Brain tumor epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
Epidemiological record suggests a growing share each year of infants and children in the United States affected by brain tumors.
In 2012, the prevalence and incidence of brain tumors were 148,818 and 6.4 per 100,000 persons per year respectively. The case-mortality rate of brain tumors is 4.4 per 100,000 persons per year. Patients of all age-group develop this cancer. Males are more affected with gliomas than females. Females are more affected with meningiomas. It usually affects individuals of the caucasian race. African Americans are less likely to develop this cancer.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
Brain tumors account for 85% to 90% of all primary central nervous system (CNS) tumors.
===Prevalence===
*In 2012, there were an estimated 148,818 people living with brain and other nervous system cancer in the United States.<ref name="seer">National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015.http://seer.cancer.gov</ref>


It is estimated that 22,340 new cases of primary  
===Incidence===
malignant brain and central nervous system (CNS)
*Available registry data from the Surveillance, Epidemiology, and End Results (SEER) database for 2012 indicate that the combined incidence of primary CNS tumors in the United States is 6.4 per 100,000 persons per year, with an estimated mortality of 4.4 per 100,000 persons per year.  These rates are age-adjusted and based on 2008-2012 cases and deaths.
tumors will be diagnosed in the United States in
*Estimated new cases and deaths from brain tumors and other nervous system tumors in the United States in 2015
2011; of those, approximately 3,000 will be new cases  
**''New cases'': 22,850
of childhood primary brain and CNS tumors.The
**''Percentage'' of all new cancer cases: 1.4%
incidence and mortality rates for cancers that originate
**''Deaths'': 15,320<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq</ref>
in the brain and CNS have decreased slightly in the  
**''Percentage'' of all cancer deaths: 2.6%
past decade. Both incidence and mortality rates are
*In ''2015'', it is estimated that there will be 22,850 new cases of brain and other nervous system cancer and an estimated 15,320 people will die of this disease.
substantially higher for whites than for people of  
other racial/ethnic groups. In all racial/ethnic groups,
men have higher incidence and mortality rates than
women.
Brain tumors are the leading cause of death from solid
tumor cancers in children; brain and CNS cancers
make up approximately 27 percent of all childhood
cancers. The incidence rate of brain and CNS cancers
in children has risen slightly over the past three
decades, but the death rate has dropped slightly over
this period.
It is estimated that approximately $3.7 billion is
spent in the United States each year on brain cancer  
treatment.


'''Survival'''
===Age===
*Brain tumors are seen in all age-groups.


* SEER(Surveillance, Epidemiology and End Results): The five–year relative survival rate following diagnosis of a primary malignant brain and central nervous system tumor (including lymphomas and leukemias, tumors of the pituitary and pineal glands, and olfactory tumors of the nasal cavity) is 32.3% for males and 35.5% for females (1995–2008 data). <ref> Estimated by CBTRUS using Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence - SEER 17 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2010 Sub (1973-2008 varying) - Linked To County Attributes - Total U.S., 1969-2009 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2011 (updated 10/28/2011), based on the November 2010 submission.</ref>
===Gender===
* Gliomas are more frequent in '''men''' and [[meningiomas]] are more frequent in '''women'''.


* SEER: Five–year relative survival rates following diagnosis of a primary malignant brain and central nervous system tumor (including lymphomas and leukemias, tumors of the pituitary and pineal glands, and olfactory tumors of the nasal cavity) by age of diagnosis (1995–2008 data):
===Race===
*Caucasians > African Americans


<blockquote>
===Others===
{| border="0" cellspacing="0" cellpadding="5"<br>
*'''Lifetime Risk of Developing Cancer''' : Approximately 0.6 percent of men and women will be diagnosed with brain and other nervous system cancer at some point during their lifetime, based on 2010-2012 data.
|-<br>
| Age 0-19 years: 72.6%<br>
| Age 55-64 years: 17.7%<br>
|-<br>
| Age 20-44 years: 57.1%<br>
| Age 65-74 years: 10.0%<br>
|-<br>
| Age 45-54 years: 31.6%<br>
| Age 75 or older: 5.6%<br>
|}
</blockquote>
 
===Brain tumors in infants and children===
In 2000 approximately 2.76 children per 100,000 will be affected by a [[brain tumor|CNS tumor]] in the United States each year.  This rate has been increasing and by 2005 was 3.0 children per 100,000.  This is approximately 2,500-3,000 pediatric brain tumors occurring each year in the US.  The tumor incidence is increasing by about 2.7% per year.
The [[Central Nervous System|CNS]] Cancer survival rate in children is approximately 60%.<ref>[http://seer.cancer.gov/publications/childhood/cns.pdf  See Table 11.2 Survival Rate]</ref>  However, this rate varies with the age of onset (younger has higher mortality) and cancer type.
 
In children under 2, about 70% of brain tumors are [[medulloblastoma]], [[ependymoma]], and low-grade [[glioma]]. Less commonly, and seen usually in infants, are [[teratoma]] and [[ATRT|atypical teratoid rhabdoid tumor]].<ref>[http://www.childhoodbraintumor.org/InfantileBrainTumors.html ''Infantile Brain Tumors'' by Brian Rood for The Childhood Brain Tumor Foundation] (accessed July 2007)</ref>


==References==
==References==
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Brain]]
[[Category:Brain]]
[[Category:Neurology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Neurology]]
[[Category:Medicine]]
[[Category:Mature chapter]]
[[Category:Neurosurgery]]

Latest revision as of 20:41, 29 July 2020

Brain tumor Microchapters

Patient Information

Overview

Classification

Adult brain tumors
Glioblastoma multiforme
Oligodendroglioma
Meningioma
Hemangioblastoma
Pituitary adenoma
Schwannoma
Primary CNS lymphoma
Childhood brain tumors
Pilocytic astrocytoma
Medulloblastoma
Ependymoma
Craniopharyngioma
Pinealoma
Metastasis
Lung cancer
Breast cancer
Melanoma
Gastrointestinal tract cancer
Renal cell carcinoma
Osteoblastoma
Head and neck cancer
Neuroblastoma
Lymphoma
Prostate cancer

Causes

Differentiating Brain Tumor from other Diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

In 2012, the prevalence and incidence of brain tumors were 148,818 and 6.4 per 100,000 persons per year respectively. The case-mortality rate of brain tumors is 4.4 per 100,000 persons per year. Patients of all age-group develop this cancer. Males are more affected with gliomas than females. Females are more affected with meningiomas. It usually affects individuals of the caucasian race. African Americans are less likely to develop this cancer.

Epidemiology and Demographics

Brain tumors account for 85% to 90% of all primary central nervous system (CNS) tumors.

Prevalence

  • In 2012, there were an estimated 148,818 people living with brain and other nervous system cancer in the United States.[1]

Incidence

  • Available registry data from the Surveillance, Epidemiology, and End Results (SEER) database for 2012 indicate that the combined incidence of primary CNS tumors in the United States is 6.4 per 100,000 persons per year, with an estimated mortality of 4.4 per 100,000 persons per year. These rates are age-adjusted and based on 2008-2012 cases and deaths.
  • Estimated new cases and deaths from brain tumors and other nervous system tumors in the United States in 2015
    • New cases: 22,850
    • Percentage of all new cancer cases: 1.4%
    • Deaths: 15,320[2]
    • Percentage of all cancer deaths: 2.6%
  • In 2015, it is estimated that there will be 22,850 new cases of brain and other nervous system cancer and an estimated 15,320 people will die of this disease.

Age

  • Brain tumors are seen in all age-groups.

Gender

  • Gliomas are more frequent in men and meningiomas are more frequent in women.

Race

  • Caucasians > African Americans

Others

  • Lifetime Risk of Developing Cancer : Approximately 0.6 percent of men and women will be diagnosed with brain and other nervous system cancer at some point during their lifetime, based on 2010-2012 data.

References

  1. National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015.http://seer.cancer.gov
  2. National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq


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