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{{Infobox_Disease |
__NOTOC__
  Name          = Seminoma |
{{Seminoma}}
  Image          = |
'''For patient information click [[Testicular cancer (patient information)|here]]'''.
  Caption        = |
  DiseasesDB    = 12966 |
  ICD10          = {{ICD10|C|62||c|60}} |
  ICD9          = {{ICD9|186}} |
  ICDO          = 9061 |
  OMIM          = 273300 |
  MedlinePlus    = |
  eMedicineSubj  = |
  eMedicineTopic = |
  MeshID        = D018239 |
}}
{{SI}}
{{CMG}}
==Overview==
'''Seminoma''' is one type of [[testicular cancer]]<ref>{{Dorlands|s_07|12728548}}</ref> that is believed to originate from the [[germinal epithelium]] of the [[seminiferous tubule]]s.  


==Presentation==
{{CMG}}{{AE}}{{SR}}
They produce bulky masses that can be up to ten times the size of a normal testis.


{{SK}} Pure seminoma; Classical seminoma; Testicular seminoma; Anterior mediastinal germ cell tumors; Anterior mediastinal germ cell tumours; Seminomatous germ cell tumor; Seminomatous germ cell tumors; Seminomatous germ cell tumour; Seminomatous germ cell tumours; Seminomatous GCT; Testicular cancer; Testicular malignant germ cell tumor
==[[Seminoma overview|Overview]]==
==[[Seminoma historical perspective|Historical Perspective]]==
==[[Seminoma classification|Classification]]==
==[[Seminoma pathophysiology|Pathophysiology]]==
==[[Seminoma causes|Causes]]==
==[[Seminoma differential diagnosis|Differentiating Seminoma from other Diseases]]==
==[[Seminoma epidemiology and demographics|Epidemiology and Demographics]]==
==[[Seminoma risk factors|Risk Factors]]==
==[[Seminoma screening|Screening]]==
==[[Seminoma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==Diagnosis==
==Diagnosis==
{{Gene|POU2AF1}} and {{Gene|PROM1}} have been proposed as possible markers.<ref name="pmid17785371">{{cite journal |author=Gashaw I, Dushaj O, Behr R, ''et al'' |title=Novel germ cell markers characterize testicular seminoma and fetal testis |journal=Mol. Hum. Reprod. |volume=13 |issue=10 |pages=721–7 |year=2007 |pmid=17785371 |doi=10.1093/molehr/gam059}}</ref>


Peak incidence occurs in the 4th decade of life.  Histology shows large cells, clear sytoplasm, distinct cell membranes, and septated arcitecture.
[[Seminoma staging|Staging]] | [[Seminoma history and symptoms|History and Symptoms]] | [[Seminoma physical examination|Physical Examination]] | [[Seminoma laboratory findings|Laboratory Findings]] | [[Seminoma chest x ray|Chest X Ray]] | [[Seminoma CT|CT]] | [[Seminoma MRI|MRI]] | [[Seminoma ultrasound|Ultrasound]] | [[Seminoma other imaging findings|Other Imaging Findings]] | [[Seminoma other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
In recent years, these tumors have been shown to have dramatic sensitivity to both [[radiotherapy]] and [[cytotoxic]] [[chemotherapy]]. The management of childhood seminoma is similar to that of adult seminoma. [[Orchiectomy]] is required in almost all cases.


==References==
[[Seminoma medical therapy|Medical Therapy]] | [[Seminoma surgery|Surgery]] | [[Seminoma primary prevention|Primary Prevention]] | [[Seminoma secondary prevention|Secondary Prevention]] | [[Seminoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Seminoma future or investigational therapies|Future or Investigational Therapies]]
{{reflist}}
 
==Case Studies==
 
[[Seminoma case study one|Case #1]]
 


{{Soft tissue tumors and sarcomas }}
{{Soft tissue tumors and sarcomas }}
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Oncology stub]]
[[Category:Oncology stub]]
[[de:Seminom]]
[[Category:Disease]]
[[ja:精上皮腫]]
 


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Latest revision as of 16:35, 27 November 2017

Seminoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Seminoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

TNM
Stage Grouping

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Treatment - Stage I
Treatment - Stage II
Treatment - Stage III
Treatment - Recurrent

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Seminoma On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Seminoma

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Seminoma

CDC on Seminoma

Seminoma in the news

Blogs on Seminoma

Directions to Hospitals Treating Seminoma

Risk calculators and risk factors for Seminoma

For patient information click here.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Synonyms and keywords: Pure seminoma; Classical seminoma; Testicular seminoma; Anterior mediastinal germ cell tumors; Anterior mediastinal germ cell tumours; Seminomatous germ cell tumor; Seminomatous germ cell tumors; Seminomatous germ cell tumour; Seminomatous germ cell tumours; Seminomatous GCT; Testicular cancer; Testicular malignant germ cell tumor

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Seminoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging | History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1



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