GRIPAP1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''GRIP1-associated protein 1''' is a [[protein]] that in humans is encoded by the ''GRIPAP1'' [[gene]].<ref name="pmid10896157">{{cite journal | vauthors = Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL | title = GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex | journal = Neuron | volume = 26 | issue = 3 | pages = 603–17  | date = Aug 2000 | pmid = 10896157 | pmc =  | doi = 10.1016/S0896-6273(00)81198-8 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GRIPAP1 GRIP1 associated protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56850| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = GRIP1 associated protein 1
| HGNCid = 18706
| Symbol = GRIPAP1
| AltSymbols =; DKFZp434P0630; GRASP-1; KIAA1167; MGC126593; MGC126595
| OMIM = 300408
| ECnumber = 
| Homologene = 41348
| MGIid = 1859616
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}}
| Process = {{GNF_GO|id=GO:0008150 |text = biological_process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 56850
    | Hs_Ensembl = ENSG00000068400
    | Hs_RefseqProtein = NP_064522
    | Hs_RefseqmRNA = NM_020137
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 48715078
    | Hs_GenLoc_end = 48743619
    | Hs_Uniprot = Q4V328
    | Mm_EntrezGene = 54645
    | Mm_Ensembl = ENSMUSG00000031153
    | Mm_RefseqmRNA = NM_207670
    | Mm_RefseqProtein = NP_997553
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 6946954
    | Mm_GenLoc_end = 6977522
    | Mm_Uniprot = Q8VD04
  }}
}}
'''GRIP1 associated protein 1''', also known as '''GRIPAP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GRIPAP1 GRIP1 associated protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56850| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated with the GRIP/AMPA receptor complex in brain (Ye et al., 2000).[supplied by OMIM]<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated with the GRIP/AMPA receptor complex in brain (Ye et al., 2000).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: GRIPAP1 GRIP1 associated protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56850| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
GRIPAP1 has been shown to [[Protein-protein interaction|interact]] with [[GRIP1 (gene)|GRIP1]].<ref name=pmid10896157 />
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O | title = Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain | journal = DNA Res. | volume = 6 | issue = 5 | pages = 329–36 | year = 1999 | pmid = 10574461 | doi = 10.1093/dnares/6.5.329 }}
| citations =
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Res. | volume = 11 | issue = 3 | pages = 422–35 | year = 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
*{{cite journal | author=Hirosawa M, Nagase T, Ishikawa K, ''et al.'' |title=Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. |journal=DNA Res. |volume=6 |issue= 5 |pages= 329-36 |year= 2000 |pmid= 10574461 |doi= }}
* {{cite journal | vauthors = Kino T, Slobodskaya O, Pavlakis GN, Chrousos GP | title = Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex | journal = J. Biol. Chem. | volume = 277 | issue = 4 | pages = 2396–405 | year = 2002 | pmid = 11704662 | doi = 10.1074/jbc.M106312200 }}
*{{cite journal  | author=Ye B, Liao D, Zhang X, ''et al.'' |title=GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. |journal=Neuron |volume=26 |issue= 3 |pages= 603-17 |year= 2000 |pmid= 10896157 |doi=  }}
* {{cite journal | vauthors = Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK | title = The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs | journal = J. Biol. Chem. | volume = 277 | issue = 18 | pages = 15221–4 | year = 2002 | pmid = 11891216 | doi = 10.1074/jbc.C200112200 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
* {{cite journal | vauthors = Ye B, Sugo N, Hurn PD, Huganir RL | title = Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody | journal = Neuroscience | volume = 114 | issue = 1 | pages = 217–27 | year = 2002 | pmid = 12207967 | doi = 10.1016/S0306-4522(02)00142-2 }}
*{{cite journal | author=Kino T, Slobodskaya O, Pavlakis GN, Chrousos GP |title=Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex. |journal=J. Biol. Chem. |volume=277 |issue= 4 |pages= 2396-405 |year= 2002 |pmid= 11704662 |doi= 10.1074/jbc.M106312200 }}
* {{cite journal | vauthors = Coutts AS, MacKenzie E, Griffith E, Black DM | title = TES is a novel focal adhesion protein with a role in cell spreading | journal = J. Cell Sci. | volume = 116 | issue = Pt 5 | pages = 897–906 | year = 2003 | pmid = 12571287 | doi = 10.1242/jcs.00278 }}
*{{cite journal | author=Hirbec H, Perestenko O, Nishimune A, ''et al.'' |title=The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. |journal=J. Biol. Chem. |volume=277 |issue= 18 |pages= 15221-4 |year= 2002 |pmid= 11891216 |doi= 10.1074/jbc.C200112200 }}
* {{cite journal | vauthors = Nakata A, Ito T, Nagata M, Hori S, Sekimizu K | title = GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1 | journal = Genes Cells | volume = 9 | issue = 11 | pages = 1125–35 | year = 2004 | pmid = 15507123 | doi = 10.1111/j.1365-2443.2004.00795.x }}
*{{cite journal | author=Ye B, Sugo N, Hurn PD, Huganir RL |title=Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody. |journal=Neuroscience |volume=114 |issue= 1 |pages= 217-27 |year= 2002 |pmid= 12207967 |doi= }}
* {{cite journal | vauthors = Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL | title = High-throughput mapping of a dynamic signaling network in mammalian cells | journal = Science | volume = 307 | issue = 5715 | pages = 1621–5 | year = 2005 | pmid = 15761153 | doi = 10.1126/science.1105776 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Stinton LM, Selak S, Fritzler MJ | title = Identification of GRASP-1 as a novel 97 kDa autoantigen localized to endosomes | journal = Clin. Immunol. | volume = 116 | issue = 2 | pages = 108–17 | year = 2005 | pmid = 15897011 | doi = 10.1016/j.clim.2005.03.021 }}
*{{cite journal | author=Coutts AS, MacKenzie E, Griffith E, Black DM |title=TES is a novel focal adhesion protein with a role in cell spreading. |journal=J. Cell. Sci. |volume=116 |issue= Pt 5 |pages= 897-906 |year= 2003 |pmid= 12571287 |doi=  }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Nakata A, Ito T, Nagata M, ''et al.'' |title=GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1. |journal=Genes Cells |volume=9 |issue= 11 |pages= 1125-35 |year= 2005 |pmid= 15507123 |doi= 10.1111/j.1365-2443.2004.00795.x }}
*{{cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, ''et al.'' |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621-5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
*{{cite journal | author=Ross MT, Grafham DV, Coffey AJ, ''et al.'' |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325-37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 }}
*{{cite journal  | author=Stinton LM, Selak S, Fritzler MJ |title=Identification of GRASP-1 as a novel 97 kDa autoantigen localized to endosomes. |journal=Clin. Immunol. |volume=116 |issue= 2 |pages= 108-17 |year= 2005 |pmid= 15897011 |doi= 10.1016/j.clim.2005.03.021 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
 
{{WikiDoc Sources}}
{{gene-X-stub}}

Latest revision as of 20:01, 8 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

GRIP1-associated protein 1 is a protein that in humans is encoded by the GRIPAP1 gene.[1][2]

Function

GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated with the GRIP/AMPA receptor complex in brain (Ye et al., 2000).[supplied by OMIM][2]

Interactions

GRIPAP1 has been shown to interact with GRIP1.[1]

References

  1. ↑ 1.0 1.1 Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (Aug 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.
  2. ↑ 2.0 2.1 "Entrez Gene: GRIPAP1 GRIP1 associated protein 1".

Further reading

  • Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (1999). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Kino T, Slobodskaya O, Pavlakis GN, Chrousos GP (2002). "Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex". J. Biol. Chem. 277 (4): 2396–405. doi:10.1074/jbc.M106312200. PMID 11704662.
  • Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK (2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. 277 (18): 15221–4. doi:10.1074/jbc.C200112200. PMID 11891216.
  • Ye B, Sugo N, Hurn PD, Huganir RL (2002). "Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody". Neuroscience. 114 (1): 217–27. doi:10.1016/S0306-4522(02)00142-2. PMID 12207967.
  • Coutts AS, MacKenzie E, Griffith E, Black DM (2003). "TES is a novel focal adhesion protein with a role in cell spreading". J. Cell Sci. 116 (Pt 5): 897–906. doi:10.1242/jcs.00278. PMID 12571287.
  • Nakata A, Ito T, Nagata M, Hori S, Sekimizu K (2004). "GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1". Genes Cells. 9 (11): 1125–35. doi:10.1111/j.1365-2443.2004.00795.x. PMID 15507123.
  • Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
  • Stinton LM, Selak S, Fritzler MJ (2005). "Identification of GRASP-1 as a novel 97 kDa autoantigen localized to endosomes". Clin. Immunol. 116 (2): 108–17. doi:10.1016/j.clim.2005.03.021. PMID 15897011.


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