Kikuchi disease: Difference between revisions

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	Kikuchi disease;
	Micrograph of a lymph node with Kikuchi disease showing the characteristic features (abundant histiocytes, necrosis without neutrophils) on H&E stain.

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VisualWikitext

Latest revision as of 18:07, 18 September 2017

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Histiocytic necrotizing lymphadenitis; Kikuchi-Fujimoto disease; Kikuchi necrotizing lymphadenitis; phagocytic necrotizing lymphadenitis; subacute necrotizing lymphadenitis; necrotizing lymphadenitis

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Kikuchi disease from other Diseases

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

Treatment

Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters

For other causes of lymph node enlargement, see lymphadenopathy.

Template:WikiDoc Sources

@@ Line 1: / Line 1: @@
+__NOTOC__
+'''For patient information, click [[{{PAGENAME}} (patient information)|here]]'''
 {{Infobox_Disease |
-   Name           = {{PAGENAME}} |
+   Name           = Kikuchi disease|
-   Image          = |
+   Image          = Kikuchi disease.jpg|
-   Caption        = |
+   Caption        = [[Micrograph]] of a [[lymph node]] with Kikuchi disease showing the characteristic features (abundant [[histiocytes]], [[necrosis]] without [[neutrophil]]s) on [[H&E stain]].|
-  DiseasesDB     = |
-  ICD10          = |
-  ICD9           = |
-  ICDO           = |
-  OMIM           = |
-  MedlinePlus    = |
-  eMedicineSubj  = |
-  eMedicineTopic = |
-  MeshID         = |
 }}
-{{SI}}
+{{Kikuchi disease}}
 {{CMG}}
-'''''Synonyms and keywords:''''' Histiocytic necrotizing lymphadenitis
+{{SK}} Histiocytic necrotizing lymphadenitis; Kikuchi-Fujimoto disease; Kikuchi necrotizing lymphadenitis; phagocytic necrotizing lymphadenitis; subacute necrotizing lymphadenitis; necrotizing lymphadenitis
-==Overview==
+==[[Kikuchi disease overview|Overview]]==
-'''Kikuchi's disease''' (histiocytic necrotizing lymphadenitis) is a rare, non-cancerous enlargement of the [[lymph node]]s: the diagnosis can be confirmed by lymph node biopsy. It was originally described in Japan by Dr M. Kikuchi in 1972.<ref>Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes. ''Acta Hematol Jpn'' 1972;35:379–80.<!--No PMID--></ref>
+==[[Kikuchi disease historical perspective|Historical Perspective]]==
+==[[Kikuchi disease pathophysiology|Pathophysiology]]==
-==Cause==
+==[[Kikuchi disease causes|Causes]]==
-*The cause for this disease has not been established.
-*Kikuchi's disease has been reported to be associated with infections such as:
+==[[Kikuchi disease differential diagnosis|Differentiating Kikuchi disease from other Diseases]]==
-:*[[epstein-Barr virus]],
-:*[[human herpesvirus 6]],
-:*[[toxoplasmosis]], and
-:*[[Human T-lymphotropic virus]]
-==Prognsis==
+==[[Kikuchi disease epidemiology and demographics|Epidemiology and Demographics]]==
-*Kikuchi's disease is a self limiting illness.
-*In most reported cases, it is common for the debilitating symptoms to last for half a year; however, the disease does return to some patients after time.
+==[[Kikuchi disease natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
-==Clinical presentation==
+==Diagnosis==
-The clinical presentation is very similar symptoms to [[Hodgkin's lymphoma]] which has led to the misdiagnosis of some patients and resulting in dangerous cancer treatment to those suffering from Kikuchi's disease.
+[[Kikuchi disease history and symptoms|History and Symptoms]] | [[Kikuchi disease physical examination|Physical Examination]] | [[Kikuchi disease laboratory findings|Laboratory Findings]] | [[Kikuchi disease chest x ray|Chest X Ray]] | [[Kikuchi disease CT|CT]] | [[Kikuchi disease MRI|MRI]] | [[Kikuchi disease ultrasound|Ultrasound]] | [[Kikuchi disease other diagnostic studies|Other Diagnostic Studies]]
-====Symptoms:====
+==Treatment==
-The symptoms of Kikuchi's are the following:
+[[Kikuchi disease medical therapy|Medical Therapy]] | [[Kikuchi disease surgery|Surgery]] | [[Kikuchi disease cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Kikuchi disease future or investigational therapies|Future or Investigational Therapies]]
-* [[Lymphadenopathy]]
+==Case Studies==
-* Drenching night sweats
+[[Kikuchi disease case study one|Case #1]]
-* Fever
-* Bone-joint pain
-* Loss of appetite
-* Unexplained weight loss
-* General weakness
-* Fatigue
-* Mental unfocus
-==Treatment==
+==Related Chapters==
-*The cause for this disease has not been established, and there is also no cure.
-*Kikuchi's patients are able to treat some symptoms and wait weeks to months before the symptoms of Kikuchi's has been suppressed.
-==Related chapters==
 *For other causes of lymph node enlargement, see [[lymphadenopathy]].
-==References==
-{{reflist|2}}
-{{Symptoms and signs}}
-{{SIB}}
-[[Category:Disease]]
-[[Category:Infectious disease]]
 [[Category:Rare diseases]]


Kikuchi disease
Micrograph of a lymph node with Kikuchi disease showing the characteristic features (abundant histiocytes, necrosis without neutrophils) on H&E stain.