Leishmaniasis case study one: Difference between revisions
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== | ==Case #1== | ||
====Clinical Summary==== | |||
This 28-year-old white male presented to the dermatology clinic complaining of sores on his arms. On examination, two lesions measuring 0.7 to 1.5 cm in diameter were present on his right arm. These lesions showed central ulceration and a raised, indurated margin surrounding the ulcer. The lesions had developed over approximately one month. The patient had applied topical antibiotics, which had no effect. The patient had recently returned from a World Wildlife Fund study site in the Amazon region of Brazil, where he had been conducting field research in the rain forest. A biopsy was taken from the raised edge of one of the ulcers. | |||
====Histopathological Findings==== | |||
[http://www.peir.net Images courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] | |||
[[Image:Leishmaniasis 001.jpg|left|thumb|400px|In this photograph of the skin lesion seen in this patient, note the raised edges (arrows) and the ulcerated center. ]] | |||
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[[Image:Leishmaniasis 002.jpg|left|thumb|400px|This is a low-power photomicrograph of the biopsy taken from this skin lesion. The ulcerated surface is at the top. Note that the specimen is heavily infiltrated with inflammatory cells. ]] | |||
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[[Image:Leishmaniasis 003.jpg|left|thumb|400px|This is a higher-power photomicrograph of this biopsy. The ulcerated surface is seen on the top of the section. Again, note that the specimen is heavily infiltrated with inflammatory cells.]] | |||
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[[Image:Leishmaniasis 004.jpg|left|thumb|400px|This high-power photomicrograph of the biopsy specimen shows more clearly the heavily infiltrate of inflammatory cells. Note the small blue structures inside the inflammatory cells (arrows).]] | |||
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[[Image:Leishmaniasis 005.jpg|left|thumb|400px|This is a high-power photomicrograph of an inflammatory cell containing cytoplasmic organisms (arrows). ]] | |||
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[[Image:Leishmaniasis 006.jpg|left|thumb|400px|This is a high-power photomicrograph of a touch prep made from the skin lesion at the time of biopsy. A single macrophage can be seen with intracytoplasmic leishmania organisms (arrows). ]] | |||
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==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Zoonoses]] | |||
[[Category:Parasitic diseases]] | [[Category:Parasitic diseases]] | ||
[[Category:Tropical disease]] | [[Category:Tropical disease]] |
Latest revision as of 18:09, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Case #1
Clinical Summary
This 28-year-old white male presented to the dermatology clinic complaining of sores on his arms. On examination, two lesions measuring 0.7 to 1.5 cm in diameter were present on his right arm. These lesions showed central ulceration and a raised, indurated margin surrounding the ulcer. The lesions had developed over approximately one month. The patient had applied topical antibiotics, which had no effect. The patient had recently returned from a World Wildlife Fund study site in the Amazon region of Brazil, where he had been conducting field research in the rain forest. A biopsy was taken from the raised edge of one of the ulcers.
Histopathological Findings