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{{ | '''Charged multivesicular body protein 4b''' is a [[protein]] that in humans is encoded by the ''CHMP4B'' [[gene]].<ref name="pmid14678797">{{cite journal | vauthors = Katoh K, Shibata H, Hatta K, Maki M | title = CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms | journal = Arch Biochem Biophys | volume = 421 | issue = 1 | pages = 159–65 |date=Dec 2003 | pmid = 14678797 | pmc = | doi =10.1016/j.abb.2003.09.038 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CHMP4B chromatin modifying protein 4B| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=128866| accessdate = }}</ref> | ||
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==References== | ==References== | ||
{{reflist| | {{reflist}} | ||
==External links== | |||
* {{UCSC gene info|CHMP4A}} | |||
* {{UCSC gene info|CHMP4B}} | |||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | author=Deloukas P | *{{cite journal | author=Deloukas P |title=The DNA sequence and comparative analysis of human chromosome 20 |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a |name-list-format=vanc| author2=Matthews LH | author3=Ashurst J | display-authors=3 | last4=Burton | first4=J. | last5=Gilbert | first5=J. G. R. | last6=Jones | first6=M. | last7=Stavrides | first7=G. | last8=Almeida | first8=J. P. | last9=Babbage | first9=A. K. }} | ||
*{{cite journal | author=Strausberg RL | *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | ||
*{{cite journal | author=Katoh K | *{{cite journal | author=Katoh K |title=The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting |journal=J. Biol. Chem. |volume=278 |issue= 40 |pages= 39104–13 |year= 2003 |pmid= 12860994 |doi= 10.1074/jbc.M301604200 |name-list-format=vanc| author2=Shibata H | author3=Suzuki H | display-authors=3 | last4=Nara | first4=A | last5=Ishidoh | first5=K | last6=Kominami | first6=E | last7=Yoshimori | first7=T | last8=Maki | first8=M }} | ||
*{{cite journal | author=Strack B | *{{cite journal | author=Strack B |title=AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding |journal=Cell |volume=114 |issue= 6 |pages= 689–99 |year= 2003 |pmid= 14505569 |doi=10.1016/S0092-8674(03)00653-6 |name-list-format=vanc| author2=Calistri A | author3=Craig S | display-authors=3 | last4=Popova | first4=Elena | last5=Göttlinger | first5=Heinrich G }} | ||
*{{cite journal | author=von Schwedler UK | *{{cite journal | author=von Schwedler UK |title=The protein network of HIV budding |journal=Cell |volume=114 |issue= 6 |pages= 701–13 |year= 2003 |pmid= 14505570 |doi=10.1016/S0092-8674(03)00714-1 |name-list-format=vanc| author2=Stuchell M | author3=Müller B | display-authors=3 | last4=Ward | first4=Diane M. | last5=Chung | first5=Hyo-Young | last6=Morita | first6=Eiji | last7=Wang | first7=Hubert E. | last8=Davis | first8=Thaylon | last9=He | first9=Gong-Ping }} | ||
*{{cite journal | author=Martin-Serrano J | *{{cite journal | author=Martin-Serrano J |title=Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 21 |pages= 12414–9 |year= 2003 |pmid= 14519844 |doi= 10.1073/pnas.2133846100 | pmc=218772 |name-list-format=vanc| author2=Yarovoy A | author3=Perez-Caballero D | display-authors=3 | last4=Bieniasz | first4=PD }} | ||
*{{cite journal | | *{{cite journal | vauthors=Peck JW, Bowden ET, Burbelo PD |title=Structure and function of human Vps20 and Snf7 proteins |journal=Biochem. J. |volume=377 |issue= Pt 3 |pages= 693–700 |year= 2004 |pmid= 14583093 |doi= 10.1042/BJ20031347 | pmc=1223912 }} | ||
*{{cite journal | author=Sharma M |title=Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes |journal=J. Cell Biol. |volume=164 |issue= 6 |pages= 923–33 |year= 2004 |pmid= 15007060 |doi= 10.1083/jcb.200312018 | pmc=2172283 |name-list-format=vanc| author2=Pampinella F | author3=Nemes C | display-authors=3 | last4=Benharouga | first4=M | last5=So | first5=J | last6=Du | first6=K | last7=Bache | first7=KG | last8=Papsin | first8=B | last9=Zerangue | first9=N }} | |||
*{{cite journal | author=Sharma M | *{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }} | ||
*{{cite journal | author=Gerhard DS | *{{cite journal | author=Yorikawa C |title=Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting |journal=Biochem. J. |volume=387 |issue= Pt 1 |pages= 17–26 |year= 2005 |pmid= 15511219 |doi= 10.1042/BJ20041227 | pmc=1134928 |name-list-format=vanc| author2=Shibata H | author3=Waguri S | display-authors=3 | last4=Hatta | first4=Kazumi | last5=Horii | first5=Mio | last6=Katoh | first6=Keiichi | last7=Kobayashi | first7=Toshihide | last8=Uchiyama | first8=Yasuo | last9=Maki | first9=Masatoshi }} | ||
*{{cite journal | author=Yorikawa C | *{{cite journal | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-format=vanc| author2=Venkatesan K | author3=Hao T | display-authors=3 | last4=Hirozane-Kishikawa | first4=Tomoko | last5=Dricot | first5=Amélie | last6=Li | first6=Ning | last7=Berriz | first7=Gabriel F. | last8=Gibbons | first8=Francis D. | last9=Dreze | first9=Matija }} | ||
*{{cite journal | author=Rual JF | *{{cite journal | author=Tsang HT |title=A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex |journal=Genomics |volume=88 |issue= 3 |pages= 333–46 |year= 2006 |pmid= 16730941 |doi= 10.1016/j.ygeno.2006.04.003 |name-list-format=vanc| author2=Connell JW | author3=Brown SE | display-authors=3 | last4=Thompson | first4=Amanda | last5=Reid | first5=Evan | last6=Sanderson | first6=Christopher M. }} | ||
*{{cite journal | author=Tsang HT | *{{cite journal | vauthors=Usami Y, Popov S, Göttlinger HG |title=Potent Rescue of Human Immunodeficiency Virus Type 1 Late Domain Mutants by ALIX/AIP1 Depends on Its CHMP4 Binding Site |journal=J. Virol. |volume=81 |issue= 12 |pages= 6614–22 |year= 2007 |pmid= 17428861 |doi= 10.1128/JVI.00314-07 | pmc=1900090 }} | ||
*{{cite journal | | *{{cite journal | author=Shiels A |title=CHMP4B, a Novel Gene for Autosomal Dominant Cataracts Linked to Chromosome 20q |journal=Am. J. Hum. Genet. |volume=81 |issue= 3 |pages= 596–606 |year= 2007 |pmid= 17701905 |doi= 10.1086/519980 | pmc=1950844 |name-list-format=vanc| author2=Bennett TM | author3=Knopf HL | display-authors=3 | last4=Yamada | first4=Koki | last5=Yoshiura | first5=Koh-Ichiro | last6=Niikawa | first6=Norio | last7=Shim | first7=Soomin | last8=Hanson | first8=Phyllis I. }} | ||
*{{cite journal | author=Shiels A | |||
}} | }} | ||
{{refend}} | {{refend}} | ||
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
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Charged multivesicular body protein 4b is a protein that in humans is encoded by the CHMP4B gene.[1][2]
References
- ↑ Katoh K, Shibata H, Hatta K, Maki M (Dec 2003). "CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms". Arch Biochem Biophys. 421 (1): 159–65. doi:10.1016/j.abb.2003.09.038. PMID 14678797.
- ↑ "Entrez Gene: CHMP4B chromatin modifying protein 4B".
External links
- Human CHMP4A genome location and CHMP4A gene details page in the UCSC Genome Browser.
- Human CHMP4B genome location and CHMP4B gene details page in the UCSC Genome Browser.
Further reading
- Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Katoh K, Shibata H, Suzuki H, et al. (2003). "The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting". J. Biol. Chem. 278 (40): 39104–13. doi:10.1074/jbc.M301604200. PMID 12860994.
- Strack B, Calistri A, Craig S, et al. (2003). "AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding". Cell. 114 (6): 689–99. doi:10.1016/S0092-8674(03)00653-6. PMID 14505569.
- von Schwedler UK, Stuchell M, Müller B, et al. (2003). "The protein network of HIV budding". Cell. 114 (6): 701–13. doi:10.1016/S0092-8674(03)00714-1. PMID 14505570.
- Martin-Serrano J, Yarovoy A, Perez-Caballero D, et al. (2003). "Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins". Proc. Natl. Acad. Sci. U.S.A. 100 (21): 12414–9. doi:10.1073/pnas.2133846100. PMC 218772. PMID 14519844.
- Peck JW, Bowden ET, Burbelo PD (2004). "Structure and function of human Vps20 and Snf7 proteins". Biochem. J. 377 (Pt 3): 693–700. doi:10.1042/BJ20031347. PMC 1223912. PMID 14583093.
- Sharma M, Pampinella F, Nemes C, et al. (2004). "Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes". J. Cell Biol. 164 (6): 923–33. doi:10.1083/jcb.200312018. PMC 2172283. PMID 15007060.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Yorikawa C, Shibata H, Waguri S, et al. (2005). "Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting". Biochem. J. 387 (Pt 1): 17–26. doi:10.1042/BJ20041227. PMC 1134928. PMID 15511219.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Tsang HT, Connell JW, Brown SE, et al. (2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003. PMID 16730941.
- Usami Y, Popov S, Göttlinger HG (2007). "Potent Rescue of Human Immunodeficiency Virus Type 1 Late Domain Mutants by ALIX/AIP1 Depends on Its CHMP4 Binding Site". J. Virol. 81 (12): 6614–22. doi:10.1128/JVI.00314-07. PMC 1900090. PMID 17428861.
- Shiels A, Bennett TM, Knopf HL, et al. (2007). "CHMP4B, a Novel Gene for Autosomal Dominant Cataracts Linked to Chromosome 20q". Am. J. Hum. Genet. 81 (3): 596–606. doi:10.1086/519980. PMC 1950844. PMID 17701905.
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