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{{Infobox_gene}}
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'''Protein SEC13 homolog''' is a [[protein]] that in humans is encoded by the ''SEC13'' [[gene]].<ref name="pmid7987303">{{cite journal | vauthors = Swaroop A, Yang-Feng TL, Liu W, Gieser L, Barrow LL, Chen KC, Agarwal N, Meisler MH, Smith DI | title = Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6 | journal = Hum Mol Genet | volume = 3 | issue = 8 | pages = 1281–6 |date=Jan 1995 | pmid = 7987303 | pmc =  | doi =10.1093/hmg/3.8.1281 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SEC13 SEC13 homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6396| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = SEC13 homolog (S. cerevisiae)
| HGNCid = 10697
| Symbol = SEC13
| AltSymbols =; D3S1231E; SEC13L1; SEC13R
| OMIM = 600152
| ECnumber =
| Homologene = 6479
| MGIid = 99832
  | GeneAtlas_image1 = PBB_GE_SEC13_207707_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component =
| Process = {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6396
    | Hs_Ensembl = ENSG00000157020
    | Hs_RefseqProtein = NP_109598
    | Hs_RefseqmRNA = NM_030673
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 10317215
    | Hs_GenLoc_end = 10337862
    | Hs_Uniprot = P55735
    | Mm_EntrezGene = 110379
    | Mm_Ensembl = ENSMUSG00000030298
    | Mm_RefseqmRNA = NM_024206
    | Mm_RefseqProtein = NP_077168
    | Mm_GenLoc_db =  
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 113694127
    | Mm_GenLoc_end = 113703775
    | Mm_Uniprot = Q9D1M0
  }}
}}
'''SEC13 homolog (S. cerevisiae)''', also known as '''SEC13''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SEC13 SEC13 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6396| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins.<ref name="entrez">{{cite web | title = Entrez Gene: SEC13 SEC13 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6396| accessdate = }}</ref>
| summary_text = The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It has similarity to the yeast SEC13 and [[SEC31]] proteins, which are required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins.<ref name="entrez" />
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Shaywitz DA, Orci L, Ravazzola M, ''et al.'' |title=Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum. |journal=J. Cell Biol. |volume=128 |issue= 5 |pages= 769-77 |year= 1995 |pmid= 7876304 |doi= }}
*{{cite journal   |vauthors=Shaywitz DA, Orci L, Ravazzola M, etal |title=Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum. |journal=J. Cell Biol. |volume=128 |issue= 5 |pages= 769–77 |year= 1995 |pmid= 7876304 |doi=10.1083/jcb.128.5.769  | pmc=2120388 }}
*{{cite journal  | author=Swaroop A, Yang-Feng TL, Liu W, ''et al.'' |title=Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6. |journal=Hum. Mol. Genet. |volume=3 |issue= 8 |pages= 1281-6 |year= 1995 |pmid= 7987303 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal   |vauthors=Andersson B, Wentland MA, Ricafrente JY, etal |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | vauthors=Mammoto A, Sasaki T, Kim Y, Takai Y |title=Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13167–70 |year= 2000 |pmid= 10747849 |doi=10.1074/jbc.C000096200 }}
*{{cite journal  | author=Mammoto A, Sasaki T, Kim Y, Takai Y |title=Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13167-70 |year= 2000 |pmid= 10747849 |doi=  }}
*{{cite journal   |vauthors=Tang BL, Zhang T, Low DY, etal |title=Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13597–604 |year= 2000 |pmid= 10788476 |doi=10.1074/jbc.275.18.13597 }}
*{{cite journal | author=Tang BL, Zhang T, Low DY, ''et al.'' |title=Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13597-604 |year= 2000 |pmid= 10788476 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Gevaert K, Goethals M, Martens L, etal |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
*{{cite journal | author=Gevaert K, Goethals M, Martens L, ''et al.'' |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566-9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
*{{cite journal  | vauthors=Enninga J, Levay A, Fontoura BM |title=Sec13 shuttles between the nucleus and the cytoplasm and stably interacts with Nup96 at the nuclear pore complex. |journal=Mol. Cell. Biol. |volume=23 |issue= 20 |pages= 7271–84 |year= 2003 |pmid= 14517296 |doi=10.1128/MCB.23.20.7271-7284.2003  | pmc=230331 }}
*{{cite journal  | author=Enninga J, Levay A, Fontoura BM |title=Sec13 shuttles between the nucleus and the cytoplasm and stably interacts with Nup96 at the nuclear pore complex. |journal=Mol. Cell. Biol. |volume=23 |issue= 20 |pages= 7271-84 |year= 2003 |pmid= 14517296 |doi=  }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Bouwmeester T, Bauch A, Ruffner H, etal |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal   |vauthors=Loïodice I, Alves A, Rabut G, etal |title=The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. |journal=Mol. Biol. Cell |volume=15 |issue= 7 |pages= 3333–44 |year= 2005 |pmid= 15146057 |doi= 10.1091/mbc.E03-12-0878 | pmc=452587 }}
*{{cite journal | author=Loïodice I, Alves A, Rabut G, ''et al.'' |title=The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. |journal=Mol. Biol. Cell |volume=15 |issue= 7 |pages= 3333-44 |year= 2005 |pmid= 15146057 |doi= 10.1091/mbc.E03-12-0878 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Stagg SM, Gürkan C, Fowler DM, etal |title=Structure of the Sec13/31 COPII coat cage. |journal=Nature |volume=439 |issue= 7073 |pages= 234–8 |year= 2006 |pmid= 16407955 |doi= 10.1038/nature04339 }}
*{{cite journal | author=Stagg SM, Gürkan C, Fowler DM, ''et al.'' |title=Structure of the Sec13/31 COPII coat cage. |journal=Nature |volume=439 |issue= 7073 |pages= 234-8 |year= 2006 |pmid= 16407955 |doi= 10.1038/nature04339 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
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[[Category:Nuclear pore complex]]

Latest revision as of 06:03, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene.[1][2]

The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It has similarity to the yeast SEC13 and SEC31 proteins, which are required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins.[2]

References

  1. ↑ Swaroop A, Yang-Feng TL, Liu W, Gieser L, Barrow LL, Chen KC, Agarwal N, Meisler MH, Smith DI (Jan 1995). "Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6". Hum Mol Genet. 3 (8): 1281–6. doi:10.1093/hmg/3.8.1281. PMID 7987303.
  2. ↑ 2.0 2.1 "Entrez Gene: SEC13 SEC13 homolog (S. cerevisiae)".

Further reading



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