Latest revision as of 21:04, 21 July 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

The incidence and prevalence of ALS are rising globally. More resources should be dedicated to the advancement of care and research of ALS.

Epidemiology and Demographics

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Incidence

The incidence of ALS is around 0.6-3.8 per 100000 person-years.

Prevalance

The prevalence of ALS is between 4.1-8.4 per 100000 person-years.

Age Onset

The median age of onset of ALS is between 51-66 years.

Gender

The male population is more commonly affected by ALS than females.

^[1]

References

↑ Longinetti E, Fang F (2019). "Epidemiology of amyotrophic lateral sclerosis: an update of recent literature". Curr Opin Neurol. 32 (5): 771–776. doi:10.1097/WCO.0000000000000730. PMC 6735526 Check |pmc= value (help). PMID 31361627.

Template:WH Template:WS

[pmid31361627-1] Longinetti E, Fang F (2019). "Epidemiology of amyotrophic lateral sclerosis: an update of recent literature". Curr Opin Neurol. 32 (5): 771–776. doi:10.1097/WCO.0000000000000730. PMC 6735526 Check |pmc= value (help). PMID 31361627.

[1]

@@ Line 2: / Line 2: @@
 {{Amyotrophic lateral sclerosis}}
-{{CMG}}
+{{CMG}}{{AE}}{{MMJ}}
 ==Overview==
-==Epidemiology and Demographics==
+The incidence and prevalence of ALS are rising globally. More resources should be dedicated to the advancement of care and research of ALS.
-*ALS is one of the most common neuromuscular diseases worldwide, and people of all races and ethnic backgrounds are affected.
-*Between 1 to 2 people per 100,000 develop ALS each year . ALS most commonly strikes people between 40 and 60 years of age, but younger and older people can also develop the disease. Men are affected slightly more often than women.
+=Epidemiology and Demographics=
-*Although there have been reports of several "clusters" including three American football players from the San Francisco 49ers, three soccer-playing friends in the south of England, and reports of conjugal (''i.e.'', husband and wife) cases in the south of France<ref name="ALS1">{{cite journal | author = Rachele MG, Mascia V, Tacconi P, Dessi N, Marrosu F | title = Conjugal amyotrophic lateral sclerosis: a report on a couple from Sardinia, Italy.  | journal = Ital J Neurol Sci. | volume = Apr;19 | issue = 2 | pages = 97-100 | year = 1998 | id =  PMID: 10935845}}</ref><ref name="ALS2">{{cite journal | author = Poloni M, Micheli A, Facchetti D, Mai R, Ceriani F | title = Conjugal amyotrophic lateral sclerosis: toxic clustering or change?| journal = Ital J Neurol Sci. | volume = Apr;18 | issue = 2 | pages = 109-12 | year = 1997 | id = PMID: 9239532}}</ref><ref name="ALS3">{{cite journal | author = Camu W, Cadilhac J, Billiard M.  | title = Conjugal amyotrophic lateral sclerosis: a report on two couples from southern France.| journal =  Neurology.  | volume = Mar;44 | issue = 3 Pt 1 | pages = 547-8  | year = 1994 | id = PMID: 8145930}}</ref><ref name="ALS4">{{cite journal | author = Cornblath DR, Kurland LT, Boylan KB, Morrison L, Radhakrishnan K, Montgomery M. | title = Conjugal amyotrophic lateral sclerosis: report of a young married couple.| journal =  Neurology.| volume =  Nov;43 | issue = 11 | pages =  2378-80 | year = 1993 | id = PMID: 8232960}}</ref> <ref name="9couples">{{cite journal | author = Corcia P, Jafari-Schluep HF, Lardillier D, Mazyad H, Giraud P, Clavelou P, Pouget J, Camu W | title = A clustering of conjugal amyotrophic lateral sclerosis in southeastern France. | journal = Neurol. | volume = Apr;60 | issue = 4 | pages = 553-7 | year = 2003 | id = PMID: 12707069}}</ref>, these are statistically plausible chance events. Although many authors consider ALS to be caused by a combination of genetic and environmental risk factors, so far the latter have not been firmly identified, other than a higher risk with increasing age.
+===Incidence===
+*The incidence of ALS is around 0.6-3.8 per 100000 person-years.
+===Prevalance===
+The prevalence of ALS is between 4.1-8.4 per 100000 person-years.
+===Age Onset===
+The median age of onset of ALS is between 51-66 years.
+===Gender===
+The male population is more commonly affected by ALS than females.
+<ref name="pmid31361627">{{cite journal| author=Longinetti E, Fang F| title=Epidemiology of amyotrophic lateral sclerosis: an update of recent literature. | journal=Curr Opin Neurol | year= 2019 | volume= 32 | issue= 5 | pages= 771-776 | pmid=31361627 | doi=10.1097/WCO.0000000000000730 | pmc=6735526 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31361627  }} </ref>
 ==References==
 {{reflist|2}}
+[[Category:Motor neuron disease]]
+[[Category:Neurology]]
+[[Category:Disease]]
 {{WH}}
 {{WS}}

Amyotrophic lateral sclerosis epidemiology and demographics: Difference between revisions