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{{SI}}
{{Leg pain}}
{{CMG}}
'''For patient information click [[Leg pain (patient information)|here]]'''


{{CMG}}; '''Associate Editor(s)-in-Chief:''' [[User:Aditya Govindavarjhulla|Aditya Govindavarjhulla, M.B.B.S.]] [mailto:agovi@wikidoc.org], [[User:Raviteja Reddy Guddeti|Raviteja Guddeti, M.B.B.S.]] [mailto:ravitheja.g@gmail.com]


==Overview==
Leg pain is a common non-specific symptom that often has a musculoskeletal, metabolic or drug side effect basis.


===Complete Differential Diagnosis of the causes of Leg pain===
==Causes==
(By organ system)
 
{|style="width:80%; height:100px" border="1"
===Common Causes===
* Arterial [[thromboembolism]]
* [[Arthritis]]
* Autoimmune vascular disorders such as [[vasculitis]]
* [[Baker's cyst]]
* [[Cholesterol embolism]]
* Chronic [[venous insufficiency]]
* [[Connective tissue disease]]
* [[Coxsackie B]]
* [[Deep Vein Thrombosis]] ([[DVT]])
* [[Drug]]s, [[toxin]]s
* [[Hypocalcemia]]
* [[Hypokalemia]]
* [[Hyponatremia]]
* [[Leptospirosis]]
* Ligament damage
* Lumbar canal stenosis or [[spinal stenosis]]
* Muscle or tendon strain
* [[Night cramps]]
* [[Obliterating endarteritis]]
* [[Peripheral neuropathy]]
* [[Peripheral vascular disease]]
* Plexopathy
* Primary varicosis
* [[Radiculopathy]]
* [[Restless Leg Syndrome]]
* [[Venous thromboembolism]] ([[VTE]])
 
 
 
===Causes by Organ System===
{|style="width:50%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Aortoiliac occlusive disease]],[[Cholesterol Emboli Syndrome]],[[Deep Vein Thrombosis]],[[Peripheral Arterial Disease]],[[Thrombophlebitis]],[[Varicose veins]]
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Aortoiliac occlusive disease]], [[Cholesterol Emboli Syndrome]], [[Deep Vein Thrombosis]], [[Peripheral Arterial Disease]], [[Thrombophlebitis]], [[Varicose veins]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
Line 16: Line 50:
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Behcet's disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Abatacept Injection]],[[Acebutolol]],[[Acitretin]],[[Aldesleukin]],[[Alendronate]],[[Allopurinol]],[[Amikacin Sulfate Injection]],[[Anagrelide]],[[Anastrozole]],[[Aripiprazole]],[[Atazanavir]],[[Atenolol]],[[Atorvastatin]],[[Bevacizumab Injection]],[[Bortezomib]],[[Buspirone]],[[Capecitabine]],[[Celecoxib]],[[Celiac disease]],[[Clofarabine Injection]],[[Clonazepam]],[[Clopidogrel]],[[Cortisol]],[[Darbepoetin Alfa]],[[Docetaxel]],[[Epoetin Alfa Injection]],[[Ethacrynic Acid]],[[Etidronate]],[[Ezetimibe]],[[Fenofibrate]],[[Filgrastim]],[[Fluvastatin]],[[Gabapentin]],[[Galantamine]],[[Glatiramer Injection]],[[Ibandronate]],[[Iloprost]],[[Imatinib]],[[Infliximab Injection]],[[Interferon Alfa-2a and Alfa-2b Injection]],[[Interferon Alfacon-1 Injection]],[[Interferon beta-1a Intramuscular Injection]],[[Interferon Beta-1b Injection]],[[Interferon Gamma-1b Injection]],[[Lamivudine]],[[Latanoprost]],[[Leflunomide]],[[Letrozole]],[[Leuprolide]],[[Lovastatin]],[[Methimazole]],[[Methylergonovine]],[[Methylprednisolone]],[[Mifepristone]],[[Natalizumab injection ]],[[Ofloxacin ]],[[Paclitaxel]],[[Peginterferon alfa-2a]],[[Prednisone]],[[Pyrazinamide]],[[Quinupristin]] [[dalfopristin]],[[Ribavirin]],[[Rofecoxib]],[[Rosiglitazone]],[[Rosuvastatin]],[[Sunitinib ]],[[Tadalafil ]],[[Tamsulosin ]],[[Telbivudine ]],[[Temozolomide ]],[[Terbutaline]],[[Teriparatide]],[[Tiotropium]],[[Torsemide]],[[Valganciclovir]],[[Valsartan]],[[Vancomycin]],[[Vinblastine]],[[Vincristine]],[[Zalcitabine]],[[Ziprasidone]],[[Zolmitriptan]],[[Zolpidem]],
|bgcolor="Beige"| [[Abatacept Injection]], [[Acebutolol]], [[Acitretin]], [[Aldesleukin]], [[Alendronate]], [[Allopurinol]], [[Amikacin Sulfate Injection]], [[Anagrelide]], [[Anastrozole]], [[Aripiprazole]], [[Atazanavir]], [[Atenolol]], [[Atorvastatin]], [[Bevacizumab Injection]], [[Bortezomib]], [[Buspirone]], [[Capecitabine]], [[Celecoxib]], [[Celiac disease]], [[Clofarabine Injection]], [[Clonazepam]], [[Clopidogrel]], [[Cortisol]], [[Darbepoetin Alfa]], [[Docetaxel]], [[Epoetin Alfa Injection]], [[Ethacrynic Acid]], [[Etidronate]], [[Ezetimibe]], [[Fenofibrate]], [[Filgrastim]], [[Fluvastatin]], [[Gabapentin]], [[Galantamine]], [[Glatiramer Injection]], [[Ibandronate]], [[Iloprost]], [[Imatinib]], [[Infliximab Injection]], [[Interferon Alfa-2a and Alfa-2b Injection]], [[Interferon Alfacon-1 Injection]], [[Interferon beta-1a Intramuscular Injection]], [[Interferon Beta-1b Injection]], [[Interferon Gamma-1b Injection]], [[Lamivudine]], [[Latanoprost]], [[Leflunomide]], [[Letrozole]], [[Leuprolide]], [[Lovastatin]], [[Methimazole]], [[Methylergonovine]], [[Methylprednisolone]], [[Mifepristone]], [[Natalizumab injection ]], [[Ofloxacin ]], [[Paclitaxel]], [[Peginterferon alfa-2a]], [[Prednisone]], [[Pyrazinamide]], [[Quinupristin]] [[dalfopristin]], [[Ribavirin]], [[Rofecoxib]], [[Rosiglitazone]], [[Rosuvastatin]], [[Sunitinib ]], [[Tadalafil ]], [[Tamsulosin ]], [[Telbivudine ]], [[Temozolomide ]], [[Terbutaline]], [[Teriparatide]], [[Tiotropium]], [[Torsemide]], [[Valganciclovir]], [[Valsartan]], [[Vancomycin]], [[Vinblastine]], [[Vincristine]], [[Zalcitabine]], [[Ziprasidone]], [[Zolmitriptan]], [[Zolpidem]],
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| [[Hyperparathyroidism]],[[Primary hyperparathyroidism]]
|bgcolor="Beige"| [[Hyperparathyroidism]], [[Primary hyperparathyroidism]]
|-  
|-  
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Ulcerative colitis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Fairbanks disease]],[[Familial Mediterranean fever]],[[Mitochondrial trifunctional protein deficiency]],[[Osteogenesis imperfecta]]
|bgcolor="Beige"| [[Fairbanks disease]], [[Familial Mediterranean fever]], [[Mitochondrial trifunctional protein deficiency]], [[Osteogenesis imperfecta]], [[Hereditary multiple exostoses]], [[Recessive multiple epiphyseal dysplasia]], [[Farber disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Erdheim-Chester disease]], [[Leukemia]], [[Lymphangiomatosis]], [[Multiple myeloma]], [[Phlebitis]], [[Phlegmasia cerulea dolens]], [[Thrombocytosis]], [[Acute lymphoblastic leukemia]], [[Acute myeloid leukemia]], [[Acute promyelocytic leukemia]], [[Cholesterol Embolism]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"|
'''Bacterial : ''' [[Cellulitis]], [[Q Fever]], [[Lassa Fever]], [[Lemierre's Syndrome]], [[Leptospirosis]]
 
'''Viral : ''' [[Parvovirus B19]], [[Poliomyelitis]], [[Rocky Mountain spotted fever]], [[Acquired Immune Deficiency Syndrome]], [[Coxsackie B]],
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
| '''Musculoskeletal / Ortho'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Athlete's foot]], [[Baker's cyst]], [[Bone tumor]], [[Buerger's disease]], [[Chondroblastoma]], [[Chondromalacia patellae]], [[Chondrosarcoma]], [[Gout]], [[Hereditary multiple exostoses]], [[Ledderhose's disease]], [[Legg-Calve-Perthes syndrome]], [[Morton's toe]], [[Myofascial Pain Syndrome]], [[Myositis ossificans]], [[Osteochondrosis]], [[Paget's disease of bone]], [[Pes anserinus]], [[Pigmented villonodular synovitis]], [[Prepatellar bursitis]], [[Recessive multiple epiphyseal dysplasia]], [[Retropatellar Pain Syndrome]], [[Sciatica]], [[Synovial osteochondromatosis]], [[Tenosynovitis]], [[Erythromelagia]], [[Ewing's sarcoma]], [[Giant cell tumor of bone]], [[Osteoporosis]], [[Still's disease]], [[Fairbanks disease]], [[Osteogenesis imperfecta]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Amyotrophic Lateral Sclerosis]], [[Anterior spinal artery syndrome]], [[Erythromelagia]], [[Meralgia paraesthetica]], [[Peripheral Neuropathy]], [[Restless Leg Syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Nutritional / Metabolic'''
| '''Nutritional / Metabolic'''
|bgcolor="Beige"| [[Acute Intermittent Porphyria]],[[Farber disease]],[[Glycogen storage disease type V]],[[Hypercalcemia]],[[Mucopolysaccharidosis]],[[Osteomalacia]]
|bgcolor="Beige"| [[Acute Intermittent Porphyria]], [[Farber disease]], [[Glycogen storage disease type V]], [[Hypercalcemia]], [[Mucopolysaccharidosis]], [[Osteomalacia]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]],[[Acute myeloid leukemia]],[[Acute promyelocytic leukemia]],[[Ewing's sarcoma]],[[Giant cell tumor of bone]],[[Osteochondroma]],[[Osteoma]],[[Osteosarcoma]]
|bgcolor="Beige"| [[Acute lymphoblastic leukemia]], [[Acute myeloid leukemia]], [[Acute promyelocytic leukemia]], [[Ewing's sarcoma]], [[Giant cell tumor of bone]], [[Osteochondroma]], [[Osteoma]], [[Osteosarcoma]], [[Leukemia]], [[Lymphangiomatosis]], [[Chondroblastoma]], [[Chondrosarcoma]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Opthalmologic'''
| '''Opthalmologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Behect's disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
| '''Renal / Electrolyte'''
|bgcolor="Beige"| [[Hypercalcemia]]
|bgcolor="Beige"| [[Hypercalcemia]], [[Hypocalcemia]], [[Hypokalemia]], [[Hyponatremia]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''
| '''Rheum / Immune / Allergy'''
|bgcolor="Beige"|
|bgcolor="Beige"|
'''Rheumatology :''' [[Ankylosing Spondylitis]],[[Behect's disease]],[[Caplan's Syndrome]],[[Fibromyalgia]],[[Osteoarthritis]],[[Osteoporosis]],[[Polymyalgia Rheumatica]],[[Rheumatoid arthritis]],[[Still's disease]], [[Gout]]
'''Rheumatology :''' [[Ankylosing Spondylitis]], [[Behcet's disease]], [[Caplan's Syndrome]], [[Fibromyalgia]], [[Osteoarthritis]], [[Osteoporosis]], [[Polymyalgia Rheumatica]], [[Rheumatoid arthritis]], [[Still's disease]], [[Gout]]


''' Immunology :''' [[Systemic lupus erythematosus]],[[Ulcerative colitis]],[[Vasculitis]],[[Graft-versus-host disease]],[[Familial Mediterranean fever]]
''' Immunology :''' [[Systemic lupus erythematosus]], [[Ulcerative colitis]], [[Vasculitis]], [[Graft-versus-host disease]], [[Familial Mediterranean fever]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|bgcolor="Beige"| [[Phantom pain]]
|bgcolor="Beige"| [[Phantom pain]]
|-
|-
|}  
|}
 
===Causes in Alphabetical Order===
{{MultiCol}}
 
*[[Abatacept Injection]]
 
*[[Acebutolol]]
 
*[[Acitretin]]
 
*[[Acquired Immune Deficiency Syndrome]]
 
*[[Acute Intermittent Porphyria]]
 
*[[Acute lymphoblastic leukemia]]
 
*[[Acute myeloid leukemia]]
 
*[[Acute promyelocytic leukemia]]
 
*[[Aldesleukin]]
 
*[[Alendronate]]
 
*[[Allopurinol]]
 
*[[Amikacin Sulfate Injection]]
 
*[[Amyotrophic Lateral Sclerosis]]
 
*[[Anagrelide]]
 
*[[Anastrozole]]
 
*[[Ankylosing Spondylitis]]
 
*[[Anterior spinal artery syndrome]]
 
*[[Aortoiliac occlusive disease]]
 
*[[Aripiprazole]]
 
*[[Atazanavir]]
 
*[[Atenolol]]
 
*[[Athlete's foot]]
 
*[[Atorvastatin]]
 
*[[Baker's cyst]]
 
*[[Behcet's disease]]
 
*[[Bevacizumab Injection]]
 
*[[Bone tumor]]
 
*[[Bortezomib]]
 
*[[Buerger's disease]]
 
*[[Buspirone]]
 
*[[Capecitabine]]
 
*[[Caplan's Syndrome]]
 
*[[Celecoxib]]
 
*[[Celiac disease]]
 
*[[Cellulitis]]
 
*[[Cholesterol Emboli Syndrome]]
 
*[[Chondroblastoma]]
 
*[[Chondromalacia patellae]]
 
*[[Chondrosarcoma]]
 
*[[Clofarabine Injection]]
 
*[[Clonazepam]]
 
*[[Clopidogrel]]
 
*[[Cortisol]]
 
*[[Coxsackie B]]
 
*[[Darbepoetin Alfa Injection]]
 
*[[Deep Vein Thrombosis]]
 
*[[Docetaxel]]
 
*[[Epoetin Alfa Injection]]
 
*[[Erdheim-Chester disease]]
 
*[[Erythromelagia]]
 
*[[Ethacrynic Acid]]
 
*[[Etidronate]]
 
*[[Ewing's sarcoma]]
 
*[[Ezetimibe]]
 
*[[Fairbanks disease]]
 
*[[Familial Mediterranean fever]]
 
*[[Farber disease]]
 
*[[Fenofibrate]]
 
{{ColBreak}}
 
*[[Fibromyalgia]]
 
*[[Filgrastim]]
 
*[[Fluvastatin]]
 
*[[Gabapentin]]
 
*[[Galantamine]]
 
*[[Giant cell tumor of bone]]
 
*[[Glatiramer Injection]]
 
*[[Glycogen storage disease type V]]
 
*[[Gout]]
 
*[[Graft-versus-host disease]]
 
*[[Hereditary multiple exostoses]]
 
*[[Hypercalcemia]]
 
*[[Hypercalcemia]]
 
*[[Hyperparathyroidism]]
 
*[[Hypocalcemia]]
 
*[[Hypokalemia]]
 
*[[Hyponatremia]]
 
*[[Ibandronate]]
 
*[[Iloprost]]
 
*[[Imatinib]]
 
*[[Infliximab Injection]]
 
*[[Interferon Alfa-2a and Alfa-2b Injection]]
 
*[[Interferon Alfacon-1 Injection]]
 
*[[Interferon beta-1a Intramuscular Injection]]
 
*[[Interferon Beta-1b Injection]]
 
*[[Interferon Gamma-1b Injection]]
 
*[[Lamivudine]]
 
*[[Lassa Fever]]
 
*[[Latanoprost]]
 
*[[Ledderhose's disease]]
 
*[[Leflunomide]]
 
*[[Legg-Calve-Perthes syndrome]]
 
*[[Lemierre's Syndrome]]
 
*[[Letrozole]]
 
*[[Leukemia]]
 
*[[Leuprolide]]
 
*[[Lovastatin]]


*[[Lymphangiomatosis]]


*[[Meralgia paraesthetica]]


In alphabetical order: <ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref>
*[[Methimazole]]


* Arterial [[thromboembolism]]
*[[Methylergonovine Oral]]
* [[Arthritis]]
 
* Autoimmune vascular disorders such as [[vasculitis]]
*[[Methylprednisolone Oral]]
* [[Baker's cyst]]
 
* [[Cholesterol embolism]]
*[[Mifepristone]]
* Chronic [[venous insufficiency]]
 
* [[Connective tissue disease]]
*[[Mitochondrial trifunctional protein deficiency]]
* [[Coxsackie B]]
 
* [[Deep Vein Thrombosis]] ([[DVT]])
*[[Morton's toe]]
* [[Drug]]s, [[toxin]]s
 
* [[Hypocalcemia]]
*[[Mucopolysaccharidosis]]
* [[Hypokalemia]]
 
* [[Hyponatremia]]
*[[Multiple myeloma]]
* [[Leptospirosis]]
 
* Ligament damage
*[[Myofascial Pain Syndrome]]
* Lumbar canal stenosis or [[spinal stenosis]]
 
* Muscle or tendon strain
*[[Myositis ossificans]]
* [[Night cramps]]
 
* [[Obliterating endarteritis]]
*[[Natalizumab injection]]
* [[Peripheral neuropathy]]
 
* [[Peripheral vascular disease]]
*[[Ofloxacin]]
* Plexopathy
 
* Primary varicosis
*[[Osteoarthritis]]
* [[Radiculopathy]]
 
* [[Restless Leg Syndrome]]
*[[Osteochondroma]]
* [[Venous thromboembolism]] ([[VTE]])
 
*[[Osteochondrosis]]
 
*[[Osteogenesis imperfecta]]
 
*[[Osteoma]]
 
*[[Osteomalacia]]
 
*[[Osteoporosis]]
 
{{ColBreak}}
 
*[[Osteosarcoma]]
 
*[[Paclitaxel]]
 
*[[Paget's disease of bone]]
 
*[[Pain disorder]]
 
*[[Parvovirus B19]]
 
*[[Peg interferon alfa-2a]]
 
*[[Peripheral Arterial Disease]]
 
*[[Peripheral Neuropathy]]
 
*[[Pes anserinus]](leg)
 
*[[Phantom pain]]
 
*[[Phlebitis]]
 
*[[Phlegmasia cerulea dolens]]
 
*[[Pigmented villonodular synovitis]]
 
*[[Poliomyelitis]]
 
*[[Polymyalgia Rheumatica]]
 
*[[Prednisone]]
 
*[[Prepatellar bursitis]]
 
*[[Primary hyperparathyroidism]]
 
*[[Pyrazinamide]]
 
*[[Q Fever]]
 
*[[Quinupristin and dalfopristin injection]]
 
*[[Recessive multiple epiphyseal dysplasia]]
 
*[[Retro patellar Pain Syndrome]]
 
*[[Rheumatoid arthritis]]
 
*[[Ribavirin]]
 
*[[Rocky Mountain spotted fever]]
 
*[[Rofecoxib]]
 
*[[Rosiglitazone]]
 
*[[Rosuvastatin]]
 
*[[Sciatica]]
 
*[[Still's disease]]
 
*[[Sunitinib]]
 
*[[Synovial osteochondromatosis]]
 
*[[Systemic lupus erythematosus]]
 
*[[Tadalafil]]
 
*[[Tamsulosin]]
 
*[[Telbivudine]]
 
*[[Temozolomide]]
 
*[[Tenosynovitis]]
 
*[[Terbutaline]]
 
*[[Teriparatide]]
 
*[[Thrombocytosis]]
 
*[[Thrombophlebitis]]
 
*[[Tiotropium Oral Inhalation]]
 
*[[Torsemide Injection]]
 
*[[Ulcerative colitis]]
 
*[[Valganciclovir]]
 
*[[Valsartan]]
 
*[[Vancomycin]]
 
*[[Varicose veins]]
 
*[[Vasculitis]]
 
*[[Vinblastine]]
 
*[[Vincristine]]
 
*[[Zalcitabine]]
 
*[[Ziprasidone]]
 
*[[Zolmitriptan Nasal]]
 
*[[Zolpidem]]
{{EndMultiCol}}
 
 
 
<ref>Sailer,Christian,Wasner,Susanne.DifferentialDiagnosisPocket.HermosaBeach,CA:BormBruckmeirPublishingLLC,2002:77ISBN1591032016</ref><ref>Kahan,Scott,Smith,EllenG.InAPage:SignsandSymptoms.Malden,Massachusetts:BlackwellPublishing,2004:68ISBN140510368X</ref>


== References ==
== References ==
{{Reflist|2}}
{{Reflist|2}}
{{SIB}}


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[[Category:Musculoskeletal Disease]]
[[Category:Musculoskeletal Disease]]
[[Category:Symptoms]]
[[Category:Signs and symptoms]]
[[Category:Signs and symptoms]]
[[Category:Orthopedics]]
[[Category:Orthopedics]]
[[Category:Grammar]]

Latest revision as of 18:07, 9 June 2015

Leg pain Microchapters

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Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Causes of Leg pain

Differentiating Leg pain from other Symptoms

Natural History, Complications & Prognosis

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History to be Obtained

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Risk calculators and risk factors for Leg pain

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]

Overview

Leg pain is a common non-specific symptom that often has a musculoskeletal, metabolic or drug side effect basis.

Causes

Common Causes


Causes by Organ System

Cardiovascular Aortoiliac occlusive disease, Cholesterol Emboli Syndrome, Deep Vein Thrombosis, Peripheral Arterial Disease, Thrombophlebitis, Varicose veins
Chemical / poisoning No underlying causes
Dermatologic Behcet's disease
Drug Side Effect Abatacept Injection, Acebutolol, Acitretin, Aldesleukin, Alendronate, Allopurinol, Amikacin Sulfate Injection, Anagrelide, Anastrozole, Aripiprazole, Atazanavir, Atenolol, Atorvastatin, Bevacizumab Injection, Bortezomib, Buspirone, Capecitabine, Celecoxib, Celiac disease, Clofarabine Injection, Clonazepam, Clopidogrel, Cortisol, Darbepoetin Alfa, Docetaxel, Epoetin Alfa Injection, Ethacrynic Acid, Etidronate, Ezetimibe, Fenofibrate, Filgrastim, Fluvastatin, Gabapentin, Galantamine, Glatiramer Injection, Ibandronate, Iloprost, Imatinib, Infliximab Injection, Interferon Alfa-2a and Alfa-2b Injection, Interferon Alfacon-1 Injection, Interferon beta-1a Intramuscular Injection, Interferon Beta-1b Injection, Interferon Gamma-1b Injection, Lamivudine, Latanoprost, Leflunomide, Letrozole, Leuprolide, Lovastatin, Methimazole, Methylergonovine, Methylprednisolone, Mifepristone, Natalizumab injection , Ofloxacin , Paclitaxel, Peginterferon alfa-2a, Prednisone, Pyrazinamide, Quinupristin dalfopristin, Ribavirin, Rofecoxib, Rosiglitazone, Rosuvastatin, Sunitinib , Tadalafil , Tamsulosin , Telbivudine , Temozolomide , Terbutaline, Teriparatide, Tiotropium, Torsemide, Valganciclovir, Valsartan, Vancomycin, Vinblastine, Vincristine, Zalcitabine, Ziprasidone, Zolmitriptan, Zolpidem,
Ear Nose Throat No underlying causes
Endocrine Hyperparathyroidism, Primary hyperparathyroidism
Environmental No underlying causes
Gastroenterologic Ulcerative colitis
Genetic Fairbanks disease, Familial Mediterranean fever, Mitochondrial trifunctional protein deficiency, Osteogenesis imperfecta, Hereditary multiple exostoses, Recessive multiple epiphyseal dysplasia, Farber disease
Hematologic Erdheim-Chester disease, Leukemia, Lymphangiomatosis, Multiple myeloma, Phlebitis, Phlegmasia cerulea dolens, Thrombocytosis, Acute lymphoblastic leukemia, Acute myeloid leukemia, Acute promyelocytic leukemia, Cholesterol Embolism
Iatrogenic No underlying causes
Infectious Disease

Bacterial : Cellulitis, Q Fever, Lassa Fever, Lemierre's Syndrome, Leptospirosis

Viral : Parvovirus B19, Poliomyelitis, Rocky Mountain spotted fever, Acquired Immune Deficiency Syndrome, Coxsackie B,

Musculoskeletal / Ortho Athlete's foot, Baker's cyst, Bone tumor, Buerger's disease, Chondroblastoma, Chondromalacia patellae, Chondrosarcoma, Gout, Hereditary multiple exostoses, Ledderhose's disease, Legg-Calve-Perthes syndrome, Morton's toe, Myofascial Pain Syndrome, Myositis ossificans, Osteochondrosis, Paget's disease of bone, Pes anserinus, Pigmented villonodular synovitis, Prepatellar bursitis, Recessive multiple epiphyseal dysplasia, Retropatellar Pain Syndrome, Sciatica, Synovial osteochondromatosis, Tenosynovitis, Erythromelagia, Ewing's sarcoma, Giant cell tumor of bone, Osteoporosis, Still's disease, Fairbanks disease, Osteogenesis imperfecta
Neurologic Amyotrophic Lateral Sclerosis, Anterior spinal artery syndrome, Erythromelagia, Meralgia paraesthetica, Peripheral Neuropathy, Restless Leg Syndrome
Nutritional / Metabolic Acute Intermittent Porphyria, Farber disease, Glycogen storage disease type V, Hypercalcemia, Mucopolysaccharidosis, Osteomalacia
Obstetric/Gynecologic No underlying causes
Oncologic Acute lymphoblastic leukemia, Acute myeloid leukemia, Acute promyelocytic leukemia, Ewing's sarcoma, Giant cell tumor of bone, Osteochondroma, Osteoma, Osteosarcoma, Leukemia, Lymphangiomatosis, Chondroblastoma, Chondrosarcoma
Opthalmologic Behect's disease
Overdose / Toxicity No underlying causes
Psychiatric Pain disorder
Pulmonary No underlying causes
Renal / Electrolyte Hypercalcemia, Hypocalcemia, Hypokalemia, Hyponatremia
Rheum / Immune / Allergy

Rheumatology : Ankylosing Spondylitis, Behcet's disease, Caplan's Syndrome, Fibromyalgia, Osteoarthritis, Osteoporosis, Polymyalgia Rheumatica, Rheumatoid arthritis, Still's disease, Gout

Immunology : Systemic lupus erythematosus, Ulcerative colitis, Vasculitis, Graft-versus-host disease, Familial Mediterranean fever

Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Phantom pain

Causes in Alphabetical Order



[1][2]

References

  1. ↑ Sailer,Christian,Wasner,Susanne.DifferentialDiagnosisPocket.HermosaBeach,CA:BormBruckmeirPublishingLLC,2002:77ISBN1591032016
  2. ↑ Kahan,Scott,Smith,EllenG.InAPage:SignsandSymptoms.Malden,Massachusetts:BlackwellPublishing,2004:68ISBN140510368X


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