TNP2: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
WikiBot (talk | contribs)
Bots, Bureaucrats, bureaucrats, interwiki, nocaptcha, Administrators
57,550 edits
m Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +)
 
Matt Pijoan (talk | contribs)
Bots, Bureaucrats, bureaucrats, Interface administrators, interwiki, nocaptcha, smwadministrator, staff, Administrators, Widget editors
7,579 edits
m 1 revision imported
 
(2 intermediate revisions by 2 users not shown)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Nuclear transition protein 2''' is a [[protein]] that in humans is encoded by the ''TNP2'' [[gene]].<ref name="pmid1395729">{{cite journal |vauthors=Engel W, Keime S, Kremling H, Hameister H, Schluter G | title = The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome | journal = Cytogenet Cell Genet | volume = 61 | issue = 2 | pages = 158–9 |date=Nov 1992 | pmid = 1395729 | pmc =  | doi =10.1159/000133397 }}</ref><ref name="pmid2250010">{{cite journal |vauthors=Baskaran R, Rao MR | title = Interaction of spermatid-specific protein TP2 with nucleic acids, in vitro. A comparative study with TP1 | journal = J Biol Chem | volume = 265 | issue = 34 | pages = 21039–47 |date=Jan 1991 | pmid = 2250010 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TNP2 transition protein 2 (during histone to protamine replacement)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7142| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Transition protein 2 (during histone to protamine replacement)
| HGNCid = 11952
| Symbol = TNP2
| AltSymbols =; MGC116783; MGC116785
| OMIM = 190232
| ECnumber = 
| Homologene = 3958
| MGIid = 98785
| GeneAtlas_image1 = PBB_GE_TNP2_207736_s_at_tn.png
  | GeneAtlas_image2 = PBB_GE_TNP2_217460_at_tn.png
  | Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0000786 |text = nucleosome}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005694 |text = chromosome}}
| Process = {{GNF_GO|id=GO:0006323 |text = DNA packaging}} {{GNF_GO|id=GO:0007001 |text = chromosome organization and biogenesis (sensu Eukaryota)}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007283 |text = spermatogenesis}} {{GNF_GO|id=GO:0007340 |text = acrosome reaction}} {{GNF_GO|id=GO:0007341 |text = penetration of zona pellucida}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7142
    | Hs_Ensembl = ENSG00000178279
    | Hs_RefseqProtein = NP_005416
    | Hs_RefseqmRNA = NM_005425
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 11270219
    | Hs_GenLoc_end = 11270620
    | Hs_Uniprot = Q05952
    | Mm_EntrezGene = 21959
    | Mm_Ensembl = ENSMUSG00000043050
    | Mm_RefseqmRNA = NM_013694
    | Mm_RefseqProtein = NP_038722
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 16
    | Mm_GenLoc_start = 10701514
    | Mm_GenLoc_end = 10702238
    | Mm_Uniprot = Q91XK4
  }}
}}
'''Transition protein 2 (during histone to protamine replacement)''', also known as '''TNP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TNP2 transition protein 2 (during histone to protamine replacement)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7142| accessdate = }}</ref>
 
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
{{PBB_Summary
Line 54: Line 6:
| summary_text =  
| summary_text =  
}}
}}
==References==
{{reflist}}


==References==
{{reflist|2}}
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Schlüter G, Kremling H, Engel W |title=The gene for human transition protein 2: nucleotide sequence, assignment to the protamine gene cluster, and evidence for its low expression. |journal=Genomics |volume=14 |issue= 2 |pages= 377-83 |year= 1992 |pmid= 1385303 |doi= }}
*{{cite journal  |vauthors=Schlüter G, Kremling H, Engel W |title=The gene for human transition protein 2: nucleotide sequence, assignment to the protamine gene cluster, and evidence for its low expression. |journal=Genomics |volume=14 |issue= 2 |pages= 377–83 |year= 1992 |pmid= 1385303 |doi=10.1016/S0888-7543(05)80229-0 }}
*{{cite journal  | author=Engel W, Keime S, Kremling H, ''et al.'' |title=The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome. |journal=Cytogenet. Cell Genet. |volume=61 |issue= 2 |pages= 158-9 |year= 1992 |pmid= 1395729 |doi= }}
*{{cite journal  |vauthors=Kundu TK, Rao MR |title=DNA condensation by the rat spermatidal protein TP2 shows GC-rich sequence preference and is zinc dependent. |journal=Biochemistry |volume=34 |issue= 15 |pages= 5143–50 |year= 1995 |pmid= 7711033 |doi=10.1021/bi00015a027 }}
*{{cite journal  | author=Baskaran R, Rao MR |title=Interaction of spermatid-specific protein TP2 with nucleic acids, in vitro. A comparative study with TP1. |journal=J. Biol. Chem. |volume=265 |issue= 34 |pages= 21039-47 |year= 1991 |pmid= 2250010 |doi=  }}
*{{cite journal  |vauthors=Nelson JE, Krawetz SA |title=Characterization of a human locus in transition. |journal=J. Biol. Chem. |volume=269 |issue= 49 |pages= 31067–73 |year= 1995 |pmid= 7983046 |doi=  }}
*{{cite journal  | author=Kundu TK, Rao MR |title=DNA condensation by the rat spermatidal protein TP2 shows GC-rich sequence preference and is zinc dependent. |journal=Biochemistry |volume=34 |issue= 15 |pages= 5143-50 |year= 1995 |pmid= 7711033 |doi=  }}
*{{cite journal  |vauthors=Nelson JE, Krawetz SA |title=Linkage of human spermatid-specific basic nuclear protein genes. Definition and evolution of the P1-->P2-->TP2 locus. |journal=J. Biol. Chem. |volume=268 |issue= 4 |pages= 2932–6 |year= 1993 |pmid= 8428967 |doi=  }}
*{{cite journal  | author=Nelson JE, Krawetz SA |title=Characterization of a human locus in transition. |journal=J. Biol. Chem. |volume=269 |issue= 49 |pages= 31067-73 |year= 1995 |pmid= 7983046 |doi=  }}
*{{cite journal  |vauthors=Kundu TK, Rao MR |title=Zinc dependent recognition of a human CpG island sequence by the mammalian spermatidal protein TP2. |journal=Biochemistry |volume=35 |issue= 49 |pages= 15626–32 |year= 1997 |pmid= 8961924 |doi= 10.1021/bi961271i }}
*{{cite journal  | author=Nelson JE, Krawetz SA |title=Linkage of human spermatid-specific basic nuclear protein genes. Definition and evolution of the P1-->P2-->TP2 locus. |journal=J. Biol. Chem. |volume=268 |issue= 4 |pages= 2932-6 |year= 1993 |pmid= 8428967 |doi=  }}
*{{cite journal  | author=Steger K |title=Expression of mRNA and protein of nucleoproteins during human spermiogenesis |journal=Mol. Hum. Reprod. |volume=4 |issue= 10 |pages= 939–45 |year= 1999 |pmid= 9809674 |doi=10.1093/molehr/4.10.939  |name-list-format=vanc| author2=Klonisch T  | author3=Gavenis K  | display-authors=3  | last4=Drabent  | first4=B  | last5=Doenecke  | first5=D  | last6=Bergmann  | first6=M }}
*{{cite journal  | author=Kundu TK, Rao MR |title=Zinc dependent recognition of a human CpG island sequence by the mammalian spermatidal protein TP2. |journal=Biochemistry |volume=35 |issue= 49 |pages= 15626-32 |year= 1997 |pmid= 8961924 |doi= 10.1021/bi961271i }}
*{{cite journal  |vauthors=Wyckoff GJ, Wang W, Wu CI |title=Rapid evolution of male reproductive genes in the descent of man |journal=Nature |volume=403 |issue= 6767 |pages= 304–9 |year= 2000 |pmid= 10659848 |doi= 10.1038/35002070 }}
*{{cite journal  | author=Steger K, Klonisch T, Gavenis K, ''et al.'' |title=Expression of mRNA and protein of nucleoproteins during human spermiogenesis. |journal=Mol. Hum. Reprod. |volume=4 |issue= 10 |pages= 939-45 |year= 1999 |pmid= 9809674 |doi=  }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Wyckoff GJ, Wang W, Wu CI |title=Rapid evolution of male reproductive genes in the descent of man. |journal=Nature |volume=403 |issue= 6767 |pages= 304-9 |year= 2000 |pmid= 10659848 |doi= 10.1038/35002070 }}
*{{cite journal  |vauthors=Wykes SM, Krawetz SA |title=The structural organization of sperm chromatin |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 29471–7 |year= 2003 |pmid= 12775710 |doi= 10.1074/jbc.M304545200 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Miyagawa Y |title=Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations |journal=J. Androl. |volume=26 |issue= 6 |pages= 779–86 |year= 2006 |pmid= 16291974 |doi= 10.2164/jandrol.05069 |name-list-format=vanc| author2=Nishimura H  | author3=Tsujimura A  | display-authors=3  | last4=Matsuoka  | first4=Y  | last5=Matsumiya  | first5=K  | last6=Okuyama  | first6=A  | last7=Nishimune  | first7=Y  | last8=Tanaka  | first8=H }}
*{{cite journal  | author=Wykes SM, Krawetz SA |title=The structural organization of sperm chromatin. |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 29471-7 |year= 2003 |pmid= 12775710 |doi= 10.1074/jbc.M304545200 }}
*{{cite journal  | author=Jedrzejczak P |title=Quantitative assessment of transition proteins 1, 2 spermatid-specific linker histone H1-like protein transcripts in spermatozoa from normozoospermic and asthenozoospermic men |journal=Arch. Androl. |volume=53 |issue= 4 |pages= 199–205 |year= 2007 |pmid= 17852044 |doi= 10.1080/01485010701426430 |name-list-format=vanc| author2=Kempisty B  | author3=Bryja A  | display-authors=3  | last4=Mostowska  | first4=M.  | last5=Depa-Martynow  | first5=Magdalena  | last6=Pawelczyk  | first6=Leszek  | last7=Jagodzinski  | first7=Pawel Piotr }}
*{{cite journal  | author=Miyagawa Y, Nishimura H, Tsujimura A, ''et al.'' |title=Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations. |journal=J. Androl. |volume=26 |issue= 6 |pages= 779-86 |year= 2006 |pmid= 16291974 |doi= 10.2164/jandrol.05069 }}
*{{cite journal  | author=Jedrzejczak P, Kempisty B, Bryja A, ''et al.'' |title=Quantitative assessment of transition proteins 1, 2 spermatid-specific linker histone H1-like protein transcripts in spermatozoa from normozoospermic and asthenozoospermic men. |journal=Arch. Androl. |volume=53 |issue= 4 |pages= 199-205 |year= 2007 |pmid= 17852044 |doi= 10.1080/01485010701426430 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{WikiDoc Sources}}
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
{{Nucleus}}
 
 
{{gene-16-stub}}

Latest revision as of 09:18, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nuclear transition protein 2 is a protein that in humans is encoded by the TNP2 gene.[1][2][3]

References

  1. ↑ Engel W, Keime S, Kremling H, Hameister H, Schluter G (Nov 1992). "The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome". Cytogenet Cell Genet. 61 (2): 158–9. doi:10.1159/000133397. PMID 1395729.
  2. ↑ Baskaran R, Rao MR (Jan 1991). "Interaction of spermatid-specific protein TP2 with nucleic acids, in vitro. A comparative study with TP1". J Biol Chem. 265 (34): 21039–47. PMID 2250010.
  3. ↑ "Entrez Gene: TNP2 transition protein 2 (during histone to protamine replacement)".

Further reading

  • Schlüter G, Kremling H, Engel W (1992). "The gene for human transition protein 2: nucleotide sequence, assignment to the protamine gene cluster, and evidence for its low expression". Genomics. 14 (2): 377–83. doi:10.1016/S0888-7543(05)80229-0. PMID 1385303.
  • Kundu TK, Rao MR (1995). "DNA condensation by the rat spermatidal protein TP2 shows GC-rich sequence preference and is zinc dependent". Biochemistry. 34 (15): 5143–50. doi:10.1021/bi00015a027. PMID 7711033.
  • Nelson JE, Krawetz SA (1995). "Characterization of a human locus in transition". J. Biol. Chem. 269 (49): 31067–73. PMID 7983046.
  • Nelson JE, Krawetz SA (1993). "Linkage of human spermatid-specific basic nuclear protein genes. Definition and evolution of the P1-->P2-->TP2 locus". J. Biol. Chem. 268 (4): 2932–6. PMID 8428967.
  • Kundu TK, Rao MR (1997). "Zinc dependent recognition of a human CpG island sequence by the mammalian spermatidal protein TP2". Biochemistry. 35 (49): 15626–32. doi:10.1021/bi961271i. PMID 8961924.
  • Steger K, Klonisch T, Gavenis K, et al. (1999). "Expression of mRNA and protein of nucleoproteins during human spermiogenesis". Mol. Hum. Reprod. 4 (10): 939–45. doi:10.1093/molehr/4.10.939. PMID 9809674.
  • Wyckoff GJ, Wang W, Wu CI (2000). "Rapid evolution of male reproductive genes in the descent of man". Nature. 403 (6767): 304–9. doi:10.1038/35002070. PMID 10659848.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wykes SM, Krawetz SA (2003). "The structural organization of sperm chromatin". J. Biol. Chem. 278 (32): 29471–7. doi:10.1074/jbc.M304545200. PMID 12775710.
  • Miyagawa Y, Nishimura H, Tsujimura A, et al. (2006). "Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations". J. Androl. 26 (6): 779–86. doi:10.2164/jandrol.05069. PMID 16291974.
  • Jedrzejczak P, Kempisty B, Bryja A, et al. (2007). "Quantitative assessment of transition proteins 1, 2 spermatid-specific linker histone H1-like protein transcripts in spermatozoa from normozoospermic and asthenozoospermic men". Arch. Androl. 53 (4): 199–205. doi:10.1080/01485010701426430. PMID 17852044.



Retrieved from "https://www.wikidoc.org/index.php?title=TNP2&oldid=1524581"