Desmoplasia: Difference between revisions
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==Overview== | |||
In [[medicine]], '''desmoplasia''' refers to the formation of [[adhesion]]s or [[fibrosis]] (fibrosis refers to scar tissue) in the vascular stroma of a [[neoplasm]]. It is usually used in the description of [[desmoplastic small round cell tumor]]s. | |||
== | ==Historical Perspective== | ||
Desmoplasia originates from the [[Greek language|Greek]] ''desmos'' (meaning ''fetter'' or ''band'') and ''plasia'' (meaning ''to form''). | |||
==Pathophysiology== | |||
===Gross Pathology=== | |||
Usually you only see desmoplasia with malignant [[neoplasm]]s, which can evoke a [[fibrosis]] response by invading healthy tissue. | |||
===Microscopic Pathology=== | |||
Infiltrating metastatic [[ductal carcinoma]]s of the breast often have a [[scirrous]], [[stellate]] appearance caused by desmoplastic formations. | |||
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Latest revision as of 13:35, 13 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
In medicine, desmoplasia refers to the formation of adhesions or fibrosis (fibrosis refers to scar tissue) in the vascular stroma of a neoplasm. It is usually used in the description of desmoplastic small round cell tumors.
Historical Perspective
Desmoplasia originates from the Greek desmos (meaning fetter or band) and plasia (meaning to form).
Pathophysiology
Gross Pathology
Usually you only see desmoplasia with malignant neoplasms, which can evoke a fibrosis response by invading healthy tissue.
Microscopic Pathology
Infiltrating metastatic ductal carcinomas of the breast often have a scirrous, stellate appearance caused by desmoplastic formations.