SSBP1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Single-stranded DNA-binding protein, mitochondrial''' is a [[protein]] that in humans is encoded by the ''SSBP1'' [[gene]].<ref name="pmid7789991">{{cite journal | vauthors = Tiranti V, Rossi E, Ruiz-Carrillo A, Rossi G, Rocchi M, DiDonato S, Zuffardi O, Zeviani M | title = Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis | journal = Genomics | volume = 25 | issue = 2 | pages = 559–64 | date = January 1995 | pmid = 7789991 | pmc =  | doi = 10.1016/0888-7543(95)80058-T }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SSBP1 single-stranded DNA binding protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6742| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image = PBB_Protein_SSBP1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1s3o.
| PDB = {{PDB2|1s3o}}, {{PDB2|2dud}}, {{PDB2|3ull}}
| Name = Single-stranded DNA binding protein 1
| HGNCid = 11317
| Symbol = SSBP1
| AltSymbols =; SSBP
| OMIM = 600439
| ECnumber = 
| Homologene = 74462
| MGIid = 1920040
| GeneAtlas_image1 = PBB_GE_SSBP1_202591_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003697 |text = single-stranded DNA binding}}
| Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}}
| Process = {{GNF_GO|id=GO:0006260 |text = DNA replication}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6742
    | Hs_Ensembl = ENSG00000106028
    | Hs_RefseqProtein = NP_003134
    | Hs_RefseqmRNA = NM_003143
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 141084628
    | Hs_GenLoc_end = 141096725
    | Hs_Uniprot = Q04837
    | Mm_EntrezGene = 381760
    | Mm_Ensembl = ENSMUSG00000029911
    | Mm_RefseqmRNA = NM_028358
    | Mm_RefseqProtein = NP_082634
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 40401022
    | Mm_GenLoc_end = 40408194
    | Mm_Uniprot = Q8R2K3
  }}
}}
'''Single-stranded DNA binding protein 1''', also known as '''SSBP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SSBP1 single-stranded DNA binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6742| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
SSBP 1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995).[supplied by OMIM]<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = SSBP is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: SSBP1 single-stranded DNA binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6742| accessdate = }}</ref>
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Tiranti V, Rocchi M, DiDonato S, Zeviani M | title = Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB) | journal = Gene | volume = 126 | issue = 2 | pages = 219–25 | date = April 1993 | pmid = 8482537 | doi = 10.1016/0378-1119(93)90370-I }}
| citations =
* {{cite journal | vauthors = Yang C, Curth U, Urbanke C, Kang C | title = Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution | journal = Nature Structural Biology | volume = 4 | issue = 2 | pages = 153–7 | date = February 1997 | pmid = 9033597 | doi = 10.1038/nsb0297-153 }}
*{{cite journal  | author=Tiranti V, Rossi E, Ruiz-Carrillo A, ''et al.'' |title=Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis. |journal=Genomics |volume=25 |issue= 2 |pages= 559-64 |year= 1995 |pmid= 7789991 |doi=  }}
* {{cite journal | vauthors = Schultz RA, Swoap SJ, McDaniel LD, Zhang B, Koon EC, Garry DJ, Li K, Williams RS | title = Differential expression of mitochondrial DNA replication factors in mammalian tissues | journal = The Journal of Biological Chemistry | volume = 273 | issue = 6 | pages = 3447–51 | date = February 1998 | pmid = 9452467 | doi = 10.1074/jbc.273.6.3447 }}
*{{cite journal | author=Tiranti V, Rocchi M, DiDonato S, Zeviani M |title=Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB). |journal=Gene |volume=126 |issue= 2 |pages= 219-25 |year= 1993 |pmid= 8482537 |doi= }}
* {{cite journal | vauthors = Spelbrink JN, Toivonen JM, Hakkaart GA, Kurkela JM, Cooper HM, Lehtinen SK, Lecrenier N, Back JW, Speijer D, Foury F, Jacobs HT | title = In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells | journal = The Journal of Biological Chemistry | volume = 275 | issue = 32 | pages = 24818–28 | date = August 2000 | pmid = 10827171 | doi = 10.1074/jbc.M000559200 }}
*{{cite journal | author=Yang C, Curth U, Urbanke C, Kang C |title=Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution. |journal=Nat. Struct. Biol. |volume=4 |issue= 2 |pages= 153-7 |year= 1997 |pmid= 9033597 |doi= }}
* {{cite journal | vauthors = Müller-Höcker J, Schäfer S, Li K | title = Immunocytochemical localization of mitochondrial single-stranded DNA-binding protein in mitochondria-rich cells of normal and neoplastic human tissue | journal = Applied Immunohistochemistry & Molecular Morphology | volume = 9 | issue = 3 | pages = 276–80 | date = September 2001 | pmid = 11556757 | doi = 10.1097/00022744-200109000-00013 }}
*{{cite journal | author=Schultz RA, Swoap SJ, McDaniel LD, ''et al.'' |title=Differential expression of mitochondrial DNA replication factors in mammalian tissues. |journal=J. Biol. Chem. |volume=273 |issue= 6 |pages= 3447-51 |year= 1998 |pmid= 9452467 |doi= }}
* {{cite journal | vauthors = Takamatsu C, Umeda S, Ohsato T, Ohno T, Abe Y, Fukuoh A, Shinagawa H, Hamasaki N, Kang D | title = Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein | journal = EMBO Reports | volume = 3 | issue = 5 | pages = 451–6 | date = May 2002 | pmid = 11964388 | pmc = 1084112 | doi = 10.1093/embo-reports/kvf099 }}
*{{cite journal | author=Spelbrink JN, Toivonen JM, Hakkaart GA, ''et al.'' |title=In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells. |journal=J. Biol. Chem. |volume=275 |issue= 32 |pages= 24818-28 |year= 2000 |pmid= 10827171 |doi= 10.1074/jbc.M000559200 }}
* {{cite journal | vauthors = Chen L, Segal D, Hukriede NA, Podtelejnikov AV, Bayarsaihan D, Kennison JA, Ogryzko VV, Dawid IB, Westphal H | title = Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 99 | issue = 22 | pages = 14320–5 | date = October 2002 | pmid = 12381786 | pmc = 137882 | doi = 10.1073/pnas.212532399 }}
*{{cite journal | author=Müller-Höcker J, Schäfer S, Li K |title=Immunocytochemical localization of mitochondrial single-stranded DNA-binding protein in mitochondria-rich cells of normal and neoplastic human tissue. |journal=Appl. Immunohistochem. Mol. Morphol. |volume=9 |issue= 3 |pages= 276-80 |year= 2002 |pmid= 11556757 |doi= }}
* {{cite journal | vauthors = Diez-Tascón C, Dodds KG, Crawford AM | title = Linkage mapping of the ovine single-stranded DNA-binding protein 1 (SSBP1) using microsatellite marker OARCDT7 | journal = Animal Genetics | volume = 33 | issue = 6 | pages = 468 | date = December 2002 | pmid = 12464025 | doi = 10.1046/j.1365-2052.2002.00938_1.x }}
*{{cite journal | author=Takamatsu C, Umeda S, Ohsato T, ''et al.'' |title=Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein. |journal=EMBO Rep. |volume=3 |issue= 5 |pages= 451-6 |year= 2002 |pmid= 11964388 |doi= 10.1093/embo-reports/kvf099 }}
* {{cite journal | vauthors = Bayarsaihan D | title = SSDP1 gene encodes a protein with a conserved N-terminal FORWARD domain | journal = Biochimica et Biophysica Acta | volume = 1599 | issue = 1-2 | pages = 152–5 | date = September 2002 | pmid = 12479417 | doi = 10.1016/s1570-9639(02)00376-x }}
*{{cite journal | author=Chen L, Segal D, Hukriede NA, ''et al.'' |title=Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 22 |pages= 14320-5 |year= 2002 |pmid= 12381786 |doi= 10.1073/pnas.212532399 }}
* {{cite journal | vauthors = Pocernich CB, Poon HF, Boyd-Kimball D, Lynn BC, Nath A, Klein JB, Butterfield DA | title = Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat | journal = Brain Research. Molecular Brain Research | volume = 133 | issue = 2 | pages = 299–306 | date = February 2005 | pmid = 15710247 | doi = 10.1016/j.molbrainres.2004.10.024 }}
*{{cite journal | author=Diez-Tascón C, Dodds KG, Crawford AM |title=Linkage mapping of the ovine single-stranded DNA-binding protein 1 (SSBP1) using microsatellite marker OARCDT7. |journal=Anim. Genet. |volume=33 |issue= 6 |pages= 468 |year= 2003 |pmid= 12464025 |doi= }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Bayarsaihan D |title=SSDP1 gene encodes a protein with a conserved N-terminal FORWARD domain. |journal=Biochim. Biophys. Acta |volume=1599 |issue= 1-2 |pages= 152-5 |year= 2003 |pmid= 12479417 |doi=  }}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Pocernich CB, Poon HF, Boyd-Kimball D, ''et al.'' |title=Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat. |journal=Brain Res. Mol. Brain Res. |volume=133 |issue= 2 |pages= 299-306 |year= 2005 |pmid= 15710247 |doi= 10.1016/j.molbrainres.2004.10.024 }}
}}
{{refend}}
{{refend}}


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{{PDB Gallery|geneid=6742}}
{{WikiDoc Sources}}
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Latest revision as of 07:05, 11 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Single-stranded DNA-binding protein, mitochondrial is a protein that in humans is encoded by the SSBP1 gene.[1][2]

Function

SSBP 1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995).[supplied by OMIM][2]

References

  1. Tiranti V, Rossi E, Ruiz-Carrillo A, Rossi G, Rocchi M, DiDonato S, Zuffardi O, Zeviani M (January 1995). "Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis". Genomics. 25 (2): 559–64. doi:10.1016/0888-7543(95)80058-T. PMID 7789991.
  2. 2.0 2.1 "Entrez Gene: SSBP1 single-stranded DNA binding protein 1".

Further reading