Coccidioidomycosis: Difference between revisions

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VisualWikitext

Latest revision as of 21:00, 29 July 2020

Template:DiseaseDisorder infobox

This page is about clinical aspects of the disease. For microbiologic aspects of the causative organism(s), see Coccidioides immitis.

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Vidit Bhargava, M.B.B.S [3]; Aditya Ganti M.B.B.S. [4]

Synonyms and keywords: Coccidioides infection; Posadas-Wernicke disease; Valley fever; San Joaquin fever, Desert fever

Overview

Historical Perspective

Pathophysiology

Causes

Coccidioides Immitis | Coccidioides Posadasii

Differentiating Coccidioidomycosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Study

Case #1

External Links

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+__NOTOC__
 {{DiseaseDisorder infobox |
    Image       = Coccidioidomycosis_01.jpg |
-   Caption     = [[Histopathology|Histopathological]] changes in a case of coccidioidomycosis of the lung showing a large fibrocaseous nodule. |
+   Caption     = [[Histopathology|Histopathological]] changes in a case of coccidioidomycosis of the lung showing a large fibrocaseous nodule|
    Name        = Coccidioidomycosis |
-  ICD10       = {{ICD10|B|38||b|35}} |
-  ICD9        = {{ICD9|114}} |
-  MedlinePlus    = 001322 |
-  eMedicineSubj  = |
-  eMedicineTopic = |
-  eMedicine_mult = |
-  MeshID         = D003047 |
 }}
+{{About1|Coccidioides immitis}}
 {{Coccidioidomycosis}}
 '''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
-{{CMG}}
+{{CMG}}; {{AE}} {{RT}}; {{VB}}; {{ADG}}
+{{SK}} ''Coccidioides'' infection; Posadas-Wernicke disease; Valley fever; San Joaquin fever, Desert fever
 ==[[Coccidioidomycosis overview|Overview]]==
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 ==[[Coccidioidomycosis pathophysiology|Pathophysiology]]==
-==[[Coccidioidomycosis epidemiology and demographics|Epidemiology & Demographics]]==
+==Causes==
+[[Coccidioides immitis|Coccidioides Immitis]] | [[Coccidioides posadasii|Coccidioides Posadasii]]
+==[[Coccidioidomycosis differential diagnosis|Differentiating Coccidioidomycosis from other Diseases]]==
+==[[Coccidioidomycosis epidemiology and demographics|Epidemiology and Demographics]]==
 ==[[Coccidioidomycosis risk factors|Risk Factors]]==
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 ==[[Coccidioidomycosis screening|Screening]]==
-==[[Coccidioidomycosis causes|Causes]]==
+==[[Coccidioidomycosis natural history|Natural History, Complications and Prognosis]]==
-==[[Coccidioidomycosis differential diagnosis|Differentiating Coccidioidomycosis]]==
-==[[Coccidioidomycosis natural history|Complications & Prognosis]]==
 ==Diagnosis==
-[[Coccidioidomycosis history and symptoms|History and Symptoms]] | [[Coccidioidomycosis physical examination|Physical Examination]] | [[Coccidioidomycosis staging|Staging]] | [[Coccidioidomycosis laboratory tests|Laboratory tests]] | [[Coccidioidomycosis electrocardiogram|Electrocardiogram]]  | [[Coccidioidomycosis x ray|X Rays]] | [[Coccidioidomycosis CT|CT]] | [[Coccidioidomycosis MRI|MRI]] [[Coccidioidomycosis echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Coccidioidomycosis other imaging findings|Other images]] | [[Coccidioidomycosis other diagnostic studies|Alternative diagnostics]]
+[[Coccidioidomycosis history and symptoms|History and Symptoms]] | [[Coccidioidomycosis physical examination|Physical Examination]] |  [[Coccidioidomycosis laboratory tests|Laboratory Findings]] | [[Coccidioidomycosis chest x ray|Chest X Ray]] | [[Coccidioidomycosis CT|CT]] | [[Coccidioidomycosis MRI|MRI]]
 ==Treatment==
-[[Coccidioidomycosis medical therapy|Medical therapy]] | [[Coccidioidomycosis surgery|Surgical options]] | [[Coccidioidomycosis primary prevention|Primary prevention]]  | [[Coccidioidomycosis secondary prevention|Secondary prevention]] | [[Coccidioidomycosis cost-effectiveness of therapy|Financial costs]] | [[Coccidioidomycosis future or investigational therapies|Future therapies]]
+[[Coccidioidomycosis medical therapy|Medical Therapy]] | [[Coccidioidomycosis primary prevention|Primary Prevention]]  | [[Coccidioidomycosis secondary prevention|Secondary Prevention]] | [[Coccidioidomycosis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Coccidioidomycosis future or investigational therapies|Future or Investigational Therapies]]
-[[Image:Geographic_Distribution_of_Coccidioidomycosis_02.png|left|thumb|300px|Geographic distribution of coccidioidomycosis.]]
-==Occurrence==
-California state prisons have been particularly affected by Coccidioidomycosis, as far back as 1919. In 2005 and 2006, the Pleasant Valley State Prison near Coalinga and Avenal State Prison near Avenal on the western side of the San Joaquin Valley had the highest incidence rate in 2005, of at least 3,000 per 100,000 [http://www.blackwell-synergy.com/doi/abs/10.1196/annals.1406.011].
-==Biological Warfare==
-''C. immitis'' was investigated by the United States during the 1950s and 1960s as a potential biological weapon. The Cash strain received the military symbol OC, and original hopes were for its use as an incapacitant. As medical epidemiology later made clear, OC would have lethal effects on several segments of the population, so it was later considered a lethal agent. It was never standardized, and beyond a few field trials, it was never weaponized. Most military work on OC was on vaccines by the mid-1960s.
-==Diagnostic test==
+==Case Study==
-The fungal infection can be demonstrated by microscopic detection of diagnostic cells in body fluids, exudates, [[sputum]] and [[biopsy]]-tissue. With specific [[nucleotide]] primers ''C.immitis'' [[DNA]] can be amplified by [[PCR]]. It can also be detected in culture by morphological identification or by using molecular probes that hybridize with ''C.immitis'' [[RNA]]. An indirect demonstration of fungal infection can be achieved also by serologic analysis detecting fungal [[antigen]] or host [[antibody]] produced against the fungus.
+[[Coccidioidomycosis case study one|Case #1]]
-==Pathology==
+==External Links==
-<youtube v=RtpvzCfFwfg/>
+* [http://www.cdc.gov/fungal/coccidioidomycosis/ U.S. Centers for Disease Control and Prevention page on Coccidioidomycosis]
-==Popular culture==
-The illness is mentioned in episode Lines in the Sand of the TV Show ''House'', as the cause of a young girl's loss of inhibition. The illness does not actually cause loss of inhibition, nor does it cause milky tears. This was not a factual error in the episode: House was tricking the girl, however this was not obvious to many viewers.
-It is also the center of an episode of the TV series Bones, ''The Man In the Fallout Shelter''. After being exposed to the fungus, the team was quarantined over Christmas to determine whether or not they had become infected. It was erroneously claimed to be contagious from person to person.
-==References==
-{{Reflist|2}}
-==External links==
-* [http://www.cdc.gov/ncidod/dbmd/diseaseinfo/coccidioidomycosis_t.htm U.S. Centers for Disease Control and Prevention page on Coccidioidomycosis]
 * [http://www.nlm.nih.gov/medlineplus/ency/article/001322.htm Medline Plus Entry for Coccidioidomycosis]
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+[[Category:Pulmonology]]
+[[Category:Fungal diseases]]
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