RAB10: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Ras-related protein Rab-10''' is a [[protein]] that in humans is encoded by the ''RAB10'' [[gene]].<ref name="pmid7688123">{{cite journal | vauthors = Chen YT, Holcomb C, Moore HP | title = Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 90 | issue = 14 | pages = 6508–12 | date = Jul 1993 | pmid = 7688123 | pmc = 46961 | doi = 10.1073/pnas.90.14.6508 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB10 RAB10, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10890| accessdate = }}</ref>
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== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = RAB10, member RAS oncogene family
| HGNCid = 9759
| Symbol = RAB10
| AltSymbols =;
| OMIM = 
| ECnumber = 
| Homologene = 41111
| MGIid = 105066
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10890
    | Hs_Ensembl = ENSG00000084733
    | Hs_RefseqProtein = NP_057215
    | Hs_RefseqmRNA = NM_016131
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 26110483
    | Hs_GenLoc_end = 26213827
    | Hs_Uniprot = P61026
    | Mm_EntrezGene = 19325
    | Mm_Ensembl = ENSMUSG00000020671
    | Mm_RefseqmRNA = NM_016676
    | Mm_RefseqProtein = NP_057885
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 3247726
    | Mm_GenLoc_end = 3309939
    | Mm_Uniprot = Q3U621
  }}
}}
'''RAB10, member RAS oncogene family''', also known as '''RAB10''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB10 RAB10, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10890| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
RAB10 has been shown to [[Protein-protein_interaction|interact]] with [[AP1S1]].<ref name=pmid17353931>{{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}</ref>
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| summary_text =  
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==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Bao S, Zhu J, Garvey WT | title = Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects | journal = Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme | volume = 30 | issue = 11 | pages = 656–62 | date = Nov 1998 | pmid = 9918381 | doi = 10.1055/s-2007-978953 }}
| citations =
* {{cite journal | vauthors = Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL | title = Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 17 | pages = 9543–8 | date = Aug 2000 | pmid = 10931946 | pmc = 16901 | doi = 10.1073/pnas.160270997 }}
*{{cite journal  | author=Chen YT, Holcomb C, Moore HP |title=Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 14 |pages= 6508-12 |year= 1993 |pmid= 7688123 |doi=  }}
* {{cite journal | vauthors = Fukuda M | title = Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 17 | pages = 15373–80 | date = Apr 2003 | pmid = 12578829 | doi = 10.1074/jbc.M212341200 }}
*{{cite journal | author=Bao S, Zhu J, Garvey WT |title=Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects. |journal=Horm. Metab. Res. |volume=30 |issue= 11 |pages= 656-62 |year= 1999 |pmid= 9918381 |doi= }}
* {{cite journal | vauthors = Sonkoly E, Bata-Csorgo Z, Pivarcsi A, Polyanka H, Kenderessy-Szabo A, Molnar G, Szentpali K, Bari L, Megyeri K, Mandi Y, Dobozy A, Kemeny L, Szell M | title = Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS | journal = The Journal of Biological Chemistry | volume = 280 | issue = 25 | pages = 24159–67 | date = Jun 2005 | pmid = 15855153 | doi = 10.1074/jbc.M501704200 }}
*{{cite journal | author=Hu RM, Han ZG, Song HD, ''et al.'' |title=Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 17 |pages= 9543-8 |year= 2000 |pmid= 10931946 |doi= 10.1073/pnas.160270997 }}
* {{cite journal | vauthors = Larance M, Ramm G, Stöckli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M, James DE | title = Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking | journal = The Journal of Biological Chemistry | volume = 280 | issue = 45 | pages = 37803–13 | date = Nov 2005 | pmid = 16154996 | doi = 10.1074/jbc.M503897200 }}
*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Fukuda M |title=Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. |journal=J. Biol. Chem. |volume=278 |issue= 17 |pages= 15373-80 |year= 2003 |pmid= 12578829 |doi= 10.1074/jbc.M212341200 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Sonkoly E, Bata-Csorgo Z, Pivarcsi A, ''et al.'' |title=Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS. |journal=J. Biol. Chem. |volume=280 |issue= 25 |pages= 24159-67 |year= 2005 |pmid= 15855153 |doi= 10.1074/jbc.M501704200 }}
*{{cite journal | author=Larance M, Ramm G, Stöckli J, ''et al.'' |title=Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. |journal=J. Biol. Chem. |volume=280 |issue= 45 |pages= 37803-13 |year= 2006 |pmid= 16154996 |doi= 10.1074/jbc.M503897200 }}
*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 03:21, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

n/a

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene.[1][2]

Interactions

RAB10 has been shown to interact with AP1S1.[3]

References

  1. ↑ Chen YT, Holcomb C, Moore HP (Jul 1993). "Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag". Proceedings of the National Academy of Sciences of the United States of America. 90 (14): 6508–12. doi:10.1073/pnas.90.14.6508. PMC 46961. PMID 7688123.
  2. ↑ "Entrez Gene: RAB10 RAB10, member RAS oncogene family".
  3. ↑ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

Further reading

  • Bao S, Zhu J, Garvey WT (Nov 1998). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme. 30 (11): 656–62. doi:10.1055/s-2007-978953. PMID 9918381.
  • Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (Aug 2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
  • Fukuda M (Apr 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". The Journal of Biological Chemistry. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
  • Sonkoly E, Bata-Csorgo Z, Pivarcsi A, Polyanka H, Kenderessy-Szabo A, Molnar G, Szentpali K, Bari L, Megyeri K, Mandi Y, Dobozy A, Kemeny L, Szell M (Jun 2005). "Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS". The Journal of Biological Chemistry. 280 (25): 24159–67. doi:10.1074/jbc.M501704200. PMID 15855153.
  • Larance M, Ramm G, Stöckli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M, James DE (Nov 2005). "Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking". The Journal of Biological Chemistry. 280 (45): 37803–13. doi:10.1074/jbc.M503897200. PMID 16154996.
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