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'''UDP-glucuronosyltransferase 2B15''' is an [[enzyme]] that in humans is encoded by the ''UGT2B15'' [[gene]].<ref name="pmid7835904">{{cite journal | vauthors = Monaghan G, Clarke DJ, Povey S, See CG, Boxer M, Burchell B | title = Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13 | journal = Genomics | volume = 23 | issue = 2 | pages = 496–9 |date=Feb 1995 | pmid = 7835904 | pmc =  | doi = 10.1006/geno.1994.1531 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7366| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = UDP glucuronosyltransferase 2 family, polypeptide B15
| HGNCid = 12546
| Symbol = UGT2B15
| AltSymbols =; UGT2B8
| OMIM = 600069
| ECnumber = 
| Homologene = 88643
| MGIid = 3576100
| Function = {{GNF_GO|id=GO:0015020 |text = glucuronosyltransferase activity}} {{GNF_GO|id=GO:0016758 |text = transferase activity, transferring hexosyl groups}}
| Component = {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005792 |text = microsome}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006805 |text = xenobiotic metabolic process}} {{GNF_GO|id=GO:0008152 |text = metabolic process}} {{GNF_GO|id=GO:0008202 |text = steroid metabolic process}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7366
    | Hs_Ensembl = 
    | Hs_RefseqProtein = NP_001067
    | Hs_RefseqmRNA = NM_001076
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 243085
    | Mm_Ensembl = ENSMUSG00000035811
    | Mm_RefseqmRNA = NM_172881
    | Mm_RefseqProtein = NP_766469
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 88075453
    | Mm_GenLoc_end = 88086099
    | Mm_Uniprot = 
  }}
}}
'''UDP glucuronosyltransferase 2 family, polypeptide B15''', also known as '''UGT2B15''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7366| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7366| accessdate = }}</ref>
| summary_text = The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).[supplied by OMIM]<ref name="entrez" />
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Coffman BL, Tephly TR, Irshaid YM, ''et al.'' |title=Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase. |journal=Arch. Biochem. Biophys. |volume=281 |issue= 1 |pages= 170-5 |year= 1990 |pmid= 2116769 |doi=  }}
*{{cite journal   |vauthors=Coffman BL, Tephly TR, Irshaid YM, etal |title=Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase. |journal=Arch. Biochem. Biophys. |volume=281 |issue= 1 |pages= 170–5 |year= 1990 |pmid= 2116769 |doi=10.1016/0003-9861(90)90428-2 }}
*{{cite journal  | author=Irshaid YM, Tephly TR |title=Isolation and purification of two human liver UDP-glucuronosyltransferases. |journal=Mol. Pharmacol. |volume=31 |issue= 1 |pages= 27-34 |year= 1987 |pmid= 3100939 |doi=  }}
*{{cite journal  | vauthors=Irshaid YM, Tephly TR |title=Isolation and purification of two human liver UDP-glucuronosyltransferases. |journal=Mol. Pharmacol. |volume=31 |issue= 1 |pages= 27–34 |year= 1987 |pmid= 3100939 |doi=  }}
*{{cite journal | author=Green MD, Clarke DJ, Oturu EM, ''et al.'' |title=Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols. |journal=Arch. Biochem. Biophys. |volume=322 |issue= 2 |pages= 460-8 |year= 1995 |pmid= 7574722 |doi= 10.1006/abbi.1995.1489 }}
*{{cite journal   |vauthors=Green MD, Clarke DJ, Oturu EM, etal |title=Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols. |journal=Arch. Biochem. Biophys. |volume=322 |issue= 2 |pages= 460–8 |year= 1995 |pmid= 7574722 |doi= 10.1006/abbi.1995.1489 }}
*{{cite journal  | author=Green MD, Oturu EM, Tephly TR |title=Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. |journal=Drug Metab. Dispos. |volume=22 |issue= 5 |pages= 799-805 |year= 1995 |pmid= 7835232 |doi=  }}
*{{cite journal  | vauthors=Green MD, Oturu EM, Tephly TR |title=Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. |journal=Drug Metab. Dispos. |volume=22 |issue= 5 |pages= 799–805 |year= 1995 |pmid= 7835232 |doi=  }}
*{{cite journal | author=Monaghan G, Clarke DJ, Povey S, ''et al.'' |title=Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13. |journal=Genomics |volume=23 |issue= 2 |pages= 496-9 |year= 1995 |pmid= 7835904 |doi= 10.1006/geno.1994.1531 }}
*{{cite journal   |vauthors=Chen F, Ritter JK, Wang MG, etal |title=Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms. |journal=Biochemistry |volume=32 |issue= 40 |pages= 10648–57 |year= 1993 |pmid= 8399210 |doi=10.1021/bi00091a015  }}
*{{cite journal | author=Chen F, Ritter JK, Wang MG, ''et al.'' |title=Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms. |journal=Biochemistry |volume=32 |issue= 40 |pages= 10648-57 |year= 1993 |pmid= 8399210 |doi=  }}
*{{cite journal   |vauthors=Guillemette C, Lévesque E, Beaulieu M, etal |title=Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells. |journal=Endocrinology |volume=138 |issue= 7 |pages= 2998–3005 |year= 1997 |pmid= 9202245 |doi=10.1210/en.138.7.2998 }}
*{{cite journal | author=Guillemette C, Lévesque E, Beaulieu M, ''et al.'' |title=Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells. |journal=Endocrinology |volume=138 |issue= 7 |pages= 2998-3005 |year= 1997 |pmid= 9202245 |doi=  }}
*{{cite journal   |vauthors=Lévesque E, Beaulieu M, Green MD, etal |title=Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene. |journal=Pharmacogenetics |volume=7 |issue= 4 |pages= 317–25 |year= 1997 |pmid= 9295060 |doi=10.1097/00008571-199708000-00007 }}
*{{cite journal | author=Lévesque E, Beaulieu M, Green MD, ''et al.'' |title=Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene. |journal=Pharmacogenetics |volume=7 |issue= 4 |pages= 317-25 |year= 1997 |pmid= 9295060 |doi=  }}
*{{cite journal   |vauthors=Strassburg CP, Strassburg A, Nguyen N, etal |title=Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. |journal=Biochem. J. |volume= 338 |issue= 2|pages= 489–98 |year= 1999 |pmid= 10024527 |doi=10.1042/0264-6021:3380489  | pmc=1220077 }}
*{{cite journal | author=Strassburg CP, Strassburg A, Nguyen N, ''et al.'' |title=Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. |journal=Biochem. J. |volume=338 ( Pt 2) |issue= |pages= 489-98 |year= 1999 |pmid= 10024527 |doi= }}
*{{cite journal   |vauthors=Tchernof A, Lévesque E, Beaulieu M, etal |title=Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method. |journal=Clin. Endocrinol. |volume=50 |issue= 5 |pages= 637–42 |year= 1999 |pmid= 10468930 |doi=10.1046/j.1365-2265.1999.00709.x  }}
*{{cite journal | author=Tchernof A, Lévesque E, Beaulieu M, ''et al.'' |title=Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method. |journal=Clin. Endocrinol. (Oxf) |volume=50 |issue= 5 |pages= 637-42 |year= 1999 |pmid= 10468930 |doi= }}
*{{cite journal   |vauthors=Strassburg CP, Kneip S, Topp J, etal |title=Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36164–71 |year= 2000 |pmid= 10748067 |doi= 10.1074/jbc.M002180200 }}
*{{cite journal | author=Strassburg CP, Kneip S, Topp J, ''et al.'' |title=Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36164-71 |year= 2000 |pmid= 10748067 |doi= 10.1074/jbc.M002180200 }}
*{{cite journal   |vauthors=Gsur A, Preyer M, Haidinger G, etal |title=A polymorphism in the UDP-Glucuronosyltransferase 2B15 gene (D85Y) is not associated with prostate cancer risk. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=11 |issue= 5 |pages= 497–8 |year= 2002 |pmid= 12010866 |doi= }}
*{{cite journal | author=Gsur A, Preyer M, Haidinger G, ''et al.'' |title=A polymorphism in the UDP-Glucuronosyltransferase 2B15 gene (D85Y) is not associated with prostate cancer risk. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=11 |issue= 5 |pages= 497-8 |year= 2002 |pmid= 12010866 |doi= }}
*{{cite journal   |vauthors=Iida A, Saito S, Sekine A, etal |title=Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8. |journal=J. Hum. Genet. |volume=47 |issue= 10 |pages= 505–10 |year= 2002 |pmid= 12376738 |doi= 10.1007/s100380200075 }}
*{{cite journal | author=Iida A, Saito S, Sekine A, ''et al.'' |title=Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8. |journal=J. Hum. Genet. |volume=47 |issue= 10 |pages= 505-10 |year= 2002 |pmid= 12376738 |doi= 10.1007/s100380200075 }}
*{{cite journal   |vauthors=Court MH, Duan SX, Guillemette C, etal |title=Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9. |journal=Drug Metab. Dispos. |volume=30 |issue= 11 |pages= 1257–65 |year= 2003 |pmid= 12386133 |doi=10.1124/dmd.30.11.1257  }}
*{{cite journal  | author=Court MH, Duan SX, Guillemette C, ''et al.'' |title=Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9. |journal=Drug Metab. Dispos. |volume=30 |issue= 11 |pages= 1257-65 |year= 2003 |pmid= 12386133 |doi=  }}
*{{cite journal  | vauthors=Kanaya J, Takashima M, Koh E, Namiki M |title=Androgen-independent growth in LNCaP cell lines and steroid uridine diphosphate-glucuronosyltransferase expression. |journal=Asian J. Androl. |volume=5 |issue= 1 |pages= 9–13 |year= 2003 |pmid= 12646996 |doi=  }}
*{{cite journal | author=Kanaya J, Takashima M, Koh E, Namiki M |title=Androgen-independent growth in LNCaP cell lines and steroid uridine diphosphate-glucuronosyltransferase expression. |journal=Asian J. Androl. |volume=5 |issue= 1 |pages= 9-13 |year= 2003 |pmid= 12646996 |doi=  }}
*{{cite journal   |vauthors=Zhang JY, Zhan J, Cook CS, etal |title=Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism. |journal=Drug Metab. Dispos. |volume=31 |issue= 5 |pages= 652–8 |year= 2003 |pmid= 12695355 |doi=10.1124/dmd.31.5.652 }}
*{{cite journal  | author=Zhang JY, Zhan J, Cook CS, ''et al.'' |title=Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism. |journal=Drug Metab. Dispos. |volume=31 |issue= 5 |pages= 652-8 |year= 2003 |pmid= 12695355 |doi=  }}
*{{cite journal  | vauthors=Tomboc M, Witchel SF |title=Frequencies of the D85 and Y85 variants of UGT2B15 in children and adolescent girls with hyperandrogenism. |journal=J. Pediatr. Endocrinol. Metab. |volume=16 |issue= 5 |pages= 719–26 |year= 2003 |pmid= 12880121 |doi=  10.1515/jpem.2003.16.5.719}}
*{{cite journal | author=Tomboc M, Witchel SF |title=Frequencies of the D85 and Y85 variants of UGT2B15 in children and adolescent girls with hyperandrogenism. |journal=J. Pediatr. Endocrinol. Metab. |volume=16 |issue= 5 |pages= 719-26 |year= 2003 |pmid= 12880121 |doi= }}
*{{cite journal   |vauthors=Court MH, Hao Q, Krishnaswamy S, etal |title=UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver. |journal=J. Pharmacol. Exp. Ther. |volume=310 |issue= 2 |pages= 656–65 |year= 2005 |pmid= 15044558 |doi= 10.1124/jpet.104.067660 }}
*{{cite journal | author=Court MH, Hao Q, Krishnaswamy S, ''et al.'' |title=UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver. |journal=J. Pharmacol. Exp. Ther. |volume=310 |issue= 2 |pages= 656-65 |year= 2005 |pmid= 15044558 |doi= 10.1124/jpet.104.067660 }}
*{{cite journal   |vauthors=Toide K, Umeda S, Yamazaki H, etal |title=A major genotype in UDP-glucuronosyltransferase 2B15. |journal=Drug Metab. Pharmacokinet. |volume=17 |issue= 2 |pages= 164–6 |year= 2005 |pmid= 15618667 |doi=10.2133/dmpk.17.164  }}
*{{cite journal  | author=Toide K, Umeda S, Yamazaki H, ''et al.'' |title=A major genotype in UDP-glucuronosyltransferase 2B15. |journal=Drug Metab. Pharmacokinet. |volume=17 |issue= 2 |pages= 164-6 |year= 2005 |pmid= 15618667 |doi= }}
*{{cite journal  | vauthors=Chouinard S, Pelletier G, Bélanger A, Barbier O |title=Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. |journal=Endocr. Res. |volume=30 |issue= 4 |pages= 717–25 |year= 2005 |pmid= 15666817 |doi=10.1081/ERC-200044014 }}
*{{cite journal  | author=Chouinard S, Pelletier G, Bélanger A, Barbier O |title=Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. |journal=Endocr. Res. |volume=30 |issue= 4 |pages= 717-25 |year= 2005 |pmid= 15666817 |doi= }}
}}
}}
{{refend}}
{{refend}}
{{Glycosyltransferases}}
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Latest revision as of 09:43, 17 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

UDP-glucuronosyltransferase 2B15 is an enzyme that in humans is encoded by the UGT2B15 gene.[1][2]

The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).[supplied by OMIM][2]

References

  1. ↑ Monaghan G, Clarke DJ, Povey S, See CG, Boxer M, Burchell B (Feb 1995). "Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13". Genomics. 23 (2): 496–9. doi:10.1006/geno.1994.1531. PMID 7835904.
  2. ↑ 2.0 2.1 "Entrez Gene: UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15".

Further reading

  • Coffman BL, Tephly TR, Irshaid YM, et al. (1990). "Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase". Arch. Biochem. Biophys. 281 (1): 170–5. doi:10.1016/0003-9861(90)90428-2. PMID 2116769.
  • Irshaid YM, Tephly TR (1987). "Isolation and purification of two human liver UDP-glucuronosyltransferases". Mol. Pharmacol. 31 (1): 27–34. PMID 3100939.
  • Green MD, Clarke DJ, Oturu EM, et al. (1995). "Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols". Arch. Biochem. Biophys. 322 (2): 460–8. doi:10.1006/abbi.1995.1489. PMID 7574722.
  • Green MD, Oturu EM, Tephly TR (1995). "Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates". Drug Metab. Dispos. 22 (5): 799–805. PMID 7835232.
  • Chen F, Ritter JK, Wang MG, et al. (1993). "Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms". Biochemistry. 32 (40): 10648–57. doi:10.1021/bi00091a015. PMID 8399210.
  • Guillemette C, Lévesque E, Beaulieu M, et al. (1997). "Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells". Endocrinology. 138 (7): 2998–3005. doi:10.1210/en.138.7.2998. PMID 9202245.
  • Lévesque E, Beaulieu M, Green MD, et al. (1997). "Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene". Pharmacogenetics. 7 (4): 317–25. doi:10.1097/00008571-199708000-00007. PMID 9295060.
  • Strassburg CP, Strassburg A, Nguyen N, et al. (1999). "Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus". Biochem. J. 338 (2): 489–98. doi:10.1042/0264-6021:3380489. PMC 1220077. PMID 10024527.
  • Tchernof A, Lévesque E, Beaulieu M, et al. (1999). "Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method". Clin. Endocrinol. 50 (5): 637–42. doi:10.1046/j.1365-2265.1999.00709.x. PMID 10468930.
  • Strassburg CP, Kneip S, Topp J, et al. (2000). "Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine". J. Biol. Chem. 275 (46): 36164–71. doi:10.1074/jbc.M002180200. PMID 10748067.
  • Gsur A, Preyer M, Haidinger G, et al. (2002). "A polymorphism in the UDP-Glucuronosyltransferase 2B15 gene (D85Y) is not associated with prostate cancer risk". Cancer Epidemiol. Biomarkers Prev. 11 (5): 497–8. PMID 12010866.
  • Iida A, Saito S, Sekine A, et al. (2002). "Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8". J. Hum. Genet. 47 (10): 505–10. doi:10.1007/s100380200075. PMID 12376738.
  • Court MH, Duan SX, Guillemette C, et al. (2003). "Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9". Drug Metab. Dispos. 30 (11): 1257–65. doi:10.1124/dmd.30.11.1257. PMID 12386133.
  • Kanaya J, Takashima M, Koh E, Namiki M (2003). "Androgen-independent growth in LNCaP cell lines and steroid uridine diphosphate-glucuronosyltransferase expression". Asian J. Androl. 5 (1): 9–13. PMID 12646996.
  • Zhang JY, Zhan J, Cook CS, et al. (2003). "Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism". Drug Metab. Dispos. 31 (5): 652–8. doi:10.1124/dmd.31.5.652. PMID 12695355.
  • Tomboc M, Witchel SF (2003). "Frequencies of the D85 and Y85 variants of UGT2B15 in children and adolescent girls with hyperandrogenism". J. Pediatr. Endocrinol. Metab. 16 (5): 719–26. doi:10.1515/jpem.2003.16.5.719. PMID 12880121.
  • Court MH, Hao Q, Krishnaswamy S, et al. (2005). "UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver". J. Pharmacol. Exp. Ther. 310 (2): 656–65. doi:10.1124/jpet.104.067660. PMID 15044558.
  • Toide K, Umeda S, Yamazaki H, et al. (2005). "A major genotype in UDP-glucuronosyltransferase 2B15". Drug Metab. Pharmacokinet. 17 (2): 164–6. doi:10.2133/dmpk.17.164. PMID 15618667.
  • Chouinard S, Pelletier G, Bélanger A, Barbier O (2005). "Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium". Endocr. Res. 30 (4): 717–25. doi:10.1081/ERC-200044014. PMID 15666817.



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