Pertussis cost-effectiveness of therapy: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{CMG}} ; {{AE}} {{ADI}} {{LRO}} | |||
{{Pertussis}} | {{Pertussis}} | ||
==Cost Effectiveness of Therapy== | ==Cost Effectiveness of Therapy== | ||
*Given the morbidity of of Pertussis, the cost-effectiveness of treatment is substantial. | |||
**A retrospective assessment of medical costs of confirmed pertussis in 936 adults in Massachusetts during 1998 to 2000, and a prospective assessment of nonmedical costs in 203 adults during 2001 to 2003 indicated that the mean medical and nonmedical cost per case was $326 and $447, respectively, for a societal cost of $773.<ref name="urlNational Guideline Clearinghouse | Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. Recommendations of the Advisory Committee on Immunization Practices (ACIP).">{{cite web |url=http://guideline.gov/content.aspx?id=12632 |title=National Guideline Clearinghouse | Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. Recommendations of the Advisory Committee on Immunization Practices (ACIP). |format= |work= |accessdate=}}</ref> | |||
**If the cost of antimicrobials to treat contacts and the cost of personal time were included, the societal cost could be as high as $1,952 per adult case.<ref name="urlNational Guideline Clearinghouse | Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. Recommendations of the Advisory Committee on Immunization Practices (ACIP).">{{cite web |url=http://guideline.gov/content.aspx?id=12632 |title=National Guideline Clearinghouse | Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. Recommendations of the Advisory Committee on Immunization Practices (ACIP). |format= |work= |accessdate=}}</ref> | |||
==Cost Effectiveness of Vaccination== | ==Cost Effectiveness of Vaccination== | ||
Cost-benefit and cost-effectiveness analyses of adult Tdap vaccination have varied in their results. When discrepancies in the models were addressed, an adult Tdap vaccination program was cost-effective when incidence of pertussis exceeded 120 cases per 100,000 population, using a benchmark of $50,000 per quality-adjusted life year saved. | *Cost-benefit and cost-effectiveness analyses of adult Tdap vaccination have varied in their results. When discrepancies in the models were addressed, an adult Tdap vaccination program was cost-effective when incidence of pertussis exceeded 120 cases per 100,000 population, using a benchmark of $50,000 per quality-adjusted life year saved. <ref name= "PM17296470">{{cite journal |vauthors=Lee GM, Murphy TV, Lett S, Cortese MM, Kretsinger K, Schauer S, Lieu TA |title=Cost effectiveness of pertussis vaccination in adults |journal=Am J Prev Med |volume=32 |issue=3 |pages=186–193 |year=2007 |pmid=17296470 |doi=10.1016/j.amepre.2006.10.016 |url=}}</ref> | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | |||
[[Category:Bacterial diseases]] | |||
[[Category:Pediatrics]] | |||
[[Category:Infectious diseases]] | |||
[[Category:Emergency medicine]] | |||
[[Category:Pulmonology]] | |||
[[Category:Needs overview]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 17:47, 7 January 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2] Luke Rusowicz-Orazem, B.S.
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Cost Effectiveness of Therapy
- Given the morbidity of of Pertussis, the cost-effectiveness of treatment is substantial.
- A retrospective assessment of medical costs of confirmed pertussis in 936 adults in Massachusetts during 1998 to 2000, and a prospective assessment of nonmedical costs in 203 adults during 2001 to 2003 indicated that the mean medical and nonmedical cost per case was $326 and $447, respectively, for a societal cost of $773.[1]
- If the cost of antimicrobials to treat contacts and the cost of personal time were included, the societal cost could be as high as $1,952 per adult case.[1]
Cost Effectiveness of Vaccination
- Cost-benefit and cost-effectiveness analyses of adult Tdap vaccination have varied in their results. When discrepancies in the models were addressed, an adult Tdap vaccination program was cost-effective when incidence of pertussis exceeded 120 cases per 100,000 population, using a benchmark of $50,000 per quality-adjusted life year saved. [2]
References
- ↑ 1.0 1.1 "National Guideline Clearinghouse | Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. Recommendations of the Advisory Committee on Immunization Practices (ACIP)".
- ↑ Lee GM, Murphy TV, Lett S, Cortese MM, Kretsinger K, Schauer S, Lieu TA (2007). "Cost effectiveness of pertussis vaccination in adults". Am J Prev Med. 32 (3): 186–193. doi:10.1016/j.amepre.2006.10.016. PMID 17296470.