubricity to navigate anatomy and hydrophobic coating designed to enhance tactile feel.
*Uses  “TruTorq” technology - a design that fuses stainless steel to platinum spring coils via a single-joint. (claimed to afford the improved torque response and steerability seen with this wire.)
*Tip load: 0.8 g
*Radiopaque length: 3 cm
*Outside diameter: 0.014"
*Total length: 180 cm, 300 cm
 
===ACS HI TORQUE BALANCED MIDDLE WEIGHT (BMW)===
 
===ACS HIGH TORQE BALANCE MIDDLE WEIGHT (BMW) UNIVERSAL===
 
Shaping ribbon provides reasonable provision for shape retention & tip softness
 
Intermediate coils at the tip maintain .014" diameter for smooth device delivery
 
*Hydrophobic or Hydrophilic coating for tracking
 
 
[[Image:Asahi_Tru_Torq_Steel.jpg]]
 
====HI-TORQUE BALANCE MIDDLEWEIGHT UNIVERSAL====
 
 
[[Image:BMW_universal.jpg]]
 
 
Durasteel shaping ribbon material provides added durability and shape retention
 
Intermediate section has both a hydrophilic coating and a polymer cover
 
===PT GRAPHIX INTERMEDIATE===
 
Figure  Source http://www.bostonscientific.com
 
===ChoICE PT ===
 
Excellent in crossing moderately difficult lesions and negotiating tortuous lesions.
 
[[Image:CPT.jpg]]
 
Crossing guide wire with light rail support.
 
Unibody stainless steel
Polymer tip
Hydrophilic ICE coating
Radioopaque length 35 cm
Outside diameter 0.014”
Available lengths182cm, 300 cm
Compatible with magnet Exchange Device
 
===ChoICE PT Extra support===
 
Crossing guide wire with extra rail support
 
Figure CPT XS jpg
 
Unibody stainless steel
Polymer tip
Hydrophilic ICE coating
Radioopaque length 35 cm
Outside diameter 0.014”
Available lengths 182cm, 300 cm
Compatible with Magnet Exchange Device
 
===ChoICE Floppy guide wire===
 
Relatively atraumatic guide wire with light rail support.
 
Figure Choice jpg
 
Unibody stainless steel
Spring tip, polymer sleeve
ICE hydrophilic coating
 
Radioopaque length 3 cm
Outside diameter 0.014”
Available lengths 182cm, 300 cm
Compatible with Magnet Exchange Device
 
===ChoICE Extra support===
 
Delivery support wire with extra rail support.
 
 
[[Image:CPT_XS.jpg]]
 
=====BASIC CONSTRUCTION=====
 
Unibody stainless steel core
Spring tip, Polymer sleeve
ICE hydrophilic coating
Radioopaque length 3 cm
Outside diameter 0.014”
Available lengths 182cm, 300 cm
Compatible with Magnet Exchange Device
 
====WHISPER====
[[Image:Whisper.jpg]]
 
Durasteel™ Core-to-tip designed to improve steering, durable shape retention and tactile feedback
 
Full Polymer cover with Hydrophilic coating intended for deliverability and smooth lesion access
 
Responsease™ “transitionless” core grind designed to provide improved tracking and better torque response
 
Tip coils designed to provide softer, shapeable tip and also improve tactile feedback
 
 
 
====STABILIZER EXTRA SUPPORT====
 
==== WIZDOM====
 
:
 
:
 
 
=====WIGGLE WIRE=====
 
This wire has a niche role in delivering stents and balloons in to areas with poor transmission of proximal push. It works by shifting the direction of the pushing forces thus "stepping over" the :obstacle".
 
 
 
=====IRON MAN GUIDEWIRE=====
 
Stiff wire with poor steerability. Its rigidness is used to straighten vessel segements and allow better transmission of forces pushing balloons or stents.  This property comes from the tendency of the wire to retain its shape rather than conform to the contours of the vessel. This feature makes “cheese cutter” effects on the vascular intima at their bends. This some times is demonstrated angiographically by a “pleating artifact” and in extreme situations could lead to a transient “no-reflow” state. ( Figure) Though this wire will allow transmit more force to the balloon or the stent, it could actually make device delivery more difficult in tortuous vessels.
 
===GUIDE WIRES PRIMARILY USED FOR CHRONIC TOTAL OCCLUSIONS===
 
===CROSS IT GUIDE WIRES===
 
1. CROSS IT XT 100
 
Cross it 100 xt
 
Figure source:  http://www.abbottvascular.com
 
 
Tapered tip coil from 0.014" to 0.010" at distal 3 cm
Hydrocoat hydrophilic coating of distal 30 cm
 
 
:
 
2. Cross it 200 XT
 
 
Cross it 200 xt
 
 
 
 
 
3. Cross it 300 XT
 
Cross it 300 xt
 
 
 
===PILOT WIRES===
 
===Pilot 50, 150, 200===
 
 
 
 
Figure
:
 
====PERSUADER ====
 
These wires are mainly used to cross challenging chronic total occlusions
 
Core to tip family used mainly for CTOs
 
 
Figures source    http://www.medtronic.com
 
=====PERSUADER 3====
 
Persuader 3jpg
 
====PERSUADER 6====
 
Persuader 6jpg
 
 
====PERSUADER 9====
Persuader 9jpg
 
 
 
 
===ASAHI MIRACLE BRO===
 
These wires are mainly used to cross challenging chronic total occlusions
Core to tip guidewires
 
 
===ASAHI MIRACLE BRO 3===
 
1. Asahi miraclebros 3.JPG
 
Tip load: 3 g
Radiopaque length: 11 cm
Outside diameter: 0.014"
Total length: 180 cm
 
2. Asahi Miraclebro 4.5
 
Asahi miraclebros 45.JPG
 
 
Tip load: 4.5 g
Radiopaque length: 11 cm
Outside diameter: 0.014"
Total length: 180 cm
 
3. Asahi Miraclebro 6
 
Asahi miraclebros 6.JPG
 
Tip load: 6 g
Radiopaque length: 11 cm
Outside diameter: 0.014"
Total length: 180 cm
 
4. Asahi Miraclebro 12
 
Asahi miraclebros 12.JPG
 
Tip load: 12 g
Radiopaque length: 11 cm
Outside diameter: 0.014"
Total length: 180 cm
 
=====STEEL CORE=====
 
===ZINGER GUIDEWIRE===
 
===COUGAR GUIDEWIRE===
 
===THUNDER GUIDEWIRE===
 
=====ASAHI GRAND SLAM=====
 
The tip is very flexible, hence less traumatic, but provides considerable support.
Tip load: 0.7 g
Radiopaque length: 3 cm
Outside diameter: 0.014"
Total length: 180 cm, 300 cm
 
 
Asahi grand slam jpg.
 
=====SPARTACORE=====
 
This wire is mainly used in peripheral interventions.
 
 
 
=====V 18=====
 
This is a .018” wire mainly used in the peripheral interventions. It is a stiff wire with excellent torque control, tendency to prolapse and perforation.
 
====STEERABLE GUIDE WIRES====
 
====Cordis ATW™ All Track Wire====
FIG CORDIS STEERABLE GUIDE WIRE
 
Moderate Support
General Purpose
Precision Control from Hand to Tip
Precise steerability for lesion access
Enhanced flexibility for tracking in tortuous vessels
Highly lubricious, durable platform for smooth delivery of multiple devices
The ATWTM Guidewire atraumatic floppy tip and integrated FLEX-JOINTTM Bond combine for distal flexibility and atraumatic vessel tracking
 
====TIPS IN CROSSING A LESION====
 
1. Use a bend at the tip of the wire which is roughly the length of the diameter of the vessel proximal to the lesion.
2. If a wire repeatedly fails to cross a lesion,
a. Adjust the guide,
b. Use a balloon, transit, ultrafuse or twin pass catheter to direct the wire
c. modify the bend at the tip.
d. change the wire ( check the tip of the wire for evidence of wear and tear)
3. A wire in a balloon or a catheter ( ultrafuse, transit or exchelon) may help guide the wire through the lesion
 
 
==SAFETY TIPS==
 
1. Get used to a few wires to suit most situations
2. Always use the least traumatic wire for the lesion, >90% lesions could be crossed with standard “work horse” wires
3. Until familiar and comfortable, do not rush in to wires which are mote likely to perforate.
4. Avoid bending or buckling the wire
5. Never push a wire, let it find its “track” with
6. A ventricular premature beat could be a suggestion that the wire is off track, withdraw the wire immediately and redirect it.
7. Check every fluro and cine loop for evidence for perforation, embolization and dissection. If the picture quality is poor, then do not hesitate to increase the frame count/radiation to improve it.
8. If there is a suspicion of a perforation, then an emergent Echo should be performed on the table. ( link complications – perforation)




==References==
{{Reflist|2}}


[[Category:Cardiology]]
[[Category:Cardiology]]

Latest revision as of 21:49, 28 January 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyantha Ranaweera [2];

Key Words and Synonyms: PCI guidewire; angioplasty guidewire; coronary guidewire; steerable wire; steerable guidewire.

Overview

Angioplasty guidewires are small, soft, flexible, lubricated, wires that act as a rail over which equipment such as an angioplasty balloon, a stent, or an intravascular ultrasound device can be delivered over into the coronary artery. Angioplasty guide wires were introduced in 1982 by doctors Simpson and Roberts. The introduction of coronary guidewires was a major advance as it allowed the angioplasty balloon to be a traumatically steered to the proper location.

Guidewire Techniques

Guidewire Complications

Desirable Performance Characteristics of Coronary Guidewires

Guidewire Design Features

A guidewrie has three main components - a core, a tip and a lubricous Coating.

Figure : Components of a guide wire (courtesy : Abbott vascular inc)

Guidewire Core | Guidewire Coatings | Guidewire Tip

Guidewire Core Diameters | Guidewire Wisdom | Guidewire Tip Diameters | Guidewire Lengths

Guidewires Classified Based Upon Support (Steerability and Trackability)

Soft Guidewires

Asahi Soft Guidewire | Hi-torque Balance

Moderate Support Guidewires

Wisper Wire | High Torque Balance Middle Weight

Extra Support Guidewires

Choice PT Extra Support | PT Graphix Intermediate | Stabilizer | Hi-Torque Balance Heavy Weight

Super Extra Support Guidewires

Iron Man | Asahi Grand Slam

Guidewires Classified By Crossing Profile

Complex lesions and lesions in very tortuous vessels

Prowater | Choice PT | PT Graphix Intermediate

Guidewires Used to Cross Chronic Total Occlusions

Wires to be used in escalating order of aggressiveness:

First Choice

Non-hydrophilic or hydrophobic wires with an intermediate stiffness are a good first choice as they have a better tactile response, are less likely to lead to a subintimal position than a hydrophilic wire, and may have an additional advantage in their ability to cross the proximal cap of the occlusion. Choices in this class include the Miracle Bros 3 and the Asahi intermediate wires.

Second Choice

Hydrophilic wires may track better after the proximal cap of the occlusion has been crossed. Hydrophilic/coated wires have better maneuverability in tortuous or calcified vessels. Intermediate stiffness hydrophilic wire choices include the Choice PT XS (Extra Support), the Pilot 50, the Pilot 100 or the PT Graphix intermediate wire.

Third Choice

Stiff non-hydrophilic wires: The Miracle Bros 6, 9 and 12, Cross-IT, Confienza, Persuader

Fourth Choice

Stiff and hydrophilic (most aggressive): Pilot 200 and Shinobi

Device Delivery Guidewires

Guidewire wiggle wire- The wiggle wire has a niche role in delivering stents and balloons into areas with poor transmission of proximal push. The wiggle wire works by shifting the direction of the pushing forces thus "stepping over" the obstacle.

Peripheral Arterial Guidewires

  • Spartacore - The Spartacore is a peripheral arterial guidewire.
  • Guidewire V 18

Guidewire Tourquing Device

A torquing device is a tool interventional cardiologists use to torque a coronary guidewire and to maintain the tension on the guidewire to preserve the torque and the direction the guidewire. There is a gradual inadvertent “unwinding” of torque when the human fingers are used to steer a coronary guidewire, and this unwinding can be effectively prevented by this tool.

List of Guidewires by Manufacturer


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