Fludroxycortide: Difference between revisions

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Fludroxycortide
Clinical data
Trade names	Cordran, Haelan
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of; administration	Topical
ATC code	D07AC07 (WHO) ;
Legal status
Legal status	UK: POM (Prescription only) ;
Identifiers
	IUPAC name 6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione;
CAS Number	1524-88-5 ;
PubChem CID	15209;
DrugBank	DB00846 ;
ChemSpider	14475 ;
UNII	8EUL29XUQT;
KEGG	D00328 ;
ChEMBL	ChEMBL1201012 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C24H33FO6
Molar mass	436.514 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C1\C=C5/[C@](C)(CC1)[C@@H]2[C@H]([C@H]3[C@](C[C@@H]2O)([C@@]4(OC(O[C@@H]4C3)(C)C)C(=O)CO)C)C[C@@H]5F;
	InChI InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 ; Key:POPFMWWJOGLOIF-XWCQMRHXSA-N ;
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VisualWikitext

Latest revision as of 21:02, 18 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Fludroxycortide (INN, also known as flurandrenolone or flurandrenolide^[1]) is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).^[2]^[3]

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.^[4]^[5]

References

↑ Template:PubChemLink
↑ Drugs.com: Fludroxycortide
↑ Patient.co.uk: Fludroxycortide
↑ Haelan Tape Summary of Product Characteristics
↑ PMID 7215997 (PMID 7215997)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand

[1] Template:PubChemLink

[2] Drugs.com: Fludroxycortide

[3] Patient.co.uk: Fludroxycortide

[4] Haelan Tape Summary of Product Characteristics

[5] PMID 7215997 (PMID 7215997)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand

[1]

[2]

[3]

[4]

[5]

@@ Line 1: / Line 1: @@
-{{drugbox
+{{Drugbox
-| IUPAC_name = 6-fluoro-11,21 dihydroxy-16,17- [(l-methylethylidene) bis (oxy)]-, (6?, 11?, 16?)-  Pregn-4-ene-3,20-dione
+| Verifiedfields = changed
-| image = Fludroxycortide.svg
+| Watchedfields = changed
+| verifiedrevid = 461101313
+| IUPAC_name = 6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione
+| image = Fludroxycortide.png
+<!--Clinical data-->
+| tradename = Cordran, Haelan
+| Drugs.com = {{drugs.com|CONS|fludroxycortide}}
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->
+| legal_UK = POM
+| legal_US = <!-- OTC / Rx-only -->
+| legal_status =
+| routes_of_administration = Topical
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CASNo_Ref = {{cascite|correct|CAS}}
+| CAS_number_Ref = {{cascite|correct|??}}
 | CAS_number = 1524-88-5
 | ATC_prefix = D07
 | ATC_suffix = AC07
 | ATC_supplemental =
 | PubChem = 15209
-| DrugBank = APRD00982
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
-| C=24 | H=33 | F=1 | O=6
+ | DrugBank = DB00846
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 14475
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 8EUL29XUQT
+| KEGG_Ref = {{keggcite|correct|kegg}}
+| KEGG = D00328
+| ChEMBL_Ref = {{ebicite|changed|EBI}}
+| ChEMBL = 1201012
+<!--Chemical data-->
+| C=24 | H=33 | F=1 | O=6
 | molecular_weight = 436.514 g/mol
-| bioavailability =
+| smiles = O=C1\C=C5/[C@](C)(CC1)[C@@H]2[C@H]([C@H]3[C@](C[C@@H]2O)([C@@]4(OC(O[C@@H]4C3)(C)C)C(=O)CO)C)C[C@@H]5F
-| protein_bound =
+| InChI = 1/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
-| metabolism =
+| InChIKey = POPFMWWJOGLOIF-XWCQMRHXBO
-| elimination_half-life =
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
-| excretion =
+| StdInChI = 1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
-| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
-| pregnancy_US = <!-- A / B / C / D / X -->
+| StdInChIKey = POPFMWWJOGLOIF-XWCQMRHXSA-N
-| pregnancy_category =
-| legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->
-| legal_UK = <!-- GSL / P / POM / CD -->
-| legal_US = <!-- OTC / Rx-only -->
-| legal_status =
-| routes_of_administration =
 }}
+__NOTOC__
 {{SI}}
+{{CMG}}
+==Overview==
-'''Floudroxycortide''' (or '''Flurandrenolone''' or '''Flurandrenolide ''') is a synthetic [[steroid]] and is used as an [[anti-inflammatory]] treatment for use on [[skin]] irritations.
+'''Fludroxycortide''' ([[International Nonproprietary Name|INN]], also known as '''flurandrenolone''' or '''flurandrenolide'''<ref>{{PubChemLink|15209}}</ref>) is a synthetic [[topical steroid]] and is used as an [[anti-inflammatory]] treatment for use on [[skin]] irritations. Trade names include '''Haelan''' ([[Typharm]], UK) and '''Cordran''' (by [[Actavis|Watson Pharmaceuticals]], US).<ref>Drugs.com: [http://www.drugs.com/international/fludroxycortide.html Fludroxycortide]</ref><ref>Patient.co.uk: [http://www.patient.co.uk/medicine/Fludroxycortide.htm Fludroxycortide]</ref>
-{{Corticosteroids}}
+Fludroxycortide is available in ointment, cream and as an impregnated tape ('''Haelan tape''', '''Cordran tape'''). Licensed indications in the United Kingdom include recalcitrant [[dermatoses]].<ref>[http://www.typharm.com/typharm/docs/Haelan_Tape_SPC.pdf Haelan Tape Summary of Product Characteristics]</ref><ref>{{cite pmid|7215997}}</ref>
+==References==
+{{Reflist|2}}
-[[Category: Dermatology]]
-{{WH}}
+[[Category:Drug]]
-{{WikiDoc Sources}}
+[[Category:Glucocorticoids]]
+[[Category:Organofluorides]]

Fludroxycortide: Difference between revisions

Latest revision as of 21:02, 18 August 2015

Overview

References

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