Extramammary Paget's disease: Difference between revisions

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Latest revision as of 23:20, 26 November 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]Simrat Sarai, M.D. [3] Synonyms and keywords: Extramammary Paget disease; EMPD; extramammary Paget's disease; empd

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Extramammary Paget's disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

Related chapters

Paget's disease of the breast

Template:Epithelial neoplasms

Template:WikiDoc Sources

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-'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
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+{{Extramammary Paget's disease}}
+{{CMG}}; {{AE}} {{KS}}{{Simrat}}
+{{SK}} Extramammary Paget disease; EMPD; extramammary Paget's disease; empd
+==[[Extramammary Paget's disease overview|Overview]]==
+==[[Extramammary Paget's disease historical perspective|Historical Perspective]]==
+==[[Extramammary Paget's disease classification|Classification]]==
-{{Infobox_Disease
+==[[Extramammary Paget's disease pathophysiology|Pathophysiology]]==
- | Name           = {{PAGENAME}}
+==[[Extramammary Paget's disease causes|Causes]]==
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+==[[Extramammary Paget's disease differential diagnosis|Differentiating Extramammary Paget's disease from other Diseases]]==
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+==[[Extramammary Paget's disease epidemiology and demographics|Epidemiology and Demographics]]==
- | DiseasesDB     =
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- | ICDO           = M8542/3
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+==[[Extramammary Paget's disease risk factors|Risk Factors]]==
-==Overview==
+==[[Extramammary Paget's disease screening|Screening]]==
-'''Extramammary Paget’s disease''' ('''EMPD'''), also '''Extramammary Paget disease''', is a usually non-invasive [[adenocarcinoma]] of the [[skin]] outside of the [[mammary gland]]  and includes ''Paget's disease of the [[vulva]]'' and ''Paget's disease of the [[penis]]''. The origin of the neoplastic cells could be [[apocrine gland]]s or epithelial [[stem cells]]. Skin areas rich in apocrine glands such as the genital region are typical sites of EMPD.
+==[[Extramammary Paget's disease natural history|Natural History, Complications and Prognosis]]==
-==History==
+==Diagnosis==
-[[James Paget]] had described Paget disease of the nipple in 1874. Radcliffe Crocker reported the first case of EMPD in 1889 when he described a patient with a skin lesion affecting the penis and scrotum the findings of which were identical to those described by Paget. EMPD is found in a number of locations where apocrine glands are common.
+[[Extramammary Paget's disease history and symptoms|History and Symptoms]] | [[Extramammary Paget's disease physical examination|Physical Examination]] | [[Extramammary Paget's disease chest x ray|Chest X Ray]] | [[Extramammary Paget's disease CT|CT]] | [[Extramammary Paget's disease MRI|MRI]] | [[Extramammary Paget's disease other imaging findings|Other Imaging Findings]] | [[Extramammary Paget's disease other diagnostic studies|Other Diagnostic Studies]]
-==Types==
+==Treatment==
-'''Paget's disease of the vulva''' may be a primary lesion or associated with adenocarcinoma originating from local organs such as  the Bartholin gland, the urethra, or the rectum and thus be secondary. Patients tend to be in the postmenopausal range.
+[[Extramammary Paget's disease medical therapy|Medical Therapy]] | [[Extramammary Paget's disease surgery|Surgery]] | [[Extramammary Paget's disease primary prevention|Primary Prevention]] | [[Extramammary Paget's disease secondary prevention|Secondary Prevention]] | [[Extramammary Paget's disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Extramammary Paget's disease future or investigational therapies|Future or Investigational Therapies]]
-'''Paget's disease of the penis''' may also be primary or secondary and is less common than genital Paget’s disease in women.
+==Case Studies==
-==Primary disease==
+:[[Extramammary Paget's disease case study one|Case #1]]
-It is important to exclude that the lesion is associated with another cancer. Primary disease is usually treated by surgical excision.
-==Signs and symptoms==
+==Related chapters==
-Signs and symptoms are a skin lesion often mistaken as an [[eczema]] that may be [[itch]]y or painful. A [[biopsy]] will establish the diagnosis. The histology of the lesion is the same as for [[Paget's disease of the breast]].
-==See also==
 * [[Paget's disease of the breast]]
 {{Epithelial neoplasms}}
-{{SIB}}
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 [[Category:Disease]]
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 [[Category:Dermatology]]
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