GRIP1 (gene): Difference between revisions

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{{Distinguish|glucocorticoid receptor-interacting protein 1}}
{{PBB_Controls
{{Infobox_gene}}
| update_page = yes
'''[[Glutamate receptor-interacting protein]] 1''' is a [[protein]] that in humans is encoded by the ''GRIP1'' [[gene]].<ref name="pmid10197531">{{cite journal |vauthors=Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R | title = EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains | journal = Neuron | volume = 22 | issue = 3 | pages = 511–24 |date=April 1999 | pmid = 10197531 | pmc =  | doi =10.1016/S0896-6273(00)80706-0  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GRIP1 glutamate receptor interacting protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23426| accessdate = }}</ref>
| require_manual_inspection = no
| update_protein_box = yes
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| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image = PBB_Protein_GRIP1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1m5z.
| PDB = {{PDB2|1m5z}}, {{PDB2|1n7e}}, {{PDB2|1n7f}}, {{PDB2|1p1d}}, {{PDB2|1p1e}}, {{PDB2|1v5q}}
| Name = Glutamate receptor interacting protein 1
| HGNCid = 18708
| Symbol = GRIP1
| AltSymbols =; GRIP
| OMIM = 604597
| ECnumber = 
| Homologene = 12938
| MGIid = 1921303
| GeneAtlas_image1 = PBB_GE_GRIP1_214018_at_tn.png
| Function = {{GNF_GO|id=GO:0003713 |text = transcription coactivator activity}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0030159 |text = receptor signaling complex scaffold activity}} {{GNF_GO|id=GO:0050681 |text = androgen receptor binding}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0045121 |text = lipid raft}} {{GNF_GO|id=GO:0045211 |text = postsynaptic membrane}}
| Process = {{GNF_GO|id=GO:0007242 |text = intracellular signaling cascade}} {{GNF_GO|id=GO:0008104 |text = protein localization}} {{GNF_GO|id=GO:0030521 |text = androgen receptor signaling pathway}} {{GNF_GO|id=GO:0045893 |text = positive regulation of transcription, DNA-dependent}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 23426
    | Hs_Ensembl = ENSG00000155974
    | Hs_RefseqProtein = XP_001133901
    | Hs_RefseqmRNA = XM_001133901
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 65029066
    | Hs_GenLoc_end = 65359192
    | Hs_Uniprot = Q9Y3R0
    | Mm_EntrezGene = 74053
    | Mm_Ensembl = ENSMUSG00000034813
    | Mm_RefseqmRNA = XM_982783
    | Mm_RefseqProtein = XP_987877
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 119222572
    | Mm_GenLoc_end = 119490320
    | Mm_Uniprot = Q6GQT7
  }}
}}
'''Glutamate receptor interacting protein 1''', also known as '''GRIP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GRIP1 glutamate receptor interacting protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23426| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
GRIP1 (gene) has been shown to [[Protein-protein interaction|interact]] with:
{{PBB_Summary
* [[Metabotropic glutamate receptor 3|GRM3]],<ref name=pmid11891216/>
| section_title =  
* [[GRIA2]],<ref name=pmid11891216/>
| summary_text =  
* [[GRIA3]],<ref name=pmid11891216/>
}}
* [[GRIA4]],<ref name="pmid11891216">{{cite journal |vauthors=Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK | title = The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs | journal = J. Biol. Chem. | volume = 277 | issue = 18 | pages = 15221–4 |date=May 2002 | pmid = 11891216 | doi = 10.1074/jbc.C200112200 }}</ref>
* [[GRIK2]],<ref name=pmid11891216/><ref name="pmid12597860">{{cite journal |vauthors=Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V | title = Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP | journal = Neuron | volume = 37 | issue = 4 | pages = 625–38 |date=February 2003 | pmid = 12597860 | pmc = 3314502 | doi = 10.1016/S0896-6273(02)01191-1  }}</ref> and
* [[GRIK3]].<ref name="pmid10896157">{{cite journal |vauthors=Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL | title = GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex | journal = Neuron | volume = 26 | issue = 3 | pages = 603–17 |date=June 2000 | pmid = 10896157 | doi = 10.1016/S0896-6273(00)81198-8 }}</ref>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
*{{cite journal   |vauthors=Irvine RA, Ma H, Yu MC, etal |title=Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length. |journal=Hum. Mol. Genet. |volume=9 |issue= 2 |pages= 267–74 |year= 2000 |pmid= 10607837 |doi=10.1093/hmg/9.2.267 }}
| citations =
*{{cite journal  |vauthors=Teyssier C, Belguise K, Galtier F, Chalbos D |title=Characterization of the physical interaction between estrogen receptor alpha and JUN proteins. |journal=J. Biol. Chem. |volume=276 |issue= 39 |pages= 36361–9 |year= 2001 |pmid= 11477071 |doi= 10.1074/jbc.M101806200 }}
*{{cite journal | author=Brückner K, Pablo Labrador J, Scheiffele P, ''et al.'' |title=EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. |journal=Neuron |volume=22 |issue= 3 |pages= 511-24 |year= 1999 |pmid= 10197531 |doi=  }}
*{{cite journal   |vauthors=Lin SH, Arai AC, Wang Z, etal |title=The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. |journal=Mol. Pharmacol. |volume=60 |issue= 5 |pages= 916–23 |year= 2001 |pmid= 11641419 |doi=  }}
*{{cite journal  | author=Irvine RA, Ma H, Yu MC, ''et al.'' |title=Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length. |journal=Hum. Mol. Genet. |volume=9 |issue= 2 |pages= 267-74 |year= 2000 |pmid= 10607837 |doi=  }}
*{{cite journal   |vauthors=Hirbec H, Perestenko O, Nishimune A, etal |title=The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. |journal=J. Biol. Chem. |volume=277 |issue= 18 |pages= 15221–4 |year= 2002 |pmid= 11891216 |doi= 10.1074/jbc.C200112200 }}
*{{cite journal  | author=Teyssier C, Belguise K, Galtier F, Chalbos D |title=Characterization of the physical interaction between estrogen receptor alpha and JUN proteins. |journal=J. Biol. Chem. |volume=276 |issue= 39 |pages= 36361-9 |year= 2001 |pmid= 11477071 |doi= 10.1074/jbc.M101806200 }}
*{{cite journal  |vauthors=Braithwaite SP, Xia H, Malenka RC |title=Differential roles for NSF and GRIP/ABP in AMPA receptor cycling |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 7096–101 |year= 2002 |pmid= 12011465 |doi= 10.1073/pnas.102156099 | pmc=124534 }}
*{{cite journal | author=Lin SH, Arai AC, Wang Z, ''et al.'' |title=The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. |journal=Mol. Pharmacol. |volume=60 |issue= 5 |pages= 916-23 |year= 2001 |pmid= 11641419 |doi=  }}
*{{cite journal  |vauthors=Kotaja N, Karvonen U, Jänne OA, Palvimo JJ |title=The nuclear receptor interaction domain of GRIP1 is modulated by covalent attachment of SUMO-1 |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 30283–8 |year= 2002 |pmid= 12060666 |doi= 10.1074/jbc.M204768200 }}
*{{cite journal | author=Hirbec H, Perestenko O, Nishimune A, ''et al.'' |title=The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. |journal=J. Biol. Chem. |volume=277 |issue= 18 |pages= 15221-4 |year= 2002 |pmid= 11891216 |doi= 10.1074/jbc.C200112200 }}
*{{cite journal   |vauthors=Min G, Kim H, Bae Y, etal |title=Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators |journal=J. Biol. Chem. |volume=277 |issue= 37 |pages= 34626–33 |year= 2002 |pmid= 12114525 |doi= 10.1074/jbc.M205239200 }}
*{{cite journal  | author=Braithwaite SP, Xia H, Malenka RC |title=Differential roles for NSF and GRIP/ABP in AMPA receptor cycling. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 7096-101 |year= 2002 |pmid= 12011465 |doi= 10.1073/pnas.102156099 }}
*{{cite journal  |vauthors=Coutts AS, MacKenzie E, Griffith E, Black DM |title=TES is a novel focal adhesion protein with a role in cell spreading |journal=J. Cell Sci. |volume=116 |issue= Pt 5 |pages= 897–906 |year= 2003 |pmid= 12571287 |doi=10.1242/jcs.00278  }}
*{{cite journal  | author=Kotaja N, Karvonen U, Jänne OA, Palvimo JJ |title=The nuclear receptor interaction domain of GRIP1 is modulated by covalent attachment of SUMO-1. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 30283-8 |year= 2002 |pmid= 12060666 |doi= 10.1074/jbc.M204768200 }}
*{{cite journal   |vauthors=Charych EI, Yu W, Li R, etal |title=A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain |journal=J. Biol. Chem. |volume=279 |issue= 37 |pages= 38978–90 |year= 2004 |pmid= 15226318 |doi= 10.1074/jbc.M405786200 }}
*{{cite journal | author=Min G, Kim H, Bae Y, ''et al.'' |title=Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators. |journal=J. Biol. Chem. |volume=277 |issue= 37 |pages= 34626-33 |year= 2002 |pmid= 12114525 |doi= 10.1074/jbc.M205239200 }}
*{{cite journal   |vauthors=Sugatani J, Nishitani S, Yamakawa K, etal |title=Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1 |journal=Mol. Pharmacol. |volume=67 |issue= 3 |pages= 845–55 |year= 2005 |pmid= 15557560 |doi= 10.1124/mol.104.007161 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Lin DY, Fang HI, Ma AH, etal |title=Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx |journal=Mol. Cell. Biol. |volume=24 |issue= 24 |pages= 10529–41 |year= 2004 |pmid= 15572661 |doi= 10.1128/MCB.24.24.10529-10541.2004 | pmc=533990 }}
*{{cite journal  | author=Coutts AS, MacKenzie E, Griffith E, Black DM |title=TES is a novel focal adhesion protein with a role in cell spreading. |journal=J. Cell. Sci. |volume=116 |issue= Pt 5 |pages= 897-906 |year= 2003 |pmid= 12571287 |doi=  }}
*{{cite journal  |vauthors=Yang CK, Kim JH, Li H, Stallcup MR |title=Differential use of functional domains by CoCoA in its synergistic coactivator function with β-catenin or GRIP1 |journal=J. Biol. Chem. |volume=281 |issue= 6 |pages= 3389–97 |year= 2006 |pmid= 16344550 |doi= 10.1074/jbc.M510403200  | pmc=1626527 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  |vauthors=Liu PY, Hsieh TY, Chou WY, Huang SM |title=Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains |journal=FEBS J. |volume=273 |issue= 10 |pages= 2172–83 |year= 2006 |pmid= 16649994 |doi= 10.1111/j.1742-4658.2006.05231.x }}
*{{cite journal | author=Charych EI, Yu W, Li R, ''et al.'' |title=A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain. |journal=J. Biol. Chem. |volume=279 |issue= 37 |pages= 38978-90 |year= 2004 |pmid= 15226318 |doi= 10.1074/jbc.M405786200 }}
*{{cite journal   |vauthors=Tsai SJ, Liou YJ, Liao DL, etal |title=No association of GRIP1 gene polymorphisms with schizophrenia in Chinese population |journal=Prog. Neuropsychopharmacol. Biol. Psychiatry |volume=31 |issue= 3 |pages= 752–5 |year= 2007 |pmid= 17303296 |doi= 10.1016/j.pnpbp.2007.01.015 }}
*{{cite journal | author=Sugatani J, Nishitani S, Yamakawa K, ''et al.'' |title=Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1. |journal=Mol. Pharmacol. |volume=67 |issue= 3 |pages= 845-55 |year= 2005 |pmid= 15557560 |doi= 10.1124/mol.104.007161 }}
*{{cite journal | author=Lin DY, Fang HI, Ma AH, ''et al.'' |title=Negative modulation of androgen receptor transcriptional activity by Daxx. |journal=Mol. Cell. Biol. |volume=24 |issue= 24 |pages= 10529-41 |year= 2004 |pmid= 15572661 |doi= 10.1128/MCB.24.24.10529-10541.2004 }}
*{{cite journal  | author=Yang CK, Kim JH, Li H, Stallcup MR |title=Differential use of functional domains by coiled-coil coactivator in its synergistic coactivator function with beta-catenin or GRIP1. |journal=J. Biol. Chem. |volume=281 |issue= 6 |pages= 3389-97 |year= 2006 |pmid= 16344550 |doi= 10.1074/jbc.M510403200 }}
*{{cite journal | author=Scherer SE, Muzny DM, Buhay CJ, ''et al.'' |title=The finished DNA sequence of human chromosome 12. |journal=Nature |volume=440 |issue= 7082 |pages= 346-51 |year= 2006 |pmid= 16541075 |doi= 10.1038/nature04569 }}
*{{cite journal  | author=Liu PY, Hsieh TY, Chou WY, Huang SM |title=Modulation of glucocorticoid receptor-interacting protein 1 (GRIP1) transactivation and co-activation activities through its C-terminal repression and self-association domains. |journal=FEBS J. |volume=273 |issue= 10 |pages= 2172-83 |year= 2006 |pmid= 16649994 |doi= 10.1111/j.1742-4658.2006.05231.x }}
*{{cite journal | author=Tsai SJ, Liou YJ, Liao DL, ''et al.'' |title=No association of GRIP1 gene polymorphisms with schizophrenia in Chinese population. |journal=Prog. Neuropsychopharmacol. Biol. Psychiatry |volume=31 |issue= 3 |pages= 752-5 |year= 2007 |pmid= 17303296 |doi= 10.1016/j.pnpbp.2007.01.015 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{PDB Gallery|geneid=23426}}
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{{gene-12-stub}}

Latest revision as of 20:01, 8 November 2017

Not to be confused with glucocorticoid receptor-interacting protein 1.
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Glutamate receptor-interacting protein 1 is a protein that in humans is encoded by the GRIP1 gene.[1][2]

Interactions

GRIP1 (gene) has been shown to interact with:

References

  1. ↑ Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (April 1999). "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains". Neuron. 22 (3): 511–24. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531.
  2. ↑ "Entrez Gene: GRIP1 glutamate receptor interacting protein 1".
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK (May 2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. 277 (18): 15221–4. doi:10.1074/jbc.C200112200. PMID 11891216.
  4. ↑ Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V (February 2003). "Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP". Neuron. 37 (4): 625–38. doi:10.1016/S0896-6273(02)01191-1. PMC 3314502. PMID 12597860.
  5. ↑ Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (June 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.

Further reading


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