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{{Underlinked|date=May 2016}}
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{{Infobox_gene}}
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'''T-complex protein 1 subunit theta''' is a [[protein]] that in humans is encoded by the ''CCT8'' [[gene]].<ref name="pmid7890169">{{cite journal | vauthors = Kubota H, Hynes G, Willison K | title = The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1 | journal = Gene | volume = 154 | issue = 2 | pages = 231–6 |date=Apr 1995 | pmid = 7890169 | pmc =  | doi =10.1016/0378-1119(94)00880-2 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CCT8 chaperonin containing TCP1, subunit 8 (theta)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10694| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Chaperonin containing TCP1, subunit 8 (theta)
| HGNCid = 1623
| Symbol = CCT8
| AltSymbols =; Cctq; D21S246; KIAA0002
| OMIM =
| ECnumber =
| Homologene = 4802
| MGIid = 107183
  | GeneAtlas_image1 = PBB_GE_CCT8_200873_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0042623 |text = ATPase activity, coupled}} {{GNF_GO|id=GO:0051082 |text = unfolded protein binding}}
| Component = {{GNF_GO|id=GO:0005829 |text = cytosol}}
| Process = {{GNF_GO|id=GO:0006457 |text = protein folding}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10694
    | Hs_Ensembl = ENSG00000156261
    | Hs_RefseqProtein = NP_006576
    | Hs_RefseqmRNA = NM_006585
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 21
    | Hs_GenLoc_start = 29350518
    | Hs_GenLoc_end = 29367881
    | Hs_Uniprot = P50990
    | Mm_EntrezGene = 12469
    | Mm_Ensembl = ENSMUSG00000025613
    | Mm_RefseqmRNA = NM_009840
    | Mm_RefseqProtein = NP_033970
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 87372523
    | Mm_GenLoc_end = 87385053
    | Mm_Uniprot = Q3UKQ2
  }}
}}
'''Chaperonin containing TCP1, subunit 8 (theta)''', also known as '''CCT8''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CCT8 chaperonin containing TCP1, subunit 8 (theta)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10694| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CCT8}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27-35 |year= 1995 |pmid= 7584026 |doi=  }}
*{{cite journal  | vauthors=Nomura N, Miyajima N, Sazuka T |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27–35 |year= 1995 |pmid= 7584026 |doi=10.1093/dnares/1.1.27 |display-authors=etal}}
*{{cite journal  | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47-56 |year= 1995 |pmid= 7584028 |doi=  }}
*{{cite journal  | vauthors=Nomura N, Miyajima N, Sazuka T |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47–56 |year= 1995 |pmid= 7584028 |doi=10.1093/dnares/1.1.47 |display-authors=etal}}
*{{cite journal  | author=Kubota H, Hynes G, Willison K |title=The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1. |journal=Gene |volume=154 |issue= 2 |pages= 231-6 |year= 1995 |pmid= 7890169 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Yamazaki M, Ono A, Watanabe K |title=Nucleotide sequence surrounding the locus marker D21S246 on human chromosome 21 |journal=DNA Res. |volume=2 |issue= 4 |pages= 187–9 |year= 1996 |pmid= 8590283 |doi=10.1093/dnares/2.4.187 |display-authors=etal}}
*{{cite journal  | author=Yamazaki M, Ono A, Watanabe K, ''et al.'' |title=Nucleotide sequence surrounding the locus marker D21S246 on human chromosome 21. |journal=DNA Res. |volume=2 |issue= 4 |pages= 187-9 |year= 1996 |pmid= 8590283 |doi=  }}
*{{cite journal  | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
*{{cite journal  | vauthors=Scanlan MJ, Gordan JD, Williamson B |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456–64 |year= 1999 |pmid= 10508479 |doi=10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5  |display-authors=etal}}
*{{cite journal  | author=Scanlan MJ, Gordan JD, Williamson B, ''et al.'' |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma. |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456-64 |year= 1999 |pmid= 10508479 |doi= }}
*{{cite journal  | vauthors=Hynes GM, Willison KR |title=Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin |journal=J. Biol. Chem. |volume=275 |issue= 25 |pages= 18985–94 |year= 2000 |pmid= 10748209 |doi= 10.1074/jbc.M910297199 }}
*{{cite journal  | author=Hynes GM, Willison KR |title=Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin. |journal=J. Biol. Chem. |volume=275 |issue= 25 |pages= 18985-94 |year= 2000 |pmid= 10748209 |doi= 10.1074/jbc.M910297199 }}
*{{cite journal  | vauthors=Hattori M, Fujiyama A, Taylor TD |title=The DNA sequence of human chromosome 21 |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518 |display-authors=etal}}
*{{cite journal  | author=Hattori M, Fujiyama A, Taylor TD, ''et al.'' |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311-9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518 }}
*{{cite journal  | vauthors=Yokota S, Yanagi H, Yura T, Kubota H |title=Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle |journal=Eur. J. Biochem. |volume=268 |issue= 17 |pages= 4664–73 |year= 2001 |pmid= 11532003 |doi=10.1046/j.1432-1327.2001.02393.x  }}
*{{cite journal  | author=Yokota S, Yanagi H, Yura T, Kubota H |title=Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle. |journal=Eur. J. Biochem. |volume=268 |issue= 17 |pages= 4664-73 |year= 2001 |pmid= 11532003 |doi=  }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Imai Y, Soda M, Murakami T |title=A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51901–10 |year= 2004 |pmid= 14532270 |doi= 10.1074/jbc.M309655200 |display-authors=etal}}
*{{cite journal  | author=Imai Y, Soda M, Murakami T, ''et al.'' |title=A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51901-10 |year= 2004 |pmid= 14532270 |doi= 10.1074/jbc.M309655200 }}
*{{cite journal  | vauthors=Bouwmeester T, Bauch A, Ruffner H |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 |display-authors=etal}}
*{{cite journal  | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Rush J, Moritz A, Lee KA |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 |display-authors=etal}}
*{{cite journal  | author=Rush J, Moritz A, Lee KA, ''et al.'' |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94-101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal  | vauthors=Wang L, Zhu YF, Guo XJ |title=A two-dimensional electrophoresis reference map of human ovary |journal=J. Mol. Med. |volume=83 |issue= 10 |pages= 812–21 |year= 2006 |pmid= 16021519 |doi= 10.1007/s00109-005-0676-y |display-authors=etal}}
*{{cite journal  | author=Wang L, Zhu YF, Guo XJ, ''et al.'' |title=A two-dimensional electrophoresis reference map of human ovary. |journal=J. Mol. Med. |volume=83 |issue= 10 |pages= 812-21 |year= 2006 |pmid= 16021519 |doi= 10.1007/s00109-005-0676-y }}
*{{cite journal  | vauthors=Hu YH, Warnatz HJ, Vanhecke D |title=Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins |journal=BMC Genomics |volume=7|pages= 155 |year= 2006 |pmid= 16780588 |doi= 10.1186/1471-2164-7-155  | pmc=1526728 |display-authors=etal}}
*{{cite journal  | author=Hu YH, Warnatz HJ, Vanhecke D, ''et al.'' |title=Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. |journal=BMC Genomics |volume=7 |issue= |pages= 155 |year= 2006 |pmid= 16780588 |doi= 10.1186/1471-2164-7-155 }}
*{{cite journal  | vauthors=Kim SC, Sprung R, Chen Y |title=Substrate and functional diversity of lysine acetylation revealed by a proteomics survey |journal=Mol. Cell |volume=23 |issue= 4 |pages= 607–18 |year= 2006 |pmid= 16916647 |doi= 10.1016/j.molcel.2006.06.026 |display-authors=etal}}
*{{cite journal  | author=Kim SC, Sprung R, Chen Y, ''et al.'' |title=Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. |journal=Mol. Cell |volume=23 |issue= 4 |pages= 607-18 |year= 2006 |pmid= 16916647 |doi= 10.1016/j.molcel.2006.06.026 }}
}}
}}
{{refend}}
{{refend}}
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Latest revision as of 09:20, 30 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

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Ensembl

n/a

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UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

T-complex protein 1 subunit theta is a protein that in humans is encoded by the CCT8 gene.[1][2]


References

  1. ↑ Kubota H, Hynes G, Willison K (Apr 1995). "The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1". Gene. 154 (2): 231–6. doi:10.1016/0378-1119(94)00880-2. PMID 7890169.
  2. ↑ "Entrez Gene: CCT8 chaperonin containing TCP1, subunit 8 (theta)".

External links

Further reading



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