PCI complications: distal embolization: Difference between revisions

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'''Editor(s)-In-Chief:''' [[ C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org]; Alexandra Almonacid M.D. [mailto:aalmonacid@partners.org]; Jeffrey J. Popma M.D. [mailto:jpopma@partners.org]
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{{CMG}}; {{AE}} {{HP}}, {{Sapan}}


==Definition==
==Overview==
[[Distal]] [[embolization]] during [[percutaneous coronary intervention]] is defined as either partial or complete occlusion of an instrumented major epicardial [[coronary artery]] or a branch due to downstream movement of either [[thrombus]], [[atheroma]], fracture of the [[distal]] tip of a [[coronary guidewire]], an undeployed stent or air.<ref name="pmid8187116">{{cite journal |author=Ishizaka N, Issiki T, Saeki F, Furuta Y, Ikari Y, Yamaguchi T |title=Predictors of myocardial infarction after distal embolization of coronary vessels with percutaneous transluminal coronary angioplasty. Experience of 21 consecutive patients with distal embolization |journal=[[Cardiology]] |volume=84 |issue=4-5 |pages=298–304 |year=1994 |pmid=8187116 |doi= |url= |accessdate=2011-12-28}}</ref> It is manifested clinically as either [[chest pain]], [[ST segment elevation]], [[no reflow]] during the procedure and / or a rise in [[biomarkers]] of [[myonecrosis]] ([[CK-MB]] or [[troponin]]) following the [[PCI]].


Clinical distal embolization during PCI is defined as the evidence of peri-procedural myonecrosis, while angiographic distal embolization is known as the migration of a filling defect or thrombus to distally occlude the target vessel or one of its branches (1).
==Causes==
*[[Thrombus]] (from a thrombotic culprit lesion or a [[coronary guidewire]] or other equipment in the [[coronary artery]])
*[[Atheroma]]
*An undeployed stent
*Fracture of the [[distal]] tip of a [[coronary guidewire]]
*Air bubbles from manifold injections


==Incidence==
==Epidemiology and Demographics==
Distal embolization occurs in approximately 10% of patients with an [[acute myocardial infarction]] undergoing PCI. Embolic complications occur more often in patients with [[acute MI]] and in patients undergoing balloon angioplasty of [[saphenous vein graft]] [[lesion]]s, particularly those with recent [[total occlusion]].


Distal embolization occurs in approximately 10% of patients with an acute myocardial infarction undergoing PCI. Embolic complications occur more often in patients with acute MI and in patients undergoing balloon angioplasty of SVG lesions, particularly those with recent occlusion.
===Diagnosis===
====Coronary Angiography: Distal Embolization====
[[File:Distal embolization.gif|left|250px]]
<br clear="left"/>
===Treatment===
*100% O2, [[Narcotic]]s, Suction vs hemopump, and [[Verapamil]]


==Air Embolus==
==Distal Embolization Examples==
*Often from manifold injections (contrast or flush); increase risk with pressurized flush
===[[Distal embolization case 1|Case 1]]===
*Small amount well tolerated; larger amount causes “air-lock”
 
*Treatment: 100% O2, Narcotics, Suction vs “hemopump”, and Verapamil
===[[Distal embolization case 2|Case 2]]===
 
===[[Distal embolization case 3|Case 3]]===
 
===[[Distal embolization case 4|Case 4]]===
 
===[[Distal embolization case 5|Case 5]]===
 
===[[Distal embolization case 6|Case 6]]===
 
===[[Distal embolization case 7|Case 7]]===
 
===[[Distal embolization case 8|Case 8]]===
 
===[[Distal embolization case 9|Case 9]]===
 
===[[Distal embolization case 10|Case 10]]===
 
===[[Distal embolization case 11|Case 11]]===
 
===[[Distal embolization case 12|Case 12]]===
 
===[[Distal embolization case 13|Case 13]]===
 
===[[Distal embolization case 14|Case 14]]===
 
===[[Distal embolization case 15|Case 15]]===
 
===[[Distal embolization case 16|Case 16]]===
 
===[[Distal embolization case 17|Case 17]]===
 
===[[Distal embolization case 18|Case 18]]===
 
===[[Distal embolization case 19|Case 19]]===
 
===[[Distal embolization case 20|Case 20]]===


==References==
==References==
#ref1 pmid=8187116 This is free space so that you can describe the reference if you want
{{Reflist|2}}
 
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Latest revision as of 16:43, 3 May 2014

Percutaneous coronary intervention Microchapters

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Distal Embolization
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hardik Patel, M.D., Sapan Patel M.B.B.S

Overview

Distal embolization during percutaneous coronary intervention is defined as either partial or complete occlusion of an instrumented major epicardial coronary artery or a branch due to downstream movement of either thrombus, atheroma, fracture of the distal tip of a coronary guidewire, an undeployed stent or air.[1] It is manifested clinically as either chest pain, ST segment elevation, no reflow during the procedure and / or a rise in biomarkers of myonecrosis (CK-MB or troponin) following the PCI.

Causes

Epidemiology and Demographics

Distal embolization occurs in approximately 10% of patients with an acute myocardial infarction undergoing PCI. Embolic complications occur more often in patients with acute MI and in patients undergoing balloon angioplasty of saphenous vein graft lesions, particularly those with recent total occlusion.

Diagnosis

Coronary Angiography: Distal Embolization


Treatment

Distal Embolization Examples

Case 1

Case 2

Case 3

Case 4

Case 5

Case 6

Case 7

Case 8

Case 9

Case 10

Case 11

Case 12

Case 13

Case 14

Case 15

Case 16

Case 17

Case 18

Case 19

Case 20

References

  1. Ishizaka N, Issiki T, Saeki F, Furuta Y, Ikari Y, Yamaguchi T (1994). "Predictors of myocardial infarction after distal embolization of coronary vessels with percutaneous transluminal coronary angioplasty. Experience of 21 consecutive patients with distal embolization". Cardiology. 84 (4–5): 298–304. PMID 8187116. |access-date= requires |url= (help)


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