Gallbladder cancer classification: Difference between revisions
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{{Gallbladder cancer}} | {{Gallbladder cancer}} | ||
{{CMG}} | {{CMG}}{{AE}}{{VKG}} | ||
==Overview== | ==Overview== | ||
[[Gallbladder cancer]] may be classified according to [[World Health Organization|WHO]] into various subtypes like [[adenocarcinoma]], [[papillary]] adenocarcinoma, [[mucinous]] adenocarcinoma, [[signet ring cell carcinoma]], [[adenosquamous carcinoma]], [[squamous cell]] [[carcinoma]], [[neuroendocrine]] carcinoma, [[small cell carcinoma]], [[undifferentiated]] carcinoma, [[spindle cell]] undifferentiated carcinoma, giant cell [[undifferentiated]] carcinoma. | |||
==Classification== | ==Classification== | ||
[[Gallbladder carcinoma]] may be classified according to histology into following subtypes.<ref name="JainMathur2013">{{cite journal|last1=Jain|first1=Deepali|last2=Mathur|first2=SandeepR|last3=Sharma|first3=Atul|last4=Yadav|first4=Rajni|last5=Iyer|first5=VenkateswaranK|title=Gallbladder carcinoma: An attempt of WHO histological classification on fine needle aspiration material|journal=CytoJournal|volume=10|issue=1|year=2013|pages=12|issn=1742-6413|doi=10.4103/1742-6413.113627}}</ref> | |||
{| class="wikitable" | |||
| style="background:#4479BA; color: #FFFFFF;" + |'''SUBTYPE''' | |||
| style="background:#4479BA; color: #FFFFFF;" + |'''HISTOLOGICAL FEATURES''' | |||
|- | |||
![[Adenocarcinoma]] | |||
|Sheets, cohesive fragments, [[acini]], and [[mucin]] | |||
|- | |||
![[Papillary]] adenocarcinoma | |||
|Pleomorphism and papillary fragments with vascular core | |||
|- | |||
![[Mucinous]] adenocarcinoma | |||
|Single cells or cluster and [[extracellular]] mucin | |||
|- | |||
![[Signet ring cell carcinoma]] | |||
|[[Intracellular]] mucin with signet ring cells | |||
|- | |||
![[Adenosquamous carcinoma]] | |||
|Mixture of [[glandular]] and [[squamous]] components | |||
|- | |||
![[Squamous cell carcinoma]] | |||
|[[Necrosis]], tadpole cells and atypical [[keratinized]] cells | |||
|- | |||
![[Neuroendocrine]] carcinoma | |||
|Salt and pepper [[chromatin]],anisonucleosis and rosettes | |||
|- | |||
![[Small cell carcinoma]] | |||
|Absent [[cytoplasm]], Smudge cells, and [[mitoses]] | |||
|- | |||
![[Undifferentiated]] carcinoma | |||
|[[Pleomorphic]] cells, abundant [[necrosis]] | |||
|- | |||
![[Spindle]] cell undifferentiated carcinoma | |||
|Undifferciated type with prominent [[spindle]] cells | |||
|- | |||
!Gaint cell undifferentiated carcinoma | |||
|[[Undifferentiated]] type with predominant giant cells | |||
|} | |||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
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Latest revision as of 00:09, 13 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Gallbladder cancer may be classified according to WHO into various subtypes like adenocarcinoma, papillary adenocarcinoma, mucinous adenocarcinoma, signet ring cell carcinoma, adenosquamous carcinoma, squamous cell carcinoma, neuroendocrine carcinoma, small cell carcinoma, undifferentiated carcinoma, spindle cell undifferentiated carcinoma, giant cell undifferentiated carcinoma.
Classification
Gallbladder carcinoma may be classified according to histology into following subtypes.[1]
| SUBTYPE | HISTOLOGICAL FEATURES |
| Adenocarcinoma | Sheets, cohesive fragments, acini, and mucin |
|---|---|
| Papillary adenocarcinoma | Pleomorphism and papillary fragments with vascular core |
| Mucinous adenocarcinoma | Single cells or cluster and extracellular mucin |
| Signet ring cell carcinoma | Intracellular mucin with signet ring cells |
| Adenosquamous carcinoma | Mixture of glandular and squamous components |
| Squamous cell carcinoma | Necrosis, tadpole cells and atypical keratinized cells |
| Neuroendocrine carcinoma | Salt and pepper chromatin,anisonucleosis and rosettes |
| Small cell carcinoma | Absent cytoplasm, Smudge cells, and mitoses |
| Undifferentiated carcinoma | Pleomorphic cells, abundant necrosis |
| Spindle cell undifferentiated carcinoma | Undifferciated type with prominent spindle cells |
| Gaint cell undifferentiated carcinoma | Undifferentiated type with predominant giant cells |
References
- ↑ Jain, Deepali; Mathur, SandeepR; Sharma, Atul; Yadav, Rajni; Iyer, VenkateswaranK (2013). "Gallbladder carcinoma: An attempt of WHO histological classification on fine needle aspiration material". CytoJournal. 10 (1): 12. doi:10.4103/1742-6413.113627. ISSN 1742-6413.