Polymorphous light eruption: Difference between revisions
m Robot: Changing Category:Diseases to Category:Disease |
Tamar Sifri (talk | contribs) No edit summary |
||
| (3 intermediate revisions by one other user not shown) | |||
| Line 14: | Line 14: | ||
}} | }} | ||
__NOTOC__ | __NOTOC__ | ||
{{SI}} | {{SI}} | ||
{{CMG}}; {{AE}} {{KS}} | |||
==Overview== | ==Overview== | ||
| Line 23: | Line 23: | ||
The cause of PLE is not yet understood. It is thought to be due to a type IV delayed-type [[hypersensitivity]] reaction. | The cause of PLE is not yet understood. It is thought to be due to a type IV delayed-type [[hypersensitivity]] reaction. | ||
==Diagnosis== | |||
===Physical Examination=== | |||
====Skin==== | |||
=====Trunk===== | |||
<gallery> | |||
Image:Polymorphic light eruption01.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Polymorphic light eruption02.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Polymorphic light eruption03.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Polymorphic light eruption04.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Polymorphic light eruption06.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Polymorphic light eruption07.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
</gallery> | |||
=====Ear===== | |||
<gallery> | |||
Image:Polymorphic light eruption08.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
Image:Polymorphic light eruption09.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
</gallery> | |||
=====Face===== | |||
<gallery> | |||
Image:Polymorphic light eruption05.jpg|Polymorphic light eruption. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | |||
</gallery> | |||
==Experimental treatments== | ==Experimental treatments== | ||
Latest revision as of 19:35, 30 July 2015
| Polymorphous light eruption | |
| ICD-10 | L56.4 |
|---|---|
| ICD-9 | 692.72 |
| DiseasesDB | 10327 |
| eMedicine | derm/342 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
Overview
Polymorphous light eruption (PLE), or polymorphic light eruption, is a skin complaint caused by sunlight. Symptoms include skin irritations, which may be itchy or painful, and are sometimes confused with hives. These irritations appear upon exposure to sunlight—sometimes as little as 15 minutes of exposure to the sun can bring onset of the condition—and may last from 1 to 7 days. Generally, PLE resolves without treatment; also, PLE irritations generally leave no scar. The cases of this condition are most common between the spring and autumn months in the northern hemisphere.
Typically, 10-20% of the population are affected. It is more common in females than in males. The condition can affect all ethnic groups and research suggests that 20% of patients have a family history of the complaint. Those suffering from PMLE usually do so by age 30.
The cause of PLE is not yet understood. It is thought to be due to a type IV delayed-type hypersensitivity reaction.
Diagnosis
Physical Examination
Skin
Trunk
-
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/5/50/Polymorphic_light_eruption01.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1] -
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/d/d1/Polymorphic_light_eruption02.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1] -
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/0/07/Polymorphic_light_eruption03.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1] -
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/f/fe/Polymorphic_light_eruption04.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1] -
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/8/8f/Polymorphic_light_eruption06.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1] -
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/e/e2/Polymorphic_light_eruption07.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1]
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption01.jpg)
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption02.jpg)
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption03.jpg)
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption04.jpg)
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption06.jpg)
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption07.jpg)
Ear
-
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/6/64/Polymorphic_light_eruption08.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1] -
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/8/8e/Polymorphic_light_eruption09.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1]
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption08.jpg)
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption09.jpg)
Face
-
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/images/f/fe/Polymorphic_light_eruption05.jpg)
Polymorphic light eruption. With permission from Dermatology Atlas.[1]
![Polymorphic light eruption. With permission from Dermatology Atlas.[1]](/index.php/File:Polymorphic_light_eruption05.jpg)
Experimental treatments
As of 2008 a company in Australia named Clinuvel Pharmaceuticals Limited is performing clinical trials with a melanocyte-stimulating hormone named melanotan (which they refer to as CUV1647) for polymorphous light eruption.[2]