Ganglioglioma MRI: Difference between revisions

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==Overview==
==Overview==


* Gangliogliomas share imaging features with other low-grade neoplasms.
==MRI==
* Calcification is a common finding.
Brain MRI may be helpful in the diagnosis of ganglioglioma.
* Usually little or no associated mass effect or evidence of surrounding vasogenic edema.
* In MRI imaging, ganglioglioma may appear as solid or cystic lesions.
* Gangliogliomas have variable manifestations at nonenhanced CT and hypoattenuating mass is the most frequent manifestation.
* MRI T1-weighted images show a hypointense mass.
* Remodeling of the skull may be seen if the neoplasm is located within the peripheral brain.
* MRI T2-weighted and FLAIR images show a well-circumscribed hyperintense mass.
* MRI appearance of gangliogliomas is also variable and nonspecific.
* Ganglioglioma often does not enhance with intravenous gadolinium. However, some tumors have mild diffuse or patchy enhancement without ring appearance.
* In general, the lesions are hypointense to isointense relative to gray matter on T1 weighted images and hyperintense relative to gray matter on T2 weighted images.
* Conventionally they are sharply demarcated, but some are infiltrative and are indistinguishable from diffuse gliomas.
* The frequency of enhancement following intravenous administration of iodinated contrast media is variable (16%–80%) of gangliogliomas.
* Anaplastic ganglioglioma is frequently infiltrative on MRI and is associated with a higher degree of gadolinium enhancement.
* Overall, diagnosis might be suggested by clinical presentation and MRI characteristics, but the definitive diagnosis is only made by histopathological examination of the tumor. Review : <ref name="pmid26948368">{{cite journal| author=Soffietti R, Rudà R, Reardon D| title=Rare glial tumors. | journal=Handb Clin Neurol | year= 2016 | volume= 134 | issue=  | pages= 399-415 | pmid=26948368 | doi=10.1016/B978-0-12-802997-8.00024-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26948368  }} </ref> <ref name="">{{cite book | last = Hayat | first = M. A. | title = Tumors of the central nervous system | publisher = Springer | location = Dordrecht New York | year = 2012 | isbn = 978-94-007-5487-4 }}</ref> <ref name="RaizerNaidich2008">{{cite journal|last1=Raizer|first1=Jeffrey J.|last2=Naidich|first2=Michelle J.|title=Neuronal Tumors|year=2008|pages=435–448|doi=10.1016/B978-012370863-2.50045-2}}</ref>


==References==
==References==
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Latest revision as of 20:35, 2 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

Overview

MRI

Brain MRI may be helpful in the diagnosis of ganglioglioma.

  • In MRI imaging, ganglioglioma may appear as solid or cystic lesions.
  • MRI T1-weighted images show a hypointense mass.
  • MRI T2-weighted and FLAIR images show a well-circumscribed hyperintense mass.
  • Ganglioglioma often does not enhance with intravenous gadolinium. However, some tumors have mild diffuse or patchy enhancement without ring appearance.
  • Conventionally they are sharply demarcated, but some are infiltrative and are indistinguishable from diffuse gliomas.
  • Anaplastic ganglioglioma is frequently infiltrative on MRI and is associated with a higher degree of gadolinium enhancement.
  • Overall, diagnosis might be suggested by clinical presentation and MRI characteristics, but the definitive diagnosis is only made by histopathological examination of the tumor. Review : [1] [2] [3]

References

  1. Soffietti R, Rudà R, Reardon D (2016). "Rare glial tumors". Handb Clin Neurol. 134: 399–415. doi:10.1016/B978-0-12-802997-8.00024-4. PMID 26948368.
  2. Hayat, M. A. (2012). Tumors of the central nervous system. Dordrecht New York: Springer. ISBN 978-94-007-5487-4.
  3. Raizer, Jeffrey J.; Naidich, Michelle J. (2008). "Neuronal Tumors": 435–448. doi:10.1016/B978-012370863-2.50045-2.


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