Porphyria natural history: Difference between revisions
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{{Porphyria}} | {{Porphyria}} | ||
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==Overview== | ==Overview== | ||
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==Complications== | ==Complications== | ||
Patients with hepatic porphyrias (PCT, AIP, HCP, VP) are at increased risk over their life for [[hepatocellular carcinoma]] (primary liver cancer) and may require monitoring. Other typical risk factors for liver cancer need not be present, such as hepatitis B or C, iron overload or alcoholic cirrhosis. | * Patients with hepatic porphyrias (PCT, AIP, HCP, VP) are at increased risk over their life for [[hepatocellular carcinoma]] (primary liver cancer) and may require monitoring. Other typical risk factors for liver cancer need not be present, such as hepatitis B or C, iron overload or alcoholic cirrhosis. | ||
* The neuropathic effects can progress and become severe leading to irreversible neurologic damage | |||
** [[Guillian-Barre]] type syndrome with [[paralysis]] | |||
** [[Bulbar dysfunction]] | |||
** [[Respiratory failure]] | |||
** [[Death]] | |||
==Prognosis== | ==Prognosis== | ||
==References== | ==References== | ||
{{ | {{reflist|2}} | ||
[[Category: | [[Category:Dermatology]] | ||
[[Category:Gastroenterology]] | |||
[[Category:Hematology]] | |||
[[Category:Endocrinology]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Latest revision as of 13:33, 22 July 2016
Porphyria Microchapters |
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Porphyria natural history On the Web |
American Roentgen Ray Society Images of Porphyria natural history |
Risk calculators and risk factors for Porphyria natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Natural History
Complications
- Patients with hepatic porphyrias (PCT, AIP, HCP, VP) are at increased risk over their life for hepatocellular carcinoma (primary liver cancer) and may require monitoring. Other typical risk factors for liver cancer need not be present, such as hepatitis B or C, iron overload or alcoholic cirrhosis.
- The neuropathic effects can progress and become severe leading to irreversible neurologic damage
- Guillian-Barre type syndrome with paralysis
- Bulbar dysfunction
- Respiratory failure
- Death