CHAF1A: Difference between revisions

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Latest revision as of 19:33, 8 November 2017

Chromatin assembly factor 1 subunit A is a protein that in humans is encoded by the CHAF1A gene.^[1]^[2]

Function

Chromatin assembly factor I (CAF-1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone tetramers onto replicating DNA in vitro (Kaufman et al., 1995).[supplied by OMIM]^[2]

Interactions

CHAF1A has been shown to interact with:

References

↑ Kaufman PD, Kobayashi R, Kessler N, Stillman B (August 1995). "The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication". Cell. 81 (7): 1105–14. doi:10.1016/S0092-8674(05)80015-7. PMID 7600578.
↑ ^2.0 ^2.1 "Entrez Gene: CHAF1A chromatin assembly factor 1, subunit A (p150)".
↑ ^3.0 ^3.1 Mello JA, Silljé HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G (April 2002). "Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway". EMBO Rep. 3 (4): 329–34. doi:10.1093/embo-reports/kvf068. PMC 1084056. PMID 11897662.
↑ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D. "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
↑ Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I (June 2004). "Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1". Mol. Cell. Biol. 24 (11): 4710–9. doi:10.1128/MCB.24.11.4710-4719.2004. PMC 416397. PMID 15143166.
↑ ^6.0 ^6.1 Reese BE, Bachman KE, Baylin SB, Rountree MR (May 2003). "The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1". Mol. Cell. Biol. 23 (9): 3226–36. doi:10.1128/mcb.23.9.3226-3236.2003. PMC 153189. PMID 12697822.
↑ Lechner MS, Begg GE, Speicher DW, Rauscher FJ (September 2000). "Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential". Mol. Cell. Biol. 20 (17): 6449–65. doi:10.1128/mcb.20.17.6449-6465.2000. PMC 86120. PMID 10938122.

Ridgway P, Almouzni G (2000). "CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair". J. Cell Sci. 113 (15): 2647–58. PMID 10893180.
Verreault A, Kaufman PD, Kobayashi R, Stillman B (1996). "Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4". Cell. 87 (1): 95–104. doi:10.1016/S0092-8674(00)81326-4. PMID 8858152.
Marheineke K, Krude T (1998). "Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle". J. Biol. Chem. 273 (24): 15279–86. doi:10.1074/jbc.273.24.15279. PMID 9614144.
Shibahara K, Stillman B (1999). "Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin". Cell. 96 (4): 575–85. doi:10.1016/S0092-8674(00)80661-3. PMID 10052459.
Murzina N, Verreault A, Laue E, Stillman B (1999). "Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins". Mol. Cell. 4 (4): 529–40. doi:10.1016/S1097-2765(00)80204-X. PMID 10549285.
Moggs JG, Grandi P, Quivy JP, Jónsson ZO, Hübscher U, Becker PB, Almouzni G (2000). "A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage". Mol. Cell. Biol. 20 (4): 1206–18. doi:10.1128/MCB.20.4.1206-1218.2000. PMC 85246. PMID 10648606.
Lechner MS, Begg GE, Speicher DW, Rauscher FJ (2000). "Molecular Determinants for Targeting Heterochromatin Protein 1-Mediated Gene Silencing: Direct Chromoshadow Domain–KAP-1 Corepressor Interaction Is Essential". Mol. Cell. Biol. 20 (17): 6449–65. doi:10.1128/MCB.20.17.6449-6465.2000. PMC 86120. PMID 10938122.
Dong H, Lin W, Zhang CK, Xiong H, Fu G, Jin WR, Chen R, Chen Z, Qi ZT, Huang GM (2001). "Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene". Gene. 264 (2): 187–96. doi:10.1016/S0378-1119(01)00335-3. PMID 11250073.
Mello JA, Silljé HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G (2002). "Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway". EMBO Rep. 3 (4): 329–34. doi:10.1093/embo-reports/kvf068. PMC 1084056. PMID 11897662.
Reese BE, Bachman KE, Baylin SB, Rountree MR (2003). "The Methyl-CpG Binding Protein MBD1 Interacts with the p150 Subunit of Chromatin Assembly Factor 1". Mol. Cell. Biol. 23 (9): 3226–36. doi:10.1128/MCB.23.9.3226-3236.2003. PMC 153189. PMID 12697822.
Morel AP, Sentis S, Bianchin C, Le Romancer M, Jonard L, Rostan MC, Rimokh R, Corbo L (2004). "BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms". J. Cell Sci. 116 (Pt 14): 2929–36. doi:10.1242/jcs.00480. PMID 12771185.
Kitagawa H, Fujiki R, Yoshimura K, Mezaki Y, Uematsu Y, Matsui D, Ogawa S, Unno K, Okubo M, Tokita A, Nakagawa T, Ito T, Ishimi Y, Nagasawa H, Matsumoto T, Yanagisawa J, Kato S (2003). "The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome". Cell. 113 (7): 905–17. doi:10.1016/S0092-8674(03)00436-7. PMID 12837248.
Glinsky GV, Glinskii AB, Stephenson AJ, Hoffman RM, Gerald WL (2004). "Gene expression profiling predicts clinical outcome of prostate cancer". J. Clin. Invest. 113 (6): 913–23. doi:10.1172/JCI20032. PMC 362118. PMID 15067324.
Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I (2004). "Physical and Functional Interaction between the Bloom's Syndrome Gene Product and the Largest Subunit of Chromatin Assembly Factor 1". Mol. Cell. Biol. 24 (11): 4710–9. doi:10.1128/MCB.24.11.4710-4719.2004. PMC 416397. PMID 15143166.
Lehner B, Sanderson CM (2004). "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Sarraf SA, Stancheva I (2004). "Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly". Mol. Cell. 15 (4): 595–605. doi:10.1016/j.molcel.2004.06.043. PMID 15327775.

External links

CHAF1A human gene location in the UCSC Genome Browser.
CHAF1A human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[pmid7600578-1] Kaufman PD, Kobayashi R, Kessler N, Stillman B (August 1995). "The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication". Cell. 81 (7): 1105–14. doi:10.1016/S0092-8674(05)80015-7. PMID 7600578.

[entrez-2] 2.0 ^2.1 "Entrez Gene: CHAF1A chromatin assembly factor 1, subunit A (p150)".

[pmid11897662-3] 3.0 ^3.1 Mello JA, Silljé HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G (April 2002). "Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway". EMBO Rep. 3 (4): 329–34. doi:10.1093/embo-reports/kvf068. PMC 1084056. PMID 11897662.

[pmid17353931-4] Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D. "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

[pmid15143166-5] Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I (June 2004). "Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1". Mol. Cell. Biol. 24 (11): 4710–9. doi:10.1128/MCB.24.11.4710-4719.2004. PMC 416397. PMID 15143166.

[pmid12697822-6] 6.0 ^6.1 Reese BE, Bachman KE, Baylin SB, Rountree MR (May 2003). "The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1". Mol. Cell. Biol. 23 (9): 3226–36. doi:10.1128/mcb.23.9.3226-3236.2003. PMC 153189. PMID 12697822.

[pmid10938122-7] Lechner MS, Begg GE, Speicher DW, Rauscher FJ (September 2000). "Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential". Mol. Cell. Biol. 20 (17): 6449–65. doi:10.1128/mcb.20.17.6449-6465.2000. PMC 86120. PMID 10938122.

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@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Chromatin assembly factor 1 subunit A''' is a [[protein]] that in humans is encoded by the ''CHAF1A'' [[gene]].<ref name="pmid7600578">{{cite journal | vauthors = Kaufman PD, Kobayashi R, Kessler N, Stillman B | title = The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication | journal = Cell | volume = 81 | issue = 7 | pages = 1105–14 | date = August 1995 | pmid = 7600578 | pmc =  | doi = 10.1016/S0092-8674(05)80015-7 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CHAF1A chromatin assembly factor 1, subunit A (p150)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10036| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Function ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Chromatin assembly factor 1, subunit A (p150)
- | HGNCid = 1910
- | Symbol = CHAF1A
- | AltSymbols =; CAF-1; CAF1; CAF1B; CAF1P150; MGC71229; P150
- | OMIM = 601246
- | ECnumber =
- | Homologene = 4003
- | MGIid = 1351331
- | GeneAtlas_image1 = PBB_GE_CHAF1A_203975_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_CHAF1A_203976_s_at_tn.png
- | GeneAtlas_image3 = PBB_GE_CHAF1A_214426_x_at_tn.png
- | Function = {{GNF_GO|id=GO:0003682 |text = chromatin binding}} {{GNF_GO|id=GO:0051082 |text = unfolded protein binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005678 |text = chromatin assembly complex}}
- | Process = {{GNF_GO|id=GO:0006260 |text = DNA replication}} {{GNF_GO|id=GO:0006281 |text = DNA repair}} {{GNF_GO|id=GO:0006335 |text = DNA replication-dependent nucleosome assembly}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006457 |text = protein folding}} {{GNF_GO|id=GO:0006461 |text = protein complex assembly}} {{GNF_GO|id=GO:0007049 |text = cell cycle}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 10036
-    | Hs_Ensembl = ENSG00000167670
-    | Hs_RefseqProtein = NP_005474
-    | Hs_RefseqmRNA = NM_005483
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 19
-    | Hs_GenLoc_start = 4353661
-    | Hs_GenLoc_end = 4394125
-    | Hs_Uniprot = Q13111
-    | Mm_EntrezGene = 27221
-    | Mm_Ensembl = ENSMUSG00000002835
-    | Mm_RefseqmRNA = NM_013733
-    | Mm_RefseqProtein = NP_038761
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 17
-    | Mm_GenLoc_start = 55633805
-    | Mm_GenLoc_end = 55660843
-    | Mm_Uniprot = Q3TU22
-  }}
-}}
-'''Chromatin assembly factor 1, subunit A (p150)''', also known as '''CHAF1A''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CHAF1A chromatin assembly factor 1, subunit A (p150)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10036| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+Chromatin assembly factor I ([[CAF-1]]) is a nuclear complex consisting of p50, p60 ([[CHAF1B]]; MIM 601245), and p150 (CHAF1A) subunits that assembles histone tetramers onto replicating DNA in vitro (Kaufman et al., 1995).[supplied by OMIM]<ref name="entrez" />
-{{PBB_Summary
-| section_title =
-| summary_text = Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: CHAF1A chromatin assembly factor 1, subunit A (p150)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10036| accessdate = }}</ref>
-}}
-==References==
+== Interactions ==
-{{reflist|2}}
-==Further reading==
+CHAF1A has been shown to [[Protein-protein interaction|interact]] with:
+* [[ASF1A]],<ref name = pmid11897662/>
+* [[ASF1B]],<ref name = pmid11897662>{{cite journal | vauthors = Mello JA, Silljé HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G | title = Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway | journal = EMBO Rep. | volume = 3 | issue = 4 | pages = 329–34 | date = April 2002 | pmid = 11897662 | pmc = 1084056 | doi = 10.1093/embo-reports/kvf068 }}</ref><ref name = pmid17353931>{{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Mol. Syst. Biol. | volume = 3 | issue =  | pages = 89 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}</ref>
+* [[Bloom syndrome protein|BLM]],<ref name = pmid15143166>{{cite journal | vauthors = Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I | title = Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1 | journal = Mol. Cell. Biol. | volume = 24 | issue = 11 | pages = 4710–9 | date = June 2004 | pmid = 15143166 | pmc = 416397 | doi = 10.1128/MCB.24.11.4710-4719.2004 }}</ref>
+* [[CBX5 (gene)|CBX5]],<ref name = pmid12697822/><ref name = pmid10938122>{{cite journal | vauthors = Lechner MS, Begg GE, Speicher DW, Rauscher FJ | title = Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential | journal = Mol. Cell. Biol. | volume = 20 | issue = 17 | pages = 6449–65 | date = September 2000 | pmid = 10938122 | pmc = 86120 | doi =  10.1128/mcb.20.17.6449-6465.2000}}</ref> and
+* [[MBD1]].<ref name = pmid12697822>{{cite journal | vauthors = Reese BE, Bachman KE, Baylin SB, Rountree MR | title = The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1 | journal = Mol. Cell. Biol. | volume = 23 | issue = 9 | pages = 3226–36 | date = May 2003 | pmid = 12697822 | pmc = 153189 | doi =  10.1128/mcb.23.9.3226-3236.2003}}</ref>
+== References ==
+{{reflist}}
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Ridgway P, Almouzni G | title = CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair | journal = J. Cell Sci. | volume = 113 | issue = 15 | pages = 2647–58 | year = 2000 | pmid = 10893180 | doi =  }}
-| citations =
+* {{cite journal | vauthors = Verreault A, Kaufman PD, Kobayashi R, Stillman B | title = Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4 | journal = Cell | volume = 87 | issue = 1 | pages = 95–104 | year = 1996 | pmid = 8858152 | doi = 10.1016/S0092-8674(00)81326-4 }}
-*{{cite journal  | author=Ridgway P, Almouzni G |title=CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. |journal=J. Cell. Sci. |volume=113 ( Pt 15) |issue=  |pages= 2647-58 |year= 2000 |pmid= 10893180 |doi=  }}
+* {{cite journal | vauthors = Marheineke K, Krude T | title = Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle | journal = J. Biol. Chem. | volume = 273 | issue = 24 | pages = 15279–86 | year = 1998 | pmid = 9614144 | doi = 10.1074/jbc.273.24.15279 }}
-*{{cite journal  | author=Kaufman PD, Kobayashi R, Kessler N, Stillman B |title=The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. |journal=Cell |volume=81 |issue= 7 |pages= 1105-14 |year= 1995 |pmid= 7600578 |doi=  }}
+* {{cite journal | vauthors = Shibahara K, Stillman B | title = Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin | journal = Cell | volume = 96 | issue = 4 | pages = 575–85 | year = 1999 | pmid = 10052459 | doi = 10.1016/S0092-8674(00)80661-3 }}
-*{{cite journal  | author=Verreault A, Kaufman PD, Kobayashi R, Stillman B |title=Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. |journal=Cell |volume=87 |issue= 1 |pages= 95-104 |year= 1996 |pmid= 8858152 |doi=  }}
+* {{cite journal | vauthors = Murzina N, Verreault A, Laue E, Stillman B | title = Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins | journal = Mol. Cell | volume = 4 | issue = 4 | pages = 529–40 | year = 1999 | pmid = 10549285 | doi = 10.1016/S1097-2765(00)80204-X }}
-*{{cite journal  | author=Marheineke K, Krude T |title=Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle. |journal=J. Biol. Chem. |volume=273 |issue= 24 |pages= 15279-86 |year= 1998 |pmid= 9614144 |doi=  }}
+* {{cite journal | vauthors = Moggs JG, Grandi P, Quivy JP, Jónsson ZO, Hübscher U, Becker PB, Almouzni G | title = A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage | journal = Mol. Cell. Biol. | volume = 20 | issue = 4 | pages = 1206–18 | year = 2000 | pmid = 10648606 | pmc = 85246 | doi = 10.1128/MCB.20.4.1206-1218.2000 }}
-*{{cite journal  | author=Shibahara K, Stillman B |title=Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. |journal=Cell |volume=96 |issue= 4 |pages= 575-85 |year= 1999 |pmid= 10052459 |doi=  }}
+* {{cite journal | vauthors = Lechner MS, Begg GE, Speicher DW, Rauscher FJ | title = Molecular Determinants for Targeting Heterochromatin Protein 1-Mediated Gene Silencing: Direct Chromoshadow Domain–KAP-1 Corepressor Interaction Is Essential | journal = Mol. Cell. Biol. | volume = 20 | issue = 17 | pages = 6449–65 | year = 2000 | pmid = 10938122 | pmc = 86120 | doi = 10.1128/MCB.20.17.6449-6465.2000 }}
-*{{cite journal  | author=Murzina N, Verreault A, Laue E, Stillman B |title=Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. |journal=Mol. Cell |volume=4 |issue= 4 |pages= 529-40 |year= 1999 |pmid= 10549285 |doi=  }}
+* {{cite journal | vauthors = Dong H, Lin W, Zhang CK, Xiong H, Fu G, Jin WR, Chen R, Chen Z, Qi ZT, Huang GM | title = Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene | journal = Gene | volume = 264 | issue = 2 | pages = 187–96 | year = 2001 | pmid = 11250073 | doi = 10.1016/S0378-1119(01)00335-3 }}
-*{{cite journal  | author=Moggs JG, Grandi P, Quivy JP, ''et al.'' |title=A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. |journal=Mol. Cell. Biol. |volume=20 |issue= 4 |pages= 1206-18 |year= 2000 |pmid= 10648606 |doi=  }}
+* {{cite journal | vauthors = Mello JA, Silljé HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G | title = Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway | journal = EMBO Rep. | volume = 3 | issue = 4 | pages = 329–34 | year = 2002 | pmid = 11897662 | pmc = 1084056 | doi = 10.1093/embo-reports/kvf068 }}
-*{{cite journal  | author=Lechner MS, Begg GE, Speicher DW, Rauscher FJ |title=Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential. |journal=Mol. Cell. Biol. |volume=20 |issue= 17 |pages= 6449-65 |year= 2000 |pmid= 10938122 |doi=  }}
+* {{cite journal | vauthors = Reese BE, Bachman KE, Baylin SB, Rountree MR | title = The Methyl-CpG Binding Protein MBD1 Interacts with the p150 Subunit of Chromatin Assembly Factor 1 | journal = Mol. Cell. Biol. | volume = 23 | issue = 9 | pages = 3226–36 | year = 2003 | pmid = 12697822 | pmc = 153189 | doi = 10.1128/MCB.23.9.3226-3236.2003 }}
-*{{cite journal  | author=Dong H, Lin W, Zhang CK, ''et al.'' |title=Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene. |journal=Gene |volume=264 |issue= 2 |pages= 187-96 |year= 2001 |pmid= 11250073 |doi=  }}
+* {{cite journal | vauthors = Morel AP, Sentis S, Bianchin C, Le Romancer M, Jonard L, Rostan MC, Rimokh R, Corbo L | title = BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms | journal = J. Cell Sci. | volume = 116 | issue = Pt 14 | pages = 2929–36 | year = 2004 | pmid = 12771185 | doi = 10.1242/jcs.00480 }}
-*{{cite journal  | author=Mello JA, Silljé HH, Roche DM, ''et al.'' |title=Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. |journal=EMBO Rep. |volume=3 |issue= 4 |pages= 329-34 |year= 2002 |pmid= 11897662 |doi= 10.1093/embo-reports/kvf068 }}
+* {{cite journal | vauthors = Kitagawa H, Fujiki R, Yoshimura K, Mezaki Y, Uematsu Y, Matsui D, Ogawa S, Unno K, Okubo M, Tokita A, Nakagawa T, Ito T, Ishimi Y, Nagasawa H, Matsumoto T, Yanagisawa J, Kato S | title = The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome | journal = Cell | volume = 113 | issue = 7 | pages = 905–17 | year = 2003 | pmid = 12837248 | doi = 10.1016/S0092-8674(03)00436-7 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+* {{cite journal | vauthors = Glinsky GV, Glinskii AB, Stephenson AJ, Hoffman RM, Gerald WL | title = Gene expression profiling predicts clinical outcome of prostate cancer | journal = J. Clin. Invest. | volume = 113 | issue = 6 | pages = 913–23 | year = 2004 | pmid = 15067324 | pmc = 362118 | doi = 10.1172/JCI20032 }}
-*{{cite journal  | author=Reese BE, Bachman KE, Baylin SB, Rountree MR |title=The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. |journal=Mol. Cell. Biol. |volume=23 |issue= 9 |pages= 3226-36 |year= 2003 |pmid= 12697822 |doi=  }}
+* {{cite journal | vauthors = Jiao R, Bachrati CZ, Pedrazzi G, Kuster P, Petkovic M, Li JL, Egli D, Hickson ID, Stagljar I | title = Physical and Functional Interaction between the Bloom's Syndrome Gene Product and the Largest Subunit of Chromatin Assembly Factor 1 | journal = Mol. Cell. Biol. | volume = 24 | issue = 11 | pages = 4710–9 | year = 2004 | pmid = 15143166 | pmc = 416397 | doi = 10.1128/MCB.24.11.4710-4719.2004 }}
-*{{cite journal  | author=Morel AP, Sentis S, Bianchin C, ''et al.'' |title=BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms. |journal=J. Cell. Sci. |volume=116 |issue= Pt 14 |pages= 2929-36 |year= 2004 |pmid= 12771185 |doi= 10.1242/jcs.00480 }}
+* {{cite journal | vauthors = Lehner B, Sanderson CM | title = A Protein Interaction Framework for Human mRNA Degradation | journal = Genome Res. | volume = 14 | issue = 7 | pages = 1315–23 | year = 2004 | pmid = 15231747 | pmc = 442147 | doi = 10.1101/gr.2122004 }}
-*{{cite journal  | author=Kitagawa H, Fujiki R, Yoshimura K, ''et al.'' |title=The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. |journal=Cell |volume=113 |issue= 7 |pages= 905-17 |year= 2003 |pmid= 12837248 |doi=  }}
+* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 33 | pages = 12130–5 | year = 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Glinsky GV, Glinskii AB, Stephenson AJ, ''et al.'' |title=Gene expression profiling predicts clinical outcome of prostate cancer. |journal=J. Clin. Invest. |volume=113 |issue= 6 |pages= 913-23 |year= 2004 |pmid= 15067324 |doi= 10.1172/JCI200420032 }}
+* {{cite journal | vauthors = Sarraf SA, Stancheva I | title = Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly | journal = Mol. Cell | volume = 15 | issue = 4 | pages = 595–605 | year = 2004 | pmid = 15327775 | doi = 10.1016/j.molcel.2004.06.043 }}
-*{{cite journal  | author=Jiao R, Bachrati CZ, Pedrazzi G, ''et al.'' |title=Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1. |journal=Mol. Cell. Biol. |volume=24 |issue= 11 |pages= 4710-9 |year= 2004 |pmid= 15143166 |doi= 10.1128/MCB.24.11.4710-4719.2004 }}
-*{{cite journal  | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315-23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 }}
-*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Sarraf SA, Stancheva I |title=Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. |journal=Mol. Cell |volume=15 |issue= 4 |pages= 595-605 |year= 2004 |pmid= 15327775 |doi= 10.1016/j.molcel.2004.06.043 }}
-}}
 {{refend}}
-{{protein-stub}}
+== External links ==
-{{WikiDoc Sources}}
+* {{UCSC genome browser|CHAF1A}}
+* {{UCSC gene details|CHAF1A}}
+{{gene-19-stub}}

CHAF1A: Difference between revisions

Latest revision as of 19:33, 8 November 2017

Contents

Function

Interactions

References

Further reading

External links

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