GLTSCR2: Difference between revisions

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{{Infobox_gene}}
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'''Glioma tumor suppressor candidate region gene 2 protein''' is a [[protein]] that in humans is encoded by the ''GLTSCR2'' [[gene]].<ref name="pmid10708517">{{cite journal |vauthors=Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB | title = A transcript map of the chromosome 19q-arm glioma tumor suppressor region | journal = Genomics | volume = 64 | issue = 1 | pages = 44–50 |date=Jun 2000 | pmid = 10708517 | pmc =  | doi = 10.1006/geno.1999.6101 }}</ref><ref name="pmid16971513">{{cite journal |vauthors=Okahara F, Itoh K, Nakagawara A, Murakami M, Kanaho Y, Maehama T | title = Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation | journal = Mol Biol Cell | volume = 17 | issue = 11 | pages = 4888–95 |date=Oct 2006 | pmid = 16971513 | pmc = 1635402 | doi = 10.1091/mbc.E06-04-0301 }}</ref><ref name="pmid17657248">{{cite journal |vauthors=Yim JH, Kim YJ, Ko JH, Cho YE, Kim SM, Kim JY, Lee S, Park JH | title = The putative tumor suppressor gene GLTSCR2 induces PTEN-modulated cell death | journal = Cell Death Differ | volume = 14 | issue = 11 | pages = 1872–9 |date=Oct 2007 | pmid = 17657248 | pmc =  | doi = 10.1038/sj.cdd.4402204 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GLTSCR2 glioma tumor suppressor candidate region gene 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29997| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Glioma tumor suppressor candidate region gene 2
| HGNCid = 4333
| Symbol = GLTSCR2
| AltSymbols =; PICT-1; PICT1
| OMIM = 605691
| ECnumber =
| Homologene = 44130
| MGIid = 2154441
  | Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0008150 |text = biological_process}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 29997
    | Hs_Ensembl = ENSG00000105373
    | Hs_RefseqProtein = NP_056525
    | Hs_RefseqmRNA = NM_015710
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 19
    | Hs_GenLoc_start = 52940613
    | Hs_GenLoc_end = 52952126
    | Hs_Uniprot = Q9NZM5
    | Mm_EntrezGene = 68077
    | Mm_Ensembl = ENSMUSG00000041560
    | Mm_RefseqmRNA = NM_133831
    | Mm_RefseqProtein = NP_598592
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 15096692
    | Mm_GenLoc_end = 15104575
    | Mm_Uniprot = 
  }}
}}
'''Glioma tumor suppressor candidate region gene 2''', also known as '''GLTSCR2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GLTSCR2 glioma tumor suppressor candidate region gene 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29997| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
*{{cite journal  | author=Bruni R, Fineschi B, Ogle WO, Roizman B |title=A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infection. |journal=J. Virol. |volume=73 |issue= 5 |pages= 3810-7 |year= 1999 |pmid= 10196275 |doi= }}
*{{cite journal  |vauthors=Bruni R, Fineschi B, Ogle WO, Roizman B |title=A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infection |journal=J. Virol. |volume=73 |issue= 5 |pages= 3810–7 |year= 1999 |pmid= 10196275 |doi=  | pmc=104158  }}
*{{cite journal | author=Smith JS, Tachibana I, Pohl U, ''et al.'' |title=A transcript map of the chromosome 19q-arm glioma tumor suppressor region. |journal=Genomics |volume=64 |issue= 1 |pages= 44-50 |year= 2000 |pmid= 10708517 |doi= 10.1006/geno.1999.6101 }}
*{{cite journal  |vauthors=Andersen JS, Lyon CE, Fox AH |title=Directed proteomic analysis of the human nucleolus |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 |display-authors=etal}}
*{{cite journal  | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
*{{cite journal  |vauthors=Scherl A, Couté Y, Déon C |title=Functional proteomic analysis of human nucleolus |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 | pmc=133617 |display-authors=etal}}
*{{cite journal  | author=Scherl A, Couté Y, Déon C, ''et al.'' |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100-9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  |vauthors=Okahara F, Ikawa H, Kanaho Y, Maehama T |title=Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein |journal=J. Biol. Chem. |volume=279 |issue= 44 |pages= 45300–3 |year= 2004 |pmid= 15355975 |doi= 10.1074/jbc.C400377200 }}
*{{cite journal  | author=Okahara F, Ikawa H, Kanaho Y, Maehama T |title=Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein. |journal=J. Biol. Chem. |volume=279 |issue= 44 |pages= 45300-3 |year= 2004 |pmid= 15355975 |doi= 10.1074/jbc.C400377200 }}
*{{cite journal  |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Andersen JS, Lam YW, Leung AK |title=Nucleolar proteome dynamics |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 |display-authors=etal}}
*{{cite journal  | author=Andersen JS, Lam YW, Leung AK, ''et al.'' |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77-83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
*{{cite journal  |vauthors=Yim JH, Kim YJ, Cho YE |title=GLTSCR2 sensitizes cells to hypoxic injury without involvement of mitochondrial apoptotic cascades |journal=Pathobiology |volume=74 |issue= 5 |pages= 301–8 |year= 2007 |pmid= 17890897 |doi= 10.1159/000105813 |display-authors=etal}}
*{{cite journal  | author=Okahara F, Itoh K, Nakagawara A, ''et al.'' |title=Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation. |journal=Mol. Biol. Cell |volume=17 |issue= 11 |pages= 4888-95 |year= 2007 |pmid= 16971513 |doi= 10.1091/mbc.E06-04-0301 }}
*{{cite journal  | author=Yim JH, Kim YJ, Cho YE, ''et al.'' |title=GLTSCR2 sensitizes cells to hypoxic injury without involvement of mitochondrial apoptotic cascades. |journal=Pathobiology |volume=74 |issue= 5 |pages= 301-8 |year= 2007 |pmid= 17890897 |doi= 10.1159/000105813 }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 08:48, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Glioma tumor suppressor candidate region gene 2 protein is a protein that in humans is encoded by the GLTSCR2 gene.[1][2][3][4]


References

  1. ↑ Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB (Jun 2000). "A transcript map of the chromosome 19q-arm glioma tumor suppressor region". Genomics. 64 (1): 44–50. doi:10.1006/geno.1999.6101. PMID 10708517.
  2. ↑ Okahara F, Itoh K, Nakagawara A, Murakami M, Kanaho Y, Maehama T (Oct 2006). "Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation". Mol Biol Cell. 17 (11): 4888–95. doi:10.1091/mbc.E06-04-0301. PMC 1635402. PMID 16971513.
  3. ↑ Yim JH, Kim YJ, Ko JH, Cho YE, Kim SM, Kim JY, Lee S, Park JH (Oct 2007). "The putative tumor suppressor gene GLTSCR2 induces PTEN-modulated cell death". Cell Death Differ. 14 (11): 1872–9. doi:10.1038/sj.cdd.4402204. PMID 17657248.
  4. ↑ "Entrez Gene: GLTSCR2 glioma tumor suppressor candidate region gene 2".

Further reading



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