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{{Infobox_gene}}
{{PBB_Controls
'''Glutamate receptor-interacting protein 2''' is a [[protein]] that in humans is encoded by the ''GRIP2'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GRIP2 glutamate receptor interacting protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80852| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
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}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image = PBB_Protein_GRIP2_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1v62.
| PDB = {{PDB2|1v62}}, {{PDB2|1x5r}}
| Name = Glutamate receptor interacting protein 2
| HGNCid = 23841
| Symbol = GRIP2
| AltSymbols =;
| OMIM = 
| ECnumber = 
| Homologene = 16327
| MGIid = 2681173
| GeneAtlas_image1 = PBB_GE_GRIP2_216481_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 80852
    | Hs_Ensembl = ENSG00000144596
    | Hs_RefseqProtein = XP_042936
    | Hs_RefseqmRNA = XM_042936
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 14505623
    | Hs_GenLoc_end = 14556840
    | Hs_Uniprot = Q9C0E4
    | Mm_EntrezGene = 243547
    | Mm_Ensembl = ENSMUSG00000030098
    | Mm_RefseqmRNA = XM_001000130
    | Mm_RefseqProtein = XP_001000130
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 91727016
    | Mm_GenLoc_end = 91748413
    | Mm_Uniprot = 
  }}
}}
'''Glutamate receptor interacting protein 2''', also known as '''GRIP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GRIP2 glutamate receptor interacting protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80852| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
GRIP2 has been shown to [[Protein-protein interaction|interact]] with [[liprin-alpha-1]].<ref name=pmid12923177>{{cite journal |vauthors=Ko J, Na M, Kim S, Lee JR, Kim E | title = Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins | journal = J. Biol. Chem. | volume = 278 | issue = 43 | pages = 42377–85 | date = Oct 2003 | pmid = 12923177 | doi = 10.1074/jbc.M307561200 }}</ref><ref name=pmid12629171>{{cite journal |vauthors=Ko J, Kim S, Valtschanoff JG, Shin H, Lee JR, Sheng M, Premont RT, Weinberg RJ, Kim E | title = Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting | journal = J. Neurosci. | volume = 23 | issue = 5 | pages = 1667–77 | date = Mar 2003 | pmid = 12629171 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
| citation =  
| citations =  
*{{cite journal |vauthors=Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T | title = Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. | journal = DNA Res. | volume = 9 | issue = 3 | pages = 99–106 | year = 2003 | pmid = 12168954 | doi = 10.1093/dnares/9.3.99 }}
*{{cite journal | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99-106 |year= 2003 |pmid= 12168954 |doi= }}
*{{cite journal |vauthors=Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction. | journal = Anal. Biochem. | volume = 236 | issue = 1 | pages = 107–13 | year = 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal |vauthors=Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-Scale Concatenation cDNA Sequencing | journal = Genome Res. | volume = 7 | issue = 4 | pages = 353–8 | year = 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
*{{cite journal |vauthors=Srivastava S, Osten P, Vilim FS, Khatri L, Inman G, States B, Daly C, DeSouza S, Abagyan R, Valtschanoff JG, Weinberg RJ, Ziff EB | title = Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP | journal = Neuron | volume = 21 | issue = 3 | pages = 581–91 | year = 1998 | pmid = 9768844 | doi = 10.1016/S0896-6273(00)80568-1 }}
*{{cite journal | author=Srivastava S, Osten P, Vilim FS, ''et al.'' |title=Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP. |journal=Neuron |volume=21 |issue= 3 |pages= 581-91 |year= 1998 |pmid= 9768844 |doi= }}
*{{cite journal |vauthors=Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL, Bredt DS, Gale NW, Yancopoulos GD | title = PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands | journal = Neuron | volume = 21 | issue = 6 | pages = 1453–63 | year = 1999 | pmid = 9883737 | doi = 10.1016/S0896-6273(00)80663-7 }}
*{{cite journal | author=Torres R, Firestein BL, Dong H, ''et al.'' |title=PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. |journal=Neuron |volume=21 |issue= 6 |pages= 1453-63 |year= 1999 |pmid= 9883737 |doi= }}
*{{cite journal |vauthors=Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R | title = EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains | journal = Neuron | volume = 22 | issue = 3 | pages = 511–24 | year = 1999 | pmid = 10197531 | doi = 10.1016/S0896-6273(00)80706-0 }}
*{{cite journal | author=Brückner K, Pablo Labrador J, Scheiffele P, ''et al.'' |title=EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. |journal=Neuron |volume=22 |issue= 3 |pages= 511-24 |year= 1999 |pmid= 10197531 |doi= }}
*{{cite journal |vauthors=Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res. | volume = 6 | issue = 5 | pages = 337–45 | year = 2000 | pmid = 10574462 | doi = 10.1093/dnares/6.5.337 }}
*{{cite journal | author=Nagase T, Ishikawa K, Kikuno R, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 5 |pages= 337-45 |year= 2000 |pmid= 10574462 |doi= }}
*{{cite journal |vauthors=Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL | title = GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex | journal = Neuron | volume = 26 | issue = 3 | pages = 603–17 | year = 2000 | pmid = 10896157 | doi = 10.1016/S0896-6273(00)81198-8 }}
*{{cite journal | author=Ye B, Liao D, Zhang X, ''et al.'' |title=GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. |journal=Neuron |volume=26 |issue= 3 |pages= 603-17 |year= 2000 |pmid= 10896157 |doi= }}
*{{cite journal |vauthors=Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res. | volume = 7 | issue = 6 | pages = 347–55 | year = 2001 | pmid = 11214970 | doi = 10.1093/dnares/7.6.347 }}
*{{cite journal | author=Nagase T, Kikuno R, Hattori A, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 6 |pages= 347-55 |year= 2001 |pmid= 11214970 |doi= }}
*{{cite journal |vauthors=Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O | title = Characterization of long cDNA clones from human adult spleen | journal = DNA Res. | volume = 7 | issue = 6 | pages = 357–66 | year = 2001 | pmid = 11214971 | doi = 10.1093/dnares/7.6.357 }}
*{{cite journal | author=Hattori A, Okumura K, Nagase T, ''et al.'' |title=Characterization of long cDNA clones from human adult spleen. |journal=DNA Res. |volume=7 |issue= 6 |pages= 357-66 |year= 2001 |pmid= 11214971 |doi= }}
*{{cite journal |vauthors=Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O | title = The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering | journal = Mol. Pharmacol. | volume = 60 | issue = 5 | pages = 916–23 | year = 2001 | pmid = 11641419 | doi =  }}
*{{cite journal | author=Lin SH, Arai AC, Wang Z, ''et al.'' |title=The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. |journal=Mol. Pharmacol. |volume=60 |issue= 5 |pages= 916-23 |year= 2001 |pmid= 11641419 |doi=  }}
*{{cite journal |vauthors=Stegmüller J, Werner H, Nave KA, Trotter J | title = The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling | journal = J. Biol. Chem. | volume = 278 | issue = 6 | pages = 3590–8 | year = 2003 | pmid = 12458226 | doi = 10.1074/jbc.M210010200 }}
*{{cite journal | author=Stegmüller J, Werner H, Nave KA, Trotter J |title=The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling. |journal=J. Biol. Chem. |volume=278 |issue= 6 |pages= 3590-8 |year= 2003 |pmid= 12458226 |doi= 10.1074/jbc.M210010200 }}
*{{cite journal |vauthors=Ko J, Na M, Kim S, Lee JR, Kim E | title = Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins | journal = J. Biol. Chem. | volume = 278 | issue = 43 | pages = 42377–85 | year = 2004 | pmid = 12923177 | doi = 10.1074/jbc.M307561200 }}
*{{cite journal | author=Ko J, Na M, Kim S, ''et al.'' |title=Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. |journal=J. Biol. Chem. |volume=278 |issue= 43 |pages= 42377-85 |year= 2004 |pmid= 12923177 |doi= 10.1074/jbc.M307561200 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{PDB Gallery|geneid=80852}}
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{{gene-3-stub}}

Latest revision as of 09:06, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Glutamate receptor-interacting protein 2 is a protein that in humans is encoded by the GRIP2 gene.[1]

Interactions

GRIP2 has been shown to interact with liprin-alpha-1.[2][3]

References

  1. ↑ "Entrez Gene: GRIP2 glutamate receptor interacting protein 2".
  2. ↑ Ko J, Na M, Kim S, Lee JR, Kim E (Oct 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.
  3. ↑ Ko J, Kim S, Valtschanoff JG, Shin H, Lee JR, Sheng M, Premont RT, Weinberg RJ, Kim E (Mar 2003). "Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting". J. Neurosci. 23 (5): 1667–77. PMID 12629171.

Further reading

| citation =

  • Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
  • Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  • Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  • Srivastava S, Osten P, Vilim FS, Khatri L, Inman G, States B, Daly C, DeSouza S, Abagyan R, Valtschanoff JG, Weinberg RJ, Ziff EB (1998). "Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP". Neuron. 21 (3): 581–91. doi:10.1016/S0896-6273(00)80568-1. PMID 9768844.
  • Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL, Bredt DS, Gale NW, Yancopoulos GD (1999). "PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands". Neuron. 21 (6): 1453–63. doi:10.1016/S0896-6273(00)80663-7. PMID 9883737.
  • Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (1999). "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains". Neuron. 22 (3): 511–24. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531.
  • Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
  • Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.
  • Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
  • Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (2001). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi:10.1093/dnares/7.6.357. PMID 11214971.
  • Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O (2001). "The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering". Mol. Pharmacol. 60 (5): 916–23. PMID 11641419.
  • Stegmüller J, Werner H, Nave KA, Trotter J (2003). "The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling". J. Biol. Chem. 278 (6): 3590–8. doi:10.1074/jbc.M210010200. PMID 12458226.
  • Ko J, Na M, Kim S, Lee JR, Kim E (2004). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.


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