Ulcerative colitis physical examination: Difference between revisions

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__NOTOC__
__NOTOC__
{{Ulcerative colitis}}
{{CMG}}; {{AE}} {{USAMA}}
==Overview==
Ulcerative colitis shows intestinal and extra intestinal findings on physical examination. These include abdominal tenderness, [[fever]], [[pallor]], inflammation of the iris and uvea, skin rash, inflammation of the joints, aphthous ulcers and clubbing of the fingers.<ref name="pmid8596552">{{cite journal| author=Hanauer SB| title=Inflammatory bowel disease. | journal=N Engl J Med | year= 1996 | volume= 334 | issue= 13 | pages= 841-8 | pmid=8596552 | doi=10.1056/NEJM199603283341307 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8596552  }} </ref><ref name="pmid3356884">{{cite journal| author=Prantera C, Davoli M, Lorenzetti R, Pallone F, Marcheggiano A, Iannoni C et al.| title=Clinical and laboratory indicators of extent of ulcerative colitis. Serum C-reactive protein helps the most. | journal=J Clin Gastroenterol | year= 1988 | volume= 10 | issue= 1 | pages= 41-5 | pmid=3356884 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3356884  }} </ref>
== Physical Examination ==
As ulcerative colitis is a [[systemic]] disease, patients may present with [[symptom]]s and [[complication (medicine)|complications]] outside the colon.  These include the following:<ref name="pmid8596552">{{cite journal| author=Hanauer SB| title=Inflammatory bowel disease. | journal=N Engl J Med | year= 1996 | volume= 334 | issue= 13 | pages= 841-8 | pmid=8596552 | doi=10.1056/NEJM199603283341307 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8596552  }} </ref><ref name="pmid9260788">{{cite journal| author=D'Haens G, Geboes K, Peeters M, Baert F, Ectors N, Rutgeerts P| title=Patchy cecal inflammation associated with distal ulcerative colitis: a prospective endoscopic study. | journal=Am J Gastroenterol | year= 1997 | volume= 92 | issue= 8 | pages= 1275-9 | pmid=9260788 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9260788  }} </ref><ref name="pmid10566726">{{cite journal| author=Kim B, Barnett JL, Kleer CG, Appelman HD| title=Endoscopic and histological patchiness in treated ulcerative colitis. | journal=Am J Gastroenterol | year= 1999 | volume= 94 | issue= 11 | pages= 3258-62 | pmid=10566726 | doi=10.1111/j.1572-0241.1999.01533.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10566726  }} </ref><ref name="pmid16151544">{{cite journal| author=Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR et al.| title=Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. | journal=Can J Gastroenterol | year= 2005 | volume= 19 Suppl A | issue=  | pages= 5A-36A | pmid=16151544 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16151544  }} </ref><ref name="pmid28420941">{{cite journal| author=Guan Q, Zhang J| title=Recent Advances: The Imbalance of Cytokines in the Pathogenesis of Inflammatory Bowel Disease. | journal=Mediators Inflamm | year= 2017 | volume= 2017 | issue=  | pages= 4810258 | pmid=28420941 | doi=10.1155/2017/4810258 | pmc=5379128 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28420941  }} </ref>
===General appearance===
*Normal appearance in mild disease
*[[Pallor]] may be noticed
===Vital signs===
*[[Fever]]
*[[Tachycardia]]
*[[Hypotension]]
===Gastrointestinal===
*Normal in mild disease
*[[Abdominal]] [[tenderness ]]when palpated in severe disease
*Blood seen on rectal exam


{{Ulcerative colitis}}
===Eyes===
The ophthalmic physical exam findings may include:
* [[Iritis]] or [[uveitis]], which is inflammation of the iris
* [[Episcleritis]]


{{CMG}}
===Musculoskeletal===


== Overview ==
* Seronegative [[arthritis]], which can be a large-joint [[arthritis|oligoarthritis]] (affecting one or two joints), or may affect many small joints of the hands and feet
* [[Ankylosing spondylitis]], arthritis of the spine
* [[Sacroiliitis]], arthritis of the lower spine


== Physical Examination ==
===Skin===


As ulcerative colitis is a [[systemic]] disease, patients may present with [[symptom]]s and [[complication (medicine)|complications]] outside the colon.  These include the following:
* [[Erythema nodosum]], which is a [[panniculitis]], or inflammation of subcutaneous tissue involving the lower extremities
* [[Pyoderma gangrenosum]], which is a painful ulcerating lesion involving the [[skin]]


* [[Mouth ulcer|aphthous ulcers]] of the mouth
===Other===
* Ophthalmic (involving the eyes):
** [[Iritis]] or [[uveitis]], which is inflammation of the iris
** Episcleritis
* Musculoskeletal:
** Seronegative [[arthritis]], which can be a large-joint [[arthritis|oligoarthritis]] (affecting one or two joints), or may affect many small joints of the hands and feet
** [[Ankylosing spondylitis]], arthritis of the spine
** [[Sacroiliitis]], arthritis of the lower spine
* Cutaneous (related to the skin):
** [[Erythema nodosum]], which is a [[panniculitis]], or inflammation of subcutaneous tissue involving the lower extremities
** [[Pyoderma gangrenosum]], which is a painful ulcerating lesion involving the [[skin]]
* [[Deep venous thrombosis]] and [[pulmonary embolism]]
* [[Deep venous thrombosis]] and [[pulmonary embolism]]
* [[Autoimmune hemolytic anemia]]
* [[Autoimmune hemolytic anemia]]
* [[clubbing]], a deformity of the ends of the fingers
* [[Clubbing]], a deformity of the ends of the fingers
* [[Primary sclerosing cholangitis]], or inflammation of the bile ducts
* [[Primary sclerosing cholangitis]], or inflammation of the bile ducts
* [[Mouth ulcer|Aphthous ulcers]] of the mouth


<div align="center">
<div align="center">
<gallery heights="175" widths="175">
<gallery heights="175" widths="175">
Image:Canker sore.jpg|Patients with '''ulcerative colitis''' can occasionally have [[mouth ulcer|aphthous ulcers]] involving the [[tongue]], [[lips]], [[palate]] and [[pharynx]]
Image:Canker sore.jpg|Patients with '''ulcerative colitis''' can occasionally have [[mouth ulcer|Aphthous ulcers]] involving the [[tongue]], [[lips]], [[palate]] and [[pharynx]]|thumb|By Photographer: User:TheBlunderbuss - Own work. Published under GFDL in English Wiki, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=591677
</gallery>
</gallery>
</div>
</div>


== References ==
== References ==
{{reflist|2}}
{{Reflist|2}}
 
{{WH}}
{{WH}}
{{WS}}


{{WS}}
[[Category:Autoimmune diseases]]
[[Category:Gastroenterology]]
[[Category:Inflammations]]
[[Category:Conditions diagnosed by stool test]]
[[Category:Abdominal pain]]
[[Category:Needs overview]]

Latest revision as of 00:33, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]

Overview

Ulcerative colitis shows intestinal and extra intestinal findings on physical examination. These include abdominal tenderness, fever, pallor, inflammation of the iris and uvea, skin rash, inflammation of the joints, aphthous ulcers and clubbing of the fingers.[1][2]

Physical Examination

As ulcerative colitis is a systemic disease, patients may present with symptoms and complications outside the colon. These include the following:[1][3][4][5][6]

General appearance

  • Normal appearance in mild disease
  • Pallor may be noticed

Vital signs

Gastrointestinal

Eyes

The ophthalmic physical exam findings may include:

Musculoskeletal

Skin

Other

References

  1. 1.0 1.1 Hanauer SB (1996). "Inflammatory bowel disease". N Engl J Med. 334 (13): 841–8. doi:10.1056/NEJM199603283341307. PMID 8596552.
  2. Prantera C, Davoli M, Lorenzetti R, Pallone F, Marcheggiano A, Iannoni C; et al. (1988). "Clinical and laboratory indicators of extent of ulcerative colitis. Serum C-reactive protein helps the most". J Clin Gastroenterol. 10 (1): 41–5. PMID 3356884.
  3. D'Haens G, Geboes K, Peeters M, Baert F, Ectors N, Rutgeerts P (1997). "Patchy cecal inflammation associated with distal ulcerative colitis: a prospective endoscopic study". Am J Gastroenterol. 92 (8): 1275–9. PMID 9260788.
  4. Kim B, Barnett JL, Kleer CG, Appelman HD (1999). "Endoscopic and histological patchiness in treated ulcerative colitis". Am J Gastroenterol. 94 (11): 3258–62. doi:10.1111/j.1572-0241.1999.01533.x. PMID 10566726.
  5. Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR; et al. (2005). "Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology". Can J Gastroenterol. 19 Suppl A: 5A–36A. PMID 16151544.
  6. Guan Q, Zhang J (2017). "Recent Advances: The Imbalance of Cytokines in the Pathogenesis of Inflammatory Bowel Disease". Mediators Inflamm. 2017: 4810258. doi:10.1155/2017/4810258. PMC 5379128. PMID 28420941.

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