KIFAP3: Difference between revisions

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Latest revision as of 06:28, 2 September 2017

Kinesin-associated protein 3 is a protein that in humans is encoded by the KIFAP3 (also known as KAP3) gene.^[1]^[2] It is a non-motor, accessory subunit which co-oligomerizes with the motor subunits KIF3A and KIF3B or KIF3C, to form heterotrimeric kinesin-2 motor proteins. Kinesin-2 KAP subunits were initially characterized in echinoderms and mice.^[3]^[4]

Function

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 Armadillo repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src , and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.^[2]

Interactions

KIFAP3 has been shown to interact with APC ,^[5] SMC3 ^[6] and RAP1GDS1 .^[1]

References

↑ ^1.0 ^1.1 Shimizu K, Kawabe H, Minami S, Honda T, Takaishi K, Shirataki H, Takai Y (Dec 1996). "SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase". J Biol Chem. 271 (43): 27013–7. doi:10.1074/jbc.271.43.27013. PMID 8900189.
↑ ^2.0 ^2.1 "Entrez Gene: KIFAP3 kinesin-associated protein 3".
↑ Wedaman KP, Meyer DW, Rashid DJ, Cole DG, Scholey JM (February 1996). "Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex". J. Cell Biol. 132 (3): 371–80. doi:10.1083/jcb.132.3.371. PMC 2120715. PMID 8636215.
↑ Yamazaki H, Nakata T, Okada Y, Hirokawa N (August 1996). "Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B". Proc. Natl. Acad. Sci. U.S.A. 93 (16): 8443–8. doi:10.1073/pnas.93.16.8443. PMC 38690. PMID 8710890.
↑ Jimbo T, Kawasaki Y, Koyama R, Sato R, Takada S, Haraguchi K, Akiyama T (April 2002). "Identification of a link between the tumour suppressor APC and the kinesin superfamily". Nat. Cell Biol. 4 (4): 323–7. doi:10.1038/ncb779. PMID 11912492.
↑ Shimizu K, Shirataki H, Honda T, Minami S, Takai Y (March 1998). "Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide". J. Biol. Chem. 273 (12): 6591–4. doi:10.1074/jbc.273.12.6591. PMID 9506951.

Nagata K, Puls A, Futter C, et al. (1998). "The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3". EMBO J. 17 (1): 149–58. doi:10.1093/emboj/17.1.149. PMC 1170366. PMID 9427749.
Shimizu K, Shirataki H, Honda T, et al. (1998). "Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide". J. Biol. Chem. 273 (12): 6591–4. doi:10.1074/jbc.273.12.6591. PMID 9506951.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Khanna H, Hurd TW, Lillo C, et al. (2005). "RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins". J. Biol. Chem. 280 (39): 33580–7. doi:10.1074/jbc.M505827200. PMC 1249479. PMID 16043481.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Brown CL, Maier KC, Stauber T, et al. (2006). "Kinesin-2 is a motor for late endosomes and lysosomes". Traffic. 6 (12): 1114–24. doi:10.1111/j.1600-0854.2005.00347.x. PMID 16262723.
Haraguchi K, Hayashi T, Jimbo T, et al. (2006). "Role of the kinesin-2 family protein, KIF3, during mitosis". J. Biol. Chem. 281 (7): 4094–9. doi:10.1074/jbc.M507028200. PMID 16298999.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Kuraguchi M, Wang XP, Bronson RT, et al. (2006). "Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus". PLoS Genet. 2 (9): e146. doi:10.1371/journal.pgen.0020146. PMC 1564426. PMID 17002498.
Stauber T, Simpson JC, Pepperkok R, Vernos I (2007). "A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex". Curr. Biol. 16 (22): 2245–51. doi:10.1016/j.cub.2006.09.060. PMID 17113389.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid8900189-1] 1.0 ^1.1 Shimizu K, Kawabe H, Minami S, Honda T, Takaishi K, Shirataki H, Takai Y (Dec 1996). "SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase". J Biol Chem. 271 (43): 27013–7. doi:10.1074/jbc.271.43.27013. PMID 8900189.

[entrez-2] 2.0 ^2.1 "Entrez Gene: KIFAP3 kinesin-associated protein 3".

[pmid8636215-3] Wedaman KP, Meyer DW, Rashid DJ, Cole DG, Scholey JM (February 1996). "Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex". J. Cell Biol. 132 (3): 371–80. doi:10.1083/jcb.132.3.371. PMC 2120715. PMID 8636215.

[pmid8710890-4] Yamazaki H, Nakata T, Okada Y, Hirokawa N (August 1996). "Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B". Proc. Natl. Acad. Sci. U.S.A. 93 (16): 8443–8. doi:10.1073/pnas.93.16.8443. PMC 38690. PMID 8710890.

[pmid11912492-5] Jimbo T, Kawasaki Y, Koyama R, Sato R, Takada S, Haraguchi K, Akiyama T (April 2002). "Identification of a link between the tumour suppressor APC and the kinesin superfamily". Nat. Cell Biol. 4 (4): 323–7. doi:10.1038/ncb779. PMID 11912492.

[pmid9506951-6] Shimizu K, Shirataki H, Honda T, Minami S, Takai Y (March 1998). "Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide". J. Biol. Chem. 273 (12): 6591–4. doi:10.1074/jbc.273.12.6591. PMID 9506951.

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-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Kinesin-associated protein 3''' is a [[protein]] that in humans is encoded by the ''KIFAP3'' (also known as ''KAP3'') [[gene]].<ref name="pmid8900189">{{cite journal |vauthors=Shimizu K, Kawabe H, Minami S, Honda T, Takaishi K, Shirataki H, Takai Y | title = SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase | journal = J Biol Chem | volume = 271 | issue = 43 | pages = 27013–7 |date=Dec 1996 | pmid = 8900189 | pmc =  | doi =10.1074/jbc.271.43.27013  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KIFAP3 kinesin-associated protein 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22920| accessdate = }}</ref> It is a non-motor, accessory subunit which co-oligomerizes with the motor subunits KIF3A and KIF3B or KIF3C, to form heterotrimeric kinesin-2 motor proteins. Kinesin-2 KAP subunits were initially characterized in echinoderms and mice.<ref name="pmid8636215">{{cite journal |vauthors=Wedaman KP, Meyer DW, Rashid DJ, Cole DG, Scholey JM | title = Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex | journal = J. Cell Biol. | volume = 132 | issue = 3 | pages = 371–80 |date=February 1996 | pmid = 8636215 | pmc = 2120715 | doi = 10.1083/jcb.132.3.371}}</ref><ref name="pmid8710890">{{cite journal |vauthors=Yamazaki H, Nakata T, Okada Y, Hirokawa N | title = Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 93 | issue = 16 | pages = 8443–8 |date=August 1996 | pmid = 8710890 | pmc = 38690 | doi = 10.1073/pnas.93.16.8443}}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Function ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Kinesin-associated protein 3
- | HGNCid = 17060
- | Symbol = KIFAP3
- | AltSymbols =; SMAP; FLJ22818; KAP3; Smg-GDS; dJ190I16.1
- | OMIM = 601836
- | ECnumber =
- | Homologene = 7799
- | MGIid = 107566
- | GeneAtlas_image1 = PBB_GE_KIFAP3_203333_at_tn.png
- | Function = {{GNF_GO|id=GO:0005488 |text = binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0019894 |text = kinesin binding}}
- | Component = {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005871 |text = kinesin complex}} {{GNF_GO|id=GO:0016939 |text = kinesin II complex}}
- | Process = {{GNF_GO|id=GO:0006461 |text = protein complex assembly}} {{GNF_GO|id=GO:0007017 |text = microtubule-based process}} {{GNF_GO|id=GO:0007165 |text = signal transduction}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 22920
-    | Hs_Ensembl = ENSG00000075945
-    | Hs_RefseqProtein = NP_055785
-    | Hs_RefseqmRNA = NM_014970
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 1
-    | Hs_GenLoc_start = 168157091
-    | Hs_GenLoc_end = 168310503
-    | Hs_Uniprot = Q92845
-    | Mm_EntrezGene = 16579
-    | Mm_Ensembl = ENSMUSG00000026585
-    | Mm_RefseqmRNA = NM_010629
-    | Mm_RefseqProtein = NP_034759
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 1
-    | Mm_GenLoc_start = 165616268
-    | Mm_GenLoc_end = 165753775
-    | Mm_Uniprot = Q3UZA5
-  }}
-}}
-'''Kinesin-associated protein 3''', also known as '''KIFAP3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: KIFAP3 kinesin-associated protein 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22920| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+The small G protein GDP dissociation stimulator ([[RAP1GDS1|smg GDS]]) is a regulator protein having two activities on a group of [[small GTPase|small G protein]]s including the [[Rho family of GTPases|Rho]] and [[Rap1]] family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9  [[Armadillo repeats]] and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the [[endoplasmic reticulum]], is [[phosphorylation|phosphorylated]] by {{SWL|target= Src (gene)|label=v-src|type=phosphorylated_by}}, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide ([[SMC2|HCAP]]) and KIF3A/B, a [[kinesin]] superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.<ref name="entrez" />
-{{PBB_Summary
-| section_title =
-| summary_text = The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.<ref name="entrez">{{cite web | title = Entrez Gene: KIFAP3 kinesin-associated protein 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22920| accessdate = }}</ref>
-}}
-==References==
+== Interactions ==
-{{reflist|2}}
-==Further reading==
+KIFAP3 has been shown to [[Protein-protein interaction|interact]] with {{SWL|target=APC (gene)|label=APC|type=PPI}},<ref name="pmid11912492">{{cite journal |vauthors=Jimbo T, Kawasaki Y, Koyama R, Sato R, Takada S, Haraguchi K, Akiyama T | title = Identification of a link between the tumour suppressor APC and the kinesin superfamily | journal = Nat. Cell Biol. | volume = 4 | issue = 4 | pages = 323–7 |date=April 2002 | pmid = 11912492 | doi = 10.1038/ncb779 | url =  }}</ref> {{SWL|target=SMC3 (gene)|type=PPI|label=SMC3}}<ref name="pmid9506951">{{cite journal |vauthors=Shimizu K, Shirataki H, Honda T, Minami S, Takai Y | title = Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide | journal = J. Biol. Chem. | volume = 273 | issue = 12 | pages = 6591–4 |date=March 1998 | pmid = 9506951 | doi = 10.1074/jbc.273.12.6591| url =  }}</ref> and {{SWL|target=RAP1GDS1|type=PPI}}.<ref name="pmid8900189" />
+== References ==
+{{reflist}}
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+*{{cite journal  | author=Nagata K |title=The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3 |journal=EMBO J. |volume=17 |issue= 1 |pages= 149–58 |year= 1998 |pmid= 9427749 |doi= 10.1093/emboj/17.1.149  | pmc=1170366  |name-list-format=vanc| author2=Puls A  | author3=Futter C  | display-authors=3  | last4=Aspenstrom  | first4=P  | last5=Schaefer  | first5=E  | last6=Nakata  | first6=T  | last7=Hirokawa  | first7=N  | last8=Hall  | first8=A }}
-| citations =
+*{{cite journal  | author=Shimizu K |title=Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide |journal=J. Biol. Chem. |volume=273 |issue= 12 |pages= 6591–4 |year= 1998 |pmid= 9506951 |doi=10.1074/jbc.273.12.6591  |name-list-format=vanc| author2=Shirataki H  | author3=Honda T  | display-authors=3  | last4=Minami  | first4=S  | last5=Takai  | first5=Y  }}
-*{{cite journal  | author=Shimizu K, Kawabe H, Minami S, ''et al.'' |title=SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase. |journal=J. Biol. Chem. |volume=271 |issue= 43 |pages= 27013-7 |year= 1996 |pmid= 8900189 |doi=  }}
+*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
-*{{cite journal  | author=Nagata K, Puls A, Futter C, ''et al.'' |title=The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3. |journal=EMBO J. |volume=17 |issue= 1 |pages= 149-58 |year= 1998 |pmid= 9427749 |doi= 10.1093/emboj/17.1.149 }}
+*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
-*{{cite journal  | author=Shimizu K, Shirataki H, Honda T, ''et al.'' |title=Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide. |journal=J. Biol. Chem. |volume=273 |issue= 12 |pages= 6591-4 |year= 1998 |pmid= 9506951 |doi=  }}
+*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
-*{{cite journal  | author=Jimbo T, Kawasaki Y, Koyama R, ''et al.'' |title=Identification of a link between the tumour suppressor APC and the kinesin superfamily. |journal=Nat. Cell Biol. |volume=4 |issue= 4 |pages= 323-7 |year= 2002 |pmid= 11912492 |doi= 10.1038/ncb779 }}
+*{{cite journal  | author=Khanna H |title=RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins |journal=J. Biol. Chem. |volume=280 |issue= 39 |pages= 33580–7 |year= 2005 |pmid= 16043481 |doi= 10.1074/jbc.M505827200  | pmc=1249479  |name-list-format=vanc| author2=Hurd TW  | author3=Lillo C  | display-authors=3  | last4=Shu  | first4=X  | last5=Parapuram  | first5=SK  | last6=He  | first6=S  | last7=Akimoto  | first7=M  | last8=Wright  | first8=AF  | last9=Margolis  | first9=B }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209  |name-list-format=vanc| author2=Venkatesan K  | author3=Hao T  | display-authors=3  | last4=Hirozane-Kishikawa  | first4=Tomoko  | last5=Dricot  | first5=Amélie  | last6=Li  | first6=Ning  | last7=Berriz  | first7=Gabriel F.  | last8=Gibbons  | first8=Francis D.  | last9=Dreze  | first9=Matija }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | author=Brown CL |title=Kinesin-2 is a motor for late endosomes and lysosomes |journal=Traffic |volume=6 |issue= 12 |pages= 1114–24 |year= 2006 |pmid= 16262723 |doi= 10.1111/j.1600-0854.2005.00347.x  |name-list-format=vanc| author2=Maier KC  | author3=Stauber T  | display-authors=3  | last4=Ginkel  | first4=Laura M.  | last5=Wordeman  | first5=Linda  | last6=Vernos  | first6=Isabelle  | last7=Schroer  | first7=Trina A. }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | author=Haraguchi K |title=Role of the kinesin-2 family protein, KIF3, during mitosis |journal=J. Biol. Chem. |volume=281 |issue= 7 |pages= 4094–9 |year= 2006 |pmid= 16298999 |doi= 10.1074/jbc.M507028200  |name-list-format=vanc| author2=Hayashi T  | author3=Jimbo T  | display-authors=3  | last4=Yamamoto  | first4=T  | last5=Akiyama  | first5=T }}
-*{{cite journal  | author=Khanna H, Hurd TW, Lillo C, ''et al.'' |title=RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. |journal=J. Biol. Chem. |volume=280 |issue= 39 |pages= 33580-7 |year= 2005 |pmid= 16043481 |doi= 10.1074/jbc.M505827200 }}
+*{{cite journal  | author=Gregory SG |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727  |name-list-format=vanc| author2=Barlow KF  | author3=McLay KE  | display-authors=3  | last4=Kaul  | first4=R.  | last5=Swarbreck  | first5=D.  | last6=Dunham  | first6=A.  | last7=Scott  | first7=C. E.  | last8=Howe  | first8=K. L.  | last9=Woodfine  | first9=K. }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
+*{{cite journal  | author=Lim J |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032  |name-list-format=vanc| author2=Hao T  | author3=Shaw C  | display-authors=3  | last4=Patel  | first4=Akash J.  | last5=Szabó  | first5=Gábor  | last6=Rual  | first6=Jean-François  | last7=Fisk  | first7=C. Joseph  | last8=Li  | first8=Ning  | last9=Smolyar  | first9=Alex }}
-*{{cite journal  | author=Brown CL, Maier KC, Stauber T, ''et al.'' |title=Kinesin-2 is a motor for late endosomes and lysosomes. |journal=Traffic |volume=6 |issue= 12 |pages= 1114-24 |year= 2006 |pmid= 16262723 |doi= 10.1111/j.1600-0854.2005.00347.x }}
+*{{cite journal  | author=Kuraguchi M |title=Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus |journal=PLoS Genet. |volume=2 |issue= 9 |pages= e146 |year= 2006 |pmid= 17002498 |doi= 10.1371/journal.pgen.0020146  | pmc=1564426  |name-list-format=vanc| author2=Wang XP  | author3=Bronson RT  | display-authors=3  | last4=Rothenberg  | first4=Rebecca  | last5=Ohene-Baah  | first5=Nana Yaw  | last6=Lund  | first6=Jennifer J.  | last7=Kucherlapati  | first7=Melanie  | last8=Maas  | first8=Richard L.  | last9=Kucherlapati  | first9=Raju }}
-*{{cite journal  | author=Haraguchi K, Hayashi T, Jimbo T, ''et al.'' |title=Role of the kinesin-2 family protein, KIF3, during mitosis. |journal=J. Biol. Chem. |volume=281 |issue= 7 |pages= 4094-9 |year= 2006 |pmid= 16298999 |doi= 10.1074/jbc.M507028200 }}
+*{{cite journal  |vauthors=Stauber T, Simpson JC, Pepperkok R, Vernos I |title=A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex |journal=Curr. Biol. |volume=16 |issue= 22 |pages= 2245–51 |year= 2007 |pmid= 17113389 |doi= 10.1016/j.cub.2006.09.060 }}
-*{{cite journal  | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
-*{{cite journal  | author=Lim J, Hao T, Shaw C, ''et al.'' |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801-14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
-*{{cite journal  | author=Kuraguchi M, Wang XP, Bronson RT, ''et al.'' |title=Adenomatous polyposis coli (APC) is required for normal development of skin and thymus. |journal=PLoS Genet. |volume=2 |issue= 9 |pages= e146 |year= 2006 |pmid= 17002498 |doi= 10.1371/journal.pgen.0020146 }}
-*{{cite journal  | author=Stauber T, Simpson JC, Pepperkok R, Vernos I |title=A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex. |journal=Curr. Biol. |volume=16 |issue= 22 |pages= 2245-51 |year= 2007 |pmid= 17113389 |doi= 10.1016/j.cub.2006.09.060 }}
-}}
 {{refend}}
-{{protein-stub}}
-{{WikiDoc Sources}}
+{{gene-1-stub}}
+[[Category:Armadillo-repeat-containing proteins]]

KIFAP3: Difference between revisions

Latest revision as of 06:28, 2 September 2017

Contents

Function

Interactions

References

Further reading

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