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'''Lanolin''', also called '''Adeps Lanae''', '''wool wax''', '''wool fat''', or '''wool grease''', a greasy yellow substance from wool-bearing animals, acts as a skin ointment, water-proofing wax, and raw material (such as in [[shoe polish]]).  Lanolin is "wool [[fat]]" or grease, chemically akin to [[wax]], which is secreted by the [[sebaceous gland]]s of [[wool]]-bearing animals, such as [[sheep]]. These glands are associated with [[hair follicle]]s.  Lanolin's ability to act as a waterproofing wax aids sheep in shedding [[water]] from their coats.  Certain breeds of sheep produce large amounts of lanolin, and the extraction can be performed by squeezing the wool between rollers. Most or all the lanolin is removed from wool when it is processed into [[textiles]], eg [[yarn]] or [[felt]].  The Fanning Corporation is the only lanolin producer with a refinery located in the United States.
{{DrugProjectFormSinglePage
|authorTag={{KS}}
|OTC=Yes
|genericName=lanolin
|aOrAn=a
|drugClass=non-petroleum based lubricants
|indicationType=treatment
|indication=diaper [[dermatitis]] and protection of chafed skin or minor skin irritations due to incontinence
|adverseReactions=burning, stinging, redness and  irritation
|blackBoxWarningTitle=<span style="color:#FF0000;">ConditionName: </span>
|blackBoxWarningBody=<i><span style="color:#FF0000;">ConditionName: </span></i>


Lanolin is chiefly a mixture of [[cholesterol]] and the [[ester]]s of several [[fatty acid]]s. Crude (non-medical) grades of lanolin also contain [[wool alcohol]]s, which are an [[allergen]] for some people. Recent studies also indicate that [[antibiotic]]s are present in the lanolin.  The extract is insoluble in water, but forms an [[emulsion]]. At one point, the name Lanolin was trademarked as the generic term for a preparation of sheep fat and water.
* Content
<ref name="tradecourt">{{cite court 
|litigants=Jaffe v. Evans & Sons, Ltd.
|vol=
|reporter=U.S.
|opinion=
|pinpoint=
|court=Supreme Court, Appellate Division, First Department, New York
|date=March 21, 1902
|url=}}</ref>


Lanolin is used commercially in a great many products ranging from [[rust]]-preventative coatings to [[cosmetics]] to [[lubricant]]s. Some sailors use lanolin to create a slippery surface on their propellers and stern gear to which [[barnacles]] cannot adhere. The water-repellent properties make it valuable as a lubricant grease where corrosion would otherwise be a problem, particularly on stainless steel, which becomes more vulnerable to corrosion when starved of oxygen.
<!--Adult Indications and Dosage-->


'''Medical grade lanolin''' is used as a cream to soothe [[skin]]. It is pure, [[hypoallergenic]] and [[bacteriostatic]]. In this form it is used by some [[breastfeeding]] mothers on sore and cracked nipples. This grade of lanolin can also be used to treat [[chapped lips]], [[diaper rash]], dry skin, itchy skin, rough feet, minor cuts, minor [[burn (injury)|burns]] and skin abrasions.  As an [[ointment]] base, it is readily absorbed through [[skin]], facilitating absorption of the medicinal chemicals it carries.
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult=There is limited information regarding <i>FDA-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
|offLabelAdultGuideSupport=There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
|offLabelAdultNoGuideSupport=* There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in adult patients.
|fdaLIADPed===Indications==
* Helps prevent and treat diaper [[dermatitis]]


The name given to the product '[[Olay|Oil of Olay]]' is derived from the word "lanolin," a key ingredient, which was chosen by the inventor, Graham Wulff.<ref name="olay-wulff">{{cite web | url = http://www.uk.pg.com/products/products/olay.html  | title = History of Olay | publisher = Procter & Gamble}}</ref>
* Protects chafed skin or minor skin irritations due to incontinence and helps seal out wetness.
|offLabelPedGuideSupport=* There is limited information regarding <i>Off-Label Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
|offLabelPedNoGuideSupport=* There is limited information regarding <i>Off-Label Non–Guideline-Supported Use</i> of {{PAGENAME}} in pediatric patients.
|warnings=* For External Use Only
* Avoid contact with eyes
* Do not apply to deep or puncture wounds
* If condition worsens, or does not improve within 7 days, consult a doctor


Using cosmetic products which contain too much lanolin can result in an allergic reaction in some people.
'''KEEP OUT OF REACH OF CHILDREN'''


Lanolin is often used as a raw material for producing [[Cholecalciferol|vitamin D3]].
* If swallowed, get medical help or contact a Poison Control Center right away
|clinicalTrials=* There is limited information regarding <i>Clinical Trial Experience</i> of {{PAGENAME}} in the drug label.
|postmarketing=* There is limited information regarding <i>Postmarketing Experience</i> of {{PAGENAME}} in the drug label.
|useInPregnancyAUS=* There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of {{PAGENAME}} in women who are pregnant.
|useInLaborDelivery=There is no FDA guidance on use of {{PAGENAME}} during labor and delivery.
|useInNursing=There is no FDA guidance on the use of {{PAGENAME}} with respect to nursing mothers.
|useInPed=There is no FDA guidance on the use of {{PAGENAME}} with respect to pediatric patients.
|useInGeri=There is no FDA guidance on the use of {{PAGENAME}} with respect to geriatric patients.
|useInGender=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific gender populations.
|useInRace=There is no FDA guidance on the use of {{PAGENAME}} with respect to specific racial populations.
|useInRenalImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with renal impairment.
|useInHepaticImpair=There is no FDA guidance on the use of {{PAGENAME}} in patients with hepatic impairment.
|useInReproPotential=There is no FDA guidance on the use of {{PAGENAME}} in women of reproductive potentials and males.
|useInImmunocomp=There is no FDA guidance one the use of {{PAGENAME}} in patients who are immunocompromised.
|administration=* Topical
* Gently cleanse and dry area
* Apply liberally to affected area as needed
* Avoid contact with eyes
* Do not apply to deep or puncture wounds
* If condition worsens, or does not improve within 7 days, consult a doctor
|monitoring=* There is limited information regarding <i>Monitoring</i> of {{PAGENAME}} in the drug label.


==More Information on Lanolin==


Lanolin is a unique natural substance derived from the greasy coating on raw wool.  It is an all-natural, highly effective substance which acts as a moisture barrier and lubricant.  Its unique properties have been recognised for centuries, and have not, as yet, been possible for scientists to duplicate.
In Australia, the use of lanolin became less common from the late 1940s onwards, as the use of harsh toxic chemicals became the industry norm.
In the last few decades however, there has been a shift in people’s attitudes and the realisation that society cannot continue to degrade the environment through the use of petrochemical based products.  Consequently, there has been a move towards using more environmentally friendly alternatives.
Quick facts on lanolin:
*Lanolin is secreted from a sheep’s sebaceous glands and acts as a waterproofer to protect the sheep’s wool from the elements
*It is made up of a mixture of wax, fatty acids and alcohols
*Crude lanolin constitutes approximately 5-25% of the weight of freshly shorn wool
*The wool from one Merino sheep will produce about 250-300ml of recoverable wool grease (lanolin)
*Lanolin is extracted from wool via a scouring process. This process involves washing the wool in hot water with a special wool scouring detergent to remove dirt, wool grease (crude lanolin), suint (sweat salts), and anything else stuck to the wool. The wool grease is continuously removed during this washing process by centrifugal separators, which concentrate the wool grease into a wax-like substance melting at approximately 38ºC.
*To date, scientists have been unable to duplicate either the performance or composition of lanolin.


==References==
<!--IV Compatibility-->
{{reflist|2}}
|IVCompat=* There is limited information regarding <i>IV Compatibility</i> of {{PAGENAME}} in the drug label.
{{E number infobox 910-919}}
|overdose=* There is limited information regarding <i>Chronic Overdose</i> of {{PAGENAME}} in the drug label.


[[Category:Animal glandular products]]
[[Category:Waxes]]
[[Category:Lubricants]]


[[da:Lanolin]]
[[de:Wollwachs]]
[[es:Lanolina]]
[[eo:Lanolino]]
[[it:Lanolina]]
[[pl:Lanolina]]
[[pt:Lanolina]]
[[fi:Lanoliini]]
[[sv:Lanolin]]
[[ru:Ланолин]]


==Links==
<!--Drug box 2-->
|PD=There is limited information regarding <i>Pharmacodynamics</i> of {{PAGENAME}} in the drug label.
|PK=There is limited information regarding <i>Pharmacokinetics</i> of {{PAGENAME}} in the drug label.
|nonClinToxic=There is limited information regarding <i>Nonclinical Toxicology</i> of {{PAGENAME}} in the drug label.
|clinicalStudies=There is limited information regarding <i>Clinical Studies</i> of {{PAGENAME}} in the drug label.
|storage=* Store at room temperature 20 deg C to 25 deg C 68 deg F to 77 deg F
|packLabel=[[File:Lanolin image.jpg|thumb|none|600px|This image is provided by the National Library of Medicine.]]


[http://www.lanotec.com.au] '''Lanotec''' - Lanolin based alternatives to petro-chemical products
[[File:Lanolin ingredients and appearance.png|thumb|none|600px|This image is provided by the National Library of Medicine.]]
{{WikiDoc Help Menu}}
|fdaPatientInfo=There is limited information regarding <i>Patient Counseling Information</i> of {{PAGENAME}} in the drug label.
{{WikiDoc Sources}}
|alcohol=* Alcohol-{{PAGENAME}} interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
|brandNames=*  LANOLIN ®<ref>{{Cite web | title =lanolin ointment| url =http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=87216888-1753-4fd5-a8e0-d8347948b082 }}</ref>
|lookAlike=* A® — B®<ref name="www.ismp.org">{{Cite web  | last =  | first =  | title = http://www.ismp.org | url = http://www.ismp.org | publisher =  | date =  }}</ref>
|drugShortage=
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[[Category:Drug]]

Latest revision as of 16:34, 20 August 2015

Lanolin
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Lanolin is a non-petroleum based lubricants that is FDA approved for the treatment of diaper dermatitis and protection of chafed skin or minor skin irritations due to incontinence. Common adverse reactions include burning, stinging, redness and irritation.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

There is limited information regarding FDA-Label Guideline-Supported Use of Lanolin in adult patients.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Lanolin in adult patients.

Non–Guideline-Supported Use

  • There is limited information regarding Off-Label Non–Guideline-Supported Use of Lanolin in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Indications

  • Protects chafed skin or minor skin irritations due to incontinence and helps seal out wetness.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

  • There is limited information regarding Off-Label Guideline-Supported Use of Lanolin in pediatric patients.

Non–Guideline-Supported Use

  • There is limited information regarding Off-Label Non–Guideline-Supported Use of Lanolin in pediatric patients.

Contraindications

There is limited information regarding Lanolin Contraindications in the drug label.

Warnings

  • For External Use Only
  • Avoid contact with eyes
  • Do not apply to deep or puncture wounds
  • If condition worsens, or does not improve within 7 days, consult a doctor

KEEP OUT OF REACH OF CHILDREN

  • If swallowed, get medical help or contact a Poison Control Center right away

Adverse Reactions

Clinical Trials Experience

  • There is limited information regarding Clinical Trial Experience of Lanolin in the drug label.

Postmarketing Experience

  • There is limited information regarding Postmarketing Experience of Lanolin in the drug label.

Drug Interactions

There is limited information regarding Lanolin Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Lanolin in women who are pregnant.
Pregnancy Category (AUS):

  • There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Lanolin in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Lanolin during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Lanolin with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Lanolin with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Lanolin with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Lanolin with respect to specific gender populations.

Race

There is no FDA guidance on the use of Lanolin with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Lanolin in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Lanolin in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Lanolin in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Lanolin in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Topical
  • Gently cleanse and dry area
  • Apply liberally to affected area as needed
  • Avoid contact with eyes
  • Do not apply to deep or puncture wounds
  • If condition worsens, or does not improve within 7 days, consult a doctor

Monitoring

  • There is limited information regarding Monitoring of Lanolin in the drug label.

IV Compatibility

  • There is limited information regarding IV Compatibility of Lanolin in the drug label.

Overdosage

  • There is limited information regarding Chronic Overdose of Lanolin in the drug label.

Pharmacology

There is limited information regarding Lanolin Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Lanolin Mechanism of Action in the drug label.

Structure

There is limited information regarding Lanolin Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Lanolin in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Lanolin in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Lanolin in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Lanolin in the drug label.

How Supplied

There is limited information regarding Lanolin How Supplied in the drug label.

Storage

  • Store at room temperature 20 deg C to 25 deg C 68 deg F to 77 deg F

Images

Drug Images

{{#ask: Page Name::Lanolin |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

This image is provided by the National Library of Medicine.
This image is provided by the National Library of Medicine.

{{#ask: Label Page::Lanolin |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Lanolin in the drug label.

Precautions with Alcohol

  • Alcohol-Lanolin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ "lanolin ointment".
  2. ↑ "http://www.ismp.org". External link in |title= (help)

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