Langerhans cell histiocytosis history and symptoms: Difference between revisions
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{{Langerhans cell histiocytosis}} | {{Langerhans cell histiocytosis}} | ||
{{CMG}} | {{CMG}} {{AE}} {{HL}} | ||
==History and Symptoms== | ==Overview== | ||
Common symptoms of Langerhans cell histiocytosis include [[bone]] pain, [[rash]], [[fever]], and [[failure to thrive]].<ref name="wiki">Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016</ref><ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref><ref name="PDQ">Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016</ref> | |||
==History== | |||
* When evaluating a patient for Langerhans cell histiocytosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough medication review. Other specific areas of focus when obtaining the history are outlined below:<ref name="PDQ">Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016</ref> | |||
** Review family history for members with positive history of the disease | |||
** Growth velocity chart | |||
** Any history of excessive thirst and urination | |||
==Symptoms== | |||
* '''Common symptoms of Langerhans cell histiocytosis among children include:'''<ref name="wiki">Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016</ref><ref name="radio"> Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016</ref><ref name="PDQ">Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016</ref> | |||
:*[[Abdominal pain]] | |||
:*[[Bone pain]] | |||
:*[[Delayed puberty]] | |||
:*[[Dizziness]] | |||
:*Irritability | |||
:*[[Failure to thrive]] | |||
:*[[Fever]] | |||
:*[[Polyurea]] | |||
:*[[Headache]] | |||
:*Limping | |||
:*Mental deterioration | |||
:*[[Rash]] | |||
:*[[Seizures]] | |||
:*[[Short stature]] | |||
:*Thirst | |||
:*[[Vomiting]] | |||
:*[[Weight loss]] | |||
* '''Common symptoms of Langerhans cell histiocytosis among adults include:''' <ref>{{Cite journal | |||
| author = [[Elena Gkrouzman]], [[Rene H. Cuadra]] & [[Jason Jacob]] | |||
| title = Langerhans Cell Histiocytosis of the Bone Presenting as Back Pain: An Unusual Diagnosis for a Common Complaint | |||
| journal = [[Connecticut medicine]] | |||
| volume = 79 | |||
| issue = 7 | |||
| pages = 409–414 | |||
| year = 2015 | |||
| month = August | |||
| pmid = 26411178 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[Hiroyuki Tsuchie]], [[Kyoji Okada]], [[Hiroyuki Nagasawa]], [[Michihiro Yano]], [[Hiroshi Nanjyo]] & [[Yoichi Shimada]] | |||
| title = Langerhans cell histiocytosis of the sternum | |||
| journal = [[Upsala journal of medical sciences]] | |||
| volume = 114 | |||
| issue = 2 | |||
| pages = 121–125 | |||
| year = 2009 | |||
| month = | |||
| doi = 10.1080/03009730802642360 | |||
| pmid = 19396700 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[Koray Aydogdu]], [[Ersin Gunay]], [[Gokturk Findik]], [[Sibel Gunay]], [[Yetkin Agackiran]], [[Sadi Kaya]], [[Nurettin Karaoglanoglu]] & [[Irfan Tastepe]] | |||
| title = Pulmonary Langerhans cell histiocytosis; characteristics of 11 cases | |||
| journal = [[Tuberkuloz ve toraks]] | |||
| volume = 61 | |||
| issue = 4 | |||
| pages = 333–341 | |||
| year = 2013 | |||
| month = | |||
| pmid = 24506750 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[A. Artigues Barcelo]], [[P. Guiscafre Fontirroig]], [[P. de Miguel Sebastian]], [[R. M. Salgado]] & [[M. T. Albiol Varella]] | |||
| title = [Fever and hyperprolactinaemia as the onset of Langerhans cell histiocytosis] | |||
| journal = [[Anales de medicina interna (Madrid, Spain : 1984)]] | |||
| volume = 22 | |||
| issue = 11 | |||
| pages = 535–537 | |||
| year = 2005 | |||
| month = November | |||
| pmid = 16454588 | |||
}}</ref> | |||
:*[[Bone pain]] | |||
:*[[Chest pain]] | |||
:*[[Cough]] | |||
:*[[Fever]] | |||
:*[[Malaise]] | |||
:*[[Polyurea]] | |||
:*[[Rash]] | |||
:*[[Shortness of breath]] | |||
:*[[Polydipsia]] | |||
:*[[Weight loss]] | |||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Hematology]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category: | [[Category:Medicine]] | ||
[[Category:Dermatology]] | |||
[[Category:Surgery]] |
Latest revision as of 00:01, 26 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Common symptoms of Langerhans cell histiocytosis include bone pain, rash, fever, and failure to thrive.[1][2][3]
History
- When evaluating a patient for Langerhans cell histiocytosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough medication review. Other specific areas of focus when obtaining the history are outlined below:[3]
- Review family history for members with positive history of the disease
- Growth velocity chart
- Any history of excessive thirst and urination
Symptoms
- Abdominal pain
- Bone pain
- Delayed puberty
- Dizziness
- Irritability
- Failure to thrive
- Fever
- Polyurea
- Headache
- Limping
- Mental deterioration
- Rash
- Seizures
- Short stature
- Thirst
- Vomiting
- Weight loss
References
- ↑ 1.0 1.1 Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016
- ↑ 2.0 2.1 Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016
- ↑ 3.0 3.1 3.2 Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016
- ↑ Elena Gkrouzman, Rene H. Cuadra & Jason Jacob (2015). "Langerhans Cell Histiocytosis of the Bone Presenting as Back Pain: An Unusual Diagnosis for a Common Complaint". Connecticut medicine. 79 (7): 409–414. PMID 26411178. Unknown parameter
|month=
ignored (help) - ↑ Hiroyuki Tsuchie, Kyoji Okada, Hiroyuki Nagasawa, Michihiro Yano, Hiroshi Nanjyo & Yoichi Shimada (2009). "Langerhans cell histiocytosis of the sternum". Upsala journal of medical sciences. 114 (2): 121–125. doi:10.1080/03009730802642360. PMID 19396700.
- ↑ Koray Aydogdu, Ersin Gunay, Gokturk Findik, Sibel Gunay, Yetkin Agackiran, Sadi Kaya, Nurettin Karaoglanoglu & Irfan Tastepe (2013). "Pulmonary Langerhans cell histiocytosis; characteristics of 11 cases". Tuberkuloz ve toraks. 61 (4): 333–341. PMID 24506750.
- ↑ A. Artigues Barcelo, P. Guiscafre Fontirroig, P. de Miguel Sebastian, R. M. Salgado & M. T. Albiol Varella (2005). "[Fever and hyperprolactinaemia as the onset of Langerhans cell histiocytosis]". Anales de medicina interna (Madrid, Spain : 1984). 22 (11): 535–537. PMID 16454588. Unknown parameter
|month=
ignored (help)