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{{Infobox_gene}}
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'''C-jun-amino-terminal kinase-interacting protein 2''' is a [[protein]] or the name of the [[gene]] that encodes it.<ref name="pmid10490659">{{cite journal |vauthors=Yasuda J, Whitmarsh AJ, Cavanagh J, Sharma M, Davis RJ | title = The JIP Group of Mitogen-Activated Protein Kinase Scaffold Proteins | journal = Mol Cell Biol | volume = 19 | issue = 10 | pages = 7245–54 |date=February 2000 | pmid = 10490659 | pmc = 84717 | doi =  10.1128/mcb.19.10.7245}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23542| accessdate = }}</ref> The gene is also known as Islet-Brain-2 (IB2).
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This protein is highly expressed in the brain and is almost always deleted in [[Phelan-McDermid syndrome]] (PMS). MAPK8IP2 appears to regulate the ratio of [[AMPA receptor]]s to [[NMDA receptor]]s at glutamate synapses,<ref>{{ cite journal |vauthors=Giza J, etal | title= Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2. | journal= J. Neurosci. | volume= 30| issue= 44| pages= 14805–16 | year= 2010 | pmid= 21048139 | doi= 10.1523/JNEUROSCI.1161-10.2010 | pmc=3200367}}</ref> and thus may be an important contributor to the intellectual dysfunction and related neurological manifestations characteristic of PMS.
{{GNF_Protein_box
  | image =
| image_source =
| PDB =
| Name = Mitogen-activated protein kinase 8 interacting protein 2
| HGNCid = 6883
| Symbol = MAPK8IP2
| AltSymbols =; IB2; JIP2; PRKM8IPL
| OMIM = 607755
| ECnumber = 
| Homologene = 8201
| MGIid = 1926555
| GeneAtlas_image1 = PBB_GE_MAPK8IP2_205050_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_MAPK8IP2_208603_s_at_tn.png
| Function = {{GNF_GO|id=GO:0001540 |text = beta-amyloid binding}} {{GNF_GO|id=GO:0005078 |text = MAP-kinase scaffold activity}} {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0019894 |text = kinesin binding}} {{GNF_GO|id=GO:0019901 |text = protein kinase binding}}
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0043025 |text = cell soma}}
| Process = {{GNF_GO|id=GO:0007172 |text = signal complex assembly}} {{GNF_GO|id=GO:0045768 |text = positive regulation of anti-apoptosis}} {{GNF_GO|id=GO:0046328 |text = regulation of JNK cascade}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 23542
    | Hs_Ensembl = ENSG00000008735
    | Hs_RefseqProtein = NP_621713
    | Hs_RefseqmRNA = NM_139124
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 22
    | Hs_GenLoc_start = 49385997
    | Hs_GenLoc_end = 49396842
    | Hs_Uniprot = Q13387
    | Mm_EntrezGene = 60597
    | Mm_Ensembl = ENSMUSG00000022619
    | Mm_RefseqmRNA = NM_021921
    | Mm_RefseqProtein = NP_068740
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 15
    | Mm_GenLoc_start = 89281975
    | Mm_GenLoc_end = 89290671
    | Mm_Uniprot = Q548W8
  }}
}}
'''Mitogen-activated protein kinase 8 interacting protein 2''', also known as '''MAPK8IP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23542| accessdate = }}</ref>


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{{PBB_Summary
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| section_title =  
| section_title =  
| summary_text = The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23542| accessdate = }}</ref>
| summary_text = The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.<ref name="entrez" />
}}
}}
==Interactions==
MAPK8IP2 has been shown to [[Protein-protein interaction|interact]] with [[MAP3K10]],<ref name=pmid10490659 /> [[Mitogen-activated protein kinase 9]],<ref name=pmid10490659/> [[LRP2]],<ref name=pmid10827173>{{cite journal |last=Gotthardt |first=M |authorlink= |author2=Trommsdorff M |author3=Nevitt M F |author4=Shelton J |author5=Richardson J A |author6=Stockinger W |author7=Nimpf J |author8=Herz J  |date=August 2000  |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction |journal=J. Biol. Chem. |volume=275 |issue=33 |pages=25616–24 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10827173 |doi = 10.1074/jbc.M000955200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid12508107>{{cite journal |last=Petersen |first=Helle Heibroch |authorlink= |author2=Hilpert Jan |author3=Militz Daniel |author4=Zandler Valerie |author5=Jacobsen Christian |author6=Roebroek Anton J M |author7=Willnow Thomas E  |date=February 2003  |title=Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule |journal=J. Cell Sci. |volume=116 |issue=Pt 3 |pages=453–61 |publisher= |location = England| issn = 0021-9533| pmid = 12508107 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1242/jcs.00243 }}</ref> [[LRP1]],<ref name=pmid10827173/> [[MAPK8IP3]],<ref name=pmid10629060>{{cite journal |last=Kelkar |first=N |authorlink= |author2=Gupta S |author3=Dickens M |author4=Davis R J  |date=February 2000  |title=Interaction of a Mitogen-Activated Protein Kinase Signaling Module with the Neuronal Protein JIP3 |journal=Mol. Cell. Biol. |volume=20 |issue=3 |pages=1030–43 |publisher= |location = UNITED STATES| issn = 0270-7306| pmid = 10629060 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.20.3.1030-1043.2000 |pmc=85220 }}</ref> [[MAP3K12]],<ref name=pmid10490659/> [[MAPK8IP1]],<ref name=pmid10490659/> [[MAP2K7]]<ref name=pmid10490659/><ref name=pmid10756100>{{cite journal |last=Negri |first=S |authorlink= |author2=Oberson A |author3=Steinmann M |author4=Sauser C |author5=Nicod P |author6=Waeber G |author7=Schorderet D F |author8=Bonny C  |date=March 2000  |title=cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein |journal=Genomics |volume=64 |issue=3 |pages=324–30 |publisher= |location = UNITED STATES| issn = 0888-7543| pmid = 10756100 |doi = 10.1006/geno.2000.6129 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[MAP3K11]].<ref name=pmid10490659/>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal   |vauthors=Andersson B, Wentland MA, Ricafrente JY, etal |title=A "double adaptor" method for improved shotgun library construction |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
*{{cite journal  |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-Scale Concatenation cDNA Sequencing |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=  10.1101/gr.7.4.353| pmc=139146 }}
*{{cite journal  | author=Yasuda J, Whitmarsh AJ, Cavanagh J, ''et al.'' |title=The JIP group of mitogen-activated protein kinase scaffold proteins. |journal=Mol. Cell. Biol. |volume=19 |issue= 10 |pages= 7245-54 |year= 2000 |pmid= 10490659 |doi=  }}
*{{cite journal   |vauthors=Dunham I, Shimizu N, Roe BA, etal |title=The DNA sequence of human chromosome 22 |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 |bibcode=1999Natur.402..489D }}
*{{cite journal | author=Dunham I, Shimizu N, Roe BA, ''et al.'' |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489-95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 }}
*{{cite journal  |vauthors=Kelkar N, Gupta S, Dickens M, Davis RJ |title=Interaction of a Mitogen-Activated Protein Kinase Signaling Module with the Neuronal Protein JIP3 |journal=Mol. Cell. Biol. |volume=20 |issue= 3 |pages= 1030–43 |year= 2000 |pmid= 10629060 |doi=10.1128/MCB.20.3.1030-1043.2000  | pmc=85220 }}
*{{cite journal  | author=Kelkar N, Gupta S, Dickens M, Davis RJ |title=Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. |journal=Mol. Cell. Biol. |volume=20 |issue= 3 |pages= 1030-43 |year= 2000 |pmid= 10629060 |doi=  }}
*{{cite journal   |vauthors=Negri S, Oberson A, Steinmann M, etal |title=cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein |journal=Genomics |volume=64 |issue= 3 |pages= 324–30 |year= 2000 |pmid= 10756100 |doi= 10.1006/geno.2000.6129 }}
*{{cite journal | author=Negri S, Oberson A, Steinmann M, ''et al.'' |title=cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein. |journal=Genomics |volume=64 |issue= 3 |pages= 324-30 |year= 2000 |pmid= 10756100 |doi= 10.1006/geno.2000.6129 }}
*{{cite journal   |vauthors=Gotthardt M, Trommsdorff M, Nevitt MF, etal |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616–24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200 }}
*{{cite journal | author=Gotthardt M, Trommsdorff M, Nevitt MF, ''et al.'' |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616-24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200 }}
*{{cite journal  |vauthors=Schoorlemmer J, Goldfarb M |title=Fibroblast growth factor homologous factors are intracellular signaling proteins |journal=Curr. Biol. |volume=11 |issue= 10 |pages= 793–7 |year= 2001 |pmid= 11378392 |doi=10.1016/S0960-9822(01)00232-9 |pmc=3216481}}
*{{cite journal  | author=Schoorlemmer J, Goldfarb M |title=Fibroblast growth factor homologous factors are intracellular signaling proteins. |journal=Curr. Biol. |volume=11 |issue= 10 |pages= 793-7 |year= 2001 |pmid= 11378392 |doi= }}
*{{cite journal  |vauthors=Taru H, Kirino Y, Suzuki T |title=Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism |journal=J. Biol. Chem. |volume=277 |issue= 30 |pages= 27567–74 |year= 2002 |pmid= 12023290 |doi= 10.1074/jbc.M203713200 }}
*{{cite journal  | author=Taru H, Kirino Y, Suzuki T |title=Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism. |journal=J. Biol. Chem. |volume=277 |issue= 30 |pages= 27567-74 |year= 2002 |pmid= 12023290 |doi= 10.1074/jbc.M203713200 }}
*{{cite journal  |vauthors=Buchsbaum RJ, Connolly BA, Feig LA |title=Interaction of Rac Exchange Factors Tiam1 and Ras-GRF1 with a Scaffold for the p38 Mitogen-Activated Protein Kinase Cascade |journal=Mol. Cell. Biol. |volume=22 |issue= 12 |pages= 4073–85 |year= 2002 |pmid= 12024021 |doi=10.1128/MCB.22.12.4073-4085.2002  | pmc=133864 }}
*{{cite journal  | author=Buchsbaum RJ, Connolly BA, Feig LA |title=Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade. |journal=Mol. Cell. Biol. |volume=22 |issue= 12 |pages= 4073-85 |year= 2002 |pmid= 12024021 |doi=  }}
*{{cite journal  |vauthors=Schoorlemmer J, Goldfarb M |title=Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase |journal=J. Biol. Chem. |volume=277 |issue= 51 |pages= 49111–9 |year= 2003 |pmid= 12244047 |doi= 10.1074/jbc.M205520200 |pmc=4266389 }}
*{{cite journal  | author=Schoorlemmer J, Goldfarb M |title=Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase. |journal=J. Biol. Chem. |volume=277 |issue= 51 |pages= 49111-9 |year= 2003 |pmid= 12244047 |doi= 10.1074/jbc.M205520200 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  |vauthors=Willoughby EA, Perkins GR, Collins MK, Whitmarsh AJ |title=The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK |journal=J. Biol. Chem. |volume=278 |issue= 12 |pages= 10731–6 |year= 2003 |pmid= 12524447 |doi= 10.1074/jbc.M207324200 }}
*{{cite journal  | author=Willoughby EA, Perkins GR, Collins MK, Whitmarsh AJ |title=The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK. |journal=J. Biol. Chem. |volume=278 |issue= 12 |pages= 10731-6 |year= 2003 |pmid= 12524447 |doi= 10.1074/jbc.M207324200 }}
*{{cite journal   |vauthors=Collins JE, Goward ME, Cole CG, etal |title=Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22 |journal=Genome Res. |volume=13 |issue= 1 |pages= 27–36 |year= 2003 |pmid= 12529303 |doi= 10.1101/gr.695703 | pmc=430954 }}
*{{cite journal | author=Collins JE, Goward ME, Cole CG, ''et al.'' |title=Reevaluating human gene annotation: a second-generation analysis of chromosome 22. |journal=Genome Res. |volume=13 |issue= 1 |pages= 27-36 |year= 2003 |pmid= 12529303 |doi= 10.1101/gr.695703 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Kristensen O, Guenat S, Dar I, etal |title=A unique set of SH3–SH3 interactions controls IB1 homodimerization |journal=EMBO J. |volume=25 |issue= 4 |pages= 785–97 |year= 2006 |pmid= 16456539 |doi= 10.1038/sj.emboj.7600982 | pmc=1383563 }}
*{{cite journal | author=Kristensen O, Guenat S, Dar I, ''et al.'' |title=A unique set of SH3-SH3 interactions controls IB1 homodimerization. |journal=EMBO J. |volume=25 |issue= 4 |pages= 785-97 |year= 2006 |pmid= 16456539 |doi= 10.1038/sj.emboj.7600982 }}
}}
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Latest revision as of 12:26, 9 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Wikidata
View/Edit Human

C-jun-amino-terminal kinase-interacting protein 2 is a protein or the name of the gene that encodes it.[1][2] The gene is also known as Islet-Brain-2 (IB2).

This protein is highly expressed in the brain and is almost always deleted in Phelan-McDermid syndrome (PMS). MAPK8IP2 appears to regulate the ratio of AMPA receptors to NMDA receptors at glutamate synapses,[3] and thus may be an important contributor to the intellectual dysfunction and related neurological manifestations characteristic of PMS.

The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.[2]

Interactions

MAPK8IP2 has been shown to interact with MAP3K10,[1] Mitogen-activated protein kinase 9,[1] LRP2,[4][5] LRP1,[4] MAPK8IP3,[6] MAP3K12,[1] MAPK8IP1,[1] MAP2K7[1][7] and MAP3K11.[1]

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Yasuda J, Whitmarsh AJ, Cavanagh J, Sharma M, Davis RJ (February 2000). "The JIP Group of Mitogen-Activated Protein Kinase Scaffold Proteins". Mol Cell Biol. 19 (10): 7245–54. doi:10.1128/mcb.19.10.7245. PMC 84717. PMID 10490659.
  2. ↑ 2.0 2.1 "Entrez Gene: MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2".
  3. ↑ Giza J, et al. (2010). "Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2". J. Neurosci. 30 (44): 14805–16. doi:10.1523/JNEUROSCI.1161-10.2010. PMC 3200367. PMID 21048139.
  4. ↑ 4.0 4.1 Gotthardt, M; Trommsdorff M; Nevitt M F; Shelton J; Richardson J A; Stockinger W; Nimpf J; Herz J (August 2000). "Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction". J. Biol. Chem. UNITED STATES. 275 (33): 25616–24. doi:10.1074/jbc.M000955200. ISSN 0021-9258. PMID 10827173.
  5. ↑ Petersen, Helle Heibroch; Hilpert Jan; Militz Daniel; Zandler Valerie; Jacobsen Christian; Roebroek Anton J M; Willnow Thomas E (February 2003). "Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule". J. Cell Sci. England. 116 (Pt 3): 453–61. doi:10.1242/jcs.00243. ISSN 0021-9533. PMID 12508107.
  6. ↑ Kelkar, N; Gupta S; Dickens M; Davis R J (February 2000). "Interaction of a Mitogen-Activated Protein Kinase Signaling Module with the Neuronal Protein JIP3". Mol. Cell. Biol. UNITED STATES. 20 (3): 1030–43. doi:10.1128/MCB.20.3.1030-1043.2000. ISSN 0270-7306. PMC 85220. PMID 10629060.
  7. ↑ Negri, S; Oberson A; Steinmann M; Sauser C; Nicod P; Waeber G; Schorderet D F; Bonny C (March 2000). "cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein". Genomics. UNITED STATES. 64 (3): 324–30. doi:10.1006/geno.2000.6129. ISSN 0888-7543. PMID 10756100.

Further reading



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