RPH3AL: Difference between revisions
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{{ | '''Rab effector Noc2''' is a [[protein]] that in humans is encoded by the ''RPH3AL'' [[gene]].<ref name="pmid10395805">{{cite journal | vauthors = Smith JS, Tachibana I, Allen C, Chiappa SA, Lee HK, McIver B, Jenkins RB, Raffel C | title = Cloning of a human ortholog (RPH3AL) of (RNO)Rph3al from a candidate 17p13.3 medulloblastoma tumor suppressor locus | journal = Genomics | volume = 59 | issue = 1 | pages = 97–101 | date = July 1999 | pmid = 10395805 | pmc = | doi = 10.1006/geno.1999.5864 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RPH3AL rabphilin 3A-like (without C2 domains)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9501| accessdate = }}</ref> | ||
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== Interactions == | |||
< | RPH3AL has been shown to [[Protein-protein interaction|interact]] with [[RAB27A]].<ref name=pmid14593078>{{cite journal | vauthors = Cheviet S, Coppola T, Haynes LP, Burgoyne RD, Regazzi R | title = The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis | journal = Molecular Endocrinology | volume = 18 | issue = 1 | pages = 117–26 | date = January 2004 | pmid = 14593078 | doi = 10.1210/me.2003-0300 }}</ref><ref name=pmid12578829>{{cite journal | vauthors = Fukuda M | title = Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 17 | pages = 15373–80 | date = April 2003 | pmid = 12578829 | doi = 10.1074/jbc.M212341200 }}</ref> | ||
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==References== | == References == | ||
{{reflist | {{reflist}} | ||
==Further reading== | |||
== Further reading == | |||
{{refbegin | 2}} | {{refbegin | 2}} | ||
* {{cite journal | vauthors = Kotake K, Ozaki N, Mizuta M, Sekiya S, Inagaki N, Seino S | title = Noc2, a putative zinc finger protein involved in exocytosis in endocrine cells | journal = The Journal of Biological Chemistry | volume = 272 | issue = 47 | pages = 29407–10 | date = November 1997 | pmid = 9367993 | doi = 10.1074/jbc.272.47.29407 }} | |||
* {{cite journal | vauthors = Fenster SD, Chung WJ, Zhai R, Cases-Langhoff C, Voss B, Garner AM, Kaempf U, Kindler S, Gundelfinger ED, Garner CC | title = Piccolo, a presynaptic zinc finger protein structurally related to bassoon | journal = Neuron | volume = 25 | issue = 1 | pages = 203–14 | date = January 2000 | pmid = 10707984 | doi = 10.1016/S0896-6273(00)80883-1 }} | |||
*{{cite journal | * {{cite journal | vauthors = Haynes LP, Evans GJ, Morgan A, Burgoyne RD | title = A direct inhibitory role for the Rab3-specific effector, Noc2, in Ca2+-regulated exocytosis in neuroendocrine cells | journal = The Journal of Biological Chemistry | volume = 276 | issue = 13 | pages = 9726–32 | date = March 2001 | pmid = 11134008 | doi = 10.1074/jbc.M006959200 }} | ||
* {{cite journal | vauthors = Goi T, Takeuchi K, Katayama K, Hirose K, Yamaguchi A | title = Mutations of rabphillin-3A-like gene in colorectal cancers | journal = Oncology Reports | volume = 9 | issue = 6 | pages = 1189–92 | year = 2003 | pmid = 12375017 | doi = 10.3892/or.9.6.1189 }} | |||
*{{cite journal | * {{cite journal | vauthors = Milkereit P, Strauss D, Bassler J, Gadal O, Kühn H, Schütz S, Gas N, Lechner J, Hurt E, Tschochner H | title = A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits | journal = The Journal of Biological Chemistry | volume = 278 | issue = 6 | pages = 4072–81 | date = February 2003 | pmid = 12446671 | doi = 10.1074/jbc.M208898200 }} | ||
*{{cite journal | * {{cite journal | vauthors = Fukuda M | title = Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 17 | pages = 15373–80 | date = April 2003 | pmid = 12578829 | doi = 10.1074/jbc.M212341200 }} | ||
*{{cite journal | * {{cite journal | vauthors = Cardoso C, Leventer RJ, Ward HL, Toyo-Oka K, Chung J, Gross A, Martin CL, Allanson J, Pilz DT, Olney AH, Mutchinick OM, Hirotsune S, Wynshaw-Boris A, Dobyns WB, Ledbetter DH | title = Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3 | journal = American Journal of Human Genetics | volume = 72 | issue = 4 | pages = 918–30 | date = April 2003 | pmid = 12621583 | pmc = 1180354 | doi = 10.1086/374320 }} | ||
*{{cite journal | * {{cite journal | vauthors = Cheviet S, Coppola T, Haynes LP, Burgoyne RD, Regazzi R | title = The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis | journal = Molecular Endocrinology | volume = 18 | issue = 1 | pages = 117–26 | date = January 2004 | pmid = 14593078 | doi = 10.1210/me.2003-0300 }} | ||
*{{cite journal | * {{cite journal | vauthors = Manabe S, Nishimura N, Yamamoto Y, Kitamura H, Morimoto S, Imai M, Nagahiro S, Seino S, Sasaki T | title = Identification and characterization of Noc2 as a potential Rab3B effector protein in epithelial cells | journal = Biochemical and Biophysical Research Communications | volume = 316 | issue = 1 | pages = 218–25 | date = March 2004 | pmid = 15003533 | doi = 10.1016/j.bbrc.2004.02.026 }} | ||
* {{cite journal | vauthors = Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, Seino S | title = Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 22 | pages = 8313–8 | date = June 2004 | pmid = 15159548 | pmc = 420391 | doi = 10.1073/pnas.0306709101 }} | |||
*{{cite journal | * {{cite journal | vauthors = Katkoori VR, Jia X, Chatla C, Kumar S, Ponnazhagan S, Callens T, Messiaen L, Grizzle WE, Manne U | title = Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinoma | journal = Frontiers in Bioscience | volume = 13 | issue = 1 | pages = 1050–61 | date = January 2008 | pmid = 17981610 | pmc = 2667692 | doi = 10.2741/2742 }} | ||
*{{cite journal | |||
*{{cite journal | |||
*{{cite journal | |||
*{{cite journal | |||
}} | |||
{{refend}} | {{refend}} | ||
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Rab effector Noc2 is a protein that in humans is encoded by the RPH3AL gene.[1][2]
Interactions
RPH3AL has been shown to interact with RAB27A.[3][4]
References
- ↑ Smith JS, Tachibana I, Allen C, Chiappa SA, Lee HK, McIver B, Jenkins RB, Raffel C (July 1999). "Cloning of a human ortholog (RPH3AL) of (RNO)Rph3al from a candidate 17p13.3 medulloblastoma tumor suppressor locus". Genomics. 59 (1): 97–101. doi:10.1006/geno.1999.5864. PMID 10395805.
- ↑ "Entrez Gene: RPH3AL rabphilin 3A-like (without C2 domains)".
- ↑ Cheviet S, Coppola T, Haynes LP, Burgoyne RD, Regazzi R (January 2004). "The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis". Molecular Endocrinology. 18 (1): 117–26. doi:10.1210/me.2003-0300. PMID 14593078.
- ↑ Fukuda M (April 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". The Journal of Biological Chemistry. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
Further reading
- Kotake K, Ozaki N, Mizuta M, Sekiya S, Inagaki N, Seino S (November 1997). "Noc2, a putative zinc finger protein involved in exocytosis in endocrine cells". The Journal of Biological Chemistry. 272 (47): 29407–10. doi:10.1074/jbc.272.47.29407. PMID 9367993.
- Fenster SD, Chung WJ, Zhai R, Cases-Langhoff C, Voss B, Garner AM, Kaempf U, Kindler S, Gundelfinger ED, Garner CC (January 2000). "Piccolo, a presynaptic zinc finger protein structurally related to bassoon". Neuron. 25 (1): 203–14. doi:10.1016/S0896-6273(00)80883-1. PMID 10707984.
- Haynes LP, Evans GJ, Morgan A, Burgoyne RD (March 2001). "A direct inhibitory role for the Rab3-specific effector, Noc2, in Ca2+-regulated exocytosis in neuroendocrine cells". The Journal of Biological Chemistry. 276 (13): 9726–32. doi:10.1074/jbc.M006959200. PMID 11134008.
- Goi T, Takeuchi K, Katayama K, Hirose K, Yamaguchi A (2003). "Mutations of rabphillin-3A-like gene in colorectal cancers". Oncology Reports. 9 (6): 1189–92. doi:10.3892/or.9.6.1189. PMID 12375017.
- Milkereit P, Strauss D, Bassler J, Gadal O, Kühn H, Schütz S, Gas N, Lechner J, Hurt E, Tschochner H (February 2003). "A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits". The Journal of Biological Chemistry. 278 (6): 4072–81. doi:10.1074/jbc.M208898200. PMID 12446671.
- Fukuda M (April 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". The Journal of Biological Chemistry. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
- Cardoso C, Leventer RJ, Ward HL, Toyo-Oka K, Chung J, Gross A, Martin CL, Allanson J, Pilz DT, Olney AH, Mutchinick OM, Hirotsune S, Wynshaw-Boris A, Dobyns WB, Ledbetter DH (April 2003). "Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3". American Journal of Human Genetics. 72 (4): 918–30. doi:10.1086/374320. PMC 1180354. PMID 12621583.
- Cheviet S, Coppola T, Haynes LP, Burgoyne RD, Regazzi R (January 2004). "The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis". Molecular Endocrinology. 18 (1): 117–26. doi:10.1210/me.2003-0300. PMID 14593078.
- Manabe S, Nishimura N, Yamamoto Y, Kitamura H, Morimoto S, Imai M, Nagahiro S, Seino S, Sasaki T (March 2004). "Identification and characterization of Noc2 as a potential Rab3B effector protein in epithelial cells". Biochemical and Biophysical Research Communications. 316 (1): 218–25. doi:10.1016/j.bbrc.2004.02.026. PMID 15003533.
- Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, Seino S (June 2004). "Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells". Proceedings of the National Academy of Sciences of the United States of America. 101 (22): 8313–8. doi:10.1073/pnas.0306709101. PMC 420391. PMID 15159548.
- Katkoori VR, Jia X, Chatla C, Kumar S, Ponnazhagan S, Callens T, Messiaen L, Grizzle WE, Manne U (January 2008). "Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinoma". Frontiers in Bioscience. 13 (1): 1050–61. doi:10.2741/2742. PMC 2667692. PMID 17981610.
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