Addison's disease causes: Difference between revisions

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{{Addison's disease}}
{{Addison's disease}}


{{CMG}}
{{CMG}} ; {{AE}} {{ADG}}
 
==Overview==
==Overview==
Common causes of Addison's disease include [[autoimmune]], [[tuberculosis]], [[AIDS]], [[CMV]], [[hemorrhage]], [[infarction]], [[sarcoidosis]] and [[infections]].


== Causes <ref>Sailer, Christian, Wasner, Susanne.  Differential Diagnosis Pocket.  Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:14-15</ref> ==
==Causes==
===Life-threatening Causes===
Life-threatening causes of Addison's disease include:
*[[AIDS]] complications
*[[Adrenal]] infarction
*[[Adrenal hemorrhage|Bilateral adrenal hemorrhage]](caused by [[trauma]], [[anticoagulant therapy]], or [[coagulation disorders]]).<ref name="pmid12704285">{{cite journal |vauthors=LaBan MM, Whitmore CE, Taylor RS |title=Bilateral adrenal hemorrhage after anticoagulation prophylaxis for bilateral knee arthroplasty |journal=Am J Phys Med Rehabil |volume=82 |issue=5 |pages=418–20 |year=2003 |pmid=12704285 |doi=10.1097/01.PHM.0000064741.97586.E4 |url=}}</ref>
*Cancerous destruction of the [[adrenal gland]], secondary to infiltrative or [[metastatic disease]].
*[[Tuberculosis|Tubercular]] and [[fungal]] destruction of [[adrenal glands]].
===Common Causes===
Common causes of Addison's disease include:<ref>Sailer, Christian, Wasner, Susanne.  Differential Diagnosis Pocket.  Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:14-15</ref>
* [[Autoimmune]]/[[Idiopathic]]
* [[Tuberculosis]]
* [[AIDS]]
* [[CMV]]
* [[Hemorrhage]]
* [[Infarction]]
* [[Sarcoidosis]]
* [[Infections]]


===Common Causes===
===Less common causes===
*[[Tuberculosis]]
Less common causes of Addison's disease include:
*[[AIDS]]
*[[Autoimmune]]/[[idiopathic]]
*[[CMV]]
*[[Hemorrhage]], [[infarction]]
*[[Sarcoidosis]]
*[[Sarcoidosis]]
*[[Infections]]
*[[Amyloidosis]]
*[[Volume / electrolyte disorders]]
*[[Fungal infections]]
*[[AIDS]] complications
*[[Hemochromatosis]]
*[[Autoimmune polyendocrine syndrome|Polyglandular autoimmune syndromes]]
*[[Adrenoleukodystrophy]]
*Adrenomyelodystrophy
*Congenital factors, including [[hypoplasia]], familial [[glucocorticoid]] insufficiency, and enzyme defect
===Causes by Organ System===
{| style="width:80%; height:100px" border="1"
| style="width:25%" bgcolor="lightsteelblue" ; border="1" | '''Cardiovascular'''
| style="width:75%" bgcolor="beige" ; border="1" | [[Arteritis]], [[Hypotension]], [[Hemorrhage]], [[Infarction]]
|-
|- bgcolor="lightsteelblue"
| '''Chemical / poisoning'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Dermatologic'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Drug Side Effect'''
| bgcolor="beige" | [[Corticosteroid withdrawal]], [[Pasireotide]]
|-
|- bgcolor="lightsteelblue"
| '''Ear Nose Throat'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Endocrine'''
| bgcolor="beige" | [[Adrenal aplasia]] / [[hypoplasia]], [[Adrenal metastases]], After surgery of [[cortisol-secreting tumor]], [[Bilateral adrenalectomy ]] , [[Congenital adrenal hyperplasia]], [[Glucocorticoid deficiency 1]]
|-
|- bgcolor="lightsteelblue"
| '''Environmental'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Gastroenterologic'''
| bgcolor="beige" | [[Hemochromatosis ]]
|-
|- bgcolor="lightsteelblue"
| '''Genetic'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Hematologic'''
| bgcolor="beige" | [[Anticoagulation]], [[Coagulopathy ]] , [[Embolus]], [[Leukemia]], [[Lymphoma ]] , [[Thrombosis]]
|-
|- bgcolor="lightsteelblue"
| '''Iatrogenic'''
| bgcolor="beige" | [[Iatrogenic]], [[Radiation therapy]]
|-
|- bgcolor="lightsteelblue"
| '''Infectious Disease'''
| bgcolor="beige" | [[AIDS]], [[Blastomycosis]], [[CMV]], [[Coccidiomycosis]], [[Cryptococcosis]], [[Histoplasmosis ]] , [[Mycobacterium avium intracellulaire]] ([[MAI]]), [[Sepsis]], [[Syphilis]], [[Toxoplasmosis]], [[Tuberculosis]], [[Waterhouse-Friderichson syndrome ]]
|-
|- bgcolor="lightsteelblue"
| '''Musculoskeletal / Ortho'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Neurologic'''
| bgcolor="beige" | [[Adrenoleukodystrophy]], [[Coma]]
|-
|- bgcolor="lightsteelblue"
| '''Nutritional / Metabolic'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Obstetric/Gynecologic'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Oncologic'''
| bgcolor="beige" | [[Kaposi's sarcoma]], [[Leukemia]], [[Lymphoma ]]
|-
|- bgcolor="lightsteelblue"
| '''Opthalmologic'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Overdose / Toxicity'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Psychiatric'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Pulmonary'''
| bgcolor="beige" | [[Sarcoidosis]],
|-
|- bgcolor="lightsteelblue"
| '''Renal / Electrolyte'''
| bgcolor="beige" | [[Uremia]], [[Waterhouse-Friderichson syndrome ]]
|-
|- bgcolor="lightsteelblue"
| '''Rheum / Immune / Allergy'''
| bgcolor="beige" | [[Autoimmune]], [[Sarcoidosis]]
|-
|- bgcolor="lightsteelblue"
| '''Sexual'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Trauma'''
| bgcolor="beige" | [[Trauma]]
|-
|- bgcolor="lightsteelblue"
| '''Urologic'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Dental'''
| bgcolor="beige" | No underlying causes
|-
|- bgcolor="lightsteelblue"
| '''Miscellaneous'''
| bgcolor="beige" | [[Amyloidosis]], [[Idiopathic]], [[Iatrogenic]], [[Radiation therapy]], [[Surgery]]
|-
|}


===Causes in Alphabetical Order===
===Causes in Alphabetical Order===
{{MultiCol}}
*[[Adrenal aplasia]] / [[hypoplasia]]
*[[Adrenal aplasia]] / hypoplasia  
*[[Adrenal metastases]]
*[[Adrenal metastases]]
*[[Adrenoleukodystrophy]]
*[[AIDS]]
*[[AIDS]]
*[[Amyloidosis]]
*[[Amyloidosis]]
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*[[Cryptococcosis]]
*[[Cryptococcosis]]
*[[Coma]]
*[[Coma]]
*[[Drug withdrawal]]
*[[Corticosteroid]] withdrawal
*[[Drugs ]]
*[[Drugs ]]
*[[Embolus]]
*[[Embolus]]
*[[Fungal]]
*[[Glucocorticoid deficiency 1]]
*[[Glucocorticoid deficiency 1]]
*[[Hemochromatosis ]]
*[[Hemochromatosis ]]
*[[Histoplasmosis ]]
*[[Histoplasmosis ]]
{{ColBreak}}
*[[Hypotension]]
*[[Hypotension]]
*[[Hemorrhage]], [[infarction]]
*[[Hemorrhage]], [[infarction]]
*[[Iatrogenic]]
*[[Iatrogenic]]
*[[Infections]]
*[[Kaposi's sarcoma]]
*[[Kaposi's sarcoma]]
*[[Leukemia]]
*[[Leukemia]]
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*[[Uremia]]
*[[Uremia]]
*[[Waterhouse-Friderichson syndrome ]]
*[[Waterhouse-Friderichson syndrome ]]
{{EndMultiCol}}


==References==
==References==
{{reflist|2}}
{{Reflist|2}}
 
[[Category:Endocrinology]]
[[Category:Disease]]
[[Category:Medical emergencies]]
[[Category:Emergency medicine]]
[[Category:Intensive care medicine]]
[[Category:Needs overview]]


{{WH}}
{{WH}}
{{WS}}
{{WS}}

Latest revision as of 16:38, 11 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Common causes of Addison's disease include autoimmune, tuberculosis, AIDS, CMV, hemorrhage, infarction, sarcoidosis and infections.

Causes

Life-threatening Causes

Life-threatening causes of Addison's disease include:

Common Causes

Common causes of Addison's disease include:[2]

Less common causes

Less common causes of Addison's disease include:

Causes by Organ System

Cardiovascular Arteritis, Hypotension, Hemorrhage, Infarction
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect Corticosteroid withdrawal, Pasireotide
Ear Nose Throat No underlying causes
Endocrine Adrenal aplasia / hypoplasia, Adrenal metastases, After surgery of cortisol-secreting tumor, Bilateral adrenalectomy , Congenital adrenal hyperplasia, Glucocorticoid deficiency 1
Environmental No underlying causes
Gastroenterologic Hemochromatosis
Genetic No underlying causes
Hematologic Anticoagulation, Coagulopathy , Embolus, Leukemia, Lymphoma , Thrombosis
Iatrogenic Iatrogenic, Radiation therapy
Infectious Disease AIDS, Blastomycosis, CMV, Coccidiomycosis, Cryptococcosis, Histoplasmosis , Mycobacterium avium intracellulaire (MAI), Sepsis, Syphilis, Toxoplasmosis, Tuberculosis, Waterhouse-Friderichson syndrome
Musculoskeletal / Ortho No underlying causes
Neurologic Adrenoleukodystrophy, Coma
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Kaposi's sarcoma, Leukemia, Lymphoma
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Sarcoidosis,
Renal / Electrolyte Uremia, Waterhouse-Friderichson syndrome
Rheum / Immune / Allergy Autoimmune, Sarcoidosis
Sexual No underlying causes
Trauma Trauma
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Amyloidosis, Idiopathic, Iatrogenic, Radiation therapy, Surgery

Causes in Alphabetical Order

References

  1. ↑ LaBan MM, Whitmore CE, Taylor RS (2003). "Bilateral adrenal hemorrhage after anticoagulation prophylaxis for bilateral knee arthroplasty". Am J Phys Med Rehabil. 82 (5): 418–20. doi:10.1097/01.PHM.0000064741.97586.E4. PMID 12704285.
  2. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:14-15

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