Psoriasis other diagnostic studies: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Psoriasis}} | {{Psoriasis}} | ||
{{CMG}}; {{AE}}{{HK}} | |||
==Overview== | |||
Skin biopsy may be helpful in the diagnosis of psoriasis. Common findings include perivascular and [[dermal]] [[Inflammatory cells|inflammatory cell]] infiltration, [[vascular]] dilation, and absent [[granular layer]]. | |||
==Other Diagnostic Studies== | |||
===Skin Biopsy=== | |||
Skin biopsy may be helpful in the diagnosis of psoriasis. On an [[H&E stain|hematoxylin and eosin (H&E)]] stain, the following findings may be observed:<ref name="pmid18251745">{{cite journal |vauthors=Werner B, Bresch M, Brenner FM, Lima HC |title=Comparative study of histopathological and immunohistochemical findings in skin biopsies from patients with psoriasis before and after treatment with acitretin |journal=J. Cutan. Pathol. |volume=35 |issue=3 |pages=302–10 |year=2008 |pmid=18251745 |doi=10.1111/j.1600-0560.2007.00800.x |url=}}</ref> | |||
*Perivascular and [[dermal]] [[Inflammatory cells|inflammatory cell]] infiltration | |||
*[[Vascular]] dilation | |||
*Absent [[granular layer]] | |||
*Elongation of [[dermal]] [[Papilla|papillae]] | |||
*Parakeratosis | |||
*Spongiform [[pustules]] of Kogoj (pathognomic of psoriasis) | |||
*Munro's micro abscesses (pathognomic of psoriasis) | |||
*[[Edema]] of [[dermal]] [[papillae]] | |||
*In psoriasis, skin [[biopsy]] of the affected area of skin shows that the [[Epidermis (skin)|epidermal]]/suprapapillary thickness ratio is increased | |||
*[[Basal cell layer]] is expanded | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Dermatology]] | |||
[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Disease]] | |||
Latest revision as of 23:52, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Skin biopsy may be helpful in the diagnosis of psoriasis. Common findings include perivascular and dermal inflammatory cell infiltration, vascular dilation, and absent granular layer.
Other Diagnostic Studies
Skin Biopsy
Skin biopsy may be helpful in the diagnosis of psoriasis. On an hematoxylin and eosin (H&E) stain, the following findings may be observed:[1]
- Perivascular and dermal inflammatory cell infiltration
- Vascular dilation
- Absent granular layer
- Elongation of dermal papillae
- Parakeratosis
- Spongiform pustules of Kogoj (pathognomic of psoriasis)
- Munro's micro abscesses (pathognomic of psoriasis)
- Edema of dermal papillae
- In psoriasis, skin biopsy of the affected area of skin shows that the epidermal/suprapapillary thickness ratio is increased
- Basal cell layer is expanded
References
- ↑ Werner B, Bresch M, Brenner FM, Lima HC (2008). "Comparative study of histopathological and immunohistochemical findings in skin biopsies from patients with psoriasis before and after treatment with acitretin". J. Cutan. Pathol. 35 (3): 302–10. doi:10.1111/j.1600-0560.2007.00800.x. PMID 18251745.