RAB21: Difference between revisions

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{{Infobox_gene}}
{{GNF_Protein_box
'''Ras-related protein Rab-21''' is a [[protein]] that in humans is encoded by the ''RAB21'' [[gene]].<ref name="pmid10887961">{{cite journal | vauthors = Opdam FJ, Kamps G, Croes H, van Bokhoven H, Ginsel LA, Fransen JA | title = Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells | journal = Eur J Cell Biol | volume = 79 | issue = 5 | pages = 308–16 |date=Oct 2000 | pmid = 10887961 | pmc =  | doi =10.1078/S0171-9335(04)70034-5 }}</ref><ref name="pmid11697911">{{cite journal | vauthors = Pereira-Leal JB, Seabra MC | title = Evolution of the Rab family of small GTP-binding proteins | journal = J Mol Biol | volume = 313 | issue = 4 | pages = 889–901 |date=Nov 2001 | pmid = 11697911 | pmc = | doi = 10.1006/jmbi.2001.5072 }}</ref><ref name="pmid16754960">{{cite journal | vauthors = Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J | title = Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins | journal = J Cell Biol | volume = 173 | issue = 5 | pages = 767–80 |date=Jun 2006 | pmid = 16754960 | pmc = 2063892 | doi = 10.1083/jcb.200509019 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB21 RAB21, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23011| accessdate = }}</ref>
| image = PBB_Protein_RAB21_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1yzt.
| PDB = {{PDB2|1yzt}}, {{PDB2|1yzu}}, {{PDB2|1z08}}, {{PDB2|1z0i}}, {{PDB2|2ot3}}
| Name = RAB21, member RAS oncogene family
| HGNCid = 18263
| Symbol = RAB21
| AltSymbols =; KIAA0118
| OMIM =
| ECnumber =
| Homologene = 8991
| MGIid = 894308
| GeneAtlas_image1 = PBB_GE_RAB21_203885_at_tn.png
  | GeneAtlas_image2 = PBB_GE_RAB21_gnf1h10035_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005768 |text = endosome}}
| Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 23011
    | Hs_Ensembl = ENSG00000080371
    | Hs_RefseqProtein = NP_055814
    | Hs_RefseqmRNA = NM_014999
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 70434925
    | Hs_GenLoc_end = 70467417
    | Hs_Uniprot = Q9UL25
    | Mm_EntrezGene = 216344
    | Mm_Ensembl = ENSMUSG00000020132
    | Mm_RefseqmRNA = NM_024454
    | Mm_RefseqProtein = NP_077774
    | Mm_GenLoc_db =
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 114693972
    | Mm_GenLoc_end = 114719701
    | Mm_Uniprot = Q0PD35
  }}
}}
'''RAB21, member RAS oncogene family''', also known as '''RAB21''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB21 RAB21, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23011| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Nagase T, Miyajima N, Tanaka A, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=2 |issue= 1 |pages= 37-43 |year= 1995 |pmid= 7788527 |doi=  }}
*{{cite journal   |vauthors=Nagase T, Miyajima N, Tanaka A, etal |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 |journal=DNA Res. |volume=2 |issue= 1 |pages= 37–43 |year= 1995 |pmid= 7788527 |doi=10.1093/dnares/2.1.37 }}
*{{cite journal  | author=Bao S, Zhu J, Garvey WT |title=Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects. |journal=Horm. Metab. Res. |volume=30 |issue= 11 |pages= 656-62 |year= 1999 |pmid= 9918381 |doi= }}
*{{cite journal  | vauthors=Bao S, Zhu J, Garvey WT |title=Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects |journal=Horm. Metab. Res. |volume=30 |issue= 11 |pages= 656–62 |year= 1999 |pmid= 9918381 |doi=10.1055/s-2007-978953 }}
*{{cite journal  | author=Opdam FJ, Kamps G, Croes H, ''et al.'' |title=Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells. |journal=Eur. J. Cell Biol. |volume=79 |issue= 5 |pages= 308-16 |year= 2000 |pmid= 10887961 |doi= }}
*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948 }}
*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
*{{cite journal   |vauthors=Simpson JC, Wellenreuther R, Poustka A, etal |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058  | pmc=1083732 }}
*{{cite journal | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Pereira-Leal JB, Seabra MC |title=Evolution of the Rab family of small GTP-binding proteins. |journal=J. Mol. Biol. |volume=313 |issue= 4 |pages= 889-901 |year= 2001 |pmid= 11697911 |doi= 10.1006/jmbi.2001.5072 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006 |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139  | pmc=1347501 }}
*{{cite journal | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
*{{cite journal | author=Pellinen T, Arjonen A, Vuoriluoto K, ''et al.'' |title=Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins. |journal=J. Cell Biol. |volume=173 |issue= 5 |pages= 767-80 |year= 2006 |pmid= 16754960 |doi= 10.1083/jcb.200509019 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=23011}}
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{{gene-12-stub}}
{{gene-12-stub}}
{{WikiDoc Sources}}

Latest revision as of 15:39, 19 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene.[1][2][3][4]


References

  1. Opdam FJ, Kamps G, Croes H, van Bokhoven H, Ginsel LA, Fransen JA (Oct 2000). "Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells". Eur J Cell Biol. 79 (5): 308–16. doi:10.1078/S0171-9335(04)70034-5. PMID 10887961.
  2. Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
  3. Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J (Jun 2006). "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins". J Cell Biol. 173 (5): 767–80. doi:10.1083/jcb.200509019. PMC 2063892. PMID 16754960.
  4. "Entrez Gene: RAB21 RAB21, member RAS oncogene family".

Further reading