TFE3: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Transcription factor E3''' is a [[protein]] that in humans is encoded by the ''TFE3'' [[gene]].<ref name="pmid1672758">{{cite journal | vauthors = Puck JM, Stewart CC, Henthorn PS | title = A high-frequency RFLP at the human TFE3 locus on the X chromosome | journal = Nucleic Acids Res | volume = 19 | issue = 3 | pages = 684 | date = May 1991 | pmid = 1672758 | pmc = 333678 | doi = 10.1093/nar/19.3.684-a }}</ref><ref name="pmid1685140">{{cite journal | vauthors = Henthorn PS, Stewart CC, Kadesch T, Puck JM | title = The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22 | journal = Genomics | volume = 11 | issue = 2 | pages = 374–8 | date = Feb 1992 | pmid = 1685140 | pmc =  | doi = 10.1016/0888-7543(91)90145-5 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TFE3 transcription factor binding to IGHM enhancer 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7030| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Transcription factor binding to IGHM enhancer 3
| HGNCid = 11752
| Symbol = TFE3
| AltSymbols =; RCCP2; TFEA
| OMIM = 314310
| ECnumber = 
| Homologene = 4755
| MGIid = 98511
| GeneAtlas_image1 = PBB_GE_TFE3_206649_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_TFE3_212457_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0045670 |text = regulation of osteoclast differentiation}} {{GNF_GO|id=GO:0045893 |text = positive regulation of transcription, DNA-dependent}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7030
    | Hs_Ensembl = ENSG00000068323
    | Hs_RefseqProtein = NP_006512
    | Hs_RefseqmRNA = NM_006521
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 48771186
    | Hs_GenLoc_end = 48787956
    | Hs_Uniprot = P19532
    | Mm_EntrezGene = 209446
    | Mm_Ensembl = ENSMUSG00000000134
    | Mm_RefseqmRNA = NM_172472
    | Mm_RefseqProtein = NP_766060
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 6919632
    | Mm_GenLoc_end = 6932160
    | Mm_Uniprot = Q05BT8
  }}
}}
'''Transcription factor binding to IGHM enhancer 3''', also known as '''TFE3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TFE3 transcription factor binding to IGHM enhancer 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7030| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
TFE3, a member of the helix-loop-helix family of [[transcription factor]]s, binds to the mu-E3 motif of the [[immunoglobulin]] heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991).[supplied by OMIM]<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: TFE3 transcription factor binding to IGHM enhancer 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7030| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
TFE3 has been shown to [[Protein-protein interaction|interact]] with:
* [[E2F3]],<ref name = pmid12748276>{{cite journal | vauthors = Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR | title = Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor | journal = Mol. Cell. Biol. | volume = 23 | issue = 11 | pages = 3707–20 | date = Jun 2003 | pmid = 12748276 | pmc = 155231 | doi =  10.1128/mcb.23.11.3707-3720.2003}}</ref>
* [[Microphthalmia-associated transcription factor]],<ref name = pmid11930005>{{cite journal | vauthors = Steingrimsson E, Tessarollo L, Pathak B, Hou L, Arnheiter H, Copeland NG, Jenkins NA | title = Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 7 | pages = 4477–82 | date = Apr 2002 | pmid = 11930005 | pmc = 123673 | doi = 10.1073/pnas.072071099 }}</ref><ref name = pmid11818452>{{cite journal | vauthors = Mansky KC, Sulzbacher S, Purdom G, Nelsen L, Hume DA, Rehli M, Ostrowski MC | title = The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter | journal = J. Leukoc. Biol. | volume = 71 | issue = 2 | pages = 304–10 | date = Feb 2002 | pmid = 11818452 | doi =  }}</ref> and
* [[Mothers against decapentaplegic homolog 3]]<ref name = pmid12551947>{{cite journal | vauthors = Grinberg AV, Kerppola T | title = Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activity | journal = J. Biol. Chem. | volume = 278 | issue = 13 | pages = 11227–36 | date = Mar 2003 | pmid = 12551947 | doi = 10.1074/jbc.M211734200 }}</ref><ref name = pmid10557285>{{cite journal | vauthors = Hua X, Miller ZA, Wu G, Shi Y, Lodish HF | title = Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 96 | issue = 23 | pages = 13130–5 | date = Nov 1999 | pmid = 10557285 | pmc = 23912 | doi =  10.1073/pnas.96.23.13130}}</ref>
 
==Translocations==
A proportion of renal carcinomas  (RCC) that occur in young patients are associated with translocations involving the TFE3 gene at chromosome Xp11.2 [[PRCC (gene)|PRCC]]
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Beckmann H, Kadesch T | title = The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity | journal = Genes Dev. | volume = 5 | issue = 6 | pages = 1057–66 | year = 1991 | pmid = 2044953 | doi = 10.1101/gad.5.6.1057 }}
| citations =
* {{cite journal | vauthors = Beckmann H, Su LK, Kadesch T | title = TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif | journal = Genes Dev. | volume = 4 | issue = 2 | pages = 167–79 | year = 1990 | pmid = 2338243 | doi = 10.1101/gad.4.2.167 }}
*{{cite journal | author=Puck JM, Stewart CC, Henthorn PS |title=A high-frequency RFLP at the human TFE3 locus on the X chromosome. |journal=Nucleic Acids Res. |volume=19 |issue= 3 |pages= 684 |year= 1991 |pmid= 1672758 |doi= }}
* {{cite journal | vauthors = Zhao GQ, Zhao Q, Zhou X, Mattei MG, de Crombrugghe B | title = TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation | journal = Mol. Cell. Biol. | volume = 13 | issue = 8 | pages = 4505–12 | year = 1993 | pmid = 8336698 | pmc = 360062 | doi =  }}
*{{cite journal | author=Henthorn PS, Stewart CC, Kadesch T, Puck JM |title=The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22. |journal=Genomics |volume=11 |issue= 2 |pages= 374-8 |year= 1992 |pmid= 1685140 |doi= }}
* {{cite journal | vauthors = Sidhar SK, Clark J, Gill S, Hamoudi R, Crew AJ, Gwilliam R, Ross M, Linehan WM, Birdsall S, Shipley J, Cooper CS | title = The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene | journal = Hum. Mol. Genet. | volume = 5 | issue = 9 | pages = 1333–8 | year = 1997 | pmid = 8872474 | doi = 10.1093/hmg/5.9.1333 }}
*{{cite journal | author=Beckmann H, Kadesch T |title=The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity. |journal=Genes Dev. |volume=5 |issue= 6 |pages= 1057-66 |year= 1991 |pmid= 2044953 |doi=  }}
* {{cite journal | vauthors = Weterman MA, Wilbrink M, Geurts van Kessel A | title = Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 93 | issue = 26 | pages = 15294–8 | year = 1997 | pmid = 8986805 | pmc = 26398 | doi = 10.1073/pnas.93.26.15294 }}
*{{cite journal | author=Beckmann H, Su LK, Kadesch T |title=TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. |journal=Genes Dev. |volume=4 |issue= 2 |pages= 167-79 |year= 1990 |pmid= 2338243 |doi= }}
* {{cite journal | vauthors = Clark J, Lu YJ, Sidhar SK, Parker C, Gill S, Smedley D, Hamoudi R, Linehan WM, Shipley J, Cooper CS | title = Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma | journal = Oncogene | volume = 15 | issue = 18 | pages = 2233–9 | year = 1997 | pmid = 9393982 | doi = 10.1038/sj.onc.1201394 }}
*{{cite journal | author=Zhao GQ, Zhao Q, Zhou X, ''et al.'' |title=TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. |journal=Mol. Cell. Biol. |volume=13 |issue= 8 |pages= 4505-12 |year= 1993 |pmid= 8336698 |doi= }}
* {{cite journal | vauthors = Hua X, Liu X, Ansari DO, Lodish HF | title = Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene | journal = Genes Dev. | volume = 12 | issue = 19 | pages = 3084–95 | year = 1998 | pmid = 9765209 | pmc = 317197 | doi = 10.1101/gad.12.19.3084 }}
*{{cite journal | author=Sidhar SK, Clark J, Gill S, ''et al.'' |title=The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene. |journal=Hum. Mol. Genet. |volume=5 |issue= 9 |pages= 1333-8 |year= 1997 |pmid= 8872474 |doi= }}
* {{cite journal | vauthors = Steingrímsson E, Tessarollo L, Reid SW, Jenkins NA, Copeland NG | title = The bHLH-Zip transcription factor Tfeb is essential for placental vascularization | journal = Development | volume = 125 | issue = 23 | pages = 4607–16 | year = 1999 | pmid = 9806910 | doi = }}
*{{cite journal | author=Weterman MA, Wilbrink M, Geurts van Kessel A |title=Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 26 |pages= 15294-8 |year= 1997 |pmid= 8986805 |doi= }}
* {{cite journal | vauthors = Hua X, Miller ZA, Wu G, Shi Y, Lodish HF | title = Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 96 | issue = 23 | pages = 13130–5 | year = 1999 | pmid = 10557285 | pmc = 23912 | doi = 10.1073/pnas.96.23.13130 }}
*{{cite journal | author=Clark J, Lu YJ, Sidhar SK, ''et al.'' |title=Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma. |journal=Oncogene |volume=15 |issue= 18 |pages= 2233-9 |year= 1997 |pmid= 9393982 |doi= 10.1038/sj.onc.1201394 }}
* {{cite journal | vauthors = Weterman MJ, van Groningen JJ, Jansen A, van Kessel AG | title = Nuclear localization and transactivating capacities of the papillary renal cell carcinoma-associated TFE3 and PRCC (fusion) proteins | journal = Oncogene | volume = 19 | issue = 1 | pages = 69–74 | year = 2000 | pmid = 10644981 | doi = 10.1038/sj.onc.1203255 }}
*{{cite journal | author=Hua X, Liu X, Ansari DO, Lodish HF |title=Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. |journal=Genes Dev. |volume=12 |issue= 19 |pages= 3084-95 |year= 1998 |pmid= 9765209 |doi= }}
* {{cite journal | vauthors = Hua X, Miller ZA, Benchabane H, Wrana JL, Lodish HF | title = Synergism between transcription factors TFE3 and Smad3 in transforming growth factor-beta-induced transcription of the Smad7 gene | journal = J. Biol. Chem. | volume = 275 | issue = 43 | pages = 33205–8 | year = 2000 | pmid = 10973944 | doi = 10.1074/jbc.C000568200 }}
*{{cite journal | author=Steingrímsson E, Tessarollo L, Reid SW, ''et al.'' |title=The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. |journal=Development |volume=125 |issue= 23 |pages= 4607-16 |year= 1999 |pmid= 9806910 |doi= }}
* {{cite journal | vauthors = Ladanyi M, Lui MY, Antonescu CR, Krause-Boehm A, Meindl A, Argani P, Healey JH, Ueda T, Yoshikawa H, Meloni-Ehrig A, Sorensen PH, Mertens F, Mandahl N, van den Berghe H, Sciot R, Dal Cin P, Bridge J | title = The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25 | journal = Oncogene | volume = 20 | issue = 1 | pages = 48–57 | year = 2001 | pmid = 11244503 | doi = 10.1038/sj.onc.1204074 }}
*{{cite journal | author=Hua X, Miller ZA, Wu G, ''et al.'' |title=Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 23 |pages= 13130-5 |year= 1999 |pmid= 10557285 |doi= }}
* {{cite journal | vauthors = Weterman MA, van Groningen JJ, den Hartog A, Geurts van Kessel A | title = Transformation capacities of the papillary renal cell carcinoma-associated PRCCTFE3 and TFE3PRCC fusion genes | journal = Oncogene | volume = 20 | issue = 12 | pages = 1414–24 | year = 2001 | pmid = 11313885 | doi = 10.1038/sj.onc.1204213 }}
*{{cite journal | author=Weterman MJ, van Groningen JJ, Jansen A, van Kessel AG |title=Nuclear localization and transactivating capacities of the papillary renal cell carcinoma-associated TFE3 and PRCC (fusion) proteins. |journal=Oncogene |volume=19 |issue= 1 |pages= 69-74 |year= 2000 |pmid= 10644981 |doi= 10.1038/sj.onc.1203255 }}
* {{cite journal | vauthors = Heimann P, El Housni H, Ogur G, Weterman MA, Petty EM, Vassart G | title = Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas | journal = Cancer Res. | volume = 61 | issue = 10 | pages = 4130–5 | year = 2001 | pmid = 11358836 | doi = }}
*{{cite journal | author=Hua X, Miller ZA, Benchabane H, ''et al.'' |title=Synergism between transcription factors TFE3 and Smad3 in transforming growth factor-beta-induced transcription of the Smad7 gene. |journal=J. Biol. Chem. |volume=275 |issue= 43 |pages= 33205-8 |year= 2000 |pmid= 10973944 |doi= 10.1074/jbc.C000568200 }}
* {{cite journal | vauthors = Chung MC, Kim HK, Kawamoto S | title = TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells | journal = Biochemistry | volume = 40 | issue = 30 | pages = 8887–97 | year = 2001 | pmid = 11467950 | doi = 10.1021/bi002847d }}
*{{cite journal | author=Ladanyi M, Lui MY, Antonescu CR, ''et al.'' |title=The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25. |journal=Oncogene |volume=20 |issue= 1 |pages= 48-57 |year= 2001 |pmid= 11244503 |doi= 10.1038/sj.onc.1204074 }}
* {{cite journal | vauthors = Dintilhac A, Bernués J | title = HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences | journal = J. Biol. Chem. | volume = 277 | issue = 9 | pages = 7021–8 | year = 2002 | pmid = 11748221 | doi = 10.1074/jbc.M108417200 }}
*{{cite journal | author=Weterman MA, van Groningen JJ, den Hartog A, Geurts van Kessel A |title=Transformation capacities of the papillary renal cell carcinoma-associated PRCCTFE3 and TFE3PRCC fusion genes. |journal=Oncogene |volume=20 |issue= 12 |pages= 1414-24 |year= 2001 |pmid= 11313885 |doi= 10.1038/sj.onc.1204213 }}
* {{cite journal | vauthors = Kawata Y, Suzuki H, Higaki Y, Denisenko O, Schullery D, Abrass C, Bomsztyk K | title = bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteins | journal = J. Biol. Chem. | volume = 277 | issue = 13 | pages = 11375–84 | year = 2002 | pmid = 11801598 | doi = 10.1074/jbc.M111284200 }}
*{{cite journal | author=Heimann P, El Housni H, Ogur G, ''et al.'' |title=Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas. |journal=Cancer Res. |volume=61 |issue= 10 |pages= 4130-5 |year= 2001 |pmid= 11358836 |doi= }}
* {{cite journal | vauthors = Steingrimsson E, Tessarollo L, Pathak B, Hou L, Arnheiter H, Copeland NG, Jenkins NA | title = Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 7 | pages = 4477–82 | year = 2002 | pmid = 11930005 | pmc = 123673 | doi = 10.1073/pnas.072071099 }}
*{{cite journal | author=Chung MC, Kim HK, Kawamoto S |title=TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells. |journal=Biochemistry |volume=40 |issue= 30 |pages= 8887-97 |year= 2001 |pmid= 11467950 |doi= }}
*{{cite journal | author=Dintilhac A, Bernués J |title=HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7021-8 |year= 2002 |pmid= 11748221 |doi= 10.1074/jbc.M108417200 }}
*{{cite journal  | author=Kawata Y, Suzuki H, Higaki Y, ''et al.'' |title=bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteins. |journal=J. Biol. Chem. |volume=277 |issue= 13 |pages= 11375-84 |year= 2002 |pmid= 11801598 |doi= 10.1074/jbc.M111284200 }}
*{{cite journal  | author=Steingrimsson E, Tessarollo L, Pathak B, ''et al.'' |title=Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4477-82 |year= 2002 |pmid= 11930005 |doi= 10.1073/pnas.072071099 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 11:47, 15 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene.[1][2][3]

Function

TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991).[supplied by OMIM][3]

Interactions

TFE3 has been shown to interact with:

Translocations

A proportion of renal carcinomas (RCC) that occur in young patients are associated with translocations involving the TFE3 gene at chromosome Xp11.2 PRCC

References

  1. ↑ Puck JM, Stewart CC, Henthorn PS (May 1991). "A high-frequency RFLP at the human TFE3 locus on the X chromosome". Nucleic Acids Res. 19 (3): 684. doi:10.1093/nar/19.3.684-a. PMC 333678. PMID 1672758.
  2. ↑ Henthorn PS, Stewart CC, Kadesch T, Puck JM (Feb 1992). "The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22". Genomics. 11 (2): 374–8. doi:10.1016/0888-7543(91)90145-5. PMID 1685140.
  3. ↑ 3.0 3.1 "Entrez Gene: TFE3 transcription factor binding to IGHM enhancer 3".
  4. ↑ Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR (Jun 2003). "Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor". Mol. Cell. Biol. 23 (11): 3707–20. doi:10.1128/mcb.23.11.3707-3720.2003. PMC 155231. PMID 12748276.
  5. ↑ Steingrimsson E, Tessarollo L, Pathak B, Hou L, Arnheiter H, Copeland NG, Jenkins NA (Apr 2002). "Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development". Proc. Natl. Acad. Sci. U.S.A. 99 (7): 4477–82. doi:10.1073/pnas.072071099. PMC 123673. PMID 11930005.
  6. ↑ Mansky KC, Sulzbacher S, Purdom G, Nelsen L, Hume DA, Rehli M, Ostrowski MC (Feb 2002). "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter". J. Leukoc. Biol. 71 (2): 304–10. PMID 11818452.
  7. ↑ Grinberg AV, Kerppola T (Mar 2003). "Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activity". J. Biol. Chem. 278 (13): 11227–36. doi:10.1074/jbc.M211734200. PMID 12551947.
  8. ↑ Hua X, Miller ZA, Wu G, Shi Y, Lodish HF (Nov 1999). "Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins". Proc. Natl. Acad. Sci. U.S.A. 96 (23): 13130–5. doi:10.1073/pnas.96.23.13130. PMC 23912. PMID 10557285.

Further reading


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