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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.
__NOTOC__
{{DiseaseDisorder infobox |
 
  Name          = {{PAGENAME}} |
  ICD10          = {{ICD10|C|56||c|51}}, {{ICD10|D|27||d|10}} |
  ICD9          = {{ICD9|183}}, {{ICD9|220}} |
  ICDO          = varied |
  Image          = ovserca.jpg|
  Caption        = In this TAH-BSO specimen, the right ovary (on the left of the image) has been replaced by a solid serous carcinoma. The contralateral ovarian tumor is grossly cystic and could be termed a "cystadenocarcinoma." The patient had omental metastases and positive peritoneal fluid cytology. This cancer, which was discovered at exploratory laparotomy, apparently developed very rapidly; the patient had a normal pelvic ultrasound exam only 2 months before. <br> (Courtesy of Ed Uthman, MD)|
  OMIM          = |
  OMIM_mult      = |
  MedlinePlus    = 000889 |
  DiseasesDB    = 9418 |
}}
{{Ovarian cancer}}
{{Ovarian cancer}}
{{CMG}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.


==[[Ovarian cancer overivew|Overview]]==
{{CMG}}{{AE}}{{MD}}, {{Hudakarman}}
 
{{SK}} Carcinoma of the ovary, Epithelial ovarian cancer (EOC)
 
==[[Ovarian cancer overview|Overview]]==


==[[Ovarian cancer historical perspective|Historical Perspective]]==
==[[Ovarian cancer historical perspective|Historical Perspective]]==
==[[Ovarian cancer pathophysiology|Pathophysiology]]==


==[[Ovarian cancer classification|Classifications]]==
==[[Ovarian cancer classification|Classifications]]==


==[[Ovarian cancer epidemiology and demographics|Epidemiology and Demographics]]==
==[[Ovarian cancer pathophysiology|Pathophysiology]]==
 
==[[Ovarian cancer risk factors|Risk Factors]]==
 
==[[Ovarian cancer screening|Screening]]==


==[[Ovarian cancer causes|Causes]]==
==[[Ovarian cancer causes|Causes]]==
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==[[Ovarian cancer differential diagnosis|Differentiating Ovarian cancer from other Disorders]]==
==[[Ovarian cancer differential diagnosis|Differentiating Ovarian cancer from other Disorders]]==


==[[Ovarian cancer natural history|Natural History, Complications, and Prognosis]]==
==[[Ovarian cancer epidemiology and demographics|Epidemiology and Demographics]]==


==Staging==
==[[Ovarian cancer risk factors|Risk Factors]]==
Ovarian cancer staging is by the [[FIGO]] staging system and uses information obtained after surgery, which can include a total abdominal [[hysterectomy]], removal of (usually) both ovaries and fallopian tubes, (usually) the [[omentum]],  and pelvic (peritoneal) washings for [[cytology]].  The American Joint Committee on Cancer (AJCC) stage is the same as the FIGO stage.


*Stage I - limited to one or both ovaries
==[[Ovarian cancer screening|Screening]]==
**IA - involves one ovary; [[Capsule (anatomy)|capsule]] intact; no tumor on ovarian surface; no malignant cells in [[ascites]] or peritoneal washings
**IB - involves both ovaries; capsule intact; no tumor on ovarian surface; negative washings
**IC - tumor limited to ovaries with any of the following: capsule ruptured, tumor on ovarian surface, positive washings
*Stage II - pelvic extension or implants
**IIA - extension or implants onto uterus or fallopian tube; negative washings
**IIB - extension or implants onto other pelvic structures; negative washings
**IIC - pelvic extension or implants with positive peritoneal washings
*Stage III - microscopic peritoneal implants outside of the pelvis; or limited to the pelvis with extension to the small bowel or omentum
**IIIA - microscopic peritoneal metastases beyond pelvis
**IIIB - macroscopic peritoneal metastases beyond pelvis less than 2 cm in size
**IIIC - peritoneal metastases beyond pelvis > 2 cm or lymph node metastases
*Stage IV - distant metastases--in the liver, or outside the peritoneal cavity


Para-aortic lymph node metastases are considered regional lymph nodes (Stage IIIC).
==[[Ovarian cancer natural history, complications and prognosis|Natural History, Complications, and Prognosis]]==


==Diagnosis==
==Diagnosis==
[[Ovarian cancer history and symptoms|History and Symptoms]] | [[Ovarian cancer physical examination|Physical Examination]] | [[Ovarian cancer laboratory tests|Laboratory Tests]] | [[Ovarian cancer electrocardiogram | Electrocardiogram]] | [[Ovarian cancer chest x ray|Chest X Ray]] | [[Ovarian cancer MRI|MRI]] | [[Ovarian cancer CT|CT]] | [[Ovarian cancer echocardiography|Echocardiography]] | [[Ovarian cancer other imaging findings|Other Imaging Findings]] | [[Ovarian cancer other diagnostic studies|Other Diagnostic Studies]]
[[Ovarian cancer history and symptoms|History and Symptoms]] | [[Ovarian cancer physical examination|Physical Examination]] | [[Ovarian cancer staging|Staging]] | [[Ovarian cancer laboratory findings|Laboratory Findings]] | [[Ovarian cancer chest x ray|X Rays]] | [[Ovarian cancer CT|CT]] | [[Ovarian cancer MRI|MRI]] | [[Ovarian cancer echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Ovarian cancer other imaging findings|Other Imaging Findings]] | [[Ovarian cancer other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
'''Medical:''' [[Ovarian cancer medical therapy|Medical Therapy]]
[[Ovarian cancer medical therapy|Medical Therapy]] | [[Ovarian cancer surgery|Surgical]] | [[Ovarian cancer primary prevention|Primary Prevention]]  | [[Ovarian cancer secondary prevention|Secondary Prevention]] | [[Ovarian cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Ovarian cancer future or investigational therapies|Future or Investigational Therapies]]


'''Surgical:''' [[Ovarian cancer surgery|Surgery]]
==Case Studies==
 
[[Ovarian cancer case study one|Case #1]]
[[Ovarian cancer primary prevention|Primary Prevention]] | [[Ovarian cancer secondary prevention|Secondary Prevention]] | [[Ovarian cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Ovarian cancer future or investigational therapies|Future or Investigational Therapies]]
 
==References==
{{reflist|2}}


==Related Chapters==
==Related Chapters==
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[[Category:Hereditary cancers]]
[[Category:Hereditary cancers]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gynecology]]
[[Category:Surgery]]

Latest revision as of 14:37, 15 July 2019


Ovarian cancer Microchapters

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Overview

Historical Perspective

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Pathophysiology

Causes of Ovarian cancer

Differentiating Ovarian cancer from other Diseases

Epidemiology & Demographics

Risk Factors

Screening

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms

Physical Examination

Staging

Laboratory Findings

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2], Huda A. Karman, M.D.

Synonyms and keywords: Carcinoma of the ovary, Epithelial ovarian cancer (EOC)

Overview

Historical Perspective

Classifications

Pathophysiology

Causes

Differentiating Ovarian cancer from other Disorders

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Staging | Laboratory Findings | X Rays | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgical | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters


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