Vulvar cancer: Difference between revisions

	Vulvar cancer Microchapters
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Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Vulvar cancer from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
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Surgery
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Case #1
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Latest revision as of 16:45, 8 May 2019

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2] Syed Musadiq Ali M.B.B.S.[3]

Synonyms and keywords: Vulva cancer, cancer of vulva, vulvar carcinoma, vulvar neoplasm, neoplasm of vulva, malignant tumor of vulva, primary vulval cancer, primary vulvar cancer, primary vulva cancer, vulval carcinoma, vulva carcinoma, carcinoma of vulva, vulval cancer, vulval neoplasia.

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Vulvar cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

External links

Information from the National Cancer Institute

@@ Line 1: / Line 1: @@
 __NOTOC__
 '''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
+{{Vulvar cancer}}
+{{CMG}}{{AE}}{{MD}}{{sali}}
-{{Infobox_Disease
+{{SK}} Vulva cancer, cancer of vulva, vulvar carcinoma, vulvar neoplasm, neoplasm of vulva, malignant tumor of vulva, primary vulval cancer, primary vulvar cancer, primary vulva cancer, vulval carcinoma, vulva carcinoma, carcinoma of vulva, vulval cancer, vulval neoplasia.
- | Name           = {{PAGENAME}}
- | Image          =
- | Caption        =
- | DiseasesDB     = 14013
- | ICD10          = {{ICD10|C|51|.9|c|51}}
- | ICD9           = {{ICD9|184.4}}
- | ICDO           =
- | OMIM           =
- | MedlinePlus    = 000902
- | MeshID         =
-}}
-{{Vulvar cancer}}
-{{CMG}}
 ==[[Vulvar cancer overview|Overview]]==
-== Signs and Symptoms ==
+==[[Vulvar cancer historical perspective|Historical Perspective]]==
-Typically a lesion is present in form of a lump or [[ulceration]], often associated with itching, irritation, sometimes local bleeding and discharge. Also [[dysuria]], [[dyspareunia]] and pain may be noted.  Because of modesty or embarrassment, symptoms may not be heeded in a timely fashion.
-Melanomas tend to display the typical dark discoloration.
-Adenocarcinoma can arise from the [[Bartholin gland]] and results in a lump that may be quite painful.
-== Diagnosis ==
-Examination of the vulva is part of the gynecologic evaluation and may reveal ulceration, a lump, or a mass. A suspicious lesion needs to undergo a [[biopsy]] that generally can be performed in an office setting under [[local anesthesia]]. Small lesion can be excised under local anesthesia.
-Supplemental evaluation may include a [[chest X-ray]], an [[IVP]], [[cystoscopy]] and [[proctoscopy]], as well as blood counts and metabolic assessment.
-== Differential diagnosis ==
+==[[Vulvar cancer classification|Classification]]==
-Other neoplastic lesions that need to be considered in the differential diagnosis are Paget disease of the vulva  and VIN. Non-neoplastic vulvar disease includes [[lichen sclerosus]], squamous cell [[hyperplasia]], and [[vulvar vestibulitis]]. Infectious disease lesions can be caused by a  number of diseases including [[herpes genitalis]], [[human papillomavirus]],  [[syphilis]], [[chancroid]], [[granuloma inguinale]], and [[lymphogranuloma venereum]].
-== Etiology ==
+==[[Vulvar cancer pathophysiology|Pathophysiology]]==
-The etiology of the cancer is unclear; however, some condition such as [[condyloma]] or squamous [[dysplasia]]s may have preceded the cancer. [[Human papillomavirus]] (HPV) is suspected to be a possible risk factor in the etiology of vulvar cancer. Patients infected with [[HIV]] tend to be more susceptible to vulvar malignancy. Also, smokers tend to be at higher risk.
-== Staging ==
+==[[Vulvar cancer causes|Causes]]==
-Preclinical staging has been supplemented by surgical staging since 1988.  [[International Federation of Gynecology and Obstetrics|FIGO]]’s revised staging TNM classification system uses criteria of tumor size (T), involvement of lymph nodes (N), and metastasis (M). Stage I describes the early stage of the cancer that still appears to be confined to the site of origin, stage II and III define less or more extensive extensions to neighboring tissue and lymph nodes, while stage IV indicates metastatic disease.<ref name ="figo">{{cite web | url = http://www.igcs.org/guidelines/guideline_staging-booklet.pdf| author = International Federation of Gynecologists and Obstetricians (FIGO)| title = Staging classification and clinical practice guidelines of gynaecologic cancers | year = 2000 |accessdate = 2006-10-13}}</ref>
-== Treatment ==
+==[[Vulvar cancer differential diagnosis|Differentiating Vulvar cancer from other Diseases]]==
-Staging and treatment are generally handled by an [[oncologist]] familiar with gynecologic cancer. The extent of the surgery is dictated by the surgical staging.<ref name="figo"/>
+==[[Vulvar cancer epidemiology and demographics|Epidemiology and Demographics]]==
-[[Surgery]] is a mainstay of therapy and usually accomplished by use of a [[radical vulvectomy]], removal of vulvar tissue as well as the removal of lymph nodes from the inguinal and femoral areas. Complications of such surgery include wound infection, sexual dysfunction, edema and thrombosis.
+==[[Vulvar cancer risk factors|Risk Factors]]==
-Surgery is significantly more extensive when vulvar cancer has spread to adjacent organs such as urethra, vagina, and rectum.
+==[[Vulvar cancer screening|Screening]]==
-In cases of early vulvar carcinoma the surgery may be less radical and disfiguring and consist of wide excision or a simple vulvectomy.
-[[Radiation therapy]] and [[chemotherapy]] are usually not a primary choice of therapy but may be used in selected cases of advanced vulvar cancer.
+==[[Vulvar cancer natural history|Natural History, Complications and Prognosis]]==
-== Prognosis ==
+==Diagnosis==
-The prognosis of vulvar cancer shows overall about a 75% [[five year survival rate]], but, of course, individually affected by many factors, notably stage and type of the lesion and age and general medical health. Five-year survival is down to about 20% when pelvic lymph nodes are involved but better than 90% for patients with stage I lesions. Thus early diagnosis is imperative.
+[[Vulvar cancer staging|Staging]] | [[Vulvar cancer history and symptoms|History and Symptoms]] | [[Vulvar cancer physical examination|Physical Examination]] | [[Vulvar cancer laboratory findings|Laboratory Findings]] | [[Vulvar cancer x ray|X Rays]] | [[Vulvar cancer CT|CT]] | [[Vulvar cancer MRI|MRI]] | [[Vulvar cancer ultrasound|Ultrasound]] | [[Vulvar cancer other imaging findings|Other Imaging Findings]] | [[Vulvar cancer other diagnostic studies|Other Diagnostic Studies]]
-== Help and Support ==
+==Treatment==
+[[Vulvar cancer medical therapy|Medical therapy]] | [[Vulvar cancer surgery|Surgery]] | [[Vulvar cancer primary prevention|Primary Prevention]]  | [[Vulvar cancer secondary prevention|Secondary Prevention]] | [[Vulvar cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Vulvar cancer future or investigational therapies|Future or Investigational Therapies]]
-There is a support group for women who have/had vulva cancer/other vulva problems called VACO (Vulva Awareness Campaign Organisation). The website address for this is vaco.co.uk. It's just as easy as checking breasts. Women must check their vulva and to report any problems to their doctor as soon as possible.
+==Case Studies==
+[[Vulvar cancer case study one|Case #1]]
-==References==
-{{reflist|2}}
 ==External links==
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-[[Category:Overview complete]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
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+[[Category:Medicine]]
-{{WikiDoc Sources}}
+[[Category:Gynecology]]