VTI1B: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Vesicle transport through interaction with t-SNAREs homolog 1B''' is a [[protein]] that in humans is encoded by the ''VTI1B'' [[gene]].<ref name="pmid9636656">{{cite journal | vauthors = Li HC, Tahara H, Tsuyama N, Ide T | title = A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts | journal = Biochem Biophys Res Commun | volume = 247 | issue = 1 | pages = 70–4 | date = July 1998 | pmid = 9636656 | pmc =  | doi = 10.1006/bbrc.1998.8737 }}</ref><ref name="pmid9446565">{{cite journal | vauthors = Fischer von Mollard G, Stevens TH | title = A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways | journal = J Biol Chem | volume = 273 | issue = 5 | pages = 2624–30 | date = February 1998 | pmid = 9446565 | pmc = | doi = 10.1074/jbc.273.5.2624 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10490| accessdate = }}</ref>
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| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image = PBB_Protein_VTI1B_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1gl2.
| PDB = {{PDB2|1gl2}}
| Name = Vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
| HGNCid = 17793
| Symbol = VTI1B
| AltSymbols =; VTI1; VTI1L; VTI2
| OMIM = 603207
| ECnumber = 
| Homologene = 38178
| MGIid = 1855688
| GeneAtlas_image1 = PBB_GE_VTI1B_209452_s_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}} {{GNF_GO|id=GO:0006904 |text = vesicle docking during exocytosis}} {{GNF_GO|id=GO:0006944 |text = membrane fusion}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0016192 |text = vesicle-mediated transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10490
    | Hs_Ensembl = ENSG00000100568
    | Hs_RefseqProtein = NP_006361
    | Hs_RefseqmRNA = NM_006370
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 67186985
    | Hs_GenLoc_end = 67211096
    | Hs_Uniprot = Q9UEU0
    | Mm_EntrezGene = 53612
    | Mm_Ensembl = ENSMUSG00000021124
    | Mm_RefseqmRNA = NM_016800
    | Mm_RefseqProtein = NP_058080
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 80074862
    | Mm_GenLoc_end = 80091289
    | Mm_Uniprot = Q3TUP8
  }}
}}
'''Vesicle transport through interaction with t-SNAREs homolog 1B (yeast)''', also known as '''VTI1B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10490| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
VTI1B has been shown to [[Protein-protein interaction|interact]] with [[STX8]].<ref name=pmid16189514>{{cite journal|authorlink30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = [[Nature (journal)|Nature]] | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R }}</ref><ref name=pmid10683148>{{cite journal | vauthors = Subramaniam VN, Loh E, Horstmann H, Habermann A, Xu Y, Coe J, Griffiths G, Hong W | title = Preferential association of syntaxin 8 with the early endosome | journal = J. Cell Sci. | volume = 113 | issue = 6 | pages = 997–1008 | date = March 2000 | pmid = 10683148 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Subramaniam VN, Loh E, Horstmann H, Habermann A, Xu Y, Coe J, Griffiths G, Hong W | title = Preferential association of syntaxin 8 with the early endosome | journal = J. Cell Sci. | volume = 113 | issue = 6 | pages = 997–1008 | year = 2000 | pmid = 10683148 | doi =  }}
| citations =
* {{cite journal | vauthors = Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF, Jahn R | title = A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function | journal = EMBO J. | volume = 19 | issue = 23 | pages = 6453–64 | year = 2001 | pmid = 11101518 | pmc = 305878 | doi = 10.1093/emboj/19.23.6453 }}
*{{cite journal  | author=Fischer von Mollard G, Stevens TH |title=A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways. |journal=J. Biol. Chem. |volume=273 |issue= 5 |pages= 2624-30 |year= 1998 |pmid= 9446565 |doi=  }}
* {{cite journal | vauthors = Wade N, Bryant NJ, Connolly LM, Simpson RJ, Luzio JP, Piper RC, James DE | title = Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells | journal = J. Biol. Chem. | volume = 276 | issue = 23 | pages = 19820–7 | year = 2001 | pmid = 11278762 | doi = 10.1074/jbc.M010838200 }}
*{{cite journal  | author=Li HC, Tahara H, Tsuyama N, Ide T |title=A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts. |journal=Biochem. Biophys. Res. Commun. |volume=247 |issue= 1 |pages= 70-4 |year= 1998 |pmid= 9636656 |doi= 10.1006/bbrc.1998.8737 }}
* {{cite journal | vauthors = Antonin W, Fasshauer D, Becker S, Jahn R, Schneider TR | title = Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs | journal = Nat. Struct. Biol. | volume = 9 | issue = 2 | pages = 107–11 | year = 2002 | pmid = 11786915 | doi = 10.1038/nsb746 }}
*{{cite journal | author=Subramaniam VN, Loh E, Horstmann H, ''et al.'' |title=Preferential association of syntaxin 8 with the early endosome. |journal=J. Cell. Sci. |volume=113 ( Pt 6) |issue= |pages= 997-1008 |year= 2000 |pmid= 10683148 |doi=  }}
* {{cite journal | vauthors = Kreykenbohm V, Wenzel D, Antonin W, Atlachkine V, von Mollard GF | title = The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners | journal = Eur. J. Cell Biol. | volume = 81 | issue = 5 | pages = 273–80 | year = 2003 | pmid = 12067063 | doi = 10.1078/0171-9335-00247 }}
*{{cite journal | author=Antonin W, Holroyd C, Fasshauer D, ''et al.'' |title=A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6453-64 |year= 2001 |pmid= 11101518 |doi= 10.1093/emboj/19.23.6453 }}
* {{cite journal | vauthors = Antonin W, Dulubova I, Arac D, Pabst S, Plitzner J, Rizo J, Jahn R | title = The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly | journal = J. Biol. Chem. | volume = 277 | issue = 39 | pages = 36449–56 | year = 2002 | pmid = 12114520 | doi = 10.1074/jbc.M204369200 }}
*{{cite journal | author=Wade N, Bryant NJ, Connolly LM, ''et al.'' |title=Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 19820-7 |year= 2001 |pmid= 11278762 |doi= 10.1074/jbc.M010838200 }}
* {{cite journal | vauthors = Bogdanovic A, Bennett N, Kieffer S, Louwagie M, Morio T, Garin J, Satre M, Bruckert F | title = Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum | journal = Biochem. J. | volume = 368 | issue = Pt 1 | pages = 29–39 | year = 2002 | pmid = 12175335 | pmc = 1222979 | doi = 10.1042/BJ20020845 }}
*{{cite journal | author=Antonin W, Fasshauer D, Becker S, ''et al.'' |title=Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. |journal=Nat. Struct. Biol. |volume=9 |issue= 2 |pages= 107-11 |year= 2002 |pmid= 11786915 |doi= 10.1038/nsb746 }}
* {{cite journal | vauthors = Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J, Proux-Gillardeaux V, Daviet L, Formstecher E, Hamburger A, Filippini F, D'Esposito M, Galli T | title = A dual mechanism controlling the localization and function of exocytic v-SNAREs | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 100 | issue = 15 | pages = 9011–6 | year = 2003 | pmid = 12853575 | pmc = 166429 | doi = 10.1073/pnas.1431910100 | bibcode = 2003PNAS..100.9011M }}
*{{cite journal | author=Kreykenbohm V, Wenzel D, Antonin W, ''et al.'' |title=The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners. |journal=Eur. J. Cell Biol. |volume=81 |issue= 5 |pages= 273-80 |year= 2003 |pmid= 12067063 |doi= }}
* {{cite journal | vauthors = Yan Q, Sun W, McNew JA, Vida TA, Bean AJ | title = Ca2+ and N-ethylmaleimide-sensitive factor differentially regulate disassembly of SNARE complexes on early endosomes | journal = J. Biol. Chem. | volume = 279 | issue = 18 | pages = 18270–6 | year = 2004 | pmid = 14769786 | doi = 10.1074/jbc.M400093200 }}
*{{cite journal | author=Antonin W, Dulubova I, Arac D, ''et al.'' |title=The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly. |journal=J. Biol. Chem. |volume=277 |issue= 39 |pages= 36449-56 |year= 2002 |pmid= 12114520 |doi= 10.1074/jbc.M204369200 }}
* {{cite journal | vauthors = Hirst J, Miller SE, Taylor MJ, von Mollard GF, Robinson MS | title = EpsinR is an adaptor for the SNARE protein Vti1b | journal = Mol. Biol. Cell | volume = 15 | issue = 12 | pages = 5593–602 | year = 2005 | pmid = 15371541 | pmc = 532037 | doi = 10.1091/mbc.E04-06-0468 }}
*{{cite journal | author=Bogdanovic A, Bennett N, Kieffer S, ''et al.'' |title=Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum. |journal=Biochem. J. |volume=368 |issue= Pt 1 |pages= 29-39 |year= 2002 |pmid= 12175335 |doi= 10.1042/BJ20020845 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Martinez-Arca S, Rudge R, Vacca M, ''et al.'' |title=A dual mechanism controlling the localization and function of exocytic v-SNAREs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 15 |pages= 9011-6 |year= 2003 |pmid= 12853575 |doi= 10.1073/pnas.1431910100 }}
*{{cite journal | author=Yan Q, Sun W, McNew JA, ''et al.'' |title=Ca2+ and N-ethylmaleimide-sensitive factor differentially regulate disassembly of SNARE complexes on early endosomes. |journal=J. Biol. Chem. |volume=279 |issue= 18 |pages= 18270-6 |year= 2004 |pmid= 14769786 |doi= 10.1074/jbc.M400093200 }}
*{{cite journal | author=Hirst J, Miller SE, Taylor MJ, ''et al.'' |title=EpsinR is an adaptor for the SNARE protein Vti1b. |journal=Mol. Biol. Cell |volume=15 |issue= 12 |pages= 5593-602 |year= 2005 |pmid= 15371541 |doi= 10.1091/mbc.E04-06-0468 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{PDB Gallery|geneid=10490}}
{{WikiDoc Sources}}
 
 
{{gene-14-stub}}

Latest revision as of 06:28, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Vesicle transport through interaction with t-SNAREs homolog 1B is a protein that in humans is encoded by the VTI1B gene.[1][2][3]

Interactions

VTI1B has been shown to interact with STX8.[4][5]

References

  1. ↑ Li HC, Tahara H, Tsuyama N, Ide T (July 1998). "A hVti1 homologue: its expression depends on population doubling levels in both normal and SV40-transformed human fibroblasts". Biochem Biophys Res Commun. 247 (1): 70–4. doi:10.1006/bbrc.1998.8737. PMID 9636656.
  2. ↑ Fischer von Mollard G, Stevens TH (February 1998). "A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways". J Biol Chem. 273 (5): 2624–30. doi:10.1074/jbc.273.5.2624. PMID 9446565.
  3. ↑ "Entrez Gene: VTI1B vesicle transport through interaction with t-SNAREs homolog 1B (yeast)".
  4. ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
  5. ↑ Subramaniam VN, Loh E, Horstmann H, Habermann A, Xu Y, Coe J, Griffiths G, Hong W (March 2000). "Preferential association of syntaxin 8 with the early endosome". J. Cell Sci. 113 (6): 997–1008. PMID 10683148.

Further reading


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