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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Septin-4''' is a [[protein]] that in humans is encoded by the ''SEPT4'' [[gene]].<ref name="pmid9889007">{{cite journal | vauthors = Paavola P, Horelli-Kuitunen N, Palotie A, Peltonen L | title = Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene | journal = Genomics | volume = 55 | issue = 1 | pages = 122–5 | date = January 1999 | pmid = 9889007 | pmc =  | doi = 10.1006/geno.1998.5612 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SEPT4 septin 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5414| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Septin 4
| HGNCid = 9165
| Symbol = SEPT4
| AltSymbols =; H5; ARTS; CE5B3; PNUTL2; hCDCREL-2; hucep-7
| OMIM = 603696
| ECnumber = 
| Homologene = 6107
| MGIid = 1270156
| GeneAtlas_image1 = PBB_GE_SEPT4_210657_s_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003924 |text = GTPase activity}} {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}}
| Process = {{GNF_GO|id=GO:0000910 |text = cytokinesis}} {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0042981 |text = regulation of apoptosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 5414
    | Hs_Ensembl = ENSG00000108387
    | Hs_RefseqProtein = NP_004565
    | Hs_RefseqmRNA = NM_004574
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 53952615
    | Hs_GenLoc_end = 53964410
    | Hs_Uniprot = O43236
    | Mm_EntrezGene = 18952
    | Mm_Ensembl = ENSMUSG00000020486
    | Mm_RefseqmRNA = NM_011129
    | Mm_RefseqProtein = NP_035259
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 87382997
    | Mm_GenLoc_end = 87406734
    | Mm_Uniprot = Q3UVH1
  }}
}}
'''Septin 4''', also known as '''SEPT4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SEPT4 septin 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5414| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene is a member of the [[septin]] gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. The protein encoded by this gene is thought to be part of a complex involved in [[cytokinesis]]. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. The protein encoded by this gene is thought to be part of a complex involved in cytokinesis. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.<ref name="entrez">{{cite web | title = Entrez Gene: SEPT4 septin 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5414| accessdate = }}</ref>
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Xie H, Surka M, Howard J, Trimble WS | title = Characterization of the mammalian septin H5: distinct patterns of cytoskeletal and membrane association from other septin proteins | journal = Cell Motility and the Cytoskeleton | volume = 43 | issue = 1 | pages = 52–62 | year = 1999 | pmid = 10340703 | doi = 10.1002/(SICI)1097-0169(1999)43:1<52::AID-CM6>3.0.CO;2-5 }}
| citations =
* {{cite journal | vauthors = Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, Gottfried Y, Birkey Reffey S, de Caestecker MP, Danielpour D, Book-Melamed N, Timberg R, Duckett CS, Lechleider RJ, Steller H, Orly J, Kim SJ, Roberts AB | title = A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif | journal = Nature Cell Biology | volume = 2 | issue = 12 | pages = 915–21 | date = December 2000 | pmid = 11146656 | doi = 10.1038/35046566 }}
*{{cite journal | author=Paavola P, Horelli-Kuitunen N, Palotie A, Peltonen L |title=Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene. |journal=Genomics |volume=55 |issue= 1 |pages= 122-5 |year= 1999 |pmid= 9889007 |doi= 10.1006/geno.1998.5612 }}
* {{cite journal | vauthors = Zieger B, Tran H, Hainmann I, Wunderle D, Zgaga-Griesz A, Blaser S, Ware J | title = Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2 | journal = Gene | volume = 261 | issue = 2 | pages = 197–203 | date = December 2000 | pmid = 11167005 | doi = 10.1016/S0378-1119(00)00527-8 }}
*{{cite journal  | author=Xie H, Surka M, Howard J, Trimble WS |title=Characterization of the mammalian septin H5: distinct patterns of cytoskeletal and membrane association from other septin proteins. |journal=Cell Motil. Cytoskeleton |volume=43 |issue= 1 |pages= 52-62 |year= 1999 |pmid= 10340703 |doi= 10.1002/(SICI)1097-0169(1999)43:1<52::AID-CM6>3.0.CO;2-5 }}
* {{cite journal | vauthors = Tanaka M, Tanaka T, Kijima H, Itoh J, Matsuda T, Hori S, Yamamoto M | title = Characterization of tissue- and cell-type-specific expression of a novel human septin family gene, Bradeion | journal = Biochemical and Biophysical Research Communications | volume = 286 | issue = 3 | pages = 547–53 | date = August 2001 | pmid = 11511094 | doi = 10.1006/bbrc.2001.5413 }}
*{{cite journal | author=Larisch S, Yi Y, Lotan R, ''et al.'' |title=A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. |journal=Nat. Cell Biol. |volume=2 |issue= 12 |pages= 915-21 |year= 2001 |pmid= 11146656 |doi= 10.1038/35046566 }}
* {{cite journal | vauthors = Tanaka M, Kijima H, Itoh J, Matsuda T, Tanaka T | title = Impaired expression of a human septin family gene Bradeion inhibits the growth and tumorigenesis of colorectal cancer in vitro and in vivo | journal = Cancer Gene Therapy | volume = 9 | issue = 6 | pages = 483–8 | date = June 2002 | pmid = 12032658 | doi = 10.1038/sj.cgt.7700460 }}
*{{cite journal | author=Zieger B, Tran H, Hainmann I, ''et al.'' |title=Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2. |journal=Gene |volume=261 |issue= 2 |pages= 197-203 |year= 2001 |pmid= 11167005 |doi= }}
* {{cite journal | vauthors = Vega IE, Hsu SC | title = The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells | journal = NeuroReport | volume = 14 | issue = 1 | pages = 31–7 | date = January 2003 | pmid = 12544826 | doi = 10.1097/01.wnr.0000050304.92401.50 }}
*{{cite journal | author=Tanaka M, Tanaka T, Kijima H, ''et al.'' |title=Characterization of tissue- and cell-type-specific expression of a novel human septin family gene, Bradeion. |journal=Biochem. Biophys. Res. Commun. |volume=286 |issue= 3 |pages= 547-53 |year= 2001 |pmid= 11511094 |doi= 10.1006/bbrc.2001.5413 }}
* {{cite journal | vauthors = Ihara M, Tomimoto H, Kitayama H, Morioka Y, Akiguchi I, Shibasaki H, Noda M, Kinoshita M | title = Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies | journal = The Journal of Biological Chemistry | volume = 278 | issue = 26 | pages = 24095–102 | date = June 2003 | pmid = 12695511 | doi = 10.1074/jbc.M301352200 }}
*{{cite journal | author=Tanaka M, Kijima H, Itoh J, ''et al.'' |title=Impaired expression of a human septin family gene Bradeion inhibits the growth and tumorigenesis of colorectal cancer in vitro and in vivo. |journal=Cancer Gene Ther. |volume=9 |issue= 6 |pages= 483-8 |year= 2002 |pmid= 12032658 |doi= 10.1038/sj.cgt.7700460 }}
* {{cite journal | vauthors = Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B | author14-link=Ted M. Dawson | author15-link=Benjamin Wolozin | title = SEPT5_v2 is a parkin-binding protein | journal = Brain Research. Molecular Brain Research | volume = 117 | issue = 2 | pages = 179–89 | date = October 2003 | pmid = 14559152 | doi = 10.1016/S0169-328X(03)00318-8 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Gottfried Y, Rotem A, Lotan R, Steller H, Larisch S | title = The mitochondrial ARTS protein promotes apoptosis through targeting XIAP | journal = The EMBO Journal | volume = 23 | issue = 7 | pages = 1627–35 | date = April 2004 | pmid = 15029247 | pmc = 391065 | doi = 10.1038/sj.emboj.7600155 }}
*{{cite journal | author=Vega IE, Hsu SC |title=The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells. |journal=Neuroreport |volume=14 |issue= 1 |pages= 31-7 |year= 2003 |pmid= 12544826 |doi= 10.1097/01.wnr.0000050304.92401.50 }}
* {{cite journal | vauthors = Bläser S, Horn J, Würmell P, Bauer H, Strümpell S, Nurden P, Pagenstecher A, Busse A, Wunderle D, Hainmann I, Zieger B | title = The novel human platelet septin SEPT8 is an interaction partner of SEPT4 | journal = Thrombosis and Haemostasis | volume = 91 | issue = 5 | pages = 959–66 | date = May 2004 | pmid = 15116257 | doi = 10.1160/TH03-09-0578 }}
*{{cite journal | author=Ihara M, Tomimoto H, Kitayama H, ''et al.'' |title=Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies. |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 24095-102 |year= 2003 |pmid= 12695511 |doi= 10.1074/jbc.M301352200 }}
* {{cite journal | vauthors = Elhasid R, Sahar D, Merling A, Zivony Y, Rotem A, Ben-Arush M, Izraeli S, Bercovich D, Larisch S | title = Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients | journal = Oncogene | volume = 23 | issue = 32 | pages = 5468–75 | date = July 2004 | pmid = 15122323 | doi = 10.1038/sj.onc.1207725 }}
*{{cite journal | author=Choi P, Snyder H, Petrucelli L, ''et al.'' |title=SEPT5_v2 is a parkin-binding protein. |journal=Brain Res. Mol. Brain Res. |volume=117 |issue= 2 |pages= 179-89 |year= 2004 |pmid= 14559152 |doi= }}
* {{cite journal | vauthors = Martínez C, Sanjuan MA, Dent JA, Karlsson L, Ware J | title = Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol | journal = The Biochemical Journal | volume = 382 | issue = Pt 3 | pages = 783–91 | date = September 2004 | pmid = 15214843 | pmc = 1133953 | doi = 10.1042/BJ20040372 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Lotan R, Rotem A, Gonen H, Finberg JP, Kemeny S, Steller H, Ciechanover A, Larisch S | title = Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation | journal = The Journal of Biological Chemistry | volume = 280 | issue = 27 | pages = 25802–10 | date = July 2005 | pmid = 15837787 | doi = 10.1074/jbc.M501955200 }}
*{{cite journal | author=Gottfried Y, Rotem A, Lotan R, ''et al.'' |title=The mitochondrial ARTS protein promotes apoptosis through targeting XIAP. |journal=EMBO J. |volume=23 |issue= 7 |pages= 1627-35 |year= 2005 |pmid= 15029247 |doi= 10.1038/sj.emboj.7600155 }}
* {{cite journal | vauthors = Lee JW, Soung YH, Young Kim S, Woo Nam S, Sang Park W, Young Lee J, Jin Yoo N, Lee SH | title = Mutational analysis of proapoptotic ARTS P-loop domain in common human cancers | journal = Pathology, Research and Practice | volume = 202 | issue = 2 | pages = 67–70 | year = 2006 | pmid = 16376484 | doi = 10.1016/j.prp.2005.11.001 }}
*{{cite journal | author=Bläser S, Horn J, Würmell P, ''et al.'' |title=The novel human platelet septin SEPT8 is an interaction partner of SEPT4. |journal=Thromb. Haemost. |volume=91 |issue= 5 |pages= 959-66 |year= 2004 |pmid= 15116257 |doi= 10.1267/THRO04050959 }}
* {{cite journal | vauthors = Lee JW, Soung YH, Kim SY, Nam SW, Park WS, Lee JY, Yoo NJ, Lee SH | title = Mutational analysis of P-loop domains of proapoptotic Nod1 and ARTS genes in colon carcinomas | journal = Acta Oncologica | volume = 45 | issue = 1 | pages = 101–2 | year = 2006 | pmid = 16464805 | doi = 10.1080/02841860500374497 }}
*{{cite journal | author=Elhasid R, Sahar D, Merling A, ''et al.'' |title=Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients. |journal=Oncogene |volume=23 |issue= 32 |pages= 5468-75 |year= 2004 |pmid= 15122323 |doi= 10.1038/sj.onc.1207725 }}
* {{cite journal | vauthors = Garcia W, de Araújo AP, Neto Mde O, Ballestero MR, Polikarpov I, Tanaka M, Tanaka T, Garratt RC | title = Dissection of a human septin: definition and characterization of distinct domains within human SEPT4 | journal = Biochemistry | volume = 45 | issue = 46 | pages = 13918–31 | date = November 2006 | pmid = 17105210 | doi = 10.1021/bi061549z }}
*{{cite journal | author=Martínez C, Sanjuan MA, Dent JA, ''et al.'' |title=Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol. |journal=Biochem. J. |volume=382 |issue= Pt 3 |pages= 783-91 |year= 2005 |pmid= 15214843 |doi= 10.1042/BJ20040372 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Lotan R, Rotem A, Gonen H, ''et al.'' |title=Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation. |journal=J. Biol. Chem. |volume=280 |issue= 27 |pages= 25802-10 |year= 2005 |pmid= 15837787 |doi= 10.1074/jbc.M501955200 }}
*{{cite journal  | author=Lee JW, Soung YH, Young Kim S, ''et al.'' |title=Mutational analysis of proapoptotic ARTS P-loop domain in common human cancers. |journal=Pathol. Res. Pract. |volume=202 |issue= 2 |pages= 67-70 |year= 2006 |pmid= 16376484 |doi= 10.1016/j.prp.2005.11.001 }}
*{{cite journal  | author=Lee JW, Soung YH, Kim SY, ''et al.'' |title=Mutational analysis of P-loop domains of proapoptotic Nod1 and ARTS genes in colon carcinomas. |journal=Acta oncologica (Stockholm, Sweden) |volume=45 |issue= 1 |pages= 101-2 |year= 2006 |pmid= 16464805 |doi= 10.1080/02841860500374497 }}
*{{cite journal  | author=Garcia W, de Araújo AP, Neto Mde O, ''et al.'' |title=Dissection of a human septin: definition and characterization of distinct domains within human SEPT4. |journal=Biochemistry |volume=45 |issue= 46 |pages= 13918-31 |year= 2007 |pmid= 17105210 |doi= 10.1021/bi061549z }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
 
{{WikiDoc Sources}}
{{gene-17-stub}}

Latest revision as of 17:36, 19 August 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Septin-4 is a protein that in humans is encoded by the SEPT4 gene.[1][2]

Function

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. The protein encoded by this gene is thought to be part of a complex involved in cytokinesis. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.[2]

References

  1. ↑ Paavola P, Horelli-Kuitunen N, Palotie A, Peltonen L (January 1999). "Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene". Genomics. 55 (1): 122–5. doi:10.1006/geno.1998.5612. PMID 9889007.
  2. ↑ 2.0 2.1 "Entrez Gene: SEPT4 septin 4".

Further reading

  • Xie H, Surka M, Howard J, Trimble WS (1999). "Characterization of the mammalian septin H5: distinct patterns of cytoskeletal and membrane association from other septin proteins". Cell Motility and the Cytoskeleton. 43 (1): 52–62. doi:10.1002/(SICI)1097-0169(1999)43:1<52::AID-CM6>3.0.CO;2-5. PMID 10340703.
  • Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, Gottfried Y, Birkey Reffey S, de Caestecker MP, Danielpour D, Book-Melamed N, Timberg R, Duckett CS, Lechleider RJ, Steller H, Orly J, Kim SJ, Roberts AB (December 2000). "A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif". Nature Cell Biology. 2 (12): 915–21. doi:10.1038/35046566. PMID 11146656.
  • Zieger B, Tran H, Hainmann I, Wunderle D, Zgaga-Griesz A, Blaser S, Ware J (December 2000). "Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2". Gene. 261 (2): 197–203. doi:10.1016/S0378-1119(00)00527-8. PMID 11167005.
  • Tanaka M, Tanaka T, Kijima H, Itoh J, Matsuda T, Hori S, Yamamoto M (August 2001). "Characterization of tissue- and cell-type-specific expression of a novel human septin family gene, Bradeion". Biochemical and Biophysical Research Communications. 286 (3): 547–53. doi:10.1006/bbrc.2001.5413. PMID 11511094.
  • Tanaka M, Kijima H, Itoh J, Matsuda T, Tanaka T (June 2002). "Impaired expression of a human septin family gene Bradeion inhibits the growth and tumorigenesis of colorectal cancer in vitro and in vivo". Cancer Gene Therapy. 9 (6): 483–8. doi:10.1038/sj.cgt.7700460. PMID 12032658.
  • Vega IE, Hsu SC (January 2003). "The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells". NeuroReport. 14 (1): 31–7. doi:10.1097/01.wnr.0000050304.92401.50. PMID 12544826.
  • Ihara M, Tomimoto H, Kitayama H, Morioka Y, Akiguchi I, Shibasaki H, Noda M, Kinoshita M (June 2003). "Association of the cytoskeletal GTP-binding protein Sept4/H5 with cytoplasmic inclusions found in Parkinson's disease and other synucleinopathies". The Journal of Biological Chemistry. 278 (26): 24095–102. doi:10.1074/jbc.M301352200. PMID 12695511.
  • Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B (October 2003). "SEPT5_v2 is a parkin-binding protein". Brain Research. Molecular Brain Research. 117 (2): 179–89. doi:10.1016/S0169-328X(03)00318-8. PMID 14559152.
  • Gottfried Y, Rotem A, Lotan R, Steller H, Larisch S (April 2004). "The mitochondrial ARTS protein promotes apoptosis through targeting XIAP". The EMBO Journal. 23 (7): 1627–35. doi:10.1038/sj.emboj.7600155. PMC 391065. PMID 15029247.
  • Bläser S, Horn J, Würmell P, Bauer H, Strümpell S, Nurden P, Pagenstecher A, Busse A, Wunderle D, Hainmann I, Zieger B (May 2004). "The novel human platelet septin SEPT8 is an interaction partner of SEPT4". Thrombosis and Haemostasis. 91 (5): 959–66. doi:10.1160/TH03-09-0578. PMID 15116257.
  • Elhasid R, Sahar D, Merling A, Zivony Y, Rotem A, Ben-Arush M, Izraeli S, Bercovich D, Larisch S (July 2004). "Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients". Oncogene. 23 (32): 5468–75. doi:10.1038/sj.onc.1207725. PMID 15122323.
  • Martínez C, Sanjuan MA, Dent JA, Karlsson L, Ware J (September 2004). "Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol". The Biochemical Journal. 382 (Pt 3): 783–91. doi:10.1042/BJ20040372. PMC 1133953. PMID 15214843.
  • Lotan R, Rotem A, Gonen H, Finberg JP, Kemeny S, Steller H, Ciechanover A, Larisch S (July 2005). "Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation". The Journal of Biological Chemistry. 280 (27): 25802–10. doi:10.1074/jbc.M501955200. PMID 15837787.
  • Lee JW, Soung YH, Young Kim S, Woo Nam S, Sang Park W, Young Lee J, Jin Yoo N, Lee SH (2006). "Mutational analysis of proapoptotic ARTS P-loop domain in common human cancers". Pathology, Research and Practice. 202 (2): 67–70. doi:10.1016/j.prp.2005.11.001. PMID 16376484.
  • Lee JW, Soung YH, Kim SY, Nam SW, Park WS, Lee JY, Yoo NJ, Lee SH (2006). "Mutational analysis of P-loop domains of proapoptotic Nod1 and ARTS genes in colon carcinomas". Acta Oncologica. 45 (1): 101–2. doi:10.1080/02841860500374497. PMID 16464805.
  • Garcia W, de Araújo AP, Neto Mde O, Ballestero MR, Polikarpov I, Tanaka M, Tanaka T, Garratt RC (November 2006). "Dissection of a human septin: definition and characterization of distinct domains within human SEPT4". Biochemistry. 45 (46): 13918–31. doi:10.1021/bi061549z. PMID 17105210.


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