TINAGL1: Difference between revisions

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{{Infobox_gene}}
{{GNF_Protein_box
'''Tubulointerstitial nephritis antigen-like''' is a [[protein]] that in humans is encoded by the ''TINAGL1'' [[gene]].<ref name="pmid11170462">{{cite journal | vauthors = Wex T, Lipyansky A, Bromme NC, Wex H, Guan XQ, Bromme D | title = TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells | journal = Biochemistry | volume = 40 | issue = 5 | pages = 1350–7 |date=Feb 2001 | pmid = 11170462 | pmc =  | doi =10.1021/bi002266o }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TINAGL1 tubulointerstitial nephritis antigen-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64129| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = Tubulointerstitial nephritis antigen-like 1
| HGNCid = 19168
| Symbol = TINAGL1
| AltSymbols =; ARG1; LCN7; LIECG3; TINAGRP
| OMIM = 
| ECnumber = 
| Homologene = 41472
| MGIid = 2137617
| GeneAtlas_image1 = PBB_GE_TINAGL1_219058_x_at_tn.png
| Function = {{GNF_GO|id=GO:0004197 |text = cysteine-type endopeptidase activity}} {{GNF_GO|id=GO:0005201 |text = extracellular matrix structural constituent}}
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}}
| Process = {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0016197 |text = endosome transport}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 64129
    | Hs_Ensembl = ENSG00000142910
    | Hs_RefseqProtein = NP_071447
    | Hs_RefseqmRNA = NM_022164
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 31814700
    | Hs_GenLoc_end = 31825874
    | Hs_Uniprot = Q9GZM7
    | Mm_EntrezGene = 94242
    | Mm_Ensembl = ENSMUSG00000028776
    | Mm_RefseqmRNA = NM_023476
    | Mm_RefseqProtein = NP_075965
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 129666758
    | Mm_GenLoc_end = 129677426
    | Mm_Uniprot = Q4FJX7
  }}
}}
'''Tubulointerstitial nephritis antigen-like 1''', also known as '''TINAGL1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TINAGL1 tubulointerstitial nephritis antigen-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64129| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Brömme NC, Wex T, Wex H, ''et al.'' |title=Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein. |journal=Biochem. Biophys. Res. Commun. |volume=271 |issue= 2 |pages= 474-80 |year= 2000 |pmid= 10799322 |doi= 10.1006/bbrc.2000.2639 }}
*{{cite journal   |vauthors=Brömme NC, Wex T, Wex H, etal |title=Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein. |journal=Biochem. Biophys. Res. Commun. |volume=271 |issue= 2 |pages= 474–80 |year= 2000 |pmid= 10799322 |doi= 10.1006/bbrc.2000.2639 }}
*{{cite journal  | author=Wex T, Lipyansky A, Brömme NC, ''et al.'' |title=TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells. |journal=Biochemistry |volume=40 |issue= 5 |pages= 1350-7 |year= 2001 |pmid= 11170462 |doi=  }}
*{{cite journal  | vauthors=Jiang LQ, Wen SJ, Wang HY, Chen LY |title=Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system. |journal=Hypertens. Res. |volume=25 |issue= 4 |pages= 647–52 |year= 2003 |pmid= 12358155 |doi=10.1291/hypres.25.647 }}
*{{cite journal  | author=Jiang LQ, Wen SJ, Wang HY, Chen LY |title=Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system. |journal=Hypertens. Res. |volume=25 |issue= 4 |pages= 647-52 |year= 2003 |pmid= 12358155 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148 }}
*{{cite journal | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal  | vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 | pmc=2286551 }}
*{{cite journal  | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819-24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Wan D, Gong Y, Qin W, etal |title=Large-scale cDNA transfection screening for genes related to cancer development and progression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724–9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101 | pmc=524842 }}
*{{cite journal | author=Wan D, Gong Y, Qin W, ''et al.'' |title=Large-scale cDNA transfection screening for genes related to cancer development and progression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724-9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal  |vauthors=Umeyama H, Iwadate M, Taguchi YH,  |title=TINAGL1 and B3GALNT1 are potential therapy target genes to suppress metastasis in non-small cell lung cancer. |journal=BMC Genomics  |volume=15 |issue= Suppl 9 |pages= S2 |year= 2014 |pmid= 25521548 |doi= 10.1186/1471-2164-15-S9-S2 |pmc=4290609}}
}}
*{{cite journal |vauthors=Bosse K, Haneder S, Arlt C, Ihling CH, Seufferlein T, Sinz A, |title=Mass spectrometry-based secretome analysis of non-small cell lung cancer cell lines. |journal=Proteomics |volume=16 |issue=21 |pages=2801–2814 |year=2016 |pmid=27569058 |doi=10.1002/pmic.201600297
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 22:38, 26 March 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Tubulointerstitial nephritis antigen-like is a protein that in humans is encoded by the TINAGL1 gene.[1][2]


References

  1. Wex T, Lipyansky A, Bromme NC, Wex H, Guan XQ, Bromme D (Feb 2001). "TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells". Biochemistry. 40 (5): 1350–7. doi:10.1021/bi002266o. PMID 11170462.
  2. "Entrez Gene: TINAGL1 tubulointerstitial nephritis antigen-like 1".

Further reading