Cefapirin: Difference between revisions
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{{ | {{Drugbox | ||
| | | Watchedfields = changed | ||
| | | verifiedrevid = 460022704 | ||
| | | IUPAC_name = | ||
| | | image = Cefapirin.png | ||
<!--Clinical data--> | |||
| | | tradename = | ||
| | | Drugs.com = {{drugs.com|international|cefapirin}} | ||
| MedlinePlus = a601206 | |||
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| | |||
| | |||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | ||
| pregnancy_US = B | | pregnancy_US = B | ||
| pregnancy_category = | | pregnancy_category = | ||
| legal_AU = <!-- Unscheduled / S2 / S4 / S8 --> | | legal_AU = <!-- Unscheduled / S2 / S4 / S8 --> | ||
| legal_UK = <!-- GSL / P / POM / CD --> | | legal_UK = <!-- GSL / P / POM / CD --> | ||
| legal_US = Rx-only | | legal_US = Rx-only | ||
| legal_status = | | legal_status = | ||
| routes_of_administration = [[Intravenous therapy|Intravenous]], [[Intramuscular injection|intramuscular]] | | routes_of_administration = [[Intravenous therapy|Intravenous]], [[Intramuscular injection|intramuscular]] | ||
<!--Pharmacokinetic data--> | |||
| bioavailability = | |||
| protein_bound = | |||
| metabolism = | |||
| elimination_half-life = | |||
| excretion = | |||
<!--Identifiers--> | |||
| CASNo_Ref = {{cascite|correct|CAS}} | |||
| CAS_number_Ref = {{cascite|correct|??}} | |||
| CAS_number = 21593-23-7 | |||
| ATC_prefix = J01 | |||
| ATC_suffix = DB08 | |||
| ATC_supplemental = {{ATCvet|G51|AA05}} {{ATCvet|J51|DB08}} | |||
| PubChem = 30699 | |||
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | |||
| DrugBank = DB01139 | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 28486 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = 89B59H32VN | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D07636 | |||
| ChEBI_Ref = {{ebicite|correct|EBI}} | |||
| ChEBI = 554446 | |||
| ChEMBL_Ref = {{ebicite|correct|EBI}} | |||
| ChEMBL = 1599 | |||
<!--Chemical data--> | |||
| C=17 | H=17 | N=3 | O=6 | S=2 | |||
| molecular_weight = 423.466 g/mol | |||
| smiles = O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)CSc3ccncc3)COC(=O)C)C(=O)O | |||
| InChI = 1/C17H17N3O6S2/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25)/t13-,16-/m1/s1 | |||
| InChIKey = UQLLWWBDSUHNEB-CZUORRHYBF | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C17H17N3O6S2/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25)/t13-,16-/m1/s1 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = UQLLWWBDSUHNEB-CZUORRHYSA-N | |||
}} | }} | ||
__NOTOC__ | |||
{{SI}} | {{SI}} | ||
{{CMG}} | |||
==Overview== | |||
'''Cefapirin''' ([[International Nonproprietary Name|INN]], also spelled '''cephapirin''') is an injectable, first-generation [[cephalosporin]] [[antibiotic]]. It is marketed under the trade name Cefadyl. Production for use in humans has been discontinued in the United States.<ref>http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Overview&DrugName=CEFADYL</ref> | |||
It also has a role in [[veterinary medicine]] as Metricure, an intrauterine preparation, and combined with [[prednisolone]] in Mastiplan, an intramammary preparation. Both are licenced in cattle. | |||
==References== | |||
{{reflist|2}} | |||
{{CephalosporinAntiBiotics}} | {{CephalosporinAntiBiotics}} | ||
[[Category:Cephalosporin antibiotics]] | [[Category:Cephalosporin antibiotics]] | ||
[[Category:Pyridines]] | |||
[[Category:Drug]] | |||
Latest revision as of 12:55, 10 April 2015
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| Clinical data | |
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| AHFS/Drugs.com | International Drug Names |
| MedlinePlus | a601206 |
| Pregnancy category |
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| Routes of administration | Intravenous, intramuscular |
| ATC code | |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C17H17N3O6S2 |
| Molar mass | 423.466 g/mol |
| 3D model (JSmol) | |
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WikiDoc Resources for Cefapirin |
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Most recent articles on Cefapirin |
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Evidence Based Medicine |
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Clinical Trials |
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Ongoing Trials on Cefapirin at Clinical Trials.gov Clinical Trials on Cefapirin at Google
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US National Guidelines Clearinghouse on Cefapirin
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Books |
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News |
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Commentary |
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Definitions |
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Patient resources on Cefapirin Discussion groups on Cefapirin Directions to Hospitals Treating Cefapirin Risk calculators and risk factors for Cefapirin
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Healthcare Provider Resources |
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Causes & Risk Factors for Cefapirin |
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Continuing Medical Education (CME) |
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International |
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Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Cefapirin (INN, also spelled cephapirin) is an injectable, first-generation cephalosporin antibiotic. It is marketed under the trade name Cefadyl. Production for use in humans has been discontinued in the United States.[1]
It also has a role in veterinary medicine as Metricure, an intrauterine preparation, and combined with prednisolone in Mastiplan, an intramammary preparation. Both are licenced in cattle.