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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Zinc finger MYM-type protein 2''' is a [[protein]] that in humans is encoded by the ''ZMYM2'' [[gene]].<ref name="pmid9499416">{{cite journal | vauthors = Smedley D, Hamoudi R, Clark J, Warren W, Abdul-Rauf M, Somers G, Venter D, Fagan K, Cooper C, Shipley J | title = The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP | journal = Human Molecular Genetics | volume = 7 | issue = 4 | pages = 637–42 | date = April 1998 | pmid = 9499416 | pmc =  | doi = 10.1093/hmg/7.4.637 }}</ref><ref name="pmid9425908">{{cite journal | vauthors = Xiao S, Nalabolu SR, Aster JC, Ma J, Abruzzo L, Jaffe ES, Stone R, Weissman SM, Hudson TJ, Fletcher JA | title = FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome | journal = Nature Genetics | volume = 18 | issue = 1 | pages = 84–7 | date = January 1998 | pmid = 9425908 | pmc =  | doi = 10.1038/ng0198-84 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ZMYM2 zinc finger, MYM-type 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7750| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== See also ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Zinc finger, MYM-type 2
| HGNCid = 12989
| Symbol = ZMYM2
| AltSymbols =; FIM; MYM; RAMP; SCLL; ZNF198
| OMIM = 602221
| ECnumber = 
| Homologene = 12631
| MGIid = 1923257
| GeneAtlas_image1 = PBB_GE_ZMYM2_202778_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_ZMYM2_210281_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_ZMYM2_210282_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0008150 |text = biological_process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7750
    | Hs_Ensembl = ENSG00000121741
    | Hs_RefseqProtein = NP_003444
    | Hs_RefseqmRNA = NM_003453
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 13
    | Hs_GenLoc_start = 19430810
    | Hs_GenLoc_end = 19561253
    | Hs_Uniprot = Q9UBW7
    | Mm_EntrezGene = 76007
    | Mm_Ensembl = ENSMUSG00000021945
    | Mm_RefseqmRNA = NM_029498
    | Mm_RefseqProtein = NP_083774
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 14
    | Mm_GenLoc_start = 55841904
    | Mm_GenLoc_end = 55914459
    | Mm_Uniprot = Q3UZ13
  }}
}}
'''Zinc finger, MYM-type 2''', also known as '''ZMYM2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZMYM2 zinc finger, MYM-type 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7750| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
* [[Chromosome 13 (human)]]
{{PBB_Summary
* [[Myeloproliferative neoplasm]]
| section_title =
* [[Zinc finger protein]]
| summary_text =
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Bonaldo MF, Lennon G, Soares MB | title = Normalization and subtraction: two approaches to facilitate gene discovery | journal = Genome Research | volume = 6 | issue = 9 | pages = 791–806 | date = September 1996 | pmid = 8889548 | doi = 10.1101/gr.6.9.791 }}
| citations =
* {{cite journal | vauthors = Popovici C, Adélaïde J, Ollendorff V, Chaffanet M, Guasch G, Jacrot M, Leroux D, Birnbaum D, Pébusque MJ | title = Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13) | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 10 | pages = 5712–7 | date = May 1998 | pmid = 9576949 | pmc = 20444 | doi = 10.1073/pnas.95.10.5712 }}
*{{cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
* {{cite journal | vauthors = Still IH, Cowell JK | title = The t(8;13) atypical myeloproliferative disorder: further analysis of the ZNF198 gene and lack of evidence for multiple genes disrupted on chromosome 13 | journal = Blood | volume = 92 | issue = 4 | pages = 1456–8 | date = August 1998 | pmid = 9694738 | doi =  }}
*{{cite journal  | author=Xiao S, Nalabolu SR, Aster JC, ''et al.'' |title=FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome. |journal=Nat. Genet. |volume=18 |issue= 1 |pages= 84-7 |year= 1998 |pmid= 9425908 |doi= 10.1038/ng0198-84 }}
* {{cite journal | vauthors = Reiter A, Sohal J, Kulkarni S, Chase A, Macdonald DH, Aguiar RC, Gonçalves C, Hernandez JM, Jennings BA, Goldman JM, Cross NC | title = Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome | journal = Blood | volume = 92 | issue = 5 | pages = 1735–42 | date = September 1998 | pmid = 9716603 | doi =  }}
*{{cite journal  | author=Smedley D, Hamoudi R, Clark J, ''et al.'' |title=The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP. |journal=Hum. Mol. Genet. |volume=7 |issue= 4 |pages= 637-42 |year= 1998 |pmid= 9499416 |doi=  }}
* {{cite journal | vauthors = Kulkarni S, Reiter A, Smedley D, Goldman JM, Cross NC | title = The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome | journal = Genomics | volume = 55 | issue = 1 | pages = 118–21 | date = January 1999 | pmid = 9889006 | doi = 10.1006/geno.1998.5634 }}
*{{cite journal | author=Popovici C, Adélaïde J, Ollendorff V, ''et al.'' |title=Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13). |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 10 |pages= 5712-7 |year= 1998 |pmid= 9576949 |doi= }}
* {{cite journal | vauthors = Ollendorff V, Guasch G, Isnardon D, Galindo R, Birnbaum D, Pébusque MJ | title = Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation | journal = The Journal of Biological Chemistry | volume = 274 | issue = 38 | pages = 26922–30 | date = September 1999 | pmid = 10480903 | doi = 10.1074/jbc.274.38.26922 }}
*{{cite journal | author=Still IH, Cowell JK |title=The t(8;13) atypical myeloproliferative disorder: further analysis of the ZNF198 gene and lack of evidence for multiple genes disrupted on chromosome 13. |journal=Blood |volume=92 |issue= 4 |pages= 1456-8 |year= 1998 |pmid= 9694738 |doi=  }}
* {{cite journal | vauthors = Matsumoto K, Morita K, Takada S, Sakura T, Shiozaki H, Murakami H, Miyawaki S | title = A chronic myelogenous leukemia-like myeloproliferative disorder accompanied by T-cell lymphoblastic lymphoma with chromosome translocation t(8;13)(p11;q12): a Japanese case | journal = International Journal of Hematology | volume = 70 | issue = 4 | pages = 278–82 | date = December 1999 | pmid = 10643154 | doi =  }}
*{{cite journal | author=Reiter A, Sohal J, Kulkarni S, ''et al.'' |title=Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome. |journal=Blood |volume=92 |issue= 5 |pages= 1735-42 |year= 1998 |pmid= 9716603 |doi=  }}
* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = November 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
*{{cite journal | author=Kulkarni S, Reiter A, Smedley D, ''et al.'' |title=The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome. |journal=Genomics |volume=55 |issue= 1 |pages= 118-21 |year= 1999 |pmid= 9889006 |doi= 10.1006/geno.1998.5634 }}
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = March 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
*{{cite journal | author=Ollendorff V, Guasch G, Isnardon D, ''et al.'' |title=Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation. |journal=J. Biol. Chem. |volume=274 |issue= 38 |pages= 26922-30 |year= 1999 |pmid= 10480903 |doi= }}
* {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Reports | volume = 1 | issue = 3 | pages = 287–92 | date = September 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }}
*{{cite journal | author=Matsumoto K, Morita K, Takada S, ''et al.'' |title=A chronic myelogenous leukemia-like myeloproliferative disorder accompanied by T-cell lymphoblastic lymphoma with chromosome translocation t(8;13)(p11;q12): a Japanese case. |journal=Int. J. Hematol. |volume=70 |issue= 4 |pages= 278-82 |year= 2000 |pmid= 10643154 |doi=  }}
* {{cite journal | vauthors = Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R | title = A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes | journal = The Journal of Biological Chemistry | volume = 278 | issue = 9 | pages = 7234–9 | date = February 2003 | pmid = 12493763 | doi = 10.1074/jbc.M208992200 }}
*{{cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi= }}
* {{cite journal | vauthors = Baumann H, Kunapuli P, Tracy E, Cowell JK | title = The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors | journal = The Journal of Biological Chemistry | volume = 278 | issue = 18 | pages = 16198–208 | date = May 2003 | pmid = 12594223 | doi = 10.1074/jbc.M300018200 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
* {{cite journal | vauthors = Kunapuli P, Somerville R, Still IH, Cowell JK | title = ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins | journal = Oncogene | volume = 22 | issue = 22 | pages = 3417–23 | date = May 2003 | pmid = 12776193 | doi = 10.1038/sj.onc.1206408 }}
*{{cite journal | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
* {{cite journal | vauthors = Warner DR, Roberts EA, Greene RM, Pisano MM | title = Identification of novel Smad binding proteins | journal = Biochemical and Biophysical Research Communications | volume = 312 | issue = 4 | pages = 1185–90 | date = December 2003 | pmid = 14651998 | doi = 10.1016/j.bbrc.2003.11.049 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Research | volume = 14 | issue = 7 | pages = 1324–32 | date = July 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}
*{{cite journal  | author=Hakimi MA, Dong Y, Lane WS, ''et al.'' |title=A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7234-9 |year= 2003 |pmid= 12493763 |doi= 10.1074/jbc.M208992200 }}
* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}
*{{cite journal | author=Baumann H, Kunapuli P, Tracy E, Cowell JK |title=The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors. |journal=J. Biol. Chem. |volume=278 |issue= 18 |pages= 16198-208 |year= 2003 |pmid= 12594223 |doi= 10.1074/jbc.M300018200 }}
*{{cite journal | author=Kunapuli P, Somerville R, Still IH, Cowell JK |title=ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins. |journal=Oncogene |volume=22 |issue= 22 |pages= 3417-23 |year= 2003 |pmid= 12776193 |doi= 10.1038/sj.onc.1206408 }}
*{{cite journal | author=Warner DR, Roberts EA, Greene RM, Pisano MM |title=Identification of novel Smad binding proteins. |journal=Biochem. Biophys. Res. Commun. |volume=312 |issue= 4 |pages= 1185-90 |year= 2004 |pmid= 14651998 |doi= }}
*{{cite journal  | author=Dunham A, Matthews LH, Burton J, ''et al.'' |title=The DNA sequence and analysis of human chromosome 13. |journal=Nature |volume=428 |issue= 6982 |pages= 522-8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 }}
*{{cite journal | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
 
{{WikiDoc Sources}}
{{gene-13-stub}}

Latest revision as of 01:09, 19 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

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Ensembl

n/a

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UniProt

n/a

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RefSeq (mRNA)

n/a

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger MYM-type protein 2 is a protein that in humans is encoded by the ZMYM2 gene.[1][2][3]

See also

References

  1. ↑ Smedley D, Hamoudi R, Clark J, Warren W, Abdul-Rauf M, Somers G, Venter D, Fagan K, Cooper C, Shipley J (April 1998). "The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP". Human Molecular Genetics. 7 (4): 637–42. doi:10.1093/hmg/7.4.637. PMID 9499416.
  2. ↑ Xiao S, Nalabolu SR, Aster JC, Ma J, Abruzzo L, Jaffe ES, Stone R, Weissman SM, Hudson TJ, Fletcher JA (January 1998). "FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome". Nature Genetics. 18 (1): 84–7. doi:10.1038/ng0198-84. PMID 9425908.
  3. ↑ "Entrez Gene: ZMYM2 zinc finger, MYM-type 2".

Further reading


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